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Research Article

Molecular modelling of phthalates – PPARs interactions

, , , , , , , & show all
Pages 611-616 | Received 08 Nov 2007, Accepted 07 May 2008, Published online: 20 Oct 2008

Figures & data

Figure 1 Structures of DEHP, MEHP, TOTM, phthalic acid and AZ 242.

Figure 1 Structures of DEHP, MEHP, TOTM, phthalic acid and AZ 242.

Figure 2 Fraction of each species of MEHP versus pH.

Figure 2 Fraction of each species of MEHP versus pH.

Figure 3 Fraction of each species of phthalic acid versus pH.

Figure 3 Fraction of each species of phthalic acid versus pH.

Figure 4 Docking of phthalic acid (PA) into PPARα (a) and PPARγ (b) (hydrogen bonds are rendered as dashed yellow lines).

Figure 4 Docking of phthalic acid (PA) into PPARα (a) and PPARγ (b) (hydrogen bonds are rendered as dashed yellow lines).

Figure 5 Docking of MEHP into PPARα (a) and PPARγ (b) (hydrogen bonds are rendered as dashed yellow lines).

Figure 5 Docking of MEHP into PPARα (a) and PPARγ (b) (hydrogen bonds are rendered as dashed yellow lines).

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