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Key Paper Evaluation

Good results for early treatment of clinically isolated syndrome prior to multiple sclerosis with interferon beta-1b and glatiramer group

Evaluation of: Kappos L, Freedman MS, Edan G, et al. Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the Phase III BENEFIT trial. Lancet Neurol 2009;8:987-997, and Comi G, Martinelli V, Rodgeher M, et al. Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomized, double-blind, placebo-controlled trial. Lancet 2009;374:1503-1511.

, PhD DSc
Pages 1225-1230 | Published online: 15 Mar 2010

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