Figures & data
Figure 1. The chemical structure of cinnamic acid derivatives and related compounds.
Figure 2. The percentage PTP1B inhibition of cinnamic acid derivatives and related compounds (100 µM). Data are expressed as mean ± SEM, n = 3.
Figure 3. Lineweaver-Burk plots for inhibitory activity of (A) o-hydroxycinnamic and (B) p-hydroxycinnamic on PTP1B.
Figure 4. The percentages of enzyme inhibition of SOV and its combination with o-hydroxycinnamic and p-hydroxycinnamic on PTP1B. (1): 0.012 µM SOV;(2): 25 μM o-hydroxycinnamic;(3): 25 μM o-hydroxycinnamic + 0.012 µM SOV;(4): 25 μM p-hydroxycinnamic; (5): 25 μM p-hydroxycinnamic + 0.012 µM SOV. Data are expressed as mean ±S.E.M., n =3. * P < 0.01, compared to SOV alone.
