Free radical theory of apoptosis and metamorphosis

Masayasu InoueDepartment of Biochemistry & Molecular Pathology Osaka City University Medical School, Osaka , Japan

Eisuke F. SatoDepartment of Biochemistry & Molecular Pathology Osaka City University Medical School, Osaka , Japan

Manabu NishikawaDepartment of Biochemistry & Molecular Pathology Osaka City University Medical School, Osaka , Japan

Keiichi HiramotoDepartment of Biochemistry & Molecular Pathology Osaka City University Medical School, Osaka , Japan

Akihiko KashiwagiInstitute for Amphibian Biology Graduate School of Science, Hiroshima University, Hiroshima , Japan

Kozo UtsumiInstitute of Medical Science Kurashiki Medical Center, Kurashiki , Japan

Abstract

Reactive oxygen species (ROS) are the major factors that induce oxidative modification of DNA and gene mutation. ROS can elicit oxidative stress and affect a wide variety of physiological and pathological processes including embryonal development, maturation and aging.

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Free radical theory of apoptosis and metamorphosis

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Free radical theory of apoptosis and metamorphosis

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