3,945
Views
85
CrossRef citations to date
0
Altmetric
Hip

Postoperative blood transfusion strategy in frail, anemic elderly patients with hip fracture

The TRIFE randomized controlled trial

, &
Pages 363-372 | Received 07 Oct 2014, Accepted 01 Dec 2014, Published online: 14 Jan 2015

  • Bailey RA, Reardon G, Wasserman MR, McKenzie RS, Hord RS. Association of anemia with worsened activities of daily living and health-related quality of life scores derived from the minimum data set in long-term care residents. Health and Qual Life Outcomes 2012; 10, 129
  • Baker NL, Cook MN, Arrighi HM, Bullock R. Hip fracture risk and subsequent mortality among alzheimer’s disease patients in the United Kingdom. 1988–2007. Age Ageing 2011; 40 (1): 49-54.
  • Beaupre LA, Jones CA, Johnston DW, Wilson DM, Majumdar SR. Recovery of function following a hip fracture in geriatric ambulatory persons living in nursing homes: Prospective cohort study. J Am Geriatr Soc 2012; 60 (7): 1268-73.
  • Berry SD, Samelson EJ, Bordes M, Broe K, Kiel DP. Survival of aged nursing home residents with hip fracture. J Gerontol A Biol Sci Med Sci 2009; 64 (7): 771-77.
  • Bjorkelund KB, Hommel A, Thorngren KG, Lundberg D, Larsson S. Factors at admission associated with 4 months outcome in elderly patients with hip fracture. AANA J 2009; 77 (1): 49-58.
  • Carson JL, Terrin ML, Noveck H, Sanders DW, Chaitman BR, Rhoads GG, et al. Liberal or restrictive transfusion in high-risk patients after hip surgery. NEJM 2011; 365 (26): 2453-62.
  • Carson JL, Carless PA, Hebert PC. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. The Cochrane Database of Systematic Reviews 2012; 4, CD002042.
  • Carson JL, Brooks MM, Abbott JD, Chaitman B, Kelsey SF, Triulzi DJ, et al. Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease. Am Heart J 2013; 165 (6): 964-71.
  • Danish Health and Medicine Authority. Guidelines no. 10333 Blood transfusion 2008. Retrieved december/20, 2007. Available from http://www.sst.dk/Tilsyn/Transfusionsmedicin
  • Foss NB, Kehlet H. Mortality analysis in hip fracture patients: Implications for design of future outcome trials. Br J Anaesth 2005; 94 (1): 24-29.
  • Foss NB, Kehlet H. Hidden blood loss after surgery for hip fracture. J Bone Joint Surg Br 2006; 88 (8): 1053-59.
  • Foss NB, Kristensen MT, Jensen PS, Palm H, Krasheninnikoff M, Kehlet H. The effect of liberal versus restrictive transfusion tresholds on ambulation after hip fracture surgery. Transfusion 2009; 49: 227-34.
  • Gregersen M, Zintchouk D, Borris LC, Damsgaard EM. A geriatric multidisciplinary and tailor-made hospital-at-home method in nursing home residents with hip fracture. Geriatr Orthop Surg Rehabil 2011; 2 (4): 148-54.
  • Gregersen M, Morch MM, Hougaard K, Damsgaard EM. Geriatric intervention in elderly patients with hip fracture in an orthopedic ward. J Inj Violence Res 2012; 4 (2): 45-51.
  • Haentjens P, Magaziner J, Colon-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, et al. Meta-analysis: Excess mortality after hip fracture among older women and men. Ann Intern Med 2010; 152 (6): 380-90.
  • Halm EA, Wang JJ, Boockvar K, Penrod J, Silberzweig SB, Magaziner J, et al. The effect of perioperative anemia on clinical and functional outcomes in patients with hip fracture. J Orthop Trauma 2004; 18 (6): 369-74.
  • Hebért PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. NEJM 1999; 340 (6): 409-17.
  • Helweg-Larsen K. The Danish Register of Causes of Death. Scand J Public Health 2011; 39 (Suppl 7): 26–29
  • Holvik K, Ranhoff AH, Martinsen MI, Solheim LF. Predictors of mortality in older hip fracture inpatients admitted to an orthogeriatric unit in Oslo. Norway. J Aging Health 2010; 22 (8): 1114-31.
  • Izuel RM, Garcia Erce JA, Gomez-Barrera M, Cuenca Espierrez J, Abad Sazatornil R, Rabanaque Hernandez MJ. Relationship between allogeneic blood transfusion, iron deficiency and nosocomial infection in patients with hip fracture. [Relacion de la transfusion y la ferropenia con la infeccion nosocomial en pacientes con fractura de cadera] Med Clin (Barc) 2008; 131 (17): 647-52.
  • Juliebo V, Krogseth M, Skovlund E, Engedal K, Wyller TB. Medical treatment predicts mortality after hip fracture. J Gerontol A Biol Sci Med Sci 2010; 65 (4): 442-49.
  • Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B. Excess mortality in men compared with women following a hip fracture. national analysis of comedications, comorbidity and survival. Age Ageing 2010; 39 (2): 203-09.
  • Kirkland LL, Kashiwagi DT, Burton MC, Cha S, Varkey P. The Charlson comorbidity index score as a predictor of 30-day mortality after hip fracture surgery. Am J Med Qual 2011; 26 (6): 461-67.
  • Kristjansson SR, Ronning B, Hurria A, Skovlund E, Jordhoy MS, Nesbakken A, et al. A comparison of two pre-operative frailty measures in older surgical cancer patients. J Geriatric Oncology 2012; 3 (1): 1-7.
  • Kumar D, Mbako AN, Riddick A, Patil S, Williams P. On admission haemoglobin in patients with hip fracture. Injury 2011; 42 (2): 167-70.
  • Lawrence VA, Silverstein JH, Cornell JE, Pederson T, Noveck H, Carson JL. Higher hb level is associated with better early functional recovery after hip fracture repair. Transfusion 2003; 43 (12): 1717-22.
  • Lee KH, Ha YC, Lee YK, Kang H, Koo KH. Frequency, risk factors, and prognosis of prolonged delirium in elderly patients after hip fracture surgery. Clin Orthop Relat Res 2011; 469 (9): 2612-20.
  • Maraldi C, Volpato S, Cesari M, Cavalieri M, Onder G, Mangani I, et al. Anemia and recovery from disability in activities of daily living in hospitalized older persons. J Am Geriatr Soc 2006; 54 (4): 632-36.
  • Marcantonio ER, Goldman L, Orav EJ, Cook EF, Lee TH. The association of intraoperative factors with the development of postoperative delirium. Am J Med 1998; 105 (5): 380-84.
  • Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, et al. Timing matters in hip fracture surgery: Patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PloS One 2012; 7 (10): e46175.
  • Onem Y, Terekeci H, Kucukardali Y, Sahan B, Solmazgul E, Senol MG, et al. Albumin, hemoglobin, body mass index, cognitive and functional performance in elderly persons living in nursing homes. Arch Gerontol Geriatr 2010; 50 (1): 56-59.
  • Ortiz-Alonso FJ, Vidan-Astiz M, Alonso-Armesto M, Toledano-Iglesias M, Alvarez-Nebreda L, Branas-Baztan F, et al. The pattern of recovery of ambulation after hip fracture differs with age in elderly patients. J Gerontol A Biol Sci Med Sci 2012; 67 (6): 690-97.
  • Parker M. Randomised trial of blood transfusion versus a restrictive transfusion policy after hip fracture surgery. Injury 2013; 44 (12):1916-18.
  • Penninx BW, Pahor M, Cesari M, Corsi AM, Woodman RC, Bandinelli S, et al. Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc 2004; 52 (5): 719-24.
  • Petersen MB, Jorgensen HL, Hansen K, Duus BR. Factors affecting postoperative mortality of patients with displaced femoral neck fracture. Injury 2006; 37 (8): 705-11.
  • Public Health and Quality Improvement, Central Denmark Region. TrialPartner. Retrieved Nov/24, 2014. Available from www.cfk.rm.dk/om+os/forskning+og+kvalitetsudvikling/datamanagement/trialpartner.
  • Ryg J, Rejnmark L, Overgaard S, Brixen K, Vestergaard P. Hip fracture patients at risk of second hip fracture: A nationwide population-based cohort study of 169,145 cases during 1977–2001. J Bone Miner Res 2009; 24 (7): 1299-1307.
  • Salpeter SR, Buckley JS, Chatterjee S. Impact of more restrictive blood transfusion strategies on clinical outcomes: A meta-analysis and systematic review. Am J Med 2014; 127 (2): 124; 131.e3.
  • Schaller F, Sidelnikov E, Theiler R, Egli A, Staehelin HB, Dick W, et al. Mild to moderate cognitive impairment is a major risk factor for mortality and nursing home admission in the first year after hip fracture. Bone 2012; 51 (3): 347-52.
  • Tolson D, Rolland Y, Katz PR, Woo J, Morley JE, Vellas B. An international survey of nursing homes. JAMDA 2013; 14 (7): 459-62.
  • van Dijk PT, Mehr DR, Ooms ME, Madsen R, Petroski G, Frijters DH, et al. Comorbidity and 1-year mortality risks in nursing home residents. J Am Geriatr Soc 2005; 53 (4): 660-65.
  • WHO. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity 2011. Retrieved Apr/2, 2014. Available from www.who.int/vmnis/indicators/haemoglobin