Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans

Michelle Franz-MontanDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil, Correspondence[email protected]

Daniela BaroniDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil,

Giovana BrunettoDepartment of Biochemistry, Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, and

Viviane Roberta Vieira SobralDepartment of Biochemistry, Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, and

Camila Morais Gonçalves da SilvaDepartment of Biochemistry, Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, and

Paulo VenâncioDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil,

Patricia Wiziack ZagoDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil,

Cintia Maria Saia CeredaDepartment of Biochemistry, Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, and

Maria Cristina VolpatoDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil,

Daniele Ribeiro de AraújoHuman and Natural Sciences Centre, Federal University of ABC, São Paulo, Brazil

Eneida de PaulaDepartment of Biochemistry, Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, and

Francisco Carlos GroppoDepartment of Physiological Sciences, Piracicaba Dental School, University of Campinas – UNICAMP, Piracicaba, São Paulo, Brazil,

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Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans

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Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans

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