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Expert Opinion on Pharmacotherapy Volume 7, 2006 - Issue 12
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Key Paper Evaluation

Natalizumab in multiple sclerosis: proceed with caution?

POLMAN CH, O’CONNOR PW, HAVRDOVA E et al.: A randomised, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. (2006) 354:899-910, RUDICK RA, STUART WH, CALABRESI PA et al.: Natalizumab plus interferon-b1a for relapsing multiple sclerosis. N. Engl. J. Med. (2006) 354:911-923, and YOUSRY TA, MAJOR EO, RYSCHKEWITSCH C et al.: Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N. Engl. J. Med. (2006) 354:924-933.

Sheila A Doggrell Senior Lecturer, School of Science, Charles Darwin University, PO Box 41246, Casuarina, Northern Territory, 0811 Australia. [email protected]
Pages 1675-1678 | Published online: 28 Jul 2006

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