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Review Article

Strategies for oral delivery and mitochondrial targeting of CoQ10

Pages 1868-1881 | Received 13 Oct 2014, Accepted 27 Nov 2014, Published online: 29 Dec 2014

Figures & data

Figure 1. Structure of ubiquinone (CoQ10) and ubiquinol (CoQ10H2).

Figure 1. Structure of ubiquinone (CoQ10) and ubiquinol (CoQ10H2).

Figure 2. Therapeutic and clinical benefits of CoQ10.

Figure 2. Therapeutic and clinical benefits of CoQ10.

Figure 3. Physicochemical and physiological factors barriers against oral and targeted delivery of CoQ10.

Figure 3. Physicochemical and physiological factors barriers against oral and targeted delivery of CoQ10.

Figure 4. MitoQ10 obtained by chemical conjugation of CoQ10 and TPPBr for mitochondrial targeting.

Figure 4. MitoQ10 obtained by chemical conjugation of CoQ10 and TPPBr for mitochondrial targeting.

Figure 5. Mitochondrially targeted multifunctional CoQ10 nanosystems (TPPBr).

Figure 5. Mitochondrially targeted multifunctional CoQ10 nanosystems (TPPBr).

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