Retroviral MDR1 gene transfer into marrow-engrafting human peripheral blood progenitor cells results in preferential transgene expression in the immature myeloid compartment rather than in mature myeloid progeny in vivo

Ec Buss Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany

S Laufs Research Program Innovative Cancer Diagnostics and Therapy, German Cancer Research Center, Heidelberg, Germany

S Naundorf Somatic Gene Therapy, EUFETS AG, Idar-Oberstein, Germany

K Kuehlcke Somatic Gene Therapy, EUFETS AG, Idar-Oberstein, Germany

Kz Nagy Research Program Innovative Cancer Diagnostics and Therapy, German Cancer Research Center, Heidelberg, Germany

Wj Zeller Research Program Innovative Cancer Diagnostics and Therapy, German Cancer Research Center, Heidelberg, Germany

Prof. Dr S Fruehauf Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany; Center for Tumor Diagnostics and Therapy, Paracelsus Klinik, Osnabrueck, GermanyCorrespondence[email protected]

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Retroviral MDR1 gene transfer into marrow-engrafting human peripheral blood progenitor cells results in preferential transgene expression in the immature myeloid compartment rather than in mature myeloid progeny in vivo

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Retroviral MDR1 gene transfer into marrow-engrafting human peripheral blood progenitor cells results in preferential transgene expression in the immature myeloid compartment rather than in mature myeloid progeny in vivo

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