Journal of Enzyme Inhibition and Medicinal Chemistry
Volume 38, 2023 - Issue 1
Research Paper
Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation
Hend Kothayera Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, EgyptCorrespondence[email protected] [email protected]
https://orcid.org/0000-0002-2954-0751View further author information
https://orcid.org/0000-0002-2954-0751View further author information, Samar Rezqb Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt;c Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA;d Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS, USA;e Women’s Health Research Center, University of Mississippi Medical Center, Jackson, MS, USA;f Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, MS, USAhttps://orcid.org/0000-0003-4421-0686View further author information
https://orcid.org/0000-0003-4421-0686View further author information, Ahmed S. Abdelkhaleka Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypthttps://orcid.org/0000-0003-2198-0549View further author information
https://orcid.org/0000-0003-2198-0549View further author information, Damian G. Romeroc Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA;d Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS, USA;e Women’s Health Research Center, University of Mississippi Medical Center, Jackson, MS, USA;f Cardiovascular-Renal Research Center, University of Mississippi Medical Center, Jackson, MS, USAhttps://orcid.org/0000-0002-7268-9690View further author information
https://orcid.org/0000-0002-7268-9690View further author information & Samar S. Elbaramawia Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypthttps://orcid.org/0000-0001-8658-1296View further author information
https://orcid.org/0000-0001-8658-1296View further author information