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Research Article

In-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (Keflin)

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Pages 463-468 | Received 15 Apr 2005, Accepted 23 May 2005, Published online: 04 Oct 2008

Figures & data

Figure 1 Structure of keflin (Sodium salt).

Figure 1 Structure of keflin (Sodium salt).

Figure 2 Proposed structure of the metal (II) complexes of keflin.

Figure 2 Proposed structure of the metal (II) complexes of keflin.

Table I.  Physical and spectral data of the metal (II) complexes.

Table II.  Selected IR and UV–visible spectral data of keflin and its complexes.

Table III.  In-vitro antibacterial activity data of the keflin and metal (II) complexes.

Table IV.  Minimum inhibitory concentration (μM) of Keflin and its metal complexes against some selected bacterial species.

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