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Journal of Enzyme Inhibition Volume 15, 2000 - Issue 4
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Original Article

Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes

Claudiu T. Supuran Laboratorio di Chimica Inorganica e Bioinorganica, Università degli Studi, Via Gino Capponi 7, I-50121, Florence, ItalyCorrespondence[email protected]
,
Andrea Scozzafava Laboratorio di Chimica Inorganica e Bioinorganica, Università degli Studi, Via Gino Capponi 7, I-50121, Florence, Italy
,
Marc A. Ilies Department of Chemistry, Faculty of Biotechnologies, University of Agricultural Sciences and Veterinary Medicine, B-dul Marasti nr. 59, 71331, Bucharest, Roumania
&
Fabrizio Briganti Laboratorio di Chimica Inorganica e Bioinorganica, Università degli Studi, Via Gino Capponi 7, I-50121, Florence, Italy
Pages 381-401 | Received 24 Sep 1999, Published online: 02 Jul 2010

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