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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 5
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Animal Pharmacokinetics and Metabolism

A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data

Kotaro OgawaPre-clinical Research Department, Chugai Pharmaceuticals Co., Ltd., Gotemba, Shizuoka, JapanCorrespondence[email protected]
,
Motohiro KatoPre-clinical Research Department, Chugai Pharmaceuticals Co., Ltd., Gotemba, Shizuoka, Japan
,
Takao HoujoChugai Research Institute for Medical Science, Inc., Gotemba, Shizuoka, Japan
&
Masaki IshigaiPre-clinical Research Department, Chugai Pharmaceuticals Co., Ltd., Gotemba, Shizuoka, Japan
Pages 468-478 | Received 01 Aug 2012, Accepted 21 Sep 2012, Published online: 15 Nov 2012

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