Adverse Outcome Pathway for Antimicrobial Quaternary Ammonium Compounds

Figures & data

Figure 1. Adverse outcome pathway for qACs.

Table 1. DDEFs for QACs

Uncertainty Factor	Inhalation Route	Oral Route
Inter-species variability
Toxicokinetics	1	1
Toxicodynamics	1	1 to 3*
Inter-individual (intra-species) variability
Toxicokinetics	1	1
Toxicodynamics	3	3
Intermediate-to-long term exposures	1	1
OVERALL UF	3	3 to 10

* A value of 3 may be most appropriate given the limited data available on the alteration of microflora.

Data Availability Statement

The authors state that there is no data set associated with the paper.Data sharing is not applicable to this article as no new data were created or analyzed in this study.