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Cell Cycle Volume 12, 2013 - Issue 21
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Stem cell-like ALDHbright cellular states in EGFR-mutant non-small cell lung cancer: A novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

BRUNA COROMINAS-FAJA Metabolism & Cancer Group; Translational Research Laboratory; Catalan Institute of Oncology; Girona, Catalonia, Spain; Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain
,
Cristina Oliveras-Ferraros Metabolism & Cancer Group; Translational Research Laboratory; Catalan Institute of Oncology; Girona, Catalonia, Spain; Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain
,
ELISABET CUYÀS Metabolism & Cancer Group; Translational Research Laboratory; Catalan Institute of Oncology; Girona, Catalonia, Spain; Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain
,
Antonio Segura-Carretero Department of Analytical Chemistry; Faculty of Sciences; University of Granada; Granada, Spain
,
Jorge Joven Unitat de Recerca Biomèdica (URB-CRB); Institut d'Investigació Sanitaria Pere i Virgili (IISPV); Universitat Rovira i Virgili; Reus, Catalonia, Spain
,
Begoña Martin-Castillo Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain; Clinical Research Unit; Catalan Institute of Oncology; Girona, Catalonia, Spain
,
ENRIQUE BARRAJÓN-CATALÁN Molecular and Cellular Biology Institute (IBMC); Miguel Hernández University; Elche, Alicante, Spain; Monteloeder, Inc.; Elche, Alicante, Spain
,
Vicente Micol Molecular and Cellular Biology Institute (IBMC); Miguel Hernández University; Elche, Alicante, Spain; Monteloeder, Inc.; Elche, Alicante, Spain
,
Joaquim Bosch-Barrera Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain; Medical Oncology; Catalan Institute of Oncology; Girona, Catalonia, Spain
&
JAVIERABEL MENENDEZ MENENDEZ Girona Biomedical Research Institute (IDIBGI); Girona, Catalonia, Spain; Department of Analytical Chemistry; Faculty of Sciences; University of Granada; Granada, SpainCorrespondence[email protected]
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Pages 3390-3404 | Received 26 Aug 2013, Accepted 07 Sep 2013, Published online: 17 Sep 2013

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Asefeh Dahmardeh Ghalehno, Arad Boustan, Hakimeh Abdi, Zahra Aganj, Fatemeh Mosaffa & Khadijeh Jamialahmadi. (2022) The Potential for Natural Products to Overcome Cancer Drug Resistance by Modulation of Epithelial-Mesenchymal Transition. Nutrition and Cancer 74:8, pages 2686-2712.
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Elisabet Cuyàs, Almudena Pérez-Sánchez, Vicente Micol, Javier A. Menendez & Joaquim Bosch-Barrera. (2016) STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer. Cell Cycle 15:24, pages 3413-3418.
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Xupeng Bai, Yibei Chen, Xiangyu Hou, Min Huang & Jing Jin. (2016) Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters. Drug Metabolism Reviews 48:4, pages 541-567.
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Jiali Yang, Juan Chen, Jinxi He, Jing Li, Juan Shi, William C. Cho & Xiaoming Liu. (2016) Wnt signaling as potential therapeutic target in lung cancer. Expert Opinion on Therapeutic Targets 20:8, pages 999-1015.
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Xinghua Cheng & Haiquan Chen. (2014) Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives. OncoTargets and Therapy 7, pages 1689-1704.
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