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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 23, 2008 - Issue 1
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Research Article

In vitro inhibition of cytosolic carbonic anhydrases I and II by some new dihydroxycoumarin compounds

Ismet Basaran Department of Chemistry, Balikesir University Science & Art Faculty, CAGIS/Kampus, 10100, Balikesir, Turkey
,
Selma Sinan Department of Biology, Balikesir University Science & Art Faculty, CAGIS/Kampus, 10100, Balikesir, Turkey
,
Umit Cakir Department of Chemistry, Balikesir University Science & Art Faculty, CAGIS/Kampus, 10100, Balikesir, Turkey
,
Mustafa Bulut Science and Art Faculty, Department of Chemistry, Marmara University, Kadiköy, 81040, Istanbul, Turkey
,
Oktay Arslan Department of Chemistry, Balikesir University Science & Art Faculty, CAGIS/Kampus, 10100, Balikesir, Turkey
&
Ozen Ozensoy Department of Chemistry, Balikesir University Science & Art Faculty, CAGIS/Kampus, 10100, Balikesir, Turkey
Pages 32-36 | Received 16 Jan 2007, Accepted 08 Mar 2007, Published online: 04 Oct 2008

Figures & data

Scheme 1 Synthesis of the various dihydroxy-coumarin derivatives.

Scheme 1 Synthesis of the various dihydroxy-coumarin derivatives.

Table I.  IC50 values of cytosolic CA isozymes I and II with the phenold dscribed in the paper.

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