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Expert Opinion on Pharmacotherapy Volume 11, 2010 - Issue 14

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Key Paper Evaluation

Does the p38 MAP kinase inhibitor pamapimod have potential for the treatment of rheumatoid arthritis?

Evaluation of: Zhang X, Huang Y, Navarro M, et al. A proof-of-concept and drug–drug interaction of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis. J Clin Pharmacol 2010. [Epub ahead of print] and Alten RE, Zerbini C, Jeka S, et al. Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy. Ann Rheum Dis 2010;69:364-7.

Sheila A Doggrell

, PhD DSc &

Anne-Marie Christensen Queensland University of Technology, Discipline of Medical Sciences, Faculty of Science and Technology, GPO 2343, QLD 4001, Brisbane, Australia +61 7 3138 2015; +61 7 3138 1534; [email protected]

, MAppSc

Pages 2437-2442 | Published online: 29 Jul 2010

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https://doi.org/10.1517/14656566.2010.507631

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