Figures & data
Table 1 Probe and primer sets used in this study
Table 2 Effect on CYP1A2, CYP2B6, and CYP3A4 mRNA levels of 48-hour treatment with honokiol or the positive control (rifampicin, lansoprazole, or phenobarbital) in three human hepatocyte lines (HF382, HFC443, and HMC520)
Figure 1 Effects of honokiol (0.5, 5, and 50 μM) and positive controls (ie, rifampicin [10 μM], lansoprazole [10 μM], and phenobarbital [1 mM]), on CYP2C8, CYP2C9, CYP2C19, UGT1A1, UGT1A4, UGT1A9, UGT2B7, and SULT2A1 mRNA levels after 48-hour treatment in three human hepatocyte lines (HF382, HFC443, and HMC520). Data represent the mean ± standard deviation (n=3).
![Figure 1 Effects of honokiol (0.5, 5, and 50 μM) and positive controls (ie, rifampicin [10 μM], lansoprazole [10 μM], and phenobarbital [1 mM]), on CYP2C8, CYP2C9, CYP2C19, UGT1A1, UGT1A4, UGT1A9, UGT2B7, and SULT2A1 mRNA levels after 48-hour treatment in three human hepatocyte lines (HF382, HFC443, and HMC520). Data represent the mean ± standard deviation (n=3).](/cms/asset/3c0fcc82-0fc4-4509-a37d-455f5a4434be/dddt_a_72305_f0001_b.jpg)
Table 3 Effect on CYP1A2, CYP2B6, and CYP3A4 activities following 48-hour treatment with honokiol or the positive control (rifampicin, lansoprazole, or phenobarbital) in three human hepatocyte lines (HF382, HFC443, and HMC520)