Abstract
We discuss the clinical presentation, investigations carried out, and the management issues in an elderly patient with hemophagocytic lymphohistiocytosis (HLH). The HLH was associated with an underlying Epstein–Barr virus positive peripheral T-cell lymphoma, not otherwise specified, and the lymphomatous cells harbored translocation t(5;9)(q11.2:p24). The 9p24 region contains the JAK2 gene. The disease had a fulminant course.
Acknowledgement
We thank Dr. Ed Kanfer, Department of Haematology, Hammersmith Hospital for his critical comments.
Potential conflict of interest:
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