3,945
Views
85
CrossRef citations to date
0
Altmetric
Hip

Postoperative blood transfusion strategy in frail, anemic elderly patients with hip fracture

The TRIFE randomized controlled trial

, &
Pages 363-372 | Received 07 Oct 2014, Accepted 01 Dec 2014, Published online: 14 Jan 2015

Figures & data

Figure 1. CONSORT flow diagram for enrollment, allocation, follow-up, and analysis

Figure 1. CONSORT flow diagram for enrollment, allocation, follow-up, and analysis

Table 1. Baseline characteristics of 284 frail elderly hip fracture patients

Table 2. Intention to treat: physical ability scores 10 days after hip fracture surgery compared in a restrictive transfusion group with a liberal group stratified in residents from nursing homes and sheltered housing and analyzed with Wilcoxon rank-sum test

Figure 2. Intention to treat: repeated measurements on recovery from physical disabilities before fracture until postoperative days 10, 30 and 90, presented as median score with interquartile range, in residents from nursing homes and sheltered housing facilities.

Figure 2. Intention to treat: repeated measurements on recovery from physical disabilities before fracture until postoperative days 10, 30 and 90, presented as median score with interquartile range, in residents from nursing homes and sheltered housing facilities.

Table 3. Hazards ratio of time to death within 30 and 90 days by intention-to-treat analysis and per-protocol analysis

Figure 3. Kaplan-Meier plots of 90-day survival rates after hip fracture in residents from nursing homes and sheltered housing facilities, by intention-to-treat analysis.

Figure 3. Kaplan-Meier plots of 90-day survival rates after hip fracture in residents from nursing homes and sheltered housing facilities, by intention-to-treat analysis.

Table 4. Causes of death over 90 postoperative days in frail, elderly hip fracture patients

Figure 4 Mean hemoglobin concentrations (in g/dL) measured on days 3, 10, 17, 24, and 30 after hip fracture surgery (with 95% confidence intervals) according to blood transfusion strategy (liberal or restrictive).

Figure 4 Mean hemoglobin concentrations (in g/dL) measured on days 3, 10, 17, 24, and 30 after hip fracture surgery (with 95% confidence intervals) according to blood transfusion strategy (liberal or restrictive).