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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Paper

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug

BoRa Leea Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, KoreaView further author information
,
Dae Gyu Kimb Medicinal Bioconvergence Research Center, Institute for Artificial Intelligence and Biomedical Research, College of Pharmacy and College of Medicine, Interdisciplinary Biomedical Center, Gangnam Severance Hospital, Yonsei University, Seoul, KoreaView further author information
,
Aram Leea Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, KoreaView further author information
,
Young Mi Kima Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, KoreaView further author information
,
Lianji Cuia Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, KoreaView further author information
,
Sunghoon Kimb Medicinal Bioconvergence Research Center, Institute for Artificial Intelligence and Biomedical Research, College of Pharmacy and College of Medicine, Interdisciplinary Biomedical Center, Gangnam Severance Hospital, Yonsei University, Seoul, KoreaCorrespondence[email protected]
View further author information
&
Inhee Choia Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7884-1764View further author information
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Pages 51-66 | Received 05 Aug 2022, Accepted 08 Oct 2022, Published online: 28 Oct 2022

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