Inhibitory Effect of Nigella sativa on Histamine (H1) Receptors of Isolated Guinea Pig Tracheal Chains

References

• Ansari AK, Sadiy HAS (1989): Structural studies on a saponin isolated from the seeds of Nigella sativa. Phytochemistry 27: 377–379.
   Google Scholar
• Mel MB (1992a): The relaxing effect of volatile oil of Nigella sativa seed on vascular smooth muscle. Jordan Ser B 1: 91–100.
   Google Scholar
• Mel MB (1992b): The calcium antagonistic effect of the volatile oil of Nigella Sativa seeds. Jordan Ser B 1: 119–133.
   Google Scholar
• Mel MB (1993): Effects of Nigella sativa seeds on intestinal smooth muscle. Int J Pharmacogn 31: 55–60.
   Google Scholar
• Ariens EJ (1987): in Nadel JA, Pauwels R, Snashall PD (eds). Bronchial Hyperresponsiveness, London, Blackwell Scien-tific Publications, pp. 7–23.
   Google Scholar
• Arunlakshana 0, Schild HO (1959): Some quantitive use of drug antagonists. Br J Phamacol 14: 48–58.
   Google Scholar
• Atta UR, Malik SO (1985): Nigellimine N-oxide, a new isoquinoline alkaloid from the seeds of Nigella sativa. Heterocycles 23: 953–955.
   Google Scholar
• Atta UR, Malik SO (1995): Nigellidine, a new indazol alkaloid from seeds of Nigella sativa. J Res Inst 36: 1993–1996. Avesina (1990): Law in Medicine, Interpreter; Sharafkhandy A. Theran, Ministry of Guidance publication, p. 314.
   Google Scholar
• Bogats LN, Epshtein MiM (1959): Effect of a-pinen on the chemoreceptor function of the peripheral nerves. Fiziol-Zhur Akad Nauk Rse 5: 659–661.
   Google Scholar
• Boskabady MH, Shahabi M (1997): Bronchodilatory and anti-cholinergic effects of Nigella sativa on isolated guinea-pig tracheal chains. Iran J Med Sci 22: 127–133.
   Google Scholar
• Buckle DR, Arch JRS, Boering NE, Foster KA, Taylor JF, Taylor SG, Shaw DJ (1993): Relaxation effect of potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660. Pulm Pharma-col 6: 77–86.
   PubMedGoogle Scholar
• El-Dakhakhny M (1963): Studies on chemical constitution of Egyptian Nigella sativa L. seeds. II. The essential oil. Planta Med 11: 465–470.
   Google Scholar
• El-Tahir KEH, Ashour MIMS, Al-Harbi MiM (1993): The respi-ratory effect of the volatile oil of the black seed (Nigella sativa) in guinea-pig: elucidation of the mechanism(s) of action. Gen Pharmacol 24: 1115–1122.
   Google Scholar
• Holroyde, MC (1986): The influence of epithelium on the responsiveness of guinea-pig isolated trachea. Br J Phar-macol 87: 501–507.
   PubMed Web of Science ®Google Scholar
• Houghton PJ, Zarka R, de la Heras B, Hoult JRS (1995): Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoeid generation in leukocytes and membrane peroxidation. Planta Med 61: 33–36.
   PubMed Web of Science ®Google Scholar
• Linden A, Bergendal A, Ullman A, Skoogh BE, Lofdahl CG (1993a): Salmetrol, formetrol, and salbutamol in the iso-lated guinea-pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism. Thorax 48: 547–553.
   PubMed Web of Science ®Google Scholar
• Linden A, Lofdahl CG, Ullman A, Skoogh BE (1993b): Nonadrenergic noncholinergic responses stabilize smooth muscle tone with and without parasympathetic activation in guinea-pig isolated airways. Eur Respir J 6: 425–433.
   PubMed Web of Science ®Google Scholar
• Mahfouz M, El-Dakhakhny M (1960): Chemical and pharma-cological properties of the new anti-asthmatic drug, nigel-lone. Egypt Pharm Bull 42: 411–424.
   Google Scholar
• Meini S, Ballati L, Evangelista S, Manzini S (1993): Isbufulline, a xanthine derivative, inhibits bronchoconstrictor responses produced by stimulation of capsaicin sensitive nerves in guinea-pig, in vitro and in vivo evidence. Pulm Pharmacol 6: 279–286.
   PubMedGoogle Scholar
• Miyahara Y, Kizawa Y, Sano M, Murakami H (1993): Effect of organic and inorganic Ca' antagonists on acetylcholine induced contraction in molluscan (Mytilus edulis) smooth muscle. Gen Pharmacol 24: 1419–1423.
   PubMedGoogle Scholar
• Popa VT (1977): Bronchodilatory activity of an H1 blocker chlorpheniramine. J Allergy Clin Immuno 59: 54–63.
   PubMed Web of Science ®Google Scholar
• Reiter M, Brandt W (1985): Relaxant effects on tracheal and ileal smooth muscles of the guinea-pig. Arzneim Forsch/Drug Res 35: 408–414.
   PubMed Web of Science ®Google Scholar
• Van Amsterdam RGM, Meurs H, Brouwer F, Postema JIB, Timmermans A, Zaagsma J (1989): Role of phospho-inosited metabolism in functional antagonism of airway smooth muscle contraction by beta-adrenoceptor agonist. Eur J Pharmacol 172: 175–183.
   PubMed Web of Science ®Google Scholar