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Research Paper
Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators
Mohammed Farrag El-Behairya Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufiya, Egypthttps://orcid.org/0000-0001-7843-1423View further author information
, Walaa Hamada Abd-Allahb Pharmaceutical Chemistry Department, Collage of Pharmaceutical Science and Drug Manufacturing, Misr University for Science and Technology, Giza, EgyptView further author information
, Mohamed M. Khalifac Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypthttps://orcid.org/0000-0002-8146-993XView further author information
, Mohamed S. Nafied Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypthttps://orcid.org/0000-0003-4454-6390View further author information
, Mohamed A. Salehe Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, The United Arab Emirates;f Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptView further author information
, Mohammed S. Abdel-Maksoudg Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), Giza, EgyptView further author information
, Tarfah Al-Warhih Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaView further author information
, Wagdy M. Eldehnai Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypthttps://orcid.org/0000-0001-6996-4017View further author information
& Ahmed A. Al‐Karmalawyj Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, EgyptCorrespondence[email protected]
https://orcid.org/0000-0002-8173-6073View further author information
show allhttps://orcid.org/0000-0002-8173-6073View further author information
Article: 2157825
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Received 24 Sep 2022, Accepted 07 Dec 2022, Published online: 11 Jan 2023
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