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the fate of foreign compounds in biological systems
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RESEARCH ARTICLE

Monomethyl Auristatin E (MMAE), a Payload for Multiple Antibody Drug Conjugates (ADCs), Demonstrates Differential Red Blood Cell Partitioning Across Human and Animal Species

Victor Yipa Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA94080
,
Ola M. Saadb BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA94080
,
Doug Leipolda Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA94080
,
Chunze Lic Clinical Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA94080
,
Amrita Kamatha Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA94080
&
Ben-Quan Shena Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, CA94080Correspondence[email protected] [email protected]
Received 15 Feb 2024, Accepted 17 Apr 2024, Accepted author version posted online: 22 Apr 2024
Accepted author version

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