Figures & data
Figure 1. Effects of carbomer injection on intraocular pressure (IOP) in a 4 week time course in New Zealand rabbits.
Figure 2. (A) Effects of carbomer injection on nitrite levels in aqueous humour of rabbits, in a 4 week time-course; (B) Effects of carbomer injection on cGMP levels in aqueous humour in a 4 week time-course, in the rabbits used for glaucoma induction.
Figure 3. Effects of NCX250, at various concentrations (A), of DRZ (at various concentrations, (B) and comparison of NCX250 vs. DRZ 2% (C) on intraocular pressure (IOP) in carbomer-induced glaucoma in albino rabbits.
Figure 4. Effects of NCX250 2%, DRZ 2% and ISMN 2 % vs. vehicle, on intraocular pressure (IOP), in carbomer-induced glaucoma in albino rabbits in a 4 week time course.
Figure 5. Effect of NCX250 (2%) on cGMP (A) and nitrite (B) levels, in a carbomer-induced glaucoma in albino rabbits in a 4 week time-course.
Figure 6. Comparison between the effects of DRZ 2% and NCX250 2% on ocular hemodynamics (eco doppler).
Figure 7. Effect of NCX250 (2%), DRZ 2%, ISMN 2% vs. vehicle on apoptotic cell (Annexin V + 7-AAD) and cell concentration in aqueous humour of carbomer-induced glaucoma in albino rabbits.
Table 1. Total carbonic anhydrase (CA) activity in ciliary bodies of rabbits, with or without carbomer-induced glaucoma, and treated with various drugs (NCX250, DRZ, ISMN, at 2%)