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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 12
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Research Article

Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline

Masahiro UtohShin Nippon Biomedical Laboratories, Ltd., Pharmacokinetics and Bioanalysis Center KainanJapan;Showa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapan
,
Norie MurayamaShowa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapan
,
Yasuhiro UnoShin Nippon Biomedical Laboratories, Ltd., Pharmacokinetics and Bioanalysis Center KainanJapan
,
Yui OnoseShowa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapan
,
Shinya HosakaShowa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapan
,
Hideki FujinoSchool of Pharmacy, Hyogo University of Health Sciences KobeJapan
,
Makiko ShimizuShowa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapan
,
Kazuhide IwasakiShin Nippon Biomedical Laboratories, Ltd., Pharmacokinetics and Bioanalysis Center KainanJapan
&
Hiroshi YamazakiShowa Pharmaceutical University, Laboratory of Drug Metabolism and Pharmacokinetics MachidaJapanCorrespondence[email protected]
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Pages 1037-1042 | Received 01 Mar 2013, Accepted 04 Apr 2013, Published online: 16 May 2013

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