171
Views
3
CrossRef citations to date
0
Altmetric
Teaching case of the month

The Hammersmith hospital hematopathology case of the month: hemophagocytic lymphohistiocytosis secondary to Epstein–Barr virus associated T-cell lymphoma

, , , &
Pages 1127-1132 | Received 04 Feb 2011, Accepted 09 Feb 2011, Published online: 21 Mar 2011

References

  • Henter JI, Horne A, Arico M, HLH2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007:48:124–131.
  • Filipovich AH. Hemophagocytic lymphohistiocytosis (HLH) and related disorders. Hematology Am Soc Hematol Educ Program 2009:127–131.
  • Stebbing J, Ngan S, Ibrahim H, The successful treatment of haemophagocytic syndrome in patients with human immunodeficiency virus-associated multi-centric Castleman's disease. Clin Exp Immunol 2008;154:399–405.
  • Su IJ, Wang CH, Cheng AL, Chen RL. Hemophagocytic syndrome in Epstein-Barr virus-associated T-lymphoproliferative disorders: disease spectrum, pathogenesis, and management. Leuk Lymphoma 1995;19:401–406.
  • Falini B, Pileri S, Solas ID, Peripheral T-cell lymphoma associated with hemophagocytic syndrome. Blood 1990;75:434–444.
  • Savage KJ, Ferreri AJ, Zinzani PL, Pilkeri SA. Peripheral T-cell lymphoma - not otherwise specified. Crit Rev Oncol Hematol 2010 Aug 10. [Epub ahead of print]
  • Kagami Y, Suzuki R, Taji H, Nodal cytotoxic lymphoma spectrum: a clinicopathologic study of 66 patients. Am J Surg Pathol 1999;23:1184–1200.
  • Adelaide J, Perot C, A t(8;9) translocation with PCM-JAK2 fusion in a patient with T-cell lymphoma. Leukemia. 2006;20:536–537.
  • Jones JF, Shurin S, Abramowsky C, T-cell lymphoma containing Epstein–Barr viral DNA in patients with chronic Epstein–Barr virus infection. N Engl J Med 1988;318:733–741.
  • Masilamani M, Seydlitz E, Bastmeyer M, Illges H. T cell activation induced by cross linking CD3 and CD28 leads to silencing of Epstein-Barr virus/C3d receptor (CR2/CD21) gene and protein expression. Immunobiology 2002;206:528–536.
  • Langer R, Geissinger E, Rudiger T, Peripheral T-cell lymphoma with progression to a clonally related, Epstein Barr virus+, cytotoxic aggressive T-cell lymphoma: evidence for a secondary EBV infection of an established malignant T-cell clone. Am J Surg Pathol 2010;34:1382–1387.
  • Horne A, Janka G, Maarten Egeler R, Haematopoeitic stem cell transplantation in haemophagocytic lymphohistiocytosis. Br J Haematol 2005;129:622–630.
  • Imashuku S. Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-HLH). J Pediatr Hematol Oncol 2011;33:35–39.
  • Matsumoto Y, Naniwa D, Banno S, The efficacy of therapeutic plasmapheresis for the treatment of fatal hemophagocytic syndrome: two case reports. Ther Apher 1998;2:300–304.
  • Petel Y, Alos N, Ansoborlo S, Dramatic efficacy of antithymocyte globulins in childhood EBV-associated haemophagocytic syndrome. Acta Paediatr 1997;86:911.
  • Olin R, Nichols K, Naghashpour M, Succesful use of the anti-CD25 antibody daclizumab in an adult patient with hemophagocyticlymphohistiocytosis. Am J Hematol 2008;83:747–749.
  • Imashuku S, Kuriyama K, Teramura T, Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytclymphohistoicytosis. J Clin Oncol 2001;19:2665–2673.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.