2,109
Views
24
CrossRef citations to date
0
Altmetric
Research Article

Antioxidant activity and in vitro inhibition of tumor cell growth by leaf extracts from the carob tree (Ceratonia siliqua)

, , , , , , & show all
Pages 721-728 | Received 29 Jul 2008, Accepted 15 Sep 2008, Published online: 24 Jun 2009

Figures & data

Table 1. Contents of total phenol compounds, condensed tannins and total flavonoids in methanol leaf extracts of male, female and hermaphrodite carob trees.

Table 2. DPPH radical scavenging activity of methanol leaf extracts from female, male and hermaphrodite carob trees, and pure polyphenolic compounds.

Table 3. Correlation coefficients (R) between radical scavenging activity (RSA), antioxidant activity (AA) and contents of total phenols (GAE), tannins (CE) and flavonoids (RE).

Figure 1. Antioxidant activity of methanol leaf extracts from female, male, and hermaphrodite carob trees, and of pure polyphenol compounds. Values represent means ± SD of three assessments of the percent inhibition of autoxidation of the linoleic acid/β-carotene emulsion. Extracts and phenol compounds were evaluated at final concentrations of 1 mg/mL. Values followed by different letters are significantly different at p < 0.05 (one-way ANOVA, Duncan’s new multiple range test).

Figure 1.  Antioxidant activity of methanol leaf extracts from female, male, and hermaphrodite carob trees, and of pure polyphenol compounds. Values represent means ± SD of three assessments of the percent inhibition of autoxidation of the linoleic acid/β-carotene emulsion. Extracts and phenol compounds were evaluated at final concentrations of 1 mg/mL. Values followed by different letters are significantly different at p < 0.05 (one-way ANOVA, Duncan’s new multiple range test).

Figure 2. Effect of treatment with methanol leaf extracts from female (A), hermaphrodite (B), and male (C) carob trees on cell proliferation. Each point represents the mean of three independent experiments.

Figure 2.  Effect of treatment with methanol leaf extracts from female (A), hermaphrodite (B), and male (C) carob trees on cell proliferation. Each point represents the mean of three independent experiments.

Table 4. Inhibitory concentrations (IC50) and maximal degree of inhibition (Max.) of methanol leaf extracts of female, hermaphrodite and male carob trees on HeLa cells.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.