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Research Article
Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers
Samar El-Kalyoubia Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University, Port Said, EgyptView further author information
, Mohamed M. Khalifab Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptView further author information
, Mahmoud T. Abo-Elfadlc Biochemistry Department, Biotechnology Research Institute, National Research Centre, Cairo, Egypt;d Cancer Biology and Genetics Laboratory, Centre of Excellence for Advanced Sciences, National Research Centre, Cairo, EgyptView further author information
, Ahmed A. El-Sayede Photochemistry Department, Chemical Industries Research Institute, National Research Centre, Giza, EgyptView further author information
, Ahmed Elkamhawyf College of Pharmacy, BK21 FOUR Team and Integrated Research Institute for Drug Development, Dongguk University—Seoul, Goyang, Republic of Korea;g Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptCorrespondence[email protected]
View further author information
, View further author information
Kyeong Leef College of Pharmacy, BK21 FOUR Team and Integrated Research Institute for Drug Development, Dongguk University—Seoul, Goyang, Republic of KoreaView further author information
& Ahmed A. Al-Karmalawyh Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, 6th of October City, Giza, Egypthttps://orcid.org/0000-0002-8173-6073View further author information
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Article: 2242714
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Received 24 May 2023, Accepted 26 Jul 2023, Published online: 18 Aug 2023
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