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International Journal of Chronic Obstructive Pulmonary Disease Volume 13, 2018 - Issue
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Review

A time for everything and everything in its time – exploring the mechanisms underlying seasonality of COPD exacerbations

Alexander Hicks1 Clinical and Experimental Sciences, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK, [email protected];2 Southampton NIHR Respiratory Biomedical Research Centre, Southampton General Hospital, Southampton, UK, [email protected];3 National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care (NIHR CLAHRC) Wessex, Southampton General Hospital, Southampton, UK, [email protected]Correspondence[email protected]
,
Eugene Healy1 Clinical and Experimental Sciences, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK, [email protected]
,
Natasha Sandeman1 Clinical and Experimental Sciences, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK, [email protected]
,
Martin Feelisch1 Clinical and Experimental Sciences, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK, [email protected];2 Southampton NIHR Respiratory Biomedical Research Centre, Southampton General Hospital, Southampton, UK, [email protected]
&
Tom Wilkinson1 Clinical and Experimental Sciences, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK, [email protected];2 Southampton NIHR Respiratory Biomedical Research Centre, Southampton General Hospital, Southampton, UK, [email protected];3 National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care (NIHR CLAHRC) Wessex, Southampton General Hospital, Southampton, UK, [email protected];4 Wessex Investigational Sciences Hub, University of Southampton – Faculty of Medicine, Southampton General Hospital, Southampton, UK
Pages 2739-2749 | Published online: 05 Sep 2018

Figures & data

Figure 1 Abridged pictorial representation of factors contributing to seasonal variations in COPD exacerbations.

Abbreviations: UV, ultraviolet; Vit D, vitamin D; IL, interleukin; TNF, tumor necrosis factor.
Figure 1 Abridged pictorial representation of factors contributing to seasonal variations in COPD exacerbations.
 

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