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New Zealand Journal of Agricultural Research Volume 66, 2023 - Issue 6
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Review articles

Intended and unintended consequences of genetically modified crops – myth, fact and/or manageable outcomes?

John R. CaradusGrasslanz Technology Ltd, Palmerston North, New ZealandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7887-9041
ORCID Icon
Pages 519-619 | Received 18 Aug 2022, Accepted 25 Oct 2022, Published online: 08 Nov 2022

References

  • ABARES. 2018. Australian crop report. Prepared by the Australian Bureau of Agricultural and Resource Economics and Sciences. No. 188. 30 pp. [accessed 2022 July 10]. https://www.agriculture.gov.au/sites/default/files/abares/documents/AustCropRrt20181204_v1.0.0.pdf.
  • Addae PC, Ishiyaku MF, Tignegre JB, Ba MN, Bationo JB, Atokple ID, Abudulai M, Dabiré-Binso CL, Traore F, Saba M, et al. 2020. Efficacy of a cry1Ab gene for control of Maruca vitrata (Lepidoptera: Crambidae) in Cowpea (Fabales: Fabaceae). J Econ Entomol. 113:974–979. doi:10.1093/jee/toz367.
  • Adekambi SA, Okello JJ, Rajendran S, Acheremu K, Carey EE, Low J, Abidin PE. 2020. Effect of varietal attributes on the adoption of an orange-fleshed sweet potato variety in Upper East and Northern Ghana. Outlook Agric. 49:311–320. doi:10.1177/0030727020950324.
  • Adenle AA. 2011. Global capture of crop biotechnology in developing world over a decade. J Gen Eng Biotechnol. 9:83–95.
  • Agapito-Tenfen SZ, Vilperte V, Benevenuto RF, Rover CM, Traavik TI, Nodari RO. 2014. Effect of stacking insecticidal cry and herbicide tolerance epsps transgenes on transgenic maize proteome. BMC Plant Biol. 14:Article 346. doi:10.1186/s12870-014-0346-8.
  • Agostini LP, Dettogni RS, Dos Reis RS, Stur E, Dos Santos EV, Ventorim DP, Garcia FM, Cardoso RC, Graceli JB, Louro ID. 2020. Effects of glyphosate exposure on human health: insights from epidemiological and in vitro studies. Sci Total Environ. 705:Article 135808. doi:10.1016/j.scitotenv.2019.135808.
  • Ahmad N, Raza G, Waheed T, Mukhtar Z. 2021. Food safety issues and challenges of GM crops. In: Singh P, Borthakur A, Singh AA, Kumar A, Singh KK, editors. Policy issues in genetically modified crops. Academic Press; p. 355–369. doi:10.1016/B978-0-12-820780-2.00016-9.
  • Akram MZ, Yaman S, Jalal H, Doğan SC, Shahid S, Ali BS. 2019. Effects of feeding genetically modified crops to domestic animals: a review. Turk J Agric-Food Sci Technol. 7:110–118. doi:10.24925/turjaf.v7isp1.110-118.2773.
  • Ali I, Zhang S, Muhammad MS, Naranjo SE, Li Y, Bigler F. 2018. Bt proteins have no detrimental effects on larvae of the green lacewing, Chrysopa pallens (Rambur) (Neuroptera: Chrysopidae). Neotrop Entomol. 47:336–343. doi:10.1007/s13744-017-0526-y.
  • Ali S, Nawaz MA, Ghufran M, Hussain SN, Mohammed ASH. 2021. GM trust shaped by trust determinants with the impact of risk/benefit framework: the contingent role of food technology neophobia. GM Crops Food. 12:170–191. doi:10.1080/21645698.2020.1848230.
  • Alston JM, Kalaitzandonakes N, Kruse J. 2014. Chapter 45. The size and distribution from the adoption of biotech soybean varieties. In: Smyth SJ, Phillips PWB, Castle D, editors. Handbook on agriculture, biotechnology and development. Cheltenham: Edward Elgar Publishing Ltd; p. 728–751.
  • Altieri M, Pengue W. 2006. GM soybean: Latin America’s new colonizer. Seedling. 1:13–17. http://www.grain.org/seedling/index.cfm?id=421&print=yes.
  • Altieri MA. 2003. The sociocultural and food security impacts of genetic pollution via transgenic crops of traditional varieties in Latin American Centers of Peasant Agriculture. Bull Sci Technol Soc. 23:350–359. doi:10.1177/0270467603259774.
  • Alvarez M, Guelman S, Halford NG, Lustig S, Reggiardo MI, Ryabushkina N, Shewry P, Stein J, Vallejos RH. 2000. Silencing of HMW glutenins in transgenic wheat expressing extra HMW subunits. Theor Appl Genet. 100:319–327. doi:10.1007/s001220050042.
  • Amin MR, Oh S, Park SY, Ha K, Kang S, Park J-H, Kim M, Eun CU, Kim YK, Suh SJ. 2022. The effect of thioredoxin-gene-expressed transgenic soybean on associated non-target insects and arachnids. Plant Biotechnol Rep. 16:79–90. doi:10.1007/s11816-021-00724-y.
  • Ammann K. 2005. Effects of biotechnology on biodiversity: herbicide-tolerant and insect-resistant GM crops. TRENDS Biotechnol. 23:388–394. doi:10.1016/j.tibtech.2005.06.008.
  • Ammann K, Jacot Y, Al Mazyad PR. 1994. Safety of genetically engineered plants: an ecological risk assessment of vertical gene flow. Molecular Ecol. 3:1–30. http://www.ask-force.org/web/VIB/Ammann-Outcrossing-Overview-VIB-final-20001215.pdf.
  • Anderson K, Jackson LA, Nielsen CP. 2005. GM rice adoption: impact for welfare and poverty alleviation. J Econ Integr. 20:125–134. https://www.jstor.org/stable/23000670.
  • Areal FJ, Riesgo L, Rodríguez-Cerezo E. 2011. Attitudes of European farmers towards GM crop adoption. Plant Biotechnol J. 9:945–957. doi:10.1111/j.1467-7652.2011.00651.x.
  • Areal FJ, Riesgo L, Rodríguez-Cerezo E. 2013. Economic and agronomic impact of commercialized GM crops: a meta-analysis. J Agric Sci. 151:7–33.
  • Arjo G, Portero M, Piñol C, Viñas J, Matias-Guiu X, Capell T, Bartholomaeus A, Parrott W, Christou P. 2013. Plurality of opinion, scientific discourse and pseudoscience: an in depth analysis of the Séralini et al. study claiming that Roundup™ ready corn or the herbicide Roundup™ cause cancer in rats. Transgenic Res. 22:255–267. doi:10.1007/s11248-013-9692-9.
  • Arntzen CJ, Coghlan A, Johnson B, Peacock J, Rodemeyer M. 2003. GM crops: science, politics and communication. Nat Rev Genetics. 4:839–43.
  • Arujanan M, Aldemita RR. 2015. Evolution of agriculture and the crop technologies. In: James C, Teng P, Arujanan M, Aldemita RR, Flavell RB, Brookes G, Qaim M, editors. Invitational essays to celebrate the 20th anniversary of the commercialization of biotech crops (1996 to 2015): progress and promise. International Service for the Acquisition of Agri-Biotech Applications (ISAAA) Brief 51. Ithaca (NY): ISAAA; p. 13–27.
  • Asif MA, Zafar Y, Iqbal J, Iqbal MM, Rashid U, Ali GM, Arif A, Nazir F. 2011. Enhanced expression of AtNHX1, in transgenic groundnut (Arachis hypogaea L.) improves salt and drought tolerance. Mol Biotechnol. 49:250–256. doi:10.1007/s12033-011-9399-1.
  • Aslam S, Gul N. 2020. Impact of genetically modified crops on environment. In: Singh R, Shukla P, Singh P, editor. Environmental processes and management. Water Science and Technology Library, Vol. 91. Cham: Springer; p. 237–248. doi:10.1007/978-3-030-38152-3_13.
  • Azad MA, Amin L, Sidik NM. 2014. Gene technology for Papaya Ringspot virus disease management. Sci World J. 2014:11 pages. doi:10.1155/2014/768038.
  • Babendreier D, Reichhart B, Romeis J, Bigler F. 2008. Impact of insecticidal proteins expressed in transgenic plants on bumblebee microcolonies. Entomol Experiment Applic. 126:148–157. doi:10.1111/j.1570-7458.2007.00652.x.
  • Bacalhau FB, Dourado PM, Horikoshi RJ, Carvalho RA, Semeão A, Martinelli S, Berger GU, Head GP, Salvadori JR, Bernardi O. 2020. Performance of genetically modified soybean expressing the Cry1A.105, Cry2Ab2, and Cry1Ac proteins against key lepidopteran pests in Brazil. J Econ Entomol. 113:2883–2889. doi:10.1093/jee/toaa236.
  • Bagla P. 2010. Hardy cotton-munching pests are latest blow to GM crops. Science. 327:1439–1439. https://www.science.org/doi/abs/10.1126science.327.5972.1439.
  • Bak A, Emerson JB. 2020. Cauliflower mosaic virus (CaMV) biology, management, and relevance to GM plant detection for sustainable organic agriculture. Front Sustain Food Syst. 4:Article 21. doi:10.3389/fsufs.2020.00021.
  • Bakhsh A, Hussain T, Rahamkulov I, Demirel U, Çalışkan ME. 2020. Transgenic potato lines expressing CP4-EPSP synthase exhibit resistance against glyphosate. Plant Cell, Tissue Organ Culture. 140:23–34. doi:10.1007/s11240-019-01708-1.
  • Bakshi A. 2003. Potential adverse health effects of genetically modified crops. J Toxicol Environ Health Part B. 6:211–225. doi:10.1080/10937400306469.
  • Baltazar BM, Castro Espinoza L, Espinoza Banda A, de la Fuente Martínez JM, Garzón Tiznado JA, González García J, Antonio Gutiérrez M, Guzmán Rodríguez JL, Heredia Díaz O, Hora MJ, et al. 2015. Pollen-mediated gene flow in maize: implications for isolation requirements and coexistence in Mexico, the center of origin of maize. PLoS ONE. 10:Article e0131549. doi:10.1371/journal.pone.0131549.
  • Barona E, Ramankutty N, Hyman G, Coomes OT. 2010. The role of pasture and soybean in deforestation of the Brazilian Amazon. Environ Res Letters. 5:Article 024002. doi:10.1088/1748-9326/5/2/024002.
  • Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, Romero DA, Horvath P. 2007. CRISPR provides acquired resistance against viruses in prokaryotes. Science. 315:1709–1712.
  • Barros J, Temple S, Dixon RA. 2019. Development and commercialization of reduced lignin alfalfa. Current Opinion Biotechnol. 56:48–54. doi:10.1016/j.copbio.2018.09.003.
  • Barrows G, Sexton S, Zilberman D. 2014a. Agricultural biotechnology: the promise and prospects of genetically modified crops. J Econ Perspect. 28:99–120. https://pubs.aeaweb.org/doi/pdfplus/10.1257jep.28.1.99.
  • Barrows G, Sexton S, Zilberman D. 2014b. The impact of agricultural biotechnology on supply and land-use. Environ Develop Econ. 19:676–703. doi:10.1017/S1355770X14000400.
  • Bartholomaeus A, Parrott W, Bondy G, Walker K. 2013. The use of whole food animal studies in the safety assessment of genetically modified crops: limitations and recommendations. Critical Rev Toxicol. 43:1–24. doi:10.3109/10408444.2013.842955.
  • Bashir K, Husnain T, Fatima T, Latif Z, Mehdi S, Riazuddin S. 2004. Field evaluation and risk assessment of transgenic Indica basmati rice. Molecul Breeding. 13:301–12. doi:10.1023/B:MOLB.0000034078.54872.25.
  • Bates S, Zhao JZ, Roush R, Shelton AM. 2005. Insect resistance management in GM crops: past, present and future. Nat Biotechnol. 23:57–62. doi:10.1038/nbt1056.
  • Baulcombe D, Dunwell J, Jones J, Pickett J, Puigdomenech P. 2014. GM science update: a report to the Council for Science and Technology. [accessed 2022 July 16]. https://centaur.reading.ac.uk/36228/1/GM%20Science%20Update%20-%20Report%20to%20CST%20110314.pdf.
  • Beckie HJ, Busi R, Lopez-Ruiz FJ, Umina PA. 2021. Herbicide resistance management strategies: how do they compare with those for insecticides, fungicides and antibiotics? Pest Manag Sci. 77:3049–3056. doi:10.1002/ps.6395.
  • Beckmann V, Soregaroli C, Wesseler J. 2006. Coexistence rules and regulations in the European Union. Amer J Agric Econ. 88:1193–1199. http://www.jstor.org/stable/4123591.
  • Beckmann V, Soregaroli C, Wesseler J. 2010. Ex-ante regulation and ex-post liability under uncertainty and irreversibility: governing the coexistence of GM crops. Economics. 4:1–33. doi:10.5018/economics-ejournal.ja.2010-9.
  • Beechey-Gradwell Z, Kadam S, Bryan G, Cooney L, Nelson K, Richardson K, Cookson R, Winichayakul S, Reid M, Anderson P, et al. 2022. Lolium perenne engineered for elevated leaf lipids exhibits greater energy density in field canopies under defoliation. Field Crops Res. 275:Article 108340.
  • Belcher K, Nolan J, Phillips PW. 2005. Genetically modified crops and agricultural landscapes: spatial patterns of contamination. Ecol Econ. 53:387–401.
  • Bell E, Nakai S, Burzio LA. 2018. Stacked genetically engineered trait products produced by conventional breeding reflect the compositional profiles of their component single trait products. J Agric Food Chem. 66:7794–7804. doi:10.1021/acs.jafc.8b02317.
  • Benbrook C. 2000. Who controls and who will benefit from plant genomics? Invited paper AAAS Annual Meeting, 2000 Genome Seminar. Pp. 28. [accessed 2022 June 17]. https://www.researchgate.net/profile/Charles-Benbrook/publication/237418578_The_2000_Genome_Seminar_Genomic_Revolution_in_the_Fields_Facing_the_Needs_of_the_New_Millennium/links/02e7e53681d8f214a8000000/The-2000-Genome-Seminar-Genomic-Revolution-in-the-Fields-Facing-the-Needs-of-the-New-Millennium.pdf.
  • Benbrook C. 2001. Do GM crops mean less pesticide use? Pesticide Outlook; p. 204–207. https://pubs.rsc.org/en/content/articlepdf/2001/po/b108609j.
  • Benbrook C. 2012. Impacts of genetically engineered crops on pesticide use in the U.S. – the first sixteen years. Environ Sci Eur. 24:Article 24. doi:10.1186/2190-4715-24-24.
  • Bennett PM, Livesey CT, Nathwani D, Reeves DS, Saunders JR, Wise R. 2004b. An assessment of the risks associated with the use of antibiotic resistance genes in genetically modified plants: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrobial Chemotherapy. 53:418–431. doi:10.1093/jac/dkh087.
  • Bennett R, Ismael Y, Morse S. 2005. Explaining contradictory evidence regarding impacts of genetically modified crops in developing countries. Varietal performance of transgenic cotton in India. J Agric Sci. 143:35–41. doi:10.1017/S002185960500506X.
  • Bennett R, Ismael Y, Morse S, Shankar B. 2004a. Reductions in insecticide use from adoption of Bt cotton in South Africa: impacts on economic performance and toxic load to the environment. J Agricul Sci. 142:665–74. doi:10.1017/S0021859605004892.
  • Bennett R, Morse S, Ismael Y. 2006. The economic impact of genetically modified cotton on South African smallholders: yield, profit and health effects. J Develop Studies. 42:662–677. doi:10.1080/00220380600682215.
  • Beringer JE. 2000. Releasing genetically modified organisms: will any harm outweigh any advantage? J Appl Ecol. 37:207–214.
  • Berman KH, Harrigan GG, Nemeth MA, Oliveira WS, Berger GU, Tagliaferro FS. 2011. Compositional equivalence of insect-protected glyphosate-tolerant soybean MON 87701 × MON 89788 to conventional soybean extends across different world regions and multiple growing seasons. J Agric Food Chem. 59:11643–1151. doi:10.1021/jf202782z.
  • Bernstein JA, Bernstein IL, Bucchini L, Goldman LR, Hamilton RG, Lehrer S, Rubin C, Sampson HA. 2003. Clinical and laboratory investigation of allergy to genetically modified foods. Environ Health Perspectives. 111:1114–1121. doi:10.1289/ehp.5811.
  • Betz FS, Hammond BG, Fuchs RL. 2000. Safety and advantages of Bacillus thuringiensis-protected plants to control insect pests. Reg Toxicol Pharmacol. 32:156–173. doi:10.1006/rtph.2000.1426.
  • Beyer P. 2010. Golden Rice and ‘Golden’ crops for human nutrition. New Biotechnol. 27:478–481.
  • Bhalla PL. 2006. Genetic engineering of wheat – current challenges and opportunities. TRENDS Biotechnol. 24:305–311. doi:10.1016/j.tibtech.2006.04.008.
  • Bhatt B, Bhatt D, Bhatt MD, Karkute SG, Singh PM, Singh J, Singh AK. 2022. Biotechnological Innovations in Cucumber (Cucumis sativus L.) development – current scenario and future perspectives. In: The cucumber genome 2022. Cham: Springer; p. 185–199. doi:10.1007/978-3-030-88647-9_13.
  • Biden S, Smyth SJ, Hudson D. 2018. The economic and environmental cost of delayed GM crop adoption: the case of Australia's GM canola moratorium. GM Crops & Food. 9:13–20. doi:10.1080/21645698.2018.1429876.
  • Binder S, Isbell F, Polasky S, Catford JA, Tilman D. 2018. Grassland biodiversity can pay. Proc Natl Acad Sci USA. 115:3876–3881. www.pnas.org/cgi/doi/10.1073pnas.1712874115.
  • Blair R, Regenstein M. 2020. GM food and human health. In: Andersen V, editor. Genetically modified and irradiated food. Academic Press; p. 69–98. doi:10.1016/B978-0-12-817240-7.00005-X.
  • Blanco CA, Chiaravalle W, Dalla-Rizza M, Farias JR, García-Degano MF, Gastaminza G, Mota-Sánchez D, Murúa MG, Omoto C, Pieralisi BK, et al. 2016. Current situation of pests targeted by Bt crops in Latin America. Current Opinion Insect Sci. 15:131–138. doi:10.1016/j.cois.2016.04.012.
  • Blechl AE, Anderson OD. 1996. Expression of a novel high-molecular-weight glutenin subunit gene in transgenic wheat. Nat Biotechnol. 14:875–879. doi:10.1038/nbt0796-875.
  • Blesh J, Hoey L, Jones AD, Friedmann H, Perfecto I. 2019. Development pathways toward “zero hunger”. World Dev. 118:1–14. doi:10.1016/j.worlddev.2019.02.004.
  • Boedeker W, Watts M, Clausing P, Marquez E. 2020. The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review. BMC Public Health. 20:Article 1875. doi:10.1186/s12889-020-09939-0.
  • Bøhn T, Millstone E. 2019. The introduction of thousands of tonnes of glyphosate in the food chain – an evaluation of glyphosate tolerant soybeans. Foods. 8:Article 669. doi:10.3390/foods8120669.
  • Bolhaar ST, van de Weg WE, van Ree R, Gonzalez-Mancebo E, Zuidmeer L, Bruijnzeel-Koomen CA, Fernandez-Rivas M, Jansen J, Hoffmann-Sommergruber K, Knulst AC, Gilissen LJ. 2005. In vivo assessment with prick-to-prick testing and double-blind, placebo-controlled food challenge of allergenicity of apple cultivars. J Allergy Clinical Immunol. 11:1080–1086. doi:10.1016/j.jaci.2005.07.004.
  • Bonny S. 2008. Genetically modified glyphosate-tolerant soybean in the USA: adoption factors, impacts and prospects. A review. Agron Sustain Dev. 28:21–32. doi:10.1051/agro:2007044.
  • Bonny S. 2011. Herbicide-tolerant transgenic soybean over 15 years of cultivation: pesticide use, weed resistance, and some economic issues. The case of the USA. Sustainability. 3:1302–1322. doi:10.3390/su3091302.
  • Borch K, Rasmussen B. 2002. Commercial use of GM crop technology: identifying the drivers using life cycle methodology in a technology foresight framework. Technol Forecast Social Change. 69:765–780.
  • Borch K, Rasmussen B. 2005. Refining the debate on GM crops using technological foresight – the Danish experience. Technol Forecast Social Change. 72:549–566.
  • Bouis HE. 2007. The potential of genetically modified food crops to improve human nutrition in developing countries. J Dev Stud. 43:79–96. doi:10.1080/00220380601055585.
  • Bourguet D, Desquilbet M, Lemarié S. 2005. Regulating insect resistance management: the case of non-Bt corn refuges in the US. J Environ Management. 76:210–220. doi:10.1016/j.jenvman.2005.01.019.
  • Bowers E. 2022. Impact of non-GM livestock and poultry feed on the U.S. feed industry. [accessed 2022 June 25]. http://ifeeder.org/wp-content/uploads/IFEEDER-final-report-1.18.22-FINAL.pdf.
  • Bowman DT, May OL, Creech JB. 2003. Genetic uniformity of the US upland cotton crop since the introduction of transgenic cottons. Crop Sci. 43:515–518. doi:10.2135/cropsci2003.5150.
  • Brake DG, Evenson DP. 2004. A generational study of glyphosate-tolerant soybeans on mouse fetal, postnatal, pubertal and adult testicular development. Food Chem Toxicol. 42:29–36.
  • Brinch-Pedersen H, Borg S, Tauris B, Holm PB. 2007. Molecular genetic approaches to increasing mineral availability and vitamin content of cereals. J Cereal Sci. 46:308–326. doi:10.1016/j.jcs.2007.02.004.
  • Brookes DR, Bohan DA, Champion GT, Haughton AJ, Hawes C, Heard MS, Clark SJ, Dewar AM, Firbank LG, Perry JN. 2003. Invertebrate responses to the management of genetically modified herbicide–tolerant and conventional spring crops. I. Soil-surface-active invertebrates. Philosophical Transactions of the Royal Society of London. Series B: Biolog Sci. 358:1847–1862. doi:10.1098/rstb.2003.1407.
  • Brookes G. 2014. Weed control changes and genetically modified herbicide tolerant crops in the USA 1996–2012. GM Crops Food. 5:321–332. doi:10.4161/21645698.2014.958930.
  • Brookes G. 2022. Farm income and production impacts from the use of genetically modified (GM) crop technology 1996–2020. GM Crops Food. 13:171–195. doi:10.1080/21645698.2022.2105626.
  • Brookes G, Barfoot P. 2003. GM rice: will this lead the way for global acceptance of GM crop technology? International Service for the Acquisition of Agri-biotech Applications (ISAAA) Briefs No. 28. Ithaca (NY): International Service for the Acquisition of Agri-Biotech Applications; p. 1–62.
  • Brookes G, Barfoot P. 2015. GM crops: global socio-economic and environmental impacts 1996–2013: impacts on pesticide use and carbon emissions. Dorchester: PG Economics Ltd. p. 1–196. [accessed 2022 July 16]. doi:10.1080/21645698.2015.1025193.
  • Brookes G, Barfoot P. 2017. GM crops: global socio-economic and environmental impacts 1996–2015. Dorchester: PG Economics Ltd; p. 1–201. [accessed 2022 July 16]. https://www.bezpecnostpotravin.cz/UserFiles/publikace/2017globalimpactstudy.pdf.
  • Brookes G, Barfoot P. 2020a. GM crops: global socio-economic and environmental impacts 1996–2018. [accessed 2022 June 9]. https://www.pgeconomics.co.uk/pdf/globalimpactfinalreportJuly2020.pdf.
  • Brookes G, Barfoot P. 2020b. GM crop technology use 1996–2018: farm income and production impacts. GM Crops & Food. 11:242–261.
  • Brookes G, Barfoot P. 2020c. Environmental impacts of genetically modified (GM) crop use 1996–2018: impacts on pesticide use and carbon emissions. GM Crops & Food. 11:215–241.
  • Brown JL, Stobart R, Hallett PD, Morris NL, George TS, Newton AC, Valentine TA, McKenzie BM. 2021. Variable impacts of reduced and zero tillage on soil carbon storage across 4–10 years of UK field experiments. J Soils Sediments. 21:890–904. doi:10.1007/s11368-020-02799-6.
  • Bruening G, Lyons J. 2000. The case of the FLAVR SAVR tomato. Calif Agr. 54:6–7. https://calag.ucanr.edu/Archive/?article=ca.v054n04p6.
  • Buiatti M, Christou P, Pastore G. 2013. The application of GMOs in agriculture and in food production for a better nutrition: two different scientific points of view. Genes Nutr. 8:255–270. doi:10.1007/s12263-012-0316-4.
  • Bull SE, Seung D, Chanez C, Mehta D, Kuon J-E, Truernit E, Hochmuth A, Zurkirchen I, Zeeman SC, Gruissem W, Vanderschuren H. 2018. Accelerated ex situ breeding of GBS- and PTST1-edited cassava for modified starch. SciAdv. 4:Article eaat6086. https://www.science.org/doi/abs/10.1126sciadv.aat6086.
  • Bullock DS, Nitsi EI. 2001. Roundup-Ready soybean technology and farm production costs: measuring the incentive to adopt genetically modified seeds. Amer Behav Scient. 44:1283–1301. doi:10.1177/00027640121956827.
  • Burd AD, Gould F, Bradley JR, Van Duyn JW, Moar WJ. 2003. Estimated frequency on non-recessive Bt resistance genes in bollworm, Helioverpazea (Boddie) (Lepidoptera: Noctuidae) in Eastern North Carolina. J Econ Entomol. 96:137–142. doi:10.1093/jee/96.1.137.
  • Burke D. 2004. GM food and crops: what went wrong in the UK? Many of the public's concerns have little to do with science. EMBO Reports. 5:432–436. doi:10.1038/sj.embor.7400160.
  • Buzoianu SG, Walsh MC, Rea MC, Cassidy JP, Ryan TP, Ross RP, Gardiner GE, Lawlor PG. 2013a. Transgenerational effects of feeding genetically modified maize to nulliparous sows and offspring on offspring growth and health. J Anim Sci. 91:318–320. doi:10.2527/jas.2012-5360.
  • Buzoianu SG, Walsh MC, Rea MC, Quigley L, O’ Sullivan O, Cotter PD, Ross RP, Gardiner GE, Lawlor PG. 2013b. Sequence-based analysis of the intestinal microbiota of sows and their offspring fed genetically modified maize expressing a truncated form of Bacillus thuringiensis Cry1Ab protein (Bt maize). Appl Environ Microbiol. 79:7735–7744. doi:10.1128/AEM.02937-13.
  • Cao J, Zhao JZ, Tang J, Shelton AM, Earle ED. 2002. Broccoli plants with pyramided cry1Ac and cry1C Bt genes control diamondback moths resistant to Cry1A and Cry1C proteins. Theor Appl Genet. 105:258–264. doi:10.1007/s00122-002-0942-0.
  • Cao Y, Li D. 2013. Impact of increased demand for animal protein products in Asian countries: implications on global food security. Animal Frontiers. 3:48–55. doi:10.2527/af.2013-0024.
  • Caradus J. 2022. Impacts of growing and utilising genetically modified crops and forages – a New Zealand perspective. NZ J Agric Res. doi:10.1080/00288233.2022.2077380.
  • Caradus JR, Goldson SL, Moot DJ, Rowarth JS, Stewart AV. 2022a. Pastoral agriculture, a significant driver of New Zealand’s economy, based on an introduced grassland ecology and technological advances. J Royal Soc NZ. doi:10.1080/03036758.2021.2008985.
  • Caradus JR, Lovatt S, Belgrave B. 2013. Adoption of forage technologies. Proc NZ Grassl Assoc. 75:39–44. doi:10.33584/jnzg.2013.75.2917.
  • Caradus JR, Voisey CR, Cousin GR, Kaur R, Woodfield DR, Blanc A, Roldan MB. 2022b. The hunt for the “holy grail”: condensed tannins in the perennial forage legume white clover (Trifolium repens L.). Grass Forage Sci. 77:111–123. doi:10.1111/gfs.12567.
  • Carlson AB, Mukerji P, Mathesius CA, Huang E, Herman RA, Hoban D, Thurman JD, Roper JM. 2020. DP-2Ø2216-6 maize does not adversely affect rats in a 90-day feeding study. Regulatory Toxicol. & Pharmacol. 117:Article 104779. doi:10.1016/j.yrtph.2020.104779.
  • Carman J. 2004. Is GM food safe to eat. In: Hindmarsh R, Lawrence G, editors. Recoding nature: critical perspectives on genetic engineering. Sydney: University of New South Wales Press; p. 82–93 and 228–229. ISBN 0 86840 741 0.
  • Carman JA, Vlieger HR, Ver Steeg LJ, Sneller VE, Robinson GW, Clinch-Jones CA, Haynes JI, Edwards JW. 2013. A long-term toxicology study on pigs fed a combined genetically modified (GM) soy and GM maize diet. J Organic Systems. 8:38–54.
  • Carpenter JE. 2010. Peer-reviewed surveys indicate positive impact of commercialized GM crops. Nat Biotechnol. 28:320–321.
  • Carriere Y, Brown ZS, Downes SJ, Gujar G, Epstein G, Omoto C, Storer NP, Mota-Sanchez D, Jørgensen PS, Carroll SP. 2020. Governing evolution: a socioecological comparison of resistance management for insecticidal transgenic Bt crops among four countries. Ambio. 49:1–16. doi:10.1007/s13280-019-01167-0.
  • Carzoli AK, Aboobucker SI, Sandall LL, Lübberstedt TT, Suza WP. 2018. Risks and opportunities of GM crops: Bt maize example. Global Food Security. 19:84–91.
  • Castaldini M, Turrini A, Sbrana C, Benedetti A, Marchionni M, Mocali S, Fabiani A, Landi S, Santomassimo F, Pietrangeli B, et al. 2005. Impact of Bt corn on rhizospheric and soil eubacterial communities and on beneficial mycorrhizal symbiosis in experimental microcosms. Appl Environ Microbiol. 71:6719–6729.
  • Castiglioni P, Warner D, Bensen RJ, Anstrom DC, Harrison J, Stoecker M, Abad M, Kumar G, Salvador S, D'Ordine R, et al. 2008. Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited conditions. Plant Physiol. 147:446–455. doi:10.1104/pp.108.118828.
  • Cattaneo MG, Yafuso C, Schmidt C, Huang CY, Rahman M, Olson C, Ellers-Kirk C, Orr BJ, Marsh SE, Antilla L, Dutilleul P. 2006. Farm-scale evaluation of the impacts of transgenic cotton on biodiversity, pesticide use, and yield. Proc Natl Acad Sci. 103:7571–6. doi:10.1073/pnas.0508312103.
  • Cayford J. 2004. Breeding sanity into the GM food debate. Issues in Science and Technology. 20:49–56. [accessed 2022 May 8]. https://www.jstor.org/stable/43312428.
  • Cerdeira AL, Duke SO. 2006. The current status and environmental impacts of glyphosate-resistant crops: a review. J Environ Qual. 35:1633–1658. doi:10.2134/jeq2005.0378.
  • Challa S, Neelapu NRR, Dutta T, Mishra MR. 2020. Involvement of policymakers, public acceptance, and commercialization of nutritionally enhanced and genetically modified rice. In: Roychoudhury A, editor. Rice research for quality improvement: genomics and genetic engineering. Singapore: Springer; p. 749–780. doi:10.1007/978-981-15-5337-0_34.
  • Chan RL, Trucco F, Otegui ME. 2020. Why are second-generation transgenic crops not yet available in the market? J Exptal Bot. 71:6876–6880. doi:10.1093/jxb/eraa412.
  • Chang J, Clay DE, Hansen SA, Clay SA, Schumacher TE. 2014. Water stress impacts on transgenic drought-tolerant corn in the northern Great Plains. Agron J. 106:125–130. doi:10.2134/agronj2013.0076.
  • Chassy BM. 2010. Food safety risks and consumer health. New Biotechnol. 27:534–544.
  • Chaudhuri A, Datta A. 2018. Genetically modified (GM) crops: a potential source to combat global hunger and malnutrition. Austin J Nutri Food Sci. 6:Article 1106.
  • Chavas J-P, Shi G, Lauer J. 2014. The effects of GM technology on maize yield. Crop Sci. 54:1331–1335. doi:10.2135/cropsci2013.10.0709.
  • Che J, Zhu YL, Li YH, Zhang R, Ruan ZY, Zhang W. 2022. Response of bacterial communities in saline-alkali soil to different pesticide stresses. Environ Sci Pollut Res. 29:42709–42719. doi:10.1007/s11356-021-16316-w.
  • Cheeke TE, Pace BA, Rosenstiel TN, Cruzan MB. 2011. The influence of fertilizer level and spore density on arbuscular mycorrhizal colonization of transgenic Bt 11 maize (Zea mays) in experimental microcosms. FEMS Microbiol Ecol. 75:304–312.
  • Chen HW, Do YY, Huang PL, Wu MT. 2014. Current developments in genetically modified bananas. J Taiwan Soc Horticult Sci. 60:1–10.
  • Chen M, Zhao J-Z, Collins HL, Earle ED, Cao J, Shelton AM. 2008. A critical assessment of the effects of Bt transgenic plants on parasitoids. PLoS ONE. 3:Article e2284. doi:10.1371/journal.pone.0002284.
  • Chetty L, Viljoen CD. 2007. GM biotechnology: friend and foe? Sth Afr J Sci. 103:269–270. https://hdl.handle.net/10520/EJC96707.
  • Christey M, Woodfield D. 2001. Coexistence of genetically modified and non-genetically modified crops. Crop & Food Research Confidential Report No. 427, p. 1–71. Report prepared for the Ministry for the Environment. June 2001. [accessed 2022 June 18]. https://environment.govt.nz/assets/Publications/Files/coexistence-feb01.pdf.
  • Christou P, Capell T, Kohli A, Gatehouse JA, Gatehouse AM. 2006. Recent developments and future prospects in insect pest control in transgenic crops. Trends Plant Sci. 11:302–308. doi:10.1016/j.tplants.2006.04.001.
  • Christou P, Twyman RM. 2004. The potential of genetically enhanced plants to address food insecurity. Nutr Res Rev. 17:23–42. doi:10.1079/NRR200373.
  • Chudnovsky D. 2006. Argentina: adopting RR soy, economic liberalization, global markets and socio-economic consequences. In: Fukuda-Parr S, editor. Gene revolution: GM crops and unequal development. London: Earthscan Publications; p. 85–103.
  • Chulze SN. 2010. Strategies to reduce mycotoxin levels in maize during storage: a review. Food Add Contam. Part A. 27:651–657. doi:10.1080/19440040903573032.
  • Chvatalova V. 2020. Czech Farmers’ experience with Bt maize: fulfillment, and the opposite, of Monsanto's promises. Acta Univ Agric Silvicult Mendel Brunen. 68:25–38. doi:10.11118/actaun202068010025.
  • Chvatalova V. 2021. The post-market environmental monitoring of GM maize in the EU has a limited capacity to identify adverse effects. Environ Sci Pol. 121:11–17. doi:10.1016/j.envsci.2021.03.013.
  • Clark BW, Phillipes TA, Coates JR. 2005. Environmental fate and effects of Bacillus thuringiensis (Bt) protein from transgenic crops: a review. J Agric Food Chem. 53:4643–53. doi:10.1021/jf040442k.
  • Clasen BM, Stoddard TJ, Luo S, Demorest ZL, Li J, Cedrone F, Tibebu R, Davison S, Ray EE, Daulhac A, et al. 2016. Improving cold storage and processing traits in potato through targeted gene knockout. Plant Biotechnol J. 14:169–176. doi:10.1111/pbi.12370.
  • Clawson EL, Perrett JJ, Cheng L, Ahmad A, Stojsin D, McGowan Y, Heredia Díaz O, Asim M, Vertuan H, Quddusi M, Soares DJ. 2019. Consistent risk assessment outcomes from agronomic characterization of GE maize in diverse regions and as single-event and stacked products. Crop Sci. 59:1681–91. doi:10.2135/cropsci2018.12.0758.
  • Coca M, Peñas G, Gómez J, Campo S, Bortolotti C, Messeguer J, San Segundo B. 2006. Enhanced resistance to the rice blast fungus Magnaporthe grisea conferred by expression of a cecropin A gene in transgenic rice. Planta. 223:392–406. doi:10.1007/s00425-005-0069-z.
  • Cohen MB, Chen M, Bentur JS, Heong KL, Ye G. 2008. Bt rice in Asia: potential benefits, impact, and sustainability. In: Romeis J, Shelton AM, Kennedy GG, editors. Integration of insect-resistant genetically modified crops within IPM programs. Prog Biol Contr. 5. Dordrecht: Springer; p. 223–248. doi:10.1007/978-1-4020-8373-0_8.
  • Collinge DB, Jørgensen HJ, Lund OS, Lyngkjær MF. 2010. Engineering pathogen resistance in crop plants: current trends and future prospects. Ann Rev Phytopathol. 48:269–291. doi:10.1146/annurev-phyto-073009-114430.
  • Collinge DB, Sarrocco S. 2022. Transgenic approaches for plant disease control: status and prospects 2021. Plant Pathol. 71:207–225. doi:10.1111/ppa.13443.
  • Conner AJ, Glare TR, Nap JP. 2003. The release of genetically modified crops into the environment: part II. Overview of ecological risk assessment. Plant J. 33:19–46. doi:10.1046/j.0960-7412.2002.001607.x.
  • Convention on Biological Diversity. 2022. Biosafety clearing house. [accessed 2022 May 29]. https://bch.cbd.int/en/search?currentPage=1&schema=modifiedOrganism.
  • Cook G, Pieri E, Robbins PT. 2004. The scientists think and the public feels: expert perceptions of the discourse of GM food. Discourse & Soc. 15:433–449. doi:10.1177/0957926504043708.
  • Coupe RH, Capel PD. 2016. Trends in pesticide use on soybean, corn and cotton since the introduction of major genetically modified crops in the United States. Pest Manag Sci. 72:1013–1022. doi:10.1002/ps.4082.
  • Craig W, Tepfer M, Degrassi G, Ripandelli D. 2008. An overview of general features of risk assessments of genetically modified crops. Euphytica. 164:853–880. doi:10.1007/s10681-007-9643-8.
  • Crawley M, Brown S, Hails R, Kohn DD, Rees M. 2001. Transgenic crops in natural habitats. Nature. 409:682–683. doi:10.1038/35055621.
  • Cruz-Reyes R, Ávila-Sakar G, Sánchez-Montoya G, Quesada M. 2015. Experimental assessment of gene flow between transgenic squash and a wild relative in the center of origin of cucurbits. Ecosphere. 6:1–13. doi:10.1890/ES15-00304.1.
  • Cuhra M. 2015. Review of GMO safety assessment studies: glyphosate residues in Roundup Ready crops is an ignored issue. Environ Sci Eur. 27:1–14. doi:10.1186/s12302-015-0052-7.
  • Cuker BE, Sharma I, Dorsey K, Stojilovic O, Smith N, Justice A. 2020. Pesticides bring the war on nature to the Chesapeake Bay. In: Cuker B, editor. Diet for a sustainable ecosystem. Estuaries of the world. Cham: Springer; p. 199–217. doi:10.1007/978-3-030-45481-4_11.
  • Cunliffe KV, Vecchie AC, Jones ES, Kearney GA, Forster JW, Spangenberg GC, Smith KF. 2004. Assessment of gene flow using tetraploid genotypes of perennial ryegrass (Lolium perenne L.). Aust J Agric Res. 55:389–396. doi:10.1071/AR03156.
  • Dahleen LS, Okubara PA, Blechl AE. 2001. Transgenic approaches to combat fusarium head blight in wheat and barley. Crop Sci. 41:628–37. doi:10.2135/cropsci2001.413628x.
  • Damalas CA, Eleftherohorinos LG. 2011. Pesticide exposure, safety issues, and risk assessment indicators. International Journal of Environ Res Pub Health. 8:1402–1419.
  • Daniell H, Streatfield SJ, Wycoff K. 2001. Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants. Trends Plant Sci. 6:219–226.
  • Davison J. 2010. GM plants: science, politics and EC regulations. Plant Science. 178:94–8. doi:10.1016/j.plantsci.2009.12.005.
  • Davoren MJ, Schiestl RH. 2018. Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research. Carcinogenesis. 39:1207–1215. doi:10.1093/carcin/bgy105.
  • Deb R, Raja TV, Chakraborty S, Gupta SK, Singh U. 2016. Chapter 25. Genetically modified crops: an alternative source of livestock feeding. In: Genetically modified organisms in food. p. 291–295. doi:10.1016/B978-0-12-802259-7.00025-7.
  • de Bakker E, Bogaardt MJ, van der Werff M, Beekman V. 2016. Benign or detrimental institutional environments for GM crops. LEI Wageningen UR. FOODSECURE project office Working Paper No. 54; p. 1–25. https://library.wur.nl/WebQuery/wurpubs/fulltext/408772.
  • de Cerqueira DTR, Schafer AC, Fast BJ, Herman RA. 2017. Agronomic performance of insect-protected and herbicide-tolerant MON 89034 × TC1507 × NK603 × DAS-40278–9 corn is equivalent to that of conventional corn. GM Crops Food. 8:149–55. doi:10.1080/21645698.2017.1301331.
  • Deen W, Kataki PK. 2003. Carbon sequestration in a long-term conventional versus conservation tillage experiment. Soil Tillage Res. 74:143–150. doi:10.1016/S0167-1987(03)00162-4.
  • DeFrancesco L. 2013. How safe does transgenic food need to be? Nat Biotechnol. 31:794–802. https://www.nature.com/articles/nbt.2686.pdf.
  • De Giacomo M, Di Domenicantonio C, De Santis B, Debegnach F, Onori R, Brera C. 2016. Carry-over of DNA from genetically modified soyabean and maize to cow’s milk. Journal of Animal Feed Sci. 25:109–115.
  • Deikman J, Petracek M, Heard JE. 2012. Drought tolerance through biotechnology: improving translation from the laboratory to farmers’ fields. Current Opinion Biotechnol. 23:243–250. doi:10.1016/j.copbio.2011.11.003.
  • De Leo F, Bonadé-Bottino MA, Ceci LR, Gallerani R, Jouanin L. 1998. Opposite effects on Spodoptera littoralis larvae of high expression level of a trypsin proteinase inhibitor in transgenic plants. Plant Physiol. 118:997–1004. doi:10.1104/pp.118.3.997.
  • De Lucas JA, Forster JW, Smith KF, Spangenberg GC. 2012. Assessment of gene flow in white clover (Trifolium repens L.) under field conditions in Australia using phenotypic and genetic markers. Crop Pasture Science. 63:155–163. doi:10.1071/CP11224.
  • Demont M, Dillen K. 2008. Herbicide tolerant sugar beet: the most promising first-generation GM crop? Internatl Sugar J. 110:613–617.
  • Demont M, Wesseler J, Tollens E. 2004. Biodiversity versus transgenic sugar beet: the one euro question. Europ Rev Agric Econ. 31:1–8. doi:10.1093/erae/31.1.1.
  • De Santis B, Stockhofe N, Wal JM, Weesendorp E, Lalles JP, van Dijk J, Kok E, De Giacomo M, Einspanier R, Onori R, Brera C. 2018. Case studies on genetically modified organisms (GMOs): potential risk scenarios and associated health indicators. Food Chem Toxicol. 117:36–65. doi:10.1016/j.fct.2017.08.033.
  • de Vendomois JS, Roullier F, Cellier D, Séralini GE. 2009. A comparison of the effects of three GM corn varieties on mammalian health. Int J Biol Sci. 5:706–726.
  • Devi R, Kaur M, Gosal SS. 2016. Generation of drought tolerance in Indica rice by introducing ZAT12 gene. Appl Biolog Res. 18:208–213. doi:10.5958/0974-4517.2016.00032.X.
  • Devine GJ, Furlong MJ. 2007. Insecticide use: contexts and ecological consequences. Agric Human Values. 24:281–306.
  • de Vos CJ, Swanenburg M. 2018. Health effects of feeding genetically modified (GM) crops to livestock animals: a review. Food Chem Toxicol. 117:3–12. doi:10.1016/j.fct.2017.08.031.
  • Devos Y, Demont M, Dillen K, Reheul D, Kaiser M, Sanvido O. 2009. Coexistence of genetically modified and non-GM crops in the European Union: a review. In: Lichtfouse E, Navarrete M, Debaeke P, Véronique S, Alberola C, editors. Sustainable agriculture. Dordrecht: Springer; p. 203–228. doi:10.1007/978-90-481-2666-8_14.
  • Dewar AM, Champion GT, May MJ, Pidgeon JD. 2005. The UK farm scale evaluations of GM crops – a postscript. Outlooks Pest Manage. 2005:1–10. doi:10.1564/16aug00.
  • de Waroux YP, Garrett RD, Graesser J, Nolte C, White C, Lambin EF. 2019. The restructuring of South American soy and beef production and trade under changing environmental regulations. World Dev. 121:188–202. doi:10.1016/j.worlddev.2017.05.034.
  • Dill GM, CaJacob CA, Padgette SR. 2008. Glyphosate-resistant crops: adoption, use and future considerations. Pest Manage Sci: formerly Pesticide Sci. 64:326–331. doi:10.1002/ps.1501.
  • Djukanovic V, Smith J, Lowe K, Yang M, Gao H, Jones S, Nicholson MG, West A, Lape J, Bidney D, et al. 2013. Male-sterile maize plants produced by targeted mutagenesis of the cytochrome P450-like gene (MS26) using a re-designed I–CreI homing endonuclease. Plant J. 76:888–899. doi:10.1111/tpj.12335.
  • Dolaychuk OP, Fedoruk RS, Kovalchuk II, Khrabko MI. 2013. Physiological effects of soybeans native and transgenic varieties on the body of the third generation female rats. Animal Biol. 15:22–30. doi:10.15407/animbiol15.03.022.
  • Domingo JL. 2007. Toxicity studies of genetically modified plants: a review of the published literature. Crit Rev Food Sci Nutr. 47:721–733. doi:10.1080/10408390601177670.
  • Domingo JL, Bordonaba JG. 2011. A literature review on the safety assessment of genetically modified plants. Environ Int. 37:734–742.
  • Dong OX, Yu S, Jain R, Zhang N, Duong PQ, Butler C, Li Y, Lipzen A, Martin JA, Barry KW, et al. 2020. Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9. Nat Commun. 11:1–10.
  • Donkin SS, Velez JC, Totten AK, Stanisiewski EP, Hartnell GF. 2003. Effects of feeding silage and grain from glyphosate-tolerant or insect-protected corn hybrids on feed intake, ruminal digestion, and milk production in dairy cattle. J Dairy Sci. 86:1780–1788. doi:10.3168/jds.S0022-0302(03)73763-1.
  • Dorhout DL, Rice ME. 2010. Intraguild competition and enhanced survival of western bean cutworm (Lepidoptera: Noctuidae) on transgenic Cry1Ab (MON810) Bacillus thuringiensis corn. J Econ Entomol. 103:54–62. doi:10.1603/EC09247.
  • Douglas E, Halpin C. 2010. Gene stacking. In: Jain S, Brar D, editors. Molecular techniques in crop improvement. Dordrecht: Springer; p. 613–629. doi:10.1007/978-90-481-2967-6_26.
  • Dowd-Uribe B. 2014. Engineering yields and inequality? How institutions and agro-ecology shape Bt cotton outcomes in Burkina Faso. Geoforum. 53:161–171.
  • Duke SO, Lydon J, Koskinen WC, Moorman TB, Chaney RL, Hammerschmidt R. 2012. Glyphosate effects on plant mineral nutrition, crop rhizosphere microbiota, and plant disease in glyphosate-resistant crops. J Agric Food Chem. 60:10375–10397. doi:10.1021/jf302436u.
  • Duke SO, Powles SB. 2009. Glyphosate resistant crops and weeds: now and in the future. AgBioForum. 12:346–357.
  • Duke SO, Rimando AM, Pace PF, Reddy KN, Smeda RJ. 2003. Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean. J Agric Food Chem. 51:340–4. doi:10.1021/jf025908i.
  • Dunn SE, Vicini JL, Glenn KC, Fleischer DM, Greenhawt MJ. 2017. The allergenicity of genetically modified foods from genetically engineered crops: a narrative and systematic review. Ann Allergy, Asthma & Immunol. 119:214–222. doi:10.1016/j.anai.2017.07.010.
  • Dutton A, Klein H, Romeis J, Bigler K. 2002. Uptake of Bt-toxin by herbivores feeding on transgenic maize and consequences for the predator Chrysoperla carnea. Ecol Entomol. 27:441–447.
  • Edwards HM, Douglas MW, Parsons CM, Baker DH. 2000. Protein and energy evaluation of soybean meals processed from genetically modified high-protein soybeans. Poultry Sci. 79:525–527. doi:10.1093/ps/79.4.525.
  • EFSA GMO Panel Working Group on Animal Feeding Trials. 2008. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials. Food Chem Toxicol. 46(Suppl 1):S2–70. doi:10.1016/j.fct.2008.02.008.
  • EFSA GMO Panel, Andersson HC, Arpaia S, Bartsch D, Casacuberta J, Davies H, du Jardin P, Flachowsky G, Herman L, Jones H, Kärenlampi S, Kiss J, Kleter G, Kuiper H, Messéan A, Nielsen KM, Perry J, Poeting A, Sweet J, Tebbe C, von Wright AJ, Wal J-M. 2010. Scientific Opinion on the assessment of potential impacts of genetically modified plants on non-target organisms. EFSA Journal. 8:1877, p.1–72. doi:10.2903/j.efsa.2010.1877.
  • EFSA GMO Panel, Mullins E, Bresson J-L, Dalmay T, Dewhurst IC, Epstein MM, George Firbank L, Guerche P, Hejatko J, Naegeli H, Nogue F, Rostoks N, Sanchez Serrano JJ, Savoini G, Veromann E, Veronesi F, Fernandez Dumont A, Moreno FJ, et al. 2022a. Scientific opinion on development needs for the allergenicity and protein safety assessment of food and feed products derived from biotechnology. EFSA Journal. 20:7044, p. 1–38. doi:10.2903/j.efsa.2022.7044.
  • EFSA GMO Panel, Mullins E, Bresson J-L, Dalmay T, Dewhurst IC, Epstein MM, George Firbank L, Guerche P, Hejatko J, Naegeli H, Nogue F, Rostoks N, Sanchez Serrano JJ, Savoini G, Veromann E, Veronesi F, Fernandez Dumont A, Moreno FJ, et al. 2022b. Scientific opinion on the assessment of genetically modified oilseed rape MON 94100 for food and feed uses, under regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2020-169). EFSA Journal. 20:Article 7411, 29 pp. doi:10.2903/j.efsa.2022.7411.
  • EFSA GMO Panel, Naegeli H, Birch AN, Casacuberta J, De Schrijver A, Gralak MA, Guerche P, Jones H, Manachini B, Messéan A, Nielsen EE, Nogue F, et al. 2017. Guidance on allergenicity assessment of genetically modified plants. EFSA Journal. 15:e04862. doi:10.2903/j.efsa.2017.4862.
  • EFSA GMO Panel, Naegeli H, Bresson J-L, Dalmay T, Dewhurst IC, Epstein MM, Firbank LG, Guerche P, Hejatko J, Moreno FJ, Mullins E, Nogue F, Rostoks N, Sanchez Serrano JJ, Savoini G, Veromann E, Veronesi F, Fernandez Dumont A. 2021. Statement on in vitro protein digestibility tests in allergenicity and protein safety assessment of genetically modified plants. EFSA Journal 19:6350, p. 1–16. doi:10.2903/j.efsa.2021.6350.
  • Egamberganovich AJ. 2020. Influence of a genetically modified organism on the rat’s hepatobiliary system. Europ J Mol Clin Med. 7:2157–2164.
  • Ehirium BO, Bashir M, Ishaq MN, Gana AS, Salihu BZ, Gbadeyan T, Nwankwo OF, Kouko E, Tolorunse KD, Amedu J, et al. 2020. Genetically modified crops and food security in Nigeria; facts and myths. J Scient Res Rep. 26:54–63.
  • Elferink EV, Nonhebel S, Schoot Uiterkamp AJM. 2007. Does the Amazon suffer from BSE prevention? Agric Ecosyst Environ. 120:467–469. doi:10.1016/j.agee.2006.09.009.
  • Ellstrand NC, Prentice HC, Hancock JF. 1999. Gene flow and introgression from domesticated plants into their wild relatives. Ann Rev.Ecol Syst. 30:539–563. doi:10.1146/annurev.ecolsys.30.1.539.
  • Elmore RW. 2001. Glyphosate-resistant soybean cultivar response to glyphosate. Agron J. 93:404–407. doi:10.2134/agronj2001.932404x.
  • Elmore RW, Roeth FW, Nelson LA, Shapiro CA, Klein RN, Knezevic SZ, Martin A. 2001. Glyphosate-resistant soybean cultivar yields compared with sister lines. Agron J. 93:408–412. doi:10.2134/agronj2001.932408x.
  • El-Mounadi K, Morales-Floriano ML, Garcia-Ruiz H. 2020. Principles, applications, and biosafety of plant genome editing using CRISPR-Cas9. Front Plant Sci. 11:Article 56. doi:10.3389/fpls.2020.00056.
  • Engel J, van der Voet H. 2021. Equivalence tests for safety assessment of genetically modified crops using plant composition data. Food Chem Toxicol. 156:Article 112517. doi:10.1016/j.fct.2021.112517.
  • Ensering M. 2008. Tough lessons from Golden Rice. Science. 320:468–471. doi:10.1126/science.320.5875.468.
  • Erenstein O, Jaleta M, Sonder K, Mottaleb K, Prasanna BM. 2022. Global maize production, consumption and trade: trends and R&D implications. Food Sec. doi:10.1007/s12571-022-01288-7.
  • Ermakova I. 2006. Genetically modified soy leads to the decrease of weight and high mortality of rat pups of the first generation. Preliminary studies. Ecosinform. 1:4–9.
  • Ermakova I. 2009. Influence of soy with gene EPSPS CP4 on the physiological state and reproductive function of rats in the first two generations. Contemp Problems Sci Educ. 5:1520.
  • ETC Group. 2013. Putting the cartel before the horse … and farm, seeds, soil, peasants, etc. who will control agricultural inputs, 2013? Communiqué No. 111. p. 40. https://www.etcgroup.org/sites/www.etcgroup.org/files/CartelBeforeHorse11Sep2013.pdf.
  • Ewen SW, Pusztai A. 1999. Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet. 354:13531354.
  • Ewers RM, Scharlemann JPW, Balmford A, Green RE. 2009. Do increases in agricultural yield spare land for nature? Global Change Biol. 15:1716–1726. doi:10.1111/j.1365-2486.2009.01849.x.
  • Fares NH, El-Sayed AK. 1998. Fine structural changes in the ileum of mice fed on endotoxin treated potatoes and transgenic potatoes. Nat Toxins. 6:219–233. doi:10.1002/(SICI)1522-7189(199811/12)6:6<219::AID-NT30>3.0.CO;2-K.
  • Farre G, Twyman RM, Zhu C, Capell T, Christou P. 2011. Nutritionally enhanced crops and food security: scientific achievements versus political expediency. Curr Opin Biotechnol. 22:245–51. doi:10.1016/j.copbio.2010.11.002.
  • Felke M, Langenbruch G, Feiertag S, Kassa A. 2010. Effect of Bt-176 maize pollen on first instar larvae of the Peacock butterfly (Inachis io) (Lepidoptera; Nymphalidae). Environ Biosafety Res. 9:5–12. doi:10.1051/ebr/2010006.
  • Fernandez-Cornejo J, Hallahan C, Nehring RF, Wechsler S, Grube A. 2012. Conservation tillage, herbicide use, and genetically engineered crops in the United States: the case of soybeans. AgBioForum. 15:231–241. http://hdl.handle.net/10355/35118.
  • Finamore A, Roselli M, Britti S, Monastra G, Ambra R, Turrini A, Mengheri E. 2008. Intestinal and peripheral immune response to MON810 maize ingestion in weaning and old mice. J Agric Food Chem. 56:11533–11539. doi:10.1021/jf802059w.
  • Finger R, El Benni N, Kaphengst T, Evans C, Herbert S, Lehmann B, Morse S, Stupak N. 2011. A meta-analysis on farm-level costs and benefits of GM crops. Sustainability. 3:743–762. doi:10.3390/su3050743.
  • Fister AS, Landherr L, Maximova SN, Guiltinan MJ. 2018. Transient expression of CRISPR/Cas9 machinery targeting TcNPR3 enhances defense response in Theobroma cacao. Front Plant Sci. 9:Article 268. https://www.frontiersin.org/article/10.3389fpls.2018.00268.
  • Flachowsky G. 2017. 20 years commercial cultivation of genetically modified plants (GMP): present stage and challenges from an animal nutrition perspective. Züchtungskunde. 89:91–105.
  • Flachowsky G, Aulrich K, Böhme H, Halle I. 2007. Studies on feeds from genetically modified plants (GMP) – contributions to nutritional and safety assessment. Animal Feed Sci Technol. 133:2–30. doi:10.1016/j.anifeedsci.2006.08.002.
  • Flachowsky G, Chesson A. 2003. Feeds from genetically modified plants in animal nutrition. In: A. Rosati, A. Tewolde, C. Mosconi, editors. WAAP book of the year 2003: a review of livestock systems developments and researches. Wageningen: Wageningen Academic Publishers; p. 241–267.
  • Flachowsky G, Chesson A, Aulrich K. 2005. Animal nutritional with feeds from genetically modified plants. Arch Anim Nutr. 59:1–40.
  • Flachowsky G, Schafft H, Meyer U. 2012. Animal feeding studies for nutritional and safety assessments of feeds from genetically modified plants: a review. J Verbr Lebensm. 7:179–194. doi:10.1007/s00003-012-0777-9.
  • Flavell. 2015. Crop improvement using transgenes, genome editing and microbes: a forward-looking essay to celebrate 20 years of transgenic crops. In: James C, Teng P, Arujanan M, Aldemita RR, Flavell RB, Brookes G, Qaim M, editors. Invitational essays to celebrate the 20th anniversary of the commercialization of biotech crops (1996 to 2015): Progress and Promise. ISAAA Brief 51. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. ISAAA; p. 28–49.
  • Folberth C, Khabarov N, Balkovič J, Skalský R, Visconti P, Ciais P, Janssens IA, Peñuelas J, Obersteiner M. 2020. The global cropland-sparing potential of high-yield farming. Nat Sustain. 3:281–289. doi:10.1038/s41893-020-0505-x.
  • Ford CS, Allainguillaume J, Grilli-Chantler P, Cuccato G, Allender CJ, Wilkinson MJ. 2006. Spontaneous gene flow from rapeseed (Brassica napus) to wild Brassica oleracea. Proc R Soc. B. 273:3111–3115. http://doi.org/10.1098/rspb.2006.3686.
  • Fraiture MA, Roosens NH, Taverniers I, De Loose M, Deforce D, Herman P. 2016. Biotech rice: current developments and future detection challenges in food and feed chain. Trends Food Sci Technol. 52:66–79.
  • Francis L, Craig RK, George E. 2016. FDA’s troubling failures to use its authority to regulate genetically modified foods. Food Drug Law J. 71:105–134. http://www.Biointegrity.org/FDAdoes/17/view1.html.
  • Friedlingstein P, O'Sullivan M, Jones MW, Andrew RM, Hauck J, Olsen A, Peters GP, Peters W, Pongratz J, Sitch S, et al. 2020. Global carbon budget 2020. Earth Syst Sci Data. 12:3269–3340. doi:10.5194/essd-12-3269-2020.
  • Frisvold G, Reeves JM. 2010. Resistance management and sustainable use of agricultural biotechnology. AgBioForum. 13:343–359. http://hdl.handle.net/10355/9967.
  • Frisvold GB, Boor A, Reeves JM. 2009. Simultaneous diffusion of herbicide resistant cotton and conservation tillage. AgBioForum. 12:249–257. http://hdl.handle.net/10355/6931.
  • Frizzi A, Huang S, Gilbertson LA, Armstrong TA, Luethy MH, Malvar TM. 2008. Modifying lysine biosynthesis and catabolism in corn with a single bifunctional expression/silencing transgene cassette. Plant Biotechnol J. 6:13–21. doi:10.1111/j.1467-7652.2007.00290.x.
  • FSANZ. 2021. Food standard Australia New Zealand – current GM applications and approvals. [accessed 2022 April 24]. https://www.foodstandards.govt.nz/consumer/gmfood/applications/Pages/default.aspx#Table1.
  • Fu H, Tan P, Wang R, Li S, Liu H, Yang Y, Wu Z. 2022. Advances in organophosphorus pesticides pollution: current status and challenges in ecotoxicological, sustainable agriculture, and degradation strategies. J Hazard Mat. 424:Article 127494. doi:10.1016/j.jhazmat.2021.127494.
  • Fuchs M, Gonsalves D. 1995. Resistance of transgenic hybrid squash ZW-20 expressing the coat protein genes of zucchini yellow mosaic virus and watermelon mosaic virus 2 to mixed infections by both potyviruses. Nat Biotechnol. 13:1466–1473.
  • Fu-Chun MCF. 2021. Accelerating towards net zero emissions: the most important global health intervention. Lancet Planeta Health. 5:e64–e65.
  • Fukuda-Parr S, Orr A. 2012. GM crops for food security in Africa–the path not yet taken. United Nations Development Programme (UNDP) Working Paper. WP, 18, p. 1–51. [accessed 2022 July 18]. http://sakikofukudaparr.net/wp-content/uploads/2013/01/GMCropsFoodSecAfrica2012.pdf.
  • Galili G, Amir R. 2013. Fortifying plants with the essential amino acids lysine and methionine to improve nutritional quality. Plant Biotechnol J. 11:211–222. doi:10.1111/pbi.12025.
  • Ganguly S, Purohit A, Ghosh S, Chaudhuri RK, Das S, Chakraborti D. 2022. Clean gene technology to develop selectable marker-free pod borer-resistant transgenic pigeon pea events involving the constitutive expression of Cry1Ac. Appl Microbiol Biotechnol. 106:3051–3067. doi:10.1007/s00253-022-11922-1.
  • Gannon B, Kaliwile C, Arscott SA, Schmaelzle S, Chileshe J, Kalungwana N, Mosonda M, Pixley K, Masi C, Tanumihardjo SA. 2014. Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial. Am J Clin Nutr. 100:1541–1550. doi:10.3945/ajcn.114.087379.
  • Garcia MA, Altieri MA. 2005. Transgenic crops: implications for biodiversity and sustainable agriculture. Bull Sci Technol Soc. 25:335–353. doi:10.1177/0270467605277293.
  • Garg M, Sharma N, Sharma S, Kapoor P, Kumar A, Chunduri V, Arora P. 2018. Biofortified crops generated by breeding, agronomy, and transgenic approaches are improving lives of millions of people around the world. Front Nutr. 5:Article 12. doi:10.3389/fnut.2018.00012.
  • Gaskell G, Allum N, Wagner W, Kronberger N, Torgersen H, Hampel J, Bardes J. 2004. GM foods and the misperception of risk perception. Risk Anal. 24:185–194.
  • Gay PB, Gillespie SH. 2005. Antibiotic resistance markers in genetically modified plants; a risk to human health. Lancet Infect Dis. 5:637–646. doi:10.1016/S1473-3099(05)70241-3.
  • Gbashi S, Adebo O, Adebiyi JA, Targuma S, Tebele S, Areo OM, Olopade B, Odukoya JO, Njobeh P. 2021. Food safety, food security and genetically modified organisms in Africa: a current perspective. Biotechnol Gen Eng Rev. 37:30–63. doi:10.1080/02648725.2021.1940735.
  • Gebhard F, Smalla K. 1998. Transformation of Acinetobacter sp. strain BD413 by transgenic sugar beet DNZ. Appl Environ Microbiol. 64:1550–1554.
  • Gebhard F, Smalla K. 1999. Monitoring field releases of genetically modified sugar beets for persistence of transgenic plant DNA and horizontal gene transfer. FEMS Microbiol Ecol. 28:261–272. doi:10.1111/j.1574-6941.1999.tb00581.x.
  • Georges F, Ray H. 2017. Genome editing of crops: a renewed opportunity for food security. GM Crops Food. 8:1–12. doi:10.1080/21645698.2016.1270489.
  • Gepts P, Papa R. 2003. Possible effects of trans(gene) flow from crops to the genetic diversity from landraces and wild relatives. Environ Biosafety Res. 2:89–113. doi:10.1051/ebr:2003009.
  • Ghanizadeh H, Buddenhagen CE, Harrington KC, James TK. 2019. The genetic inheritance of herbicide resistance in weeds. Crit Rev Plant Sci. 38:295–312. doi:10.1080/07352689.2019.1665769.
  • Ghasemi S, Karami E, Azadi H. 2013. Knowledge, attitudes and behavioral intentions of agricultural professionals toward genetically modified (GM) foods: a case study in southwest Iran. Sci Eng Ethics. 19:1201–1227. doi:10.1007/s11948-012-9383-6.
  • Gianessi LP. 2005. Economic and herbicide use impacts of glyphosate-resistant crops. Pest Manag Sci: Formerly Pest Sci. 61:241–245. doi:10.1002/ps.1013.
  • Giannakas K, Yiannaka A. 2008. Market and welfare effects of second-generation, consumer-oriented GM products. Amer J Agric Econ. 90:152–71. doi:10.1111/j.1467-8276.2007.01053.x.
  • Giddings GD, Hamilton NRS, Hayward MD. 1997. The release of genetically modified grasses. 1. Pollen dispersal to traps in Lolium perenne. Theoret Appl Gen. 94:1000–1006.
  • Giraldo P, Shinozuka H, Spangenberg G, Cogan N, Smith K. 2019. Safety assessment of genetically modified feed: is there any difference from food? Front. Plant Sci. 10:Article 1592. doi:10.3389/fpls.2019.01592.
  • Giraudo ME. 2020. Dependent development in South America: China and the soybean nexus. J Agrar Change. 20:60–78. doi:10.1111/joac.12333.
  • Girgi M, Breese WA, Lörz H, Oldach KH. 2006. Rust and downy mildew resistance in pearl millet (Pennisetum glaucum) mediated by heterologous expression of the afp gene from Aspergillus giganteus. Transgenic Res. 15:313–324. doi:10.1007/s11248-006-0001-8.
  • Girish HV, Murali M, Kumar NKH, Singh SB, Jagannath S, Sudarshana MS. 2021. GM crops as a food security solution. In: Singh P, Borthakur A, Singh AA, Kumar A, Singh KK, editors. Policy issues in genetically modified crops. Academic Press; p. 189–199. ISBN 9780128207802, doi:10.1016/B978-0-12-820780-2.00009-1.
  • Givens W, Shaw D, Kruger G, Johnson W, Weller S, Young B, Wilson RG, Owen MD, Jordan D. 2009. Survey of tillage trends following the adoption of glyphosate-resistant crops. Weed Technol. 23:150–155. doi:10.1614/WT-08-038.1.
  • Gizaw Z. 2019. Public health risks related to food safety issues in the food market: a systematic literature review. Environ Health Prev Med. 24:1–21. doi:10.1186/s12199-019-0825-5.
  • Goldstein DA. 2014. Tempest in a tea pot: how did the public conversation on genetically modified crops drift so far from the facts? J Med Toxicol. 10:194–201. doi:10.1007/s13181-014-0402-7.
  • Gonsalves C, Lee DR, Gonsalves D. 2007. The adoption of genetically modified papaya in Hawaii and its implications for developing countries. J Devel Stud. 43:177–191. doi:10.1080/00220380601055650.
  • Gonsalves D. 1998. Control of papaya ringspot virus in papaya: a case study. Ann Rev Phytopathol. 36:415–437.
  • Gonzali S, Mazzucato A, Perata P. 2009. Purple as a tomato: towards high anthocyanin tomatoes. Trends Plant Sci. 14:237–241. doi:10.1016/j.tplants.2009.02.001.
  • Goodman R, Vieths S, Sampson H, Hill D, Ebisawa M, Taylor SL, Van Ree R. 2008. Allergenicity assessment of genetically modified crops – what makes sense? Nat Biotechnol. 26:73–81. doi:10.1038/nbt1343.
  • Gould F, Amasino RM, Brossard D, Buell CR, Dixon RA, Falck-Zepeda JB, Gallo MA, Giller KE, Glenna LL, Griffin T, Magraw D. 2022. Toward product-based regulation of crops. Science. 377:1051–1053. doi:10.1126/science.abo3034.
  • Grafius EJ, Douches DS. 2008. The present and future role of insect-resistant genetically modified potato cultivars in IPM. In: Integration of insect-resistant genetically modified crops within IPM programs, 1st ed. Dordrecht: Springer; p. 195–221.
  • Gray AJ. 2004. Ecology and government policies: the GM crop debate. J Appl Ecol. 41:1–10.
  • Green JM, Owen MD. 2011. Herbicide-resistant crops: utilities and limitations for herbicide-resistant weed management. J Agricult Food Chem. 59:5819–5829. doi:10.1021/jf101286h.
  • Gressel J. 2010. Needs for and environmental risks from transgenic crops in the developing world. New Biotechnol. 27:522–527.
  • Griffin M. 2000. The GM debate. Pesticide Outlook. 11:33–34. https://pubs.rsc.org/en/content/articlepdf/2000/po/b006312f.
  • Griffiths BS, Geoghegan IE, Robertson WM. 2000. Testing genetically engineered potato, producing the lectins GNA and ConA, on nontarget soil organisms and processes. J Appl Ecol. 37:159–170.
  • Grossi-de-Sa MF, Pelegrini PB, Fragoso RR. 2011. Genetically modified soybean for insect-pest and disease control. Soybean-mol Aspects Breed. 4:429–452.
  • Gruère G, Sengupta D. 2011. Bt cotton and farmer suicides in India: an evidence-based assessment. J Dev Stud. 47(2):316–337. http://www.tandfonline.com/doi/abs/10.108000220388.2010.492863.
  • Gruissem W. 2015. Genetically modified crops: the truth unveiled. Agric Food Sec. 4:Article 3. doi:10.1186/s40066-015-0022-8.
  • Guleria P, Kumar V. 2021. GMO to eradicate malnutrition: current status. Current Nutr Food Sci. 17:4–10. doi:10.2174/1573401316999200612112400.
  • Gusta M, Smyth SJ, Belcher K, Phillips PWB, Castle D. 2011. Economic benefits of genetically-modified herbicide-tolerant canola for producers. AgBioForum. 14:1–13. http://hdl.handle.net/10355/10724.
  • Haggblade S, Minten B, Pray C, Reardon T, Zilberman D. 2017. The herbicide revolution in developing countries: patterns, causes, and implications. Europ J Dev Res. 29:533–559. doi:10.1057/s41287-017-0090-7.
  • Halford NG. 2004. Prospects for genetically modified crops. Ann Appl Biol. 145:17–24. doi:10.1111/j.1744-7348.2004.tb00355.x.
  • Halford NG, Shewry PR. 2000. Genetically modified crops: methodology, benefits, regulation and public concerns. Brit Medic Bull. 56:62–73. doi:10.1258/0007142001902978.
  • Halpin C. 2005. Gene stacking in transgenic plants – the challenge for 21st century plant biotechnology. Plant Biotechnol J. 3:141–55. doi:10.1111/j.1467-7652.2004.00113.x.
  • Hammond BG, Dudek R, Lemen JK, Nemeth MA. 2006. Results of a 90-day safety assurance study with rats fed grain from corn borer-protected corn. Food Chem Toxicol. 44:1092–1099.
  • Hammond BG, Vicini JL, Hartnell GF, Naylor MW, Knight CD, Robinson EH, Fuchs RL, Padgette SR. 1996. The feeding value of soybeans fed to rats, chickens, catfish and dairy cattle is not altered by genetic incorporation of glyphosate tolerance. J Nutr. 126:717–727. doi:10.1093/jn/126.3.717.
  • Haughton AJ, Champion GT, Hawes C, Heard MS, Brooks DR, Bohan DA, Clark SJ, Dewar AM, Firbank LG, Osborne JL, et al. 2003. Invertebrate responses to the management of genetically modified herbicide–tolerant and conventional spring crops. ii. Within-field epigeal and aerial arthropods. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 358:1863–1877. doi:10.1098/rstb.2003.1408.
  • Haun W, Coffman A, Clasen BM, Demorest ZL, Lowy A, Ray E, Retterath A, Stoddard T, Juillerat A, Cedrone F, Mathis L. 2014. Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family. Plant Biotechnol J. 12:934–940. doi:10.1111/pbi.12201.
  • Hautea DM, Taylo LD, Masanga APL, Sison MLJ, Narciso JO, Quilloy RB, Hautea RA, Shotkoski FA, Shelton AM. 2016. Field performance of Bt eggplants (Solanum melongena L.) in the Philippines: Cry1Ac expression and control of the eggplant fruit and shoot borer (Leucinodes orbonalis Guenée). PLoS One. 11:e0157498. doi:10.1371/journal.pone.0157498.
  • Haverkort AJ, Struik PC, Visser RGF, Jacobsen E. 2009. Applied biotechnology to combat late Blight in potato caused by Phytophthora infestans. Potato Res. 52:249–264. doi:10.1007/s11540-009-9136-3.
  • Hawkins NJ, Bass C, Dixon A, Neve P. 2019. The evolutionary origins of pesticide resistance. Biol Rev. 94:135–155. doi:10.1111/brv.12440.
  • He XY, Tang MZ, Luo YB, Li X, Cao SS, Yu JJ, Delaney B, Huang KL. 2009. A 90-day toxicology study of transgenic lysine-rich maize grain (Y642) in Sprague–Dawley rats. Food Chem Toxicol. 47:425–432. doi:10.1016/j.fct.2008.11.032.
  • Heap I. 2014. Global perspective of herbicide-resistant weeds. Pest Manag Sci. 70:1306–1315. doi:10.1002/ps.3696.
  • Heard MS, Hawes C, Champion GT, Clark SJ, Firbank LG, Haughton AJ, Parish AM, Perry JN, Rothery P, Roy DB, et al. 2003b. Weeds in fields with contrasting conventional and genetically modified herbicide–tolerant crops. II. Effects on individual species. Phil Trans R Soc Lond. B. 358:1833–1846. http://doi.org/10.1098/rstb.2003.1401.
  • Heard MS, Hawes C, Champion GT, Clark SJ, Firbank LG, Haughton AJ, Parish AM, Perry JN, Rothery P, Scott RJ, et al. 2003a. Weeds in fields with contrasting conventional and genetically modified herbicide–tolerant crops. I. Effects on abundance and diversity. Phil Trans R Soc Lond. B. 358:1819–1832. http://doi.org/10.1098/rstb.2003.1402.
  • Heineman JA. 2009. Hope not hype: the future of agriculture guided by the international assessment of agricultural knowledge, science, and technology for development. Jack Heinemann. Third World Network. Printed by Jutaprint, Penang, Malaysia. [accessed 2022 June 17]. https://www.google.co.nz/books/edition/Hope_Not_Hype/36j5Scwd7oIC?hl=en&gbpv=1&pg=PR5&printsec=frontcover.
  • Heinemann JA, Traavik T. 2004. Problems in monitoring horizontal gene transfer in field trials of transgenic plants. Nat Biotechnol. 22:1105–1109.
  • Hellmich RL, Siegfried BD, Sears MK, Stanley-Horn DE, Daniels MJ, Mattila HR, Spencer T, Bidne KG, Lewis LC. 2001. Monarch larvae sensitivity to Bacillus thuringiensis-purified proteins and pollen. Proc Natl Acad. Sci. 98:11925–11930.
  • Henning C, Witzke P. 2021. Economic and environmental impacts of the green deal on the agricultural economy: a simulation study of the impact of the F2F-strategy on production, trade, welfare and the environment based on the CAPRI-Model. English Summary. https://www.bio-pop.agrarpol.uni-kiel.de/de/f2f-studie/executive-summary-en.
  • Heredia Dıaz O, Aldaba Meza JL, Baltazar BM, Bojórquez Bojórquez G, Castro Espinoza L, Corrales Madrid JL, de la Fuente Martınez JM, Duran Pompa HA, Alonso Escobedo J, Espinoza Banda A, et al. 2017. Plant characterization of genetically modified maize hybrids MON-89Ø34-3 × MON88Ø17-3, MON-89Ø34-3 × MON-ØØ6Ø3-6, and MON-ØØ6Ø3-6: alternatives for maize production in Mexico. Transgenic Res. 26:135–151. doi:10.1007/s11248-016-9991-z.
  • Herman RA, Fast BJ, Scherer PN, Brune AM, de Cerqueira DT, Schafer BW, Ekmay RD, Harrigan GG, Bradfisch GA. 2017. Stacking transgenic event DAS-Ø15Ø7-1 alters maize composition less than traditional breeding. Plant Biotechnol J. 15:1264–1272. doi:10.1111/pbi.12713.
  • Herman RA, Huang E, Fast BJ, Walker C. 2019. EFSA genetically engineered crop composition equivalence approach: performance and consistency. J Agri Food Chem. 67:4080–4088. doi:10.1021/acs.jafc.9b00156.
  • Herman RA, Price WD. 2013. Unintended compositional changes in genetically modified (GM) Crops: 20 years of research. J Agric Food Chem. 61:11695–11701. doi:10.1021/jf400135r.
  • Herman RA, Storer NP, Anderson JA, Amijee F, Cnudde F, Raybould A. 2021. Transparency in risk-disproportionate regulation of modern crop-breeding techniques. GM Crops Food. 12:376–381. doi:10.1080/21645698.2021.1934353.
  • Herman RA, Storer NP, Walker C. 2020. Clarification on “EFSA genetically engineered crop composition equivalence approach: performance and consistency”. J Agric Food Chem. 68:5787–5789. doi:10.1021/acs.jafc.0c01550.
  • Hernández-López E. 2022. Racializing trade in corn: México fights maíz imports and GMOs. J Internat Econ Law. 25:259–276. doi:10.1093/jiel/jgac017.
  • Herring RJ. 2010. Epistemic brokerage in the bio-property narrative: contributions to explaining opposition to transgenic technologies in agriculture. New Biotech. 27:614–622. doi:10.1016/j.nbt.2010.05.017.
  • Hilbeck A, Baumgartner M, Fried PM, Bigler F. 1998. Effects of transgenic Bacillus thuringiensis corn-fed prey on mortality and development time of immature Chrysoperla carnea (Neuroptera: Chrysopidae). Environ Entomol. 27:480–487.
  • Hilbeck A, Meier M, Trtikova M. 2012. Underlying reasons of the controversy over adverse effects of Bt toxins on lady beetle and lacewing larvae. Environ Sci Eur. 24:Article 9. doi:10.1186/2190-4715-24-9.
  • Hilder VA. 2003. GM plants and protection against insects – alternative strategies based on gene technology. Acta Agric Scand. Sect. B Soil Plant Sci. Supplementum. 1:34–40. doi:10.1080/16519140310015076.
  • Hillocks R. 2014. GM crops are an appropriate IPM component technology. Outlooks Pest Manag. 25:217–21. doi:10.1564/v25_jun_07.
  • Ho MW. 2010. Farmer suicides and Bt cotton nightmare unfolding in India. Sci in Soc. 45:32–39. [accessed 2022 June 19]. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.660.3890&rep=rep1&type=pdf.
  • Holme IB, Dionisio G, Brinch-Pedersen H, Wendt T, Madsen CK, Vincze E, Holm PB. 2012. Cisgenic barley with improved phytase activity. Plant Biotechnol J. 10:237–247. doi:10.1111/j.1467-7652.2011.00660.x.
  • Hong J, Yu W, Marinova D, Guo X. 2013. Risk analysis of GM crop technology in China: modelling and governance. Period Biol. 115:307–316. https://hrcak.srce.hr/110645.
  • Horak MJ, Rosenbaum EW, Phillips SL, Kendrick DL, Carson D, Clark PL, Nickson TE. 2015. Characterization of the ecological interactions of Roundup Ready 2 Yield® soybean, MON 89788, for use in ecological risk assessment. GM Crops & Food. 6:167–182. doi:10.1080/21645698.2015.1067365.
  • Howell C. 2008. Consolidated list of environmental weeds in New Zealand. DOC Research & Development Series 292. Wellington: Published by Science & Technical Publishing Department of Conservation. ISBN 978-0-478-14413-0 (web PDF). p. 1–42. [accessed 2022 July 10]. https://www.doc.govt.nz/globalassets/documents/science-and-technical/drds292.pdf.
  • Hu H, Dai M, Yao J, Xiao B, Li X, Zhang Q, Xiong L. 2006. Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice. Proc Natl Acad Sci. 103:12987–12992. https://www.pnas.org/doi/abs/10.1073pnas.0604882103.
  • Huang F. 2011. Resistance to transgenic Bacillus thuringiensis crops in target insect pests: current status and prospect. In: Liu T, Kang L, editors. Recent advances in entomological research. Berlin: Springer; p. 306–329. doi:10.1007/978-3-642-17815-3_18.
  • Huang F, Andow DA, Buschman LL. 2011. Success of the high-dose/refuge resistance management strategy after 15 years of Bt crop use in North America. Entomol Exp Applic. 141:262–278.
  • Huang J, Hu R, Fan C, Pray CE, Rozelle S. 2002. Bt cotton benefits, costs, and impacts in China. AgBioForum. 5:153–166. http://hdl.handle.net/10355/295.
  • Huang J, Hu R, Pray C, Qiao F, Rozelle S. 2003. Biotechnology as an alternative to chemical pesticides: a case study of Bt cotton in China. Agric Econ. 29:55–67. doi:10.1111/j.1574-0862.2003.tb00147.x.
  • Huang J, Hu R, Rozelle S, Pray C. 2005. Development, policy, and impacts of genetically modified crops in China: a comprehensive review of China’s agricultural biotechnology sector. In: Workshop held at Villa Bellagio, Bellagio, Italy, June 2005, p. 1–59. [accessed 2022 June 15]. https://www.belfercenter.org/sites/default/files/files/publication/chinahuangapril06website.pdf.
  • Huang J, Mi J, Lin H, Wang Z, Chen R, Hu R, Rozelle S, Pray C. 2010. A decade of Bt cotton in Chinese fields: assessing the direct effects and indirect externalities of Bt cotton adoption in China. Science China: Life Sci. 53:981–991. https://www.ncbi.nlm.nih.gov/m/pubmed/20821297/.
  • Huang J, Pray C, Rozelle S. 2002. Enhancing the crops to feed the poor. Nature. 418:678–684. doi:10.1038/nature01015.
  • Huang J, Rozelle S, Pray C, Wang Q. 2002. Plant biotechnology in China. Science. 295:674–676.
  • Huang Y, Luo X, Li Z. 2022. Substitution or complementarity: why do rice farmers use a mix of biopesticides and chemical pesticides in China? Pest Manag Sci. 78:1630–1639. doi:10.1002/ps.6781.
  • Hudson D, Richards R. 2014. Evaluation of the agronomic, environmental, economic, and coexistence impacts following the introduction of GM canola to Australia (2008–2010). AgBioForum. 17:1–12. http://hdl.handle.net/10355/43453.
  • Huesing JE, Andres D, Braverman MP, Burns A, Felsot AS, Harrigan GG, Hellmich RL, Reynolds A, Shelton AM, van Rijssen WJ, Morris EJ. 2016. Global adoption of genetically modified (GM) crops: challenges for the public sector. J Agric Food Chem. 64:394–402. doi:10.1021/acs.jafc.5b05116.
  • Hull RO, Bosse MA, Tzotzos GE. 2010. Training for implementing risk assessment regulations for the release of GM crops. Aspects Appl Biol. 96:1–8.
  • Hunt L. 2004. Factors determining the public understanding of GM technologies. AgBiotechNet. 6:1–8.
  • Hussain S, Hussain S, Guo R, Sarwar M, Ren X, Krstic D, Aslam Z, Zulifqar U, Rauf A, Hano C, El-Esawi MA. 2021. Carbon sequestration to avoid soil degradation: a Review on the role of conservation tillage. Plants. 10:Article 2001. doi:10.3390/plants10102001.
  • Hutchison WD, Burkness EC, Mitchell PD, Moon RD, Leslie TW, Fleischer SJ, Abrahamson M, Hamilton KL, Steffey KL, et al. 2010. Areawide suppression of European corn borer with Bt maize reaps savings to non-Bt maize growers. Science. 330:222–225. https://www.ncbi.nlm.nih.gov/pubmed/20929774.
  • Ibarra JG, Colombo RP, Godeas AM, López NI. 2020. Analysis of soil bacterial communities associated with genetically modified drought-tolerant corn. Appl Soil Ecol. 146:Article 103375. doi:10.1016/j.apsoil.2019.103375.
  • Icoz I, Stotzky G. 2008. Fate and effects of insect-resistant Bt crops in soil ecosystems. Soil Biol Biochem. 40:559–586. doi:10.1016/j.soilbio.2007.11.002.
  • ISAAA. 2016. Global status of commercialized biotech/GM crops: 2016. ISAAA Brief No. 52.2017. Ithaca (NY): International Service for the Acquisition of Agri-Biotech Applications. [accessed 2022 June 4]. http://www.isaaa.org/resources/publications/briefs/52/download/isaaa-brief-52-2016.pdf.
  • ISAAA. 2017. Global status of commercialized biotech/GM Crops: ISAAA Brief No. 53. Ithaca (NY): International Service for the Acquisition of Agri-Biotech Applications. [accessed 2022 July 16]. https://www.isaaa.org/resources/publications/briefs/53/default.asp.
  • ISAAA. 2018a. Beyond promises: facts about biotech/GM crops in 2018. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. [accessed 2022 May 22]. https://www.isaaa.org/resources/publications/biotech_booklets/beyondpromises/download/Beyond%20Promises%20Booklet_2018.pdf.
  • ISAAA. 2018b. Global status of commercialized biotech/GM crops: 2018. Biotech crops continue to help meet the challenges of increased population and climate change. ISAAA Brief 54. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. [accessed 2022 May 28]. https://www.isaaa.org/resources/publications/briefs/54/download/isaaa-brief-54-2018.pdf.
  • ISAAA. 2021a. Breaking barriers with breeding: a primer on new breeding innovations for food security. ISAAA Brief 56. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. [accessed 2022 July 16]. https://www.isaaa.org/resources/publications/briefs/56/default.asp.
  • ISAAA. 2021b. ISAAA in 2021. From partnerships to public trust. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. [accessed 2022 May 22]. https://www.isaaa.org/resources/publications/annualreport/2021/pdf/ISAAA-2021-Accomplishment-Report.pdf.
  • ISAAA. 2022. GM approval database – commercial GM traits list. Ithaca (NY): International Service for the Acquisition of Agri-biotech Applications. [accessed 2022 June 22]. https://www.isaaa.org/gmapprovaldatabase/commercialtraitlist/default.asp.
  • Ives AR, Glaum PR, Ziebarth NL, Andow DA. 2011. The evolution of resistance to two-toxin pyramid transgenic crops. Ecologic Applicat. 21:503–515. doi:10.1890/09-1869.1.
  • Jacobsen SE, Sørensen M, Pedersen SM, Weiner J. 2013. Feeding the world: genetically modified crops versus agricultural biodiversity. Agron Sustain Dev. 33:651–662. doi:10.1007/s13593-013-0138-9.
  • Jadhav MS, Rathnasamy SA, Natarajan B, Duraialagaraja S, Varatharajalu U. 2020. Study of Expression of Indigenous Bt cry2AX1 Gene in T3 progeny of cotton and its efficacy against Helicoverpa armigera (Hubner). Braz Arch Biol Technol. 63:1–11. Article e20180428. doi:10.1590/1678-4324-2020180428.
  • James C. 2006. Preview: global status of commercialized biotech/GM crops. ISAAA Brief no. 35. Ithaca (NY): ISAAA.
  • James C. 2010. A global overview of biotech (GM) crops: adoption, impact and future prospects. GM Crops. 1:8–12. doi:10.4161/gmcr.1.1.9756.
  • James C. 2011. Global status of commercialized biotech/GM crops. Ithaca, NY: ISAAA. Volume 44.
  • James C. 2015. Executive summary: 20th anniversary of the global commercialization of biotech crops (1996 to 2015) and biotech crop highlights in 2015. In: James C, Teng P, Arujanan M, Aldemita RR, Flavell RB, Brookes G, Qaim M, editors. 20th anniversary of the global commercialization of biotech crops (1996 to 2015) and biotech crop highlights in 2015. International Service for the Acquisition of Agri-Biotech Applications (ISAAA) Brief 51. Ithaca (NY): ISAAA; p. 1–16.
  • James C. 2016. Global status of commercialized biotech/GM crops: 2016. ISAAA Brief No. 52. Ithaca (NY): International Service for the Acquisition of Agri-Biotech Applications.
  • Janušauskaite D, Kadžienė G, Auškalnienė O. 2013. The effect of tillage system on soil microbiota in relation to soil structure. Pol J Environ Stud. 22:1387–1391. http://www.pjoes.com/pdf-89103-22962?filename=The%20Effect%20of%20Tillage.pdf.
  • Jarrell ZR, Ahammad MU, Benson AP. 2020. Glyphosate-based herbicide formulations and reproductive toxicity in animals. Vet Animal Sci. 10:Article.100126. doi:10.1016/j.vas.2020.100126.
  • Jiang M, Liu Y, Liu Y, Tan Y, Huang J, Shu Q. 2019. Mutation of Inositol 1,3,4-trisphosphate 5/6-kinase6 impairs plant growth and phytic acid synthesis in rice. Plants. 8:Article 114. doi:10.3390/plants8050114.
  • Jiao Z, Si XX, Li GK, Zhang ZM, Xu XP. 2010. Unintended compositional changes in transgenic rice seeds (Oryza sativa L.) studied by spectral and chromatographic analysis coupled with chemometrics methods. J Agric Food Chem. 58:1746–1754. doi:10.1021/jf902676y.
  • Jin Y, Drabik D. 2022. CRISPR Rice vs conventional rice dilemma of a Chinese farmer. Aust J Agric Resour Econ. 66:424–446. doi:10.1111/1467-8489.12465.
  • Jin Y, Drabik D, Heerink N, Wesseler J. 2019. The cost of postponement of Bt rice commercialization in China. Front Plant Sci. 10:1226. doi:10.3389/fpls.2019.01226.
  • Jolly C, Jefferson-Moore K, Traxler G. 2005. Consequences of biotechnology policy for competitiveness and trade of southern U.S. agriculture. J Agric Appl Econ. 37:393–407. doi:10.1017/S1074070800006866.
  • Jones H. 2015. GM foods: is there a way forward? Proc Nutr Soc. 74:198–201. doi:10.1017/S002966511500209.
  • Jones PJ, Tranter RB. 2014. Farmers’ interest in growing GM crops in the UK, in the context of a range of on-farm coexistence issues. AgBioForum. 17:13–21. http://www.agbioforum.org/v17n1/v17n1a02-tranter.h.
  • Jose M, Vertuan H, Soares D, Sordi D, Bellini LF, Kotsubo R, Berger GU. 2020. Comparing agronomic and phenotypic plant characteristics between single and stacked events in soybean, maize, and cotton. PLoS One. 15:e0231733. doi:10.1371/journal.pone.0231733.
  • Jung JH, Fouad WM, Vermerris W, Gallo M, Altpeter F. 2012. RNAi suppression of lignin biosynthesis in sugarcane reduces recalcitrance for biofuel production from lignocellulosic biomass. Plant Biotechnol J. 10:1067–1076. doi:10.1111/j.1467-7652.2012.00734.x.
  • Kadoić Balaško M, Mikac KM, Bažok R, Lemic D. 2020. Modern techniques in Colorado Potato Beetle (Leptinotarsa decemlineata Say) control and resistance management: history review and future perspectives. Insects. 11:Article 581. doi:10.3390/insects11090581.
  • Kalaitzandonakes N, Phillips PW, Wesseler J, Smyth SJ. 2016. The coexistence of genetically modified, organic and conventional foods – government policies and market practices. New York (NY): Springer Science+ Business Media. p. 425. ISBN: 978-1-4939-3727-1. doi:10.1007/978-1-4939-3727-1.
  • Kamle M, Kumar P, Patra JK, Bajpai VK. 2017. Current perspectives on genetically modified crops and detection methods. Biotech. 7:Article 219. doi:10.1007/s13205-017-0809-3.
  • Kanchiswamy CN, Sargent DJ, Velasco R, Maffei ME, Malnoy M. 2015. Looking forward to genetically edited fruit crops. Trends Biotechnol. 33:62–64. doi:10.1016/j.tibtech.2014.07.003.
  • Kangmennaang J, Osei L, Armah FA, Luginaah I. 2016. Genetically modified organisms and the age of (un) reason? A critical examination of the rhetoric in the GMO public policy debates in Ghana. Futures. 83:37–49. doi:10.1016/j.futures.2016.03.002.
  • Kannan P, Parameswari C, Prasanyaselvam K, Sridevi G, Veluthambi K. 2017. Introgression of sheath blight disease tolerance from the transgenic rice event Pusa Basmati1-CG27 to the variety White Ponni through backcross breeding. Ind J Genet Plant Breed. 77:501–507. doi:10.5958/0975-6906.2017.00066.9.
  • Kapur M, Bhatia R, Pandey G, Pandey J, Paul D, Jain RK. 2010. . A case study for assessment of microbial community dynamics in genetically modified Bt cotton crop fields. Curr Microbiol. 61:118–124. doi:10.1007/s00284-010-9585-6.
  • Karavolias NG, Horner W, Abugu MN, Evanega SN. 2021. Application of gene editing for climate change in agriculture. Front. Sustain. Food Syst. 5:Article 685801. doi:10.3389/fsufs.2021.685801.
  • Kareiva P, Morris W, Jacobi CM. 1994. Studying and managing the risk of cross-fertilization between transgenic crops and wild relatives. Mol Ecol. 3:15–21. doi:10.1111/j.1365-294X.1994.tb00037.x.
  • Karlsson ME, Leeman AM, Björck IM, Eliasson AC. 2007. Some physical and nutritional characteristics of genetically modified potatoes varying in amylose/amylopectin ratios. Food Chem. 100:136–146. doi:10.1016/j.foodchem.2005.09.032.
  • Kathage J, Qaim M. 2012. Economic impacts and impact dynamics of Bt (Bacillus thuringiensis) cotton in India. Proc Natl Acad Sci U.S.A. 109:11652–11656. doi:10.1073/pnas.1203647109.
  • Katoch R. 2022. Biotechnological techniques for nutritional quality improvement in forages. In: Nutritional quality management of forages in the Himalayan region. Singapore: Springer; p. 465–492. doi:10.1007/978-981-16-5437-4_15.
  • Kaur N, Alok A, Kumar P, Kaura N, Awasthia P, Chaturvedi S, Pandeya P, Pandeya S, Pandeya AK, Tiwariet S. 2020. CRISPR/Cas9 directed editing of lycopene epsilon-cyclase modulates metabolic flux for β-carotene biosynthesis in banana fruit. Metab Eng. 59:76–86.
  • Kavi Kishor PB, Rajam MV, Pullaiah T. 2021. Genetic tinkering of crops for sustainable development: 2020 and beyond. In: Kavi Kishor PB, Rajam MV, Pullaiah T, editors. Genetically modified crops. Singapore: Springer. doi:10.1007/978-981-15-5897-9_1.
  • Kebede GG. 2020. Development of resistance to Bacillus thuringiensis (Bt) toxin by insect pests. Asian J Res Biosci. 2:9–28. https://www.globalpresshub.com/index.php/AJORIB/article/view/840.
  • Keeling PJ, Palmer JD. 2008. Horizontal gene transfer in eukaryotic evolution. Nat Rev Genet. 9:605–618.
  • Keese P. 2008. Risks from GMOs due to horizontal gene transfer. Environ Biosafety Res. 7:123–149.
  • Kendall HW, Beachy R, Eisner T, Gould F, Herdt R, Raven PH, Schell JS, Swaminathan MS. 1997. Bioengineering of crops: report of the World Bank Panel on transgenic crops. Environmental and Socially Sustainable Development Studies and Monograph Series 23. p. 30. ISBN-13:978-0821340738.
  • Kennedy GG. 2008. Integration of insect-resistant genetically modified crops within IPM programs. In: Romeis J, Shelton AM, Kennedy GG, editors. Progress in biological control 5. Dordrecht: Springer; p. 1–26. ISBN 978-1-4020-8372-3.
  • Kessler DA, Taylor MR, Maryanski JH, Flamm EL, Kahl LS. 1992. The safety of foods developed by biotechnology. Science. 256:1747–1749. doi:10.1126/science.1615315.
  • Key S, Ma JK, Drake PM. 2008. Genetically modified plants and human health. J R Soc Med. 101:290–8. doi:10.1258/jrsm.2008.070372.
  • Khush GS. 2012. Genetically modified crops: the fastest adopted crop technology in the history of modern agriculture. Agric Food Sec. 1:14. http://www.agricultureandfoodsecurity.com/content/1/1/14.
  • Kikulwe EM, Birol E, Wesseler J, Falck-Zepeda J. 2011. A latent class approach to investigating demand for genetically modified banana in Uganda. Agric Econ. 42:547–560. doi:10.1111/j.1574-0862.2010.00529.x.
  • Kilic A, Akay MT. 2008. A three generation study with genetically modified Bt corn in rats: biochemical and histopathological investigation. Food Chem Toxicol. 46:1164–1170.
  • Kim DY, Eom MS, Kim HJ, Ko EM, Pack IS, Park JH, Park KW, Nam KH, Oh SD, Kim JK, Seo JS. 2020. Gene flow from transgenic soybean, developed to obtain recombinant proteins for use in the skin care industry, to non-transgenic soybean. Appl Biol Chem. 63:Article 65. doi:10.1186/s13765-020-00550-w.
  • Kim KM, Ryu TH, Suh SJ. 2010. Studies on insect diversity related to genetically engineered vitamin A rice under large scale production. Korean J Breed Sci. 42:157–162.
  • Kim SI, Tai TH. 2014. Identification of novel rice low phytic acid mutations via TILLING by sequencing. Mol Breeding. 34:1717–1729. doi:10.1007/s11032-014-0127-y.
  • Kisiangani E, Pasteur K. 2008. Why the GM route won’t feed a hungry Africa. Paper presented at the Feeding the World Conference, p. 1–12. https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.521.2484&rep=rep1&type=pdf.
  • Klümper W, Qaim M. 2014. A meta-analysis of the impacts of genetically modified crops. PLoS One. 9:e111629. http://dx.plos.org/10.1371journal.pone.0111629.
  • Kok EJ, Keijer J, Kleter GA, Kuiper HA. 2008. Comparative safety assessment of plant-derived foods. Reg Toxicol Pharmacol. 50:98–113. doi:10.1016/j.yrtph.2007.09.007.
  • Konig A, Cockburn A, Crevel RWR, Debruyne E, Grafstroem R, Hammerling U, Kimber I, Knudsen I, Kuipe HA, Peijnenburg AACM, et al. 2004. Assessment of the safety of foods derived from genetically modified (GM) crops. Food Chem Toxicol. 42:1047–1088. doi:10.1016/j.fct.2004.02.019.
  • Kos M, van Loon JJ, Dicke M, Vet LE. 2009. Transgenic plants as vital components of integrated pest management. Trends Biotechnol. 27:621–627. doi:10.1016/j.tibtech.2009.08.002.
  • Kotey DA, Assefa Y, Obi A, van den Berg J. 2016. Disseminating genetically modified (GM) maize technology to smallholder farmers in the Eastern Cape province of South Africa: extension personnel’s awareness of stewardship requirements and dissemination practices. Sth Afr J Agric Ext. 44:59–74. doi:10.17159/2413-3221/2016/v44n1a370.
  • Kouser S, Qaim M. 2011. Impact of Bt cotton on pesticide poisoning in smallholder agriculture: a panel data analysis. Ecol Econ. 70:2105–2113. http://www.sciencedirect.com/science/article/pii/S0921800911002400.
  • Kovach J, Petzoldt C, Degni J, Tette J. 1992. A method to measure the environmental impact of pesticides. New York’s Food and Life Sciences Bulletin. 139:1–8. [accessed 2022 May 28]. https://ecommons.cornell.edu/handle/1813/55750.
  • Kramer MG, Redenbaugh K. 1994. Commercialization of a tomato with an antisense polygalacturonase gene: the FLAVR SAVR™ tomato story. Euphytica. 79:293–297. doi:10.1007/BF00022530.
  • Kramkowska M, Grzelak T, Czyzewska K. 2013. Benefits and risks associated with genetically modified food products. Ann Agric Environ Med. 20:413–419. https://pubmed.ncbi.nlm.nih.gov/24069841/.
  • Kranthi KR, Stone GD. 2020. Long-term impacts of Bt cotton in India. Nat Plants. 6:188–196. doi:10.1038/s41477-020-0615-5.
  • Krattiger A. 2010. Intellectual property, commercial needs and humanitarian benefits: must there be a conflict? New Biotechnol. 27:573–577.
  • Kruger M, Van Rensburg JBJ, Van den Berg J. 2012. Transgenic Bt maize: farmers’ perceptions, refuge compliance and reports of stem borer resistance in South Africa. J Appl Entomol. 136:38–50. doi:10.1111/j.1439-0418.2011.01616.x.
  • Kubisz P, Dalton G, Majewski E, Pogodzinska K. 2021. Facts and myths about GM food – the case of Poland. Agriculture. 11:Article 791. doi:10.3390/agriculture11080791.
  • Kumar A, Jaiswal P, Janeja HS. 2022. Chapter 8. Biosafety aspects of genetically modified crops. Genetically modified plants and beyond. In: Niang IS, editor. Genetically modified plant and beyond. London: IntechOpen; p. 145–162.
  • Kumar K, Gambhir G, Dass A, Tripathi AK, Singh A, Jha AK, Yadava P, Choudhary M, Rakshit S. 2020. Genetically modified crops: current status and future prospects. Planta. 251:Article 91. doi:10.1007/s00425-020-03372-8.
  • Kumari C, Sharma M, Kumar V, Sharma R, Kumar V, Sharma P, Kumar P, Irfan M. 2022. Genome editing technology for genetic amelioration of fruits and vegetables for alleviating post-harvest loss. Bioengineering. 9:Article 176. doi:10.3390/bioengineering9040176.
  • Kuosmanen T, Pemsl D, Wesseler J. 2006. Specification and estimation of production functions involving damage control inputs: a two-stage, semiparametric approach. Amer J Agric Econ. 88:499–511. doi:10.1111/j.1467-8276.2006.00874.x.
  • Kuzma J, Kokotovich A. 2011. Renegotiating GM crop regulation: targeted gene-modification technology raises new issues for the oversight of genetically modified crops. EMBO Reports. 12:883–888. doi:10.1038/embor.2011.160.
  • Lack G. 2002. Clinical risk assessment of GM foods. Toxicol Letters. 127:337–340.
  • Ladics GS. 2008. Current codex guidelines for assessment of potential protein allergenicity. Food Chem Toxicol. 46:S20–S23. doi:10.1016/j.fct.2008.07.021.
  • Ladics GS. 2019. Assessment of the potential allergenicity of genetically-engineered food crops. J Immunotoxicol. 16:43–53. doi:10.1080/1547691X.2018.1533904.
  • Ladics GS, Bartholomaeus A, Bregitzer P, Doerrer NG, Gray A, Holzhauser T, Jordan M, Keese P, Kok E, Macdonald P, Parrott W. 2015. Genetic basis and detection of unintended effects in genetically modified crop plants. Transgenic Res. 24:587–603. doi:10.1007/s11248-015-9867-7.
  • Lal S, Gulyani V, Khurana P. 2008. Overexpression of HVA1 gene from barley generates tolerance to salinity and water stress in transgenic mulberry (Morus indica). Transgenic Res. 17:651–663. doi:10.1007/s11248-007-9145-4.
  • Lappé M, Bailey B, Childress C, Setchell KDR. 1999. Alterations in clinically important phytoestrogens in genetically modified herbicide tolerant soybean. J Med Food. 1:241–245. doi:10.1089/jmf.1998.1.241.
  • Lassoued R, Macall DM, Smyth SJ, Phillips PW, Hesseln H. 2020. How should we regulate products of new breeding techniques? Opinion of surveyed experts in plant biotechnology. Biotechnol Rep. 26:e00460. doi:10.1016/j.btre.2020.e00460.
  • Lawo NC, Wäckers FL, Romeis J. 2009. Indian Bt cotton varieties do not affect the performance of cotton aphids. PLoS One. 4:e4804. doi:10.1371/journal.pone.0004804.
  • Lee S, Clay DE, Clay SA. 2014. Impact of herbicide tolerant crops on soil health and sustainable agriculture crop production. In: Songstad D, Hatfield J, Tomes D, editors. Convergence of food security, energy security and sustainable agriculture. Biotechnology in Agriculture and Forestry 67. Berlin: Springer; p. 211–236. doi:10.1007/978-3-642-55262-5_10.
  • Légère A. 2005. Risks and consequences of gene flow from herbicide-resistant crops: canola (Brassica napus L) as a case study. Pest Manag Sci. 61:292–300. doi:10.1002/ps.975.
  • Leguizamón A. 2014. Modifying Argentina: GM soy and socio-environmental change. Geoforum. 53:149–160. doi:10.1016/j.geoforum.2013.04.001.
  • Lehrer SB, Bannon GA. 2005. Risks of allergic reactions to biotech proteins in foods: perception and reality. Allergy. 60:559–564.
  • Lehtinen S, Chewapreecha C, Lees J, Hanage WP, Lipsitch M, Croucher NJ, Bentley SD, Turner P, Fraser C, Mostowy RJ. 2020. Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae. Sci Adv. 6:eaaz6137. doi:10.1002/evl3.226.
  • Levidow L. 2012. EU regulatory conflicts over GM food: lessons for the future. In: Thompson PB, Kaplan DM, editors. Encyclopedia of food and agricultural ethics. Dordrecht: Springer Science+Business Media; p. 1–8. doi:10.1007/978-94-007-6167-4_359-2.
  • Levidow L, Boschert K. 2008. Coexistence or contradiction? GM crops versus alternative agricultures in Europe. Geoforum. 39:174–190. doi:10.1016/j.geoforum.2007.01.001.
  • Levidow L, Carr S. 2007. GM crops on trial: technological development as a real-world experiment. Futures. 39:408–431. http://technology.open.ac.uk/cts/bpg.
  • Li J, Scarano A, Gonzalez NM, D’Orso  F, Yue Y, Nemeth K, Saalbach G, Hill L, de Oliveira Martins C, Moran R, et al. 2022. Biofortified tomatoes provide a new route to vitamin D sufficiency. Nat Plants. 8:611–616. doi:10.1038/s41477-022-01154-6.
  • Li Y, Gao Y, Wu K. 2017. Function and effectiveness of natural refuge in IRM strategies for Bt crops. Curr Opin Insect Sci. 21:1–6. doi:10.1016/j.cois.2017.04.007.
  • Li Y, Hallerman EM, Liu Q, Wu K, Peng Y. 2016. The development and status of Bt rice in China. Plant Biotechnol J. 14:839–848. doi:10.1111/pbi.12464.
  • Li Z, Feng J, Zhou M, Zhang M, Chang Y. 2015. Effects of feeding transgenic rice containing Cry1Ab/1Ac gene on growth and development in two generations of quails. Chin J Anim Nutr. 27:2168–75.
  • Liu H, Hu H, Tang K, Rehman M, Du G, Huang Y, Liu F. 2022. Overexpressing hemp salt stress induced transcription factor genes enhances tobacco salt tolerance. Indust Crops Prod. 117:Article 114497. doi:10.1016/j.indcrop.2021.114497.
  • Liu R-R, Zhao G-P, Zheng M-Q, Liu J, Zhang J-J, Li P, Li Q-H, Feng J-H, Zhang M-H, Wen J. 2016. Effect of feeding transgenic cry1Ab/cry1Ac rice on indices of immune function in broilers. J Integr Agric. 15:1355–1363. doi:10.1016/S2095-3119(15)61281-3.
  • Liu W, Lu HH, Wu W, Wei QK, Chen YX, Thies JE. 2008. Transgenic Bt rice does not affect enzyme activities and microbial composition in the rhizosphere during crop development. Soil Biol Biochem. 40:475–486. doi:10.1016/j.soilbio.2007.09.017.
  • Liu Y, Luo Z, Zhao Y, Xiao N. 2020. The selective feeding of cotton bollworms (Helicoverpa armigera) on transgenic and non-transgenic cotton leaves from consecutive cultivation fields. Int J Pest Manag. 66:195–200. doi:10.1080/09670874.2019.1603412 .
  • Liu Y, Stewart CN. 2019. An exposure pathway-based risk assessment system for GM plants. Plant Biotechnol J. 17:1859–1861. doi:10.1111/pbi.13146.
  • Lius S, Manshardt RM, Fitch MMM, Slightom JL, Sanford JC, Gonsalves D. 1997. Pathogen-derived resistance provides Papaya with effective protection against Papaya Ringspot Virus. Mol Breed. 3:161–168.
  • Livermore M, Turner R. 2009. GM soybean cropping in the USA – a review. Outlooks Pest Manag. 20:135–136. https://docserver.ingentaconnect.com/deliver/connect/resinf/17431026/v20n3/s12.pdf?expires=1655411944&id=0000&titleid=75002301&checksum=BAA8945B20A80F2E5477728481C54B57&host=https://www.ingentaconnect.com.
  • Lohani N, Singh MB, Bhalla PL. 2022. Biological parts for engineering abiotic stress tolerance in plants. BioDesign Res. 2022:Article 9819314. doi:10.34133/2022/9819314.
  • Lombardo L, Trenti M, Zelasco S. 2020. GM crops: resistance development and impact on biodiversity. In: Chaurasia A, Hawksworth DL, Pessoa de Miranda M, editors. GMOs – implications for biodiversity, conservation and ecological processes. Cham: Springer; p. 35–68. doi:10.1007/978-3-030-53183-6_3.
  • Losey JE, Rayor LS, Carter ME. 1999. Transgenic pollen harms monarch larvae. Nature. 399:214.
  • Loza C, Reinsch T, Loges R, Taube F, Gere JI, Kluß C, Hasler M, Malisch CS. 2021. Methane emission and milk production from jersey cows grazing perennial ryegrass – white clover and multispecies forage mixtures. Agriculture. 11:175. doi:10.3390/agriculture11020175.
  • Lu BR. 2008. Transgene escape from GM crops and potential biosafety consequences: an environmental perspective. Collect Biosaf Rev. 4:66–141.
  • Lu BR, Snow AA. 2005. Gene flow from genetically modified rice and its environmental consequences. BioScience. 55:669–678. doi:10.1641/0006-3568(2005)055[0669:GFFGMR]2.0.CO;2.
  • Lu H, Wu W, Chen Y, Zhang X, Devare M, Theis JE. 2010a. Decomposition of Bt transgenic rice residues and response of soil microbial community in rapeseed – rice cropping system. Plant Soil. 336:279–290. doi:10.1007/s11104-010-0476-1.
  • Lu HP, Luo T, Fu HW, Wang L, Tan YY, Huang JZ, Wang Q, Ye GY, Gatehouse AM, Lou YG, Shu QY. 2018. Resistance of rice to insect pests mediated by suppression of serotonin biosynthesis. Nat Plants. 4:338–344. doi:10.1038/s41477-018-0152-7.
  • Lu Y, Wu K, Jiang Y, Guo Y, Desneux N. 2012. Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services. Nature. 487:362–367.
  • Lu Y, Wu K, Jiang Y, Xia B, Li P, Feng H, Wyckhuys KA, Guo Y. 2010b. Mirid bug outbreaks in multiple crops correlated with wide-scale adoption of Bt cotton in China. Science. 328:1151–1154. https://www.science.org/doi/abs/10.1126science.1187881.
  • Lucas DM, Taylor ML, Hartnell GF, Nemeth MA, Glenn KC, Davis SW. 2007. Broiler performance and carcass characteristics when fed diets containing lysine maize (LY038 or LY038 × MON 810), control, or conventional reference maize. Poultry Sci. 86:2152–2161. doi:10.1093/ps/86.10.2152.
  • Lucht. 2015. Public acceptance of plant biotechnology and GM crops. Viruses. 7:4254–4281. doi:10.3390/v7082819.
  • Ludvikova M, Griga M. 2015. Transgenic flax/linseed (Linum usitatissimum L.) – expectations and reality. Czech J Genet Plant Breed. 51:123–141. doi:10.17221/104/2015-CJGPB.
  • Luna JK, Dowd-Uribe B. 2020. Knowledge politics and the Bt cotton success narrative in Burkina Faso. World Dev. 136:Article 105127. doi:10.1016/j.worlddev.2020.105127.
  • Lundgren JG, Huber A, Wiedenmann RN. 2005. Quantification of consumption of corn pollen by the predator Coleomegilla maculata (Coleoptera: Coccinellidae) during anthesis in an Illinois cornfield. Agr Forest Entomol. 7:53–60. doi:10.1111/j.1461-9555.2005.00246.x.
  • Ma BL, Subedi KD. 2005. Development, yield, grain moisture and nitrogen uptake of Bt corn hybrids and their conventional near-isolines. Field Crops Res. 93:199–211. doi:10.1016/j.fcr.2004.09.021.
  • Ma J, Tang X, Sun B, Wei J, Ma L, Yuan M, Zhang D, Shao Y, Li C, Chen K-M, Jiang L. 2022. A NAC transcription factor, TaNAC5D-2, acts as a positive regulator of drought tolerance through regulating water loss in wheat (Triticum aestivum L.). Environ Experiment Bot. 196:Article 104805. doi:10.1016/j.envexpbot.2022.104805.
  • Mabubu JI, Nawaz M, Hua H. 2016. Advances of transgenic Bt-crops in insect pest management: an overview. J Entomol Zool Stud. 4:48–52.
  • Machado EP, dos S Rodrigues Junior GL, Führ FM, Zago SL, Marques LH, Santos AC, Nowatzki T, Dahmer ML, Omoto C, Bernardi O. 2020. Cross-crop resistance of Spodoptera frugiperda selected on Bt maize to genetically-modified soybean expressing Cry1Ac andCry1F proteins in Brazil. Sci Rep. 10:1–9. doi:10.1038/s41598-020-67339-1.
  • MacKenzie SA, Lamb I, Schmidt J, Deege L, Morrisey MJ, Harper M, Layton RJ, Prochaska LM, Sanders C, Locke M, et al. 2007. Thirteen week feeding study with transgenic maize grain containing event DAS-Ø15Ø7-1 in Sprague–Dawley rats. Food & Chem Toxicol. 45:551–562. doi:10.1016/j.fct.2006.09.016.
  • Macnaghten P. 2015. Comparing GM Crops in Mexico, Brazil and India. In: Macnaghten P, Carro-Ripalda S, editors. Governing agricultural sustainability. London: Routledge; p. 131–146. doi:10.4324/9781315709468.
  • Magana-Gomez JA, Calderon de la Barca AM. 2009. Risk assessment of genetically modified crops for nutrition and health. Nutr Rev. 67:1–16. doi:10.1111/j.1753-4887.2008.00130.x.
  • Maino JL, Umina PA, Hoffmann AA. 2018. Climate contributes to the evolution of pesticide resistance. Global Ecol Biogeogr. 27:223–232. doi:10.1111/geb.12692.
  • Makhotenko AV, Khromov AV, Snigir EA, Makarova SS, Makarov VV, Suprunova TP, Kalinina NO, Taliansky ME. 2019. Functional analysis of coilin in virus resistance and stress tolerance of potato Solanum tuberosum using CRISPR-Cas9 editing. Doklady Biochem Biophys. 484:88–91. doi:10.1134/S1607672919010241.
  • Malatesta M, Biggiogera M, Manuali E, Rocchi MBL, Baldelli B, Gazzanelli G. 2003. Fine structural analyses of pancreatic acinar cell nuclei from mice fed on genetically modified soybean. Eur J Histochem. 47:385–388.
  • Malatesta M, Boraldi F, Annovi G, Baldelli B, Battistelli S, Biggiogera M, Quaglino D. 2008. A long term study on female mice fed on a genetically modified soybean: effects on liver ageing. Histochem Cell Biol. 130:967–977.
  • Malatesta M, Caporaloni C, Gavaudan S, Rocchi MB, Serafini S, Tiberi C, Gazzanelli G. 2002. Ultrastructural morphometrical and immunocytochemical analyses of hepatocyte nuclei from mice fed on genetically modified soybean. Cell Struct Funct. 27:173–180.
  • Mall T, Han L, Tagliani L, Christensen C. 2018. Transgenic crops: status, potential, and challenges. In: Gosal S, Wani S, editors. Biotechnologies of crop improvement 2. Cham: Springer; p. 451–485. doi:10.1007/978-3-319-90650-8_16.
  • Mallesh M, Sravanthy C. 2021. Seasonal diversity and abundance of predatory arthropods (insect predators and spiders) in Bt and non-Bt cotton fields. Uttar Pradesh J Zoo. 42:29–37.
  • Malone LA, Burgess EPJ. 2009. Impact of genetically modified crops on pollinators. In: Ferry N, Gatehouse AMR, editors. Environmental impact of genetically modified crops. Cambridge: CABI International; p. 199–224.
  • Mampuys R, Brom FW. 2015. Governance strategies for responding to alarming studies on the safety of GM crops. J Respon Innovat. 2:201–219. doi:10.1080/23299460.2015.1057797.
  • Mandal A, Sarkar B, Owens G, Thakur JK, Manna MC, Niazi NK, Jayaraman S, Patra AK. 2020. Impact of genetically modified crops on rhizosphere microorganisms and processes: a review focusing on Bt cotton. Appl Soil Ecol. 148:Article 103492. doi:10.1016/j.apsoil.2019.103492.
  • Mannion AM, Morse S. 2013. GM crops 1996–2012: a review of agronomic, environmental and socio-economic impacts. University of Surrey, Centre for Environmental Strategy Working Paper 4: 1–40. https://www.surrey.ac.uk/sites/default/files/2018-03/04-13-morse-mannion-GM-crops.pdf.
  • Marques LH, Santos AC, Castro BA, Storer NP, Babcock JM, Lepping MD, Sa V, Moscardini VF, Rule DM, Fernandes OA. 2018. Impact of transgenic soybean expressing Cry1Ac and Cry1F proteins on the non-target arthropod community associated with soybean in Brazil. PLoS One. 13:Article e0191567. doi:10.1371/journal.pone.0191567.
  • Marra M, Piggott N. 2006. The value of non-pecuniary characteristics of crop biotechnologies: a new look at the evidence. In: Just RE, Alston JM, editors. Regulating agricultural biotechnology: economics and policy, natural resource management and policy 30. New York (NY): Springer; p. 145–178.
  • Marra MC, Piggott NE, Carlson GA. 2004. The net benefits, including convenience of roundup ready soybeans: results from a national survey. NSF Center for IPM Technical Bulletin 3. Raleigh, NC, p. 39.
  • Marris C. 2015. The construction of imaginaries of the public as a threat to synthetic biology. Sci Cult. 24:83–98. doi:10.1080/09505431.2014.986320.
  • Marshall A. 2007. Re-examined the work of Ermakova – Marshall, A. GM soybeans and health safety – a controversy reexamined. Nat Biotechnol. 25:981–987. doi:10.1038/nbt0907-981.
  • Martineau B. 2001. First fruit. The creation of the flavr tomato and the birth of biotech foods. New York: MC Graw-Hill Press. 269 pp.
  • Marvier M, McCreedy C, Regetz J, Kareiva P. 2007. A meta-analysis of effects of Bt cotton and maize on nontarget invertebrates. Science. 316:1475–1477. doi:10.1126/science.1139208.
  • Mazza R, Soave M, Morlacchini M, Piva G, Marocco A. 2005. Assessing the transfer of genetically modified DNA from feed to animal tissues. Trans Res. 14:775–784.
  • Mbabazi R, Koch M, Maredia K, Guenthner J. 2021. Crop biotechnology and product stewardship. GM Crops Food. 12:106–114. doi:10.1080/21645698.2020.1822133.
  • Mbaya H, Lillico S, Kemp S, Simm G, Raybould A. 2022. Regulatory frameworks can facilitate or hinder the potential for genome editing to contribute to sustainable agricultural development. Front Bioeng Biotechnol. 10:Article 959236. doi:10.3389/fbioe.2022.959236.
  • McBride W, El-Osta H. 2002. Impacts of the adoption of genetically engineered crops on farm financial performance. J Agric Appl Econ. 34:175–191. doi:10.1017/S1074070800002224.
  • McGloughlin MN. 2010. Modifying agricultural crops for improved nutrition. New Biotechnol. 27:494–504.
  • McHughen A. 2000. The regulation of GM foods: who represents the public interest? Internatl J. 55:624–632. doi:10.1177/002070200005500406.
  • McNaughton SJ. 1993. Biodiversity and function of grazing systems. In: Schulze ED, Mooney HA, editors. Biodiversity and ecosystem function. Berlin: Springer; p. 361–383.
  • Means NE, Kremer RJ. 2007. Influence of soil moisture on root colonization of glyphosate-treated soybean by Fusarium species. Commun Soil Sci Plant Anal. 38:1713–1720. doi:10.1080/00103620701435472.
  • Medina-Lozano I, Díaz A. 2022. Applications of genomic tools in plant breeding: crop biofortification. Int J Mol Sci. 23:Article 3086. doi:10.3390/ijms23063086.
  • Meftaul IM, Venkateswarlu K, Dharmarajan R, Annamalai P, Asaduzzaman M, Parven A, Megharaj M. 2020. Controversies over human health and ecological impacts of glyphosate: is it to be banned in modern agriculture? Environ Poll. 263:Article 114372. doi:10.1016/j.envpol.2020.114372.
  • Mehboob-ur-Rahman, Shaheen T, Irem S, Zafar Y. 2015. Biosafety risk of genetically modified crops containing cry genes. In: Lichtfouse E, Schwarzbauer J, Robert D, editor. CO2 sequestration, biofuels and depollution. Environmental Chemistry for a Sustainable World 5. Cham: Springer International Publishing; p. 307–334. doi:10.1007/978-3-319-11906-9_8.
  • Mehta D. 2019. Highlight negative results to improve science. Nature Careers Community. doi:10.1038/d41586-019-02960-3.
  • Mehta D, Stürchler A, Anjanappa RB, Zaidi SS, Hirsch-Hoffmann M, Gruissem W, Vanderschuren H. 2019. Linking CRISPR-Cas9 interference in cassava to the evolution of editing-resistant geminiviruses. Genome Biol. 20:Article 80. doi:10.1186/s13059-019-1678-3.
  • Mehta D, Vanderschuren H. 2021. Towards responsible communication of agricultural biotechnology research for the common good. Nature Reviews Molecular Cell Biol. 22:301–302. doi:10.1038/s41580-021-00343-z.
  • Mehta R, Cassol T, Li N, Ali N, Handa AK, Mattoo AK. 2002. Engineered polyamine accumulation in tomato enhances phytonutrient content, juice quality, and vine life. Nat Biotechnol. 20:613–618. doi:10.1038/nbt0602-613.
  • Meier MS, Hilbeck A. 2001. Influence of transgenic Bacillus thuringiensis corn-fed prey on prey preference of immature Chrysoperla carnea (Neuroptera: Chrysopidae). Basic Appl Ecol. 2:35–44.
  • Meissle M, Naranjo SE, Romeis J. 2022. Database of non-target invertebrates recorded in field experiments of genetically engineered Bt maize and corresponding non-Bt maize. BMC Res Notes. 15:Article 199. https://bmcresnotes.biomedcentral.com/track/pdf/10.1186s13104-022-06021-3.pdf.
  • Mesnage R, Antoniou MN. 2017. Facts and fallacies in the debate on glyphosate toxicity. Front Pub Health. 5:Article 316. doi:10.3389/fpubh.2017.00316.
  • Messean A, Angevin F, Gómez-Barbero M, Menrad K, Rodríguez-Cerezo E, editors. 2006. New case studies on the coexistence of GM and non-GM crops in European agriculture. Brussells: European Commission. p. 1–116. ISBN:9279012312.
  • Miller JD. 2008. Mycotoxins in small grains and maize: old problems, new challenges. Food Addit Contam: Part A. 25:219–230. doi:10.1080/02652030701744520.
  • Millstone E, Brunner E, Mayer S. 1999. Beyond ‘substantial equivalence’. Nature. 401:525–526. doi:10.1038/44006.
  • Monjardino M, Pannell DJ, Powles SB. 2005. The economic value of glyphosate-resistant canola in the management of two widespread crop weeds in a Western Australian farming system. Agricult Syst. 84:297–315. doi:10.1016/j.agsy.2004.06.018.
  • Morandini P. 2010. Inactivation of allergens and toxins. New Biotechnol. 27:482–493.
  • Mortensen DA, Egan JF, Maxwell BD, Ryan MR, Smith RG. 2012. Navigating a critical juncture for sustainable weed management. BioScience. 62:75–84. doi:10.1525/bio.2012.62.1.12.
  • Moschini GC. 2015. In medio stat virtus: coexistence policies for GM and non-GM production in spatial equilibrium. Eur Rev Agric Econ. 42:851–874. doi:10.1093/erae/jbu040.
  • Moscona J, Sastry KA. 2022. Inappropriate technology: evidence from global agriculture. Available at SSRN 3886019. p. 1–94. [accessed 2022 June 18]. https://ssrn.com/abstract=3886019 or doi:10.2139/ssrn.3886019.
  • Motta R. 2016. Global capitalism and the nation state in the struggles over GM crops in Brazil. J Agrarian Change. 16:720–727. doi:10.1111/joac.12165.
  • MPI. 2019. Operational code. Protocol for testing for the presence of genetically modified plant material. p. 1–22. [accessed 2022 June 18]. https://www.mpi.govt.nz/dmsdocument/10250-Protocol-for-Testing-for-the-Presence-of-Genetically-Modified-Plant-Material-Plant-Import-Requirement.
  • MPI. 2020. National pest plant accord. [2022 accessed July 10]. https://www.mpi.govt.nz/dmsdocument/3664-National-Pest-Plant-Accord-manual-Reprinted-in-February-2020-minor-amendments-only.
  • MPI. 2021. Labelling requirements for genetically modified food. [accessed 2022 June 18]. https://www.mpi.govt.nz/food-business/labelling-composition-food-drinks/specific-product-labelling/labelling-requirements-for-genetically-modified-food/.
  • Muhammad W, Javed K, Javed H, Ahmad M, Khan MA. 2020. The impact of transgenic Brinjal for the control of Leucinodes orbonalis guenee and possible effects on non-target arthropods: a comprehensive review. Plant Protect. 4:131–5. doi:10.33804/pp.004.03.3420.
  • Mühl M. 2020. Insect-resistant genetically modified crops: regulation framework and current situation in Argentina. Outlooks Pest Manag. 31:14–23.
  • Mumpuys R, Brom FWA. 2015. Ethics of dissent: a plea for restraint in the scientific debate about the safety of GM crops. J Agric Environ Ethics. 28:903–924. doi:10.1007/s10806-015-9564-9.
  • Munkvold GP, Hellmich RL, Rice LR. 1999. Comparison of fumonisin concentrations in kernels of transgenic Bt maize hybrids and nontransgenic hybrids. Plant Dis. 83:130–138.
  • Munkvold GP, Hellmich RL, Showers WB. 1997. Reduced Fusarium ear rot and symptomless infection in kernels of maize genetically engineered for European corn borer resistance. Phytopathol. 87:1071–1077.
  • Murrell F. 2011. Confusion, coercion and collusion: why we are eating GM food. Chain Reaction #113 December 2011. p. 19–21. [accessed 2022 July 23]. https://search.informit.org/doi/10.3316informit.989070675285997.
  • Muzhinji N, Ntuli V. 2020. Genetically modified organisms and food security in Southern Africa: conundrum and discourse. GM Crops Food. 12:25–35. doi:10.1080/21645698.2020.1794489.
  • Nalluri N, Karri VR. 2020. Recent advances in genetic manipulation of crops: a promising approach to address the global food and industrial applications. Plant Sci. Today. 7:70–92. doi:10.14719/pst.2020.7.1.659.
  • Namanya P, Tindamanyire J, Buah S, Namaganda J, Kubiriba J, Tushemereirwe W. 2020. Genetically modified bananas for communities of the great lakes region of Africa. In: Anderson V, editor. Genetically modified and irradiated food. Academic Press; p. 117–130. ISBN 9780128172407. doi:10.1016/B978-0-12-817240-7.00007-3.
  • Napier JA, Haslam RP, Tsalavouta M, Sayanova O. 2019a. The challenges of delivering genetically modified crops with nutritional enhancement traits. Nat Plants. 5:563–567. doi:10.1038/s41477-019-0430-z.
  • Napier JA, Olsen RE, Tocher DR. 2019b. Update on GM canola crops as novel sources of omega-3 fish oils. Plant Biotechnol J. 17:703–705.
  • Naranjo SE, Ruberson JR, Sharma HC, Wilson L, Wu K. 2008. The present and future role of insect-resistant genetically modified cotton in IPM. In: Romeis J, Shelton AM, Kennedy GG, editors. Integration of insect-resistant genetically modified crops within IPM programs. Progress in Biological Control 5. Dordrecht: Springer; p. 159–194. ISBN 978-1-4020-8372-3.
  • NASEM. 2016. Genetically engineered crops: experiences and prospects. Washington, DC: National Academies Press. doi:10.17226/23395.
  • Neilsen KM, van Elsas JD, Smalla K. 2000. Transformation of Acinetobacter sp. strain BD413 (pFG4deltanptII) with transgenic plant DNA in soil microcosms and effects of kanamycin on selection of transformants. Appl Environ Microbiol. 66:1237–1242.
  • Nerlich B, Dingwall R, Martin P. 2004. Genetic and genomic discourses at the dawn of the 21st Century. Discourse Soc. 15:363–368. doi:10.1177/0957926504043704.
  • Netherwood T, Martin-Orue SM, O’Donnell AG, Gockling S, Graham J, Mathers JC, Gilbert HJ. 2004. Assessing the survival of transgenic plant DNA in the human gastrointestinal tract. Nat Biotechnol. 22:204–209. doi:10.1038/nbt934.
  • Newell-McGloughlin M. 2008. Nutritionally improved agricultural crops. Plant Physiol. 147:939–953. doi:10.1104/pp.108.121947.
  • Nicolia A, Manzo A, Veronesi F, Rosellini D. 2014. An overview of the last 10 years of genetically engineered crop safety research. Crit Rev Biotechnol. 34:77–88. https://pubmed.ncbi.nlm.nih.gov/24041244/.
  • Niraula PM, Fondong VN. 2021. Development and adoption of genetically engineered plants for virus resistance: advances, opportunities and challenges. Plants. 10:2339. doi:10.3390/plants10112339.
  • Niu L, Liu F, Zhang S, Luo J, Zhang L, Ji J, Gao X, Ma W, Cui J. 2020. Transgenic insect-resistant Bt cotton expressing Cry1Ac/CpTI does not affect the mirid bug Apolygus lucorum – another serious pest of cotton in China. Environ Poll. 264:Article 114762. doi:10.1016/j.envpol.2020.114762.
  • Noleppa S, Cartsburg M. 2021. The socio-economic and environmental values of plant breeding in the EU and for selected EU member states. An ex-post evaluation and ex-ante assessment considering the “Farm to Fork” and “Biodiversity” strategies. Berlin: HFFA Research GmbH. p. 327.
  • Nordic Working Group. 1991. Nordic working group on food toxicology and risk assessment 1991. Food and new biotechnology – novelty, safety and control aspects of foods made by new biotechnology. NORD (Series) 18. Copenhagen: Nordic Council of Ministers.
  • Nordlee JA, Taylor SL, Townsend JA, Thomas LA, Bush RK. 1996. Identification of a Brazil-nut allergen in transgenic soybeans. N Engl J Med. 334:688–692.
  • Novotny E. 2022. Glyphosate, roundup and the failures of regulatory assessment. Toxics. 10:Article 321. doi:10.3390/toxics10060321.
  • Nwosu OK, Ubaoji KI. 2020. Genetic modification as a control mechanism to plant pest attack. In: Egbuna C, Sawicka B, editors. Natural remedies for pest, disease and weed control. Academic Press; p. 203–208. doi:10.1016/B978-0-12-819304-4.00017-8.
  • Oberhauser KS, Prysby MD, Mattila HR, Stanley-Horn DE, Sears MK, Dively G, Olson E, Pleasants JM, Lam W-KF, Hellmich RL. 2001. Temporal and spatial overlap between monarch larvae and corn pollen. Proc Natl Acad Sci. 98:11913–11918.
  • O'Callaghan M, Glare TR, Burgess EP, Malone LA. 2005. Effects of plants genetically modified for insect resistance on nontarget organisms. Ann Rev Entomol. 50:271–92.
  • OECD. 1993. Safety evaluation of foods derived by modern biotechnology. Paris: OECD. 77 pp. [accessed 2022 June 6]. http://www.oecd.org/dataoecd/37/18/41036698.pdf.
  • OECD. 1998. Test No. 408: repeated dose 90-day oral toxicity study in rodents. In: OECD guidelines for the testing of chemicals, Section, 4, health effects. Paris: OECD. [accessed 2022 June 6]. https://www.oecd-ilibrary.org/docserver/9789264070707-en.pdf?expires=1654508260&id=id&accname=guest&checksum=05CFAC4B1B5D0517CAF3B24EDFCCC20F.
  • OECD. 2016. Farm management practices to foster green growth. OECD Green Growth Studies. Paris: OECD Publishing. p. 160. doi:10.1787/9789264238657-en.
  • Ogwu MC. 2021. Lifelong consumption of plant-based GM foods: is it safe? In: Khosrow-Pour M, editor-in-chief. Research anthology on food waste reduction and alternative diets for food and nutrition security. p. 1168–1186. https://www.igi-global.com/chapter/lifelong-consumption-of-plant-based-gm-foods/268193.
  • Oh SD, Park SY, Lee SK, Yun DW, Lee GS, Suh SJ. 2020. Influence of vitamin A-enhanced transgenic soybean cultivation on the diversity of insects in LMO quarantine fields. Korean Soc Breed Sci. 52:310–321. doi:10.9787/KJBS.2020.52.4.310.
  • Okeno JA, Wolt JD, Misra MK, Rodriguez L. 2013. Africa's inevitable walk to genetically modified (GM) crops: opportunities and challenges for commercialization. New Biotechnol. 30:124–130. doi:10.1016/j.nbt.2012.09.001.
  • Okuzaki A, Ogawa T, Koizuka C, Kanekoa K, Inabaa M, Imamuraa J, Koizuka N. 2018. CRISPR/Cas9-mediated genome editing of the fatty acid desaturase 2 gene in Brassica napus. Plant Physiol Biochem. 131:63–69.
  • Oliva R, Ji C, Atienza-Grande G, Huguet-Tapia JC, Perez-Quintero A, Li T, Eom JS, Li C, Nguyen H, Liu B, et al. 2019. Broad-spectrum resistance to bacterial blight in rice using genome editing. Nat Biotechnol. 37:1344–1350. doi:10.1038/s41587-019-0267-z.
  • Oluwambe TM, Oludaunsi SA. 2017. Agricultural biotechnology, the solution to food crisis in Nigeria. Adv Plants Agric Res. 6:Article 00219. doi:10.15406/apar.2017.06.0021.
  • Origin Agritech. 2010. Origin Agritech announces final approval of world’s first GM phytase corn. Outlooks on Pest Management – Biotechnol News. 21:22. doi:10.1564/21feb06.
  • Ortman EE, Barry BD, Buschman LL, Calvin DW, Carpenter J, Dively GP, Foster JE, Fuller BW, Helmich RL, Higgins RA, et al. 2001. Transgenic insecticidal corn: the agronomic and ecological rationale for its use. BioScience. 51:900–903. doi:10.1641/0006-3568(2001)051[0900:TICTAA]2.0.CO;2.
  • Ostry V, Ovesna J, Skarkova J, Pouchova V, Ruprich J. 2010. A review on comparative data concerning Fusarium mycotoxins in Bt maize and non-Bt isogenic maize. Mycotox Res. 26:141–145. doi:10.1007/s12550-010-0056-5.
  • Paarlberg R. 2009. Starved for science: how biotechnology is being kept out of Africa. Harvard: Harvard University Press. p. 93. ISBN-13:978-0-674-02973-6.
  • Paine JA, Shipton CA, Chaggar S, Howells RM, Kennedy MJ, Vernon G, Wright SY, Hinchliffe E, Adams JL, Silverstone AL, Drake R. 2005. Improving the nutritional value of Golden Rice through increased pro-vitamin A content. Nat Biotechnol. 23:482–7.
  • Panchin AY, Tuzhikov AI. 2017. Published GMO studies find no evidence of harm when corrected for multiple comparisons. Crit Rev Biotechnol. 37:213–217. doi:10.3109/07388551.2015.1130684.
  • Pandian S, Ramesh M. 2020. Chapter 1. Development of pesticide resistance in pests. In: Srivastava PK, Singh VP, Singh A, Tripathi DK, Singh S, Prasad SM, Chauhan DK, editor. Pesticides in crop production. doi:10.1002/9781119432241.ch1.
  • Parisi C, Rodríguez-Cerezo E. 2021. Current and future market applications of new genomic techniques. EUR 30589 EN. Luxembourg: Publications Office of the European Union. p. 52, JRC123830. doi:10.2760/02472.
  • Parisi C, Tillie P, Rodríguez-Cerezo E. 2016. The global pipeline of GM crops out to 2020. Nature Biotechnol. 34:31–36.
  • Parrot W. 2010. Genetically modified myths and realities. New Biotechnol. 27:545–551.
  • Passioura JB. 2020. Translational research in agriculture. Can we do it better? Crop Past Sci. 71:517–528. doi:10.1071/CP20066.
  • Pearson H. 2006. Transgenic cotton drives insect boom. Nature. 25:1. doi:10.1038/news060724-5.
  • Pellegrino E, Bedini S, Nuti M, Ercoli L. 2018. Impact of genetically engineered maize on agronomic, environmental and toxicological traits: a meta-analysis of 21 years of field data. Sci Rep. 8:Article 3113. doi:10.1038/s41598-018-21284-2.
  • Peng A, Chen S, Lei T, Xu L, He Y, Wu L, Yao L, Zou X. 2017. Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus. Plant Biotechnol J. 15:1509–1519. http://onlinelibrary.wiley.com/doi/10.1111pbi.12733/full.
  • Pepoyan AZ, Chikindas ML. 2020. Plant-associated and soil microbiota composition as a novel criterion for the environmental risk assessment of genetically modified plants. GM Crops Food. 11:47–53. doi:10.1080/21645698.2019.1703447.
  • Perera DN, Hewavitharana GG, Navaratne SB. 2021. Comprehensive study on the acrylamide content of high thermally processed foods. BioMed Res Internatl. 2021:Article 6258508. doi:10.1155/2021/6258508.
  • Phalan B, Green RE, Dicks LV, Dotta G, Feniuk C, Lamb A, Strassburg BBN, Williams DR, zu Ermgassen EKHJ, Balmford A. 2016. How can higher-yield farming help to spare nature? Science. 351:450–451. https://www.science.org/doi/10.1126science.aad0055.
  • Phélinas P, Choumert J. 2017. Is GM soybean cultivation in Argentina sustainable? World Dev. 99:452–462. doi:10.1016/j.worlddev.2017.05.033.
  • Phillipson M, Smyth SJ. 2016. Regulatory lags for genetically modified crops: legal and political perspectives. In: Kalaitzandonakes N, Phillips P, Wesseler J, Smyth S, editors. The coexistence of genetically modified, organic and conventional foods. Natural Resource Management and Policy, Vol. 49. New York (NY): Springer; doi:10.1007/978-1-4939-3727-1_17.
  • Phipps RH, Jones AK, Tingey AP, Abeyasekera S. 2005. Effect of corn silage from an herbicide-tolerant genetically modified variety on milk production and absence of transgenic DNA in milk. J Dairy Sci. 88:2870–2878. doi:10.3168/jds.S0022-0302(05)72968-4.
  • Pilson D, Prendeville HR. 2004. Ecological effects of transgenic crops and the escape of transgenes into wild populations. Ann Rev Ecol Evol Systemat. 35:149–174. http://www.jstor.org/stable/30034113.
  • Pimentel D. 2005. Environmental and economic costs of the application of pesticides primarily in the United States. Environ Dev Sust. 7:229–252.
  • Pleasants JM, Hellmich RL, Dively GP, Sears MK, Stanley-Horn DE, Mattila HR, Foster JE, Clark P, Jones GD. 2001. Corn pollen deposition on milkweeds in and near cornfields. Proc Natl Acad Sci. 98:11919–11924.
  • Podevin N, du Jardin P. 2012. Possible consequences of the overlap between the CaMV 35S promoter regions in plant transformation vectors used and the viral gene VI in transgenic plants. GM Crops Food. 3:296–300. doi:10.4161/gmcr.21406.
  • Pontiroli A, Simonet P, Frostegard A, Vogel TM, Monier JM. 2007. Fate of transgenic plant DNA in the environment. Environ Biosafety Res. 6:15–35.
  • Poppy GM. 2004. Geneflow from GM plants – towards a more quantitative risk assessment. Trends Biotechnol. 22:436–438.
  • Portier CJ, Armstrong BK, Baguley BC, Baur X, Belyaev I, Bellé R, Belpoggi F, Biggeri A, Bosland MC, Bruzzi P, et al. 2016. Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). J Epidemiol Community Health. 70:741–745. doi:10.1136/jech-2015-207005.
  • Potrykus I. 2010. Lessons from the ‘Humanitarian Golden Rice’ project: regulation prevents development of public good genetically engineered crop products. New Biotechnol. 27:466–472.
  • Prabha D, Negi YK, Chauhan JS. 2020. Genetically modified crops and transgene introgression: towards a solution. In: Singh Y, editor. Recent trends in molecular biology and biotechnology 1. New Delhi: Integrated Publications; p. 97–114.
  • Prado JR, Segers G, Voelker T, Carson D, Dobert R, Phillips J, Cook K, Cornejo C, Monken J, Grapes L, Reynolds T. 2014. Genetically engineered crops: from idea to product. Ann Rev Plant Biol. 65:769–790. doi:10.1146/annurev-arplant-050213-040039.
  • Prakash D, Verma S, Bhatia R, Tiwary BN. 2011. Risks and precautions of genetically modified organisms. Int Sch Res Notices. 211:1–14.
  • Pray C, Ma D, Huang J, Qiao F. 2001. Impact of Bt cotton in China. World Dev. 30(6):931–948. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.318.5539&rep=rep1&type=pdf.
  • Preeti KP. 2022. Engineering chickpea variety HC-1 with OsRuvB gene for salt stress tolerance. Legume Research – An Internatl J. 45:168–173. doi:10.18805/LR-4317.
  • Prescott VE, Campbell PM, Moore A, Mattes J, Rothenberg ME, Foster PS, Higgins TJ, Hogan SP. 2005. Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. J Agric Food Chem. 53:9023–9030.
  • Pretty JN, Morison JI, Hine RE. 2003. Reducing food poverty by increasing agricultural sustainability in developing countries. Agric Ecosystems Environ. 95:217–234.
  • Purchase IFH. 2005. What determines the acceptability of genetically modified food that can improve human nutrition? Toxicol Appl Pharmacol. 207:S19–S27. doi:10.1016/j.taap.2004.12.025.
  • Purnhagen K, Wesseler J. 2021. EU regulation of new plant breeding technologies and their possible economic implications for the EU and beyond. Appl Econ Perspect Policy. 43:1621–1637. doi:10.1002/aepp.13084.
  • Purnhagen KP, Clemens S, Eriksson D, Fresco LO, Tosun J, Qaim M, Visser RG, Weber AP, Wesseler JH, Zilberman D. 2021. Europe’s farm to fork strategy and its commitment to biotechnology and organic farming: conflicting or complementary goals? Trends Plant Sci. 26:600–606. doi:10.1016/j.tplants.2021.03.012.
  • Pusztai A. 2001. Genetically modified foods: are they a risk to human/animal health? Action Bioscience [accessed 2022 July 9] https://www.globalmagazine.info/sites/default/files/PDF/pusztai-gm-foods-risk-human-animal-health-2001.pdf.
  • Pusztai A. 2002. Can science give us the tools for recognizing possible health risk of GM? Nutr Health. 16:73–84. doi:10.1177/026010600201600202.
  • Qaim M. 2005. Agricultural biotechnology adoption in developing countries. American J Agric Econ. 87:1317–1324.
  • Qaim M. 2009. The economics of genetically modified crops. Ann Rev Resource Econ. 1:665–694.
  • Qaim M. 2010. Benefits of genetically modified crops for the poor: household income, nutrition, and health. New Biotechnol. 27:552–557.
  • Qaim M. 2015. Global impact of GM crops, 1996–2015. In: Clive James C, Teng P, Arujanan M, Aldemita RR, Flavell RB, Brookes G, Qaim M, editors. Invitational essays to celebrate the 20th anniversary of the commercialization of biotech crops (1996 to 2015): progress and promise. ISAAA Brief 51. Ithaca (NY): ISAAA; p. 54–56. ISBN 978-1-892456-65-6.
  • Qaim M, De Janvry A. 2005. Bt cotton and pesticide use in Argentina: economic and environmental effects. Environ Dev Econ. 10:179–200. doi:10.1017/S1355770X04001883.
  • Qaim M, Traxler G. 2005. Roundup ready soybeans in Argentina: farm level and aggregate welfare effects. Agric Econ. 32:73–86. doi:10.1111/j.0169-5150.2005.00006.x.
  • Qaim M, Zilberman D. 2003. Yield effects of genetically modified crops in developing countries. Science. 299:900–902.
  • Qiao F. 2015. Fifteen years of Bt cotton in China: the economic impact and its dynamics. World Dev. 70:177–185. doi:10.1016/j.worlddev.2015.01.011.
  • Qiao F, Huang J. 2020. Sustainability of the economic benefit of Bt cotton in China: results from household surveys. J Dev Stud. 56:2045–2060. doi:10.1080/00220388.2019.1640872.
  • Qiu J. 2010. GM crop use makes minor pests major problem. Nature. doi:10.1038/news.2010.242.
  • Racheal N, Park JR, Jeon DW, Kim KM. 2020. A comparison between the agricultural traits of GM and non-GM rice in drought stress and non-stress conditions. J Life Sci. 30:411–9. doi:10.5352/JLS.2020.30.5.411.
  • Rahman M, Zaman M, Shaheen T, Irem S, Zafar Y. 2015. Safe use of cry genes in genetically modified crops. Environ Chem Lett. 13:239–249. doi:10.1007/s10311-015-0508-4.
  • Rahman SU, McCoy E, Raza G, Ali Z, Mansoor S, Amin I. 2022. Improvement of soybean; a way forward transition from genetic engineering to new plant breeding technologies. Mol Biotechnol. doi:10.1007/s12033-022-00456-6.
  • Rahnama H, Nikmard M, Abolhasani M, Osfoori R, Sanjarian F, Habashi AA. 2017. Immune analysis of cry1Ab-genetically modified potato by in-silico analysis and animal model. Food Sci Biotechnol. 26:1437–1445. doi:10.1007/s10068-017-0181-4.
  • Raj RS, Singh C, Modi A, Subhash N. 2015. Genetic transformation of lowland rice variety GR11 for drought tolerance and its ratification for upland paddy cultivation. Ind J Gen Plant Breed. 75:30–40. doi:10.5958/0975-6906.2015.00003.6.
  • Raman R. 2017. The impact of genetically modified (GM) crops in modern agriculture: a review. GM Crops Food. 8:195–208. doi:10.1080/21645698.2017.1413522.
  • Ramesh S, Nagadhara D, Reddy VD, Rao KV. 2004. Production of transgenic indica rice resistant to yellow stem borer and sap-sucking insects, using super-binary vectors of Agrobacterium tumefaciens. Plant Sci. 166:1077–1085. doi:10.1016/j.plantsci.2003.12.028.
  • Ramessar K, Capell T, Twyman RM, Christou P. 2010. Going to ridiculous lengths – European coexistence regulations for GM crops. Nat Biotechnol. 28:133–136. doi:10.1038/nbt0210-133.
  • Raney T. 2006. Economic impact of transgenic crops in developing countries. Curr Opin Biotechnol. 17:174–178. doi:10.1016/j.copbio.2006.02.009.
  • Rani NS, Prasad GSV, Subba Rao LV, Sudharshan I, Pandey MK, Babu VR, Ram T, Padmavathi G, Muralidharan K, Pasalu IC, Viraktamath BC. 2008. High yielding rice varieties of India Technical bulletin No. 33. Hyderabad: Directorate of Rice Research; p. 1–188.
  • Ranum P, Peña-Rosas JP, Garcia-Casal MN. 2014. Global maize production, utilization, and consumption. Ann NY Acad Sci. 1312:105–112. doi:10.1111/nyas.12396.
  • Raps A, Kehr J, Gugerli P, Moar WJ, Bigler F, Hilbeck A. 2001. Immunological analysis of phloem sap of Bacillus thuringiensis corn and of the nontarget herbivore Rhopalosiphum padi (Homoptera: Aphididae) for the presence of Cry1Ab. Mol Ecol. 10:525–533. doi:10.1046/j.1365-294x.2001.01236.x.
  • Rasool S, Rasool T, Gani KM. 2022. A review of interactions of pesticides within various interfaces of intrinsic and organic residue amended soil environment. Chem Eng J Adv. 11:Article 100301. doi:10.1016/j.ceja.2022.100301.
  • Raven PH. 2010. Does the use of transgenic plants diminish or promote biodiversity? New Biotechnol. 27:528–533.
  • Raven PH. 2014. GM crops, the environment and sustainable food production. Transgenic Res. 23:915–921. doi:10.1007/s11248-013-9756-x.
  • Ravindran V, Tabe LM, Molvig L, Higgins T, Bryden WL. 2002. Nutritional evaluation of transgenic high-methionine lupins (Lupinus angustifolius L) with broiler chickens. J Sci Food Agric. 82:280–285. doi:10.1002/jsfa.1030.
  • Ravisankar D, Chinnusamy C, Nithya C. 2017. Weed management in herbicide tolerant transgenic maize – a review. Chem Sci Rev Lett. 6:2364–2372.
  • Ray D, Ramankutty N, Mueller N, West PC, Foley JA. 2012. Recent patterns of crop yield growth and stagnation. Nat Commun. 3:Article 1293. doi:10.1038/ncomms2296.
  • Raybould A. 2021. Improving the politics of biotechnological innovations in food security and other sustainable development goals. Transgenic Res. 30:613–618. doi:10.1007/s11248-021-00277-4.
  • Raybould A, Graser G, Hill K, Ward K. 2012. Ecological risk assessments for transgenic crops with combined insect-resistance traits: the example of Bt11 × MIR604 maize. J Appl Entomol. 136:27–37. doi:10.1111/j.1439-0418.2010.01601.x.
  • Reddy KN, Nandula VK. 2012. Herbicide resistant crops: history, development and current technologies. Indian J Agron. 57:1–7.
  • Reddy PB, Gujetiya RK, Bhatnagar P. 2013. GM technology can solve the world food crisis. Sci Secure J Biotech. 2:36–40.
  • Reichman JR, Watrud LS, Lee EH, Burdick CA, Bollman MA, Storm MJ, King GA, Mallory-Smith C. 2006. Establishment of transgenic herbicide-resistant creeping bentgrass (Agrostis stolonifera L.) in non-agronomic habitats. Molecular Ecology. 15:4243–4255. doi:10.1111/j.1365-294X.2006.03072.x.
  • Reiss MJ. 2001. Ethical considerations at the various stages in the development, production, and consumption of GM crops. J Agric Environ Ethics. 14:179–190.
  • Rezbova H, Skubna O. 2012. The role of transgenic crops in the future of global food and feed. Agris On-Line Papers in Econ Inform. 4:49–59.
  • Rezende-Teixeira P, Dusi RG, Jimenez PC, Espindola LS, Costa-Lotufo LV. 2022. What can we learn from commercial insecticides? Efficacy, toxicity, environmental impacts, and future developments. Environ Pollution. 300:Article 118983. doi:10.1016/j.envpol.2022.118983.
  • Ridley WP, Harrigan GG, Breeze ML, Nemeth MA, Sidhu RS, Glenn KC. 2011. Evaluation of compositional equivalence for multitrait biotechnology crops. J Agric Food Chem. 59:5865–5876. doi:10.1021/jf103874t.
  • Rigon CA, Gaines TA, Küpper A, Dayan FE. 2020. Metabolism-based herbicide resistance, the major threat among the non-target site resistance mechanisms. Outlooks Pest Manag. 31:162–168. doi:10.1564/v31_aug_04.
  • Rinaldo AR, Ayliffe M. 2015. Gene targeting and editing in crop plants: a new era of precision opportunities. Mol Breed. 35:1–15. doi:10.1007/s11032-015-0210-z.
  • Ritchie H, Roser M. 2021. Forests and deforestation. Published Online at OurWorldInData.org. [accessed 2022 June 25]. https://ourworldindata.org/forests-and-deforestation.
  • Robertson MJ, Holland JF, Cawley S, Potter TD, Burton W, Walton GH, Thomas G. 2002. Growth and yield differences between triazine-tolerant and non-triazine-tolerant cultivars of canola. Aust J Agric Res. 53:643–651. doi:10.1071/AR01159.
  • Rognli OA, Nilsson NO, Nurminiemi M. 2000. Effects of distance and pollen competition on gene flow in the wind-pollinated grass Festuca pratensis Huds. Heredity. 85:550–560.
  • Roldan MB, Cousins G, Muetzel S, Zeller WE, Fraser K, Salminen J-P, Blanca A, Kaur R, Richardson K, Maher D, et al. 2022. Condensed tannins in white clover (Trifolium repens) foliar tissues expressing the transcription factor TaMYB14-1 bind to forage protein and reduce ammonia and methane emissions in vitro. Front Plant Sci. 12:Article 777354. doi:10.3389/fpls.2021.777354.
  • Romeis J, Bartsch D, Bigler F, Candolfi MP, Gielkens M, Hartley SE, Hellmich RL, Huesing JE, Jepson PC, Layton R, Quemada H. 2008. Assessment of risk of insect-resistant transgenic crops to nontarget arthropods. Nature Biotechnol. 26:203–208.
  • Romeis J, Dutton A, Bigler F. 2004. Bacillus thuringiensis toxin (Cry1Ab) has no direct effect on larvae of the green lacewing Chrysoperla carnea (Stephens) (Neuroptera: Chrysopidae). J Insect Physiol. 50:175–183. doi:10.1016/j.jinsphys.2003.11.004.
  • Romeis J, Meissle M, Bigler F. 2006. Transgenic crops expressing Bacillus thuringiensis toxins and biological control. Nat Biotechnol. 24:63–71. doi:10.1038/nbt1180.
  • Romeis J, Meissle M, Naranjo SE, Li Y, Bigler F. 2014. The end of a myth – Bt (Cry1Ab) maize does not harm green lacewings. Front Plant Sci. 5:Article 391. doi:10.3389/fpls.2014.00391.
  • Römer S, Fraser P, Kiano J, Shipton CA, Misawa N, Schuch W, Bramley PM. 2000. Elevation of the provitamin A content of transgenic tomato plants. Nat Biotechnol. 18:666–669. doi:10.1038/76523.
  • Rommens CM, Yan H, Swords K, Richael C, Ye J. 2008. Low-acrylamide French fries and potato chips. Plant Biotechnol J. 6:843–853. doi:10.1111/j.1467-7652.2008.00363.x.
  • Rosic N, Bradbury J, Lee M, Baltrotsky K, Grace S. 2020. The impact of pesticides on local waterways: a scoping review and method for identifying pesticides in local usage. Environ Sci Pol. 106:12–21. doi:10.1016/j.envsci.2019.12.005.
  • Rosi-Marshall EJ, Tank JL, Royer TV, Whiles MR, Evans-White M, Chambers C, Griffiths NA, Pokelsek J, Stephen ML. 2007. Toxins in transgenic crop by-products may affect headwater stream ecosystems. Proc Natl Acad Sci. 104:16204–16208. https://www.pnas.org/doi/abs/10.1073pnas.0707177104.
  • Ruttan VW. 2004. Controversy about agricultural technology – lessons from the green revolution. Int J Biotechnol. 6:43–54.
  • Ryffel GU. 2014. Transgene flow: facts, speculations and possible countermeasures. GM Crops Food. 5:249–258. doi:10.4161/21645698.2014.945883.
  • Salyers A. 1996. The real threat from antibiotics. Nature. 384:304.
  • Sanchez-Leon S, Gil-Humanes J, Ozuna CV, Gimenez MJ, Carolina Sousa C, Voytas DF, Barro F. 2018. Low-gluten, non-transgenic wheat engineered with CRISPR/Cas9. Plant Biotechnol J. 16:902–910.
  • Sanchis V. 2011. From microbial sprays to insect-resistant transgenic plants: history of the biospesticide Bacillus thuringiensis. A review. Agron Sust. Dev. 31:217–231. doi:10.1051/agro/2010027.
  • Sanvido O, Romeis J, Bigler F. 2007. Ecological impacts of genetically modified crops: ten years of field research and commercial cultivation. In: Fiechter A, Sautter C, editors. Green gene technology. Advances in Biochemical Engineering/Biotechnology 107. Berlin: Springer; p. 235–278. doi:10.1007/10_2007_048.
  • Sasson A. 2018. Genetically modified crops (GM crops) and derived foods: brief review of their impact on health and environment, and of their social acceptance. Front Sci Eng. 8:1–52. [accessed 2022 June 26]. https://revues.imist.ma/index.php/fsejournal/article/download/27990/14625.
  • Sato S, Xing A, Ye X, Schweiger B, Kinney A, Graef G, Clemente T. 2004. Production of γ-linolenic acid and stearidonic acid in seeds of marker-free transgenic soybean. Crop Sci. 44:646–52. doi:10.2135/cropsci2004.0646.
  • Sayre R, Beeching JR, Cahoon EB, Egesi C, Fauquet C, Fellman J, Fregene M, Gruissem W, Mallowa S, Manary M, Maziya-Dixon B. 2011. The BioCassava plus program: biofortification of cassava for sub-Saharan Africa. Ann Rev Plant Biol. 62:251–272. doi:10.1146/annurev-arplant-042110-103751.
  • Schauzu M, Pöting A, Rubin D, Lampen A. 2012. Assessment of allergenicity of genetically modified food crops. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 55:402–407. doi:10.1007/s00103-011-1426-7. PMID: 22373855.
  • Scheitrum D, Schaefer KA, Nes K. 2020. Realized and potential global production effects from genetic engineering. Food Policy. 93:Article 101882. doi:10.1016/j.foodpol.2020.101882.
  • Schenkelaars P, Wesseler J. 2016. Farm-level GM coexistence policies in the EU: context, concepts and developments. EuroChoices. 15:5–11. doi:10.1111/1746-692X.12112.
  • Schlüter S, Großmann C, Diel J, Wu GM, Tischer S, Deubel A, Rücknagel J. 2018. Long-term effects of conventional and reduced tillage on soil structure, soil ecological and soil hydraulic properties. Geoderma. 332:10–19. doi:10.1016/j.geoderma.2018.07.001.
  • Schmidt CW. 2005. Genetically modified foods: breeding uncertainty. Environ Health Perspect. 113:A526–A533. doi:10.1289/ehp.113-a526.
  • Schmidt J, Braun C, Whitehouse L, Hilbeck A. 2009. Effects of activated Bt transgene products (Cry1Ab, Cry3Bb) on immature stages of the ladybird Adalia bipunctata in laboratory ecotoxicity testing. Arch Environ Contam Toxicol. 56:221–228. doi:10.1007/s00244-008-9191-9.
  • Schroeder E. 2022. Nigeria gives go-ahead to GMO wheat imports. Worldgrain.com. [accessed 2022 July 23]. https://www.world-grain.com/articles/17187-nigeria-gives-go-ahead-to-gmo-wheat-imports.
  • Schütte G, Eckerstorfer M, Rastelli V, Reichenbecher W, Restrepo-Vassalli S, Ruohonen-Lehto M, Saucy A-GW, Mertens M. 2017. Herbicide resistance and biodiversity: agronomic and environmental aspects of genetically modified herbicide-resistant plants. Environ Sci Eur. 29:Article 5. doi:10.1186/s12302-016-0100-y.
  • Schwach F, Baulcombe DC. 2016. RNA silencing in GM crops: introducing a technology and assessing the risks. A report for the Department for Environment, Food and Rural Affairs (DEFRA). p. 1–183. [accessed 2022 May 22]. https://www.plantsci.cam.ac.uk/system/files/documents/defra-report.pdf.
  • Scott D. 2003. Science and the consequences of mistrust: lessons from recent GM controversies. J Agric Environ Ethics. 16:569–82. doi:10.1023/B:JAGE.0000004963.59665.3d.
  • Sears MK, Hellmich RL, Stanley-Horn DE, Oberhauser KS, Pleasants JM, Mattila HR, Siegfried BD, Dively GP. 2001. Impact of Bt corn pollen on monarch butterfly populations: a risk assessment. Proc Natl Acad Sci. 981:937–11942.
  • Selb R, Wal JM, Moreno FJ, Lovik M, Mills C, Hoffmann-Sommergruber K, Fernandez A. 2017. Assessment of endogenous allergenicity of genetically modified plants exemplified by soybean – where do we stand? Food Chem Toxicol. 101:139–48. doi:10.1016/j.fct.2017.01.014.
  • Séralini GE, Cellier D, de Vendomois JS. 2007. New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. Arch Environ Contam Toxicol. 52:Article 596602. doi:10.1007/s00244-006-0149-5.
  • Séralini GE, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, Hennequin D, de Vendômois JS. 2012. Long-term toxicity of a roundup herbicide and a roundup tolerant genetically modified maize. Food Chem Toxicol. 50:4221–4231. doi:10.1016/j.fct.2012.08.005. For retraction notice refer – https://www.sciencedirect.com/science/article/pii/S0278691512005637/?imgSel=Y&_escaped_fragment_=.
  • Séralini GE, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, Hennequin D, de Vendômois JS. 2014. Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Environ Sci Eur. 26:Article 14. http://www.enveurope.com/content/26/1/14.
  • Shahbandeh M. 2022. Import volume of soybeans worldwide in 2021/22, by country. [accessed 2022 June 25]. https://www.statista.com/statistics/612422/soybeans-import-volumeworldwide-by-country/.
  • Shaheen SM, Antoniadis V, Shahid M, Yang Y, Abdelrahman H, Zhang T, Hassan NE, Bibi I, Niazi NK, Younis SA, Almazroui M. 2022. Sustainable applications of rice feedstock in agro-environmental and construction sectors: a global perspective. Renew Sustain Energy Rev. 153:Article 111791. doi:10.1016/j.rser.2021.111791.
  • Shaheen T, Irem S, Zafar Y. 2015. Biosafety risk of genetically modified crops containing cry genes. In: Lichtfouse E, Schwarzbauer J, Robert D, editors. CO2 sequestration, biofuels and depollution. 5. Cham: Springer; p. 307–334. doi:10.1007/978-3-319-11906-9_8.
  • Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu J-L, Gao C. 2013. Targeted genome modification of crop plants using a CRISPR-Cas system. Nat Biotechnol. 31:686–88. doi:10.1038/nbt.2650.
  • Shaner DL, Lindenmeyer RB, Ostlie MH. 2012. What have the mechanisms of resistance to glyphosate taught us? Pest Manag Sci. 68:3–9. doi:10.1002/ps.2261.
  • Shao X, Wu S, Dou T, Zhu H, Hu C, Huo H, He W, Deng G, Sheng O, Bi F, Gao H. 2020. Using CRISPR/Cas9 genome editing system to create MaGA20ox2 gene-modified semi-dwarf banana. Plant Biotechnol J. 18:17–19.
  • Sharma P, Singh SP, Iqbal HM, Parra-Saldivar R, Varjani S, Tong YW. 2022. Genetic modifications associated with sustainability aspects for sustainable developments. Bioengineered. 13:9509–9521.
  • Shehata AA, Schrödl W, Schledorn P, Krüger M. 2014. Distribution of glyphosate in chicken organs and its reduction by humic acid supplementation. Poultry Sci. 51:333–337. doi:10.2141/jpsa.0130169.
  • Shehryar K, Khan RS, Iqbal A, Hussain SA, Imdad S, Bibi A, Hamayun L, Nakamura I. 2020. Transgene Stacking as effective tool for enhanced disease resistance in plants. Mol Biotechnol. 62:1–7. doi:10.1007/s12033-019-00213-2.
  • Shelton AM, Zhao JZ, Roush RT. 2002. Economic, ecological, food safety, and social consequences of the deployment of Bt transgenic plants. Ann Rev Entomol. 47:845–881.
  • Shen CY, Jiao X-C, Li JB-Y, Jia P, Zhang X-W, Cheng X-H, Ren J-X, Lan H-D, Hou W-B, Fang M, et al. 2022. Evaluation of adverse effects/events of genetically modified food consumption: a systematic review of animal and human studies. Environ Sci Eur. 34:Article 8. doi:10.1186/s12302-021-00578-9.
  • Shen X. 2010. Understanding the evolution of rice technology in China – from traditional agriculture to GM rice today. J Dev Stud. 46:1026–1046. doi:10.1080/00220380903151033.
  • Sheoran S, Kumar S, Ramtekey V, Kar P, Meena RS, Jangir CK. 2022. Current status and potential of biofortification to enhance crop nutritional quality: an overview. Sustainability. 14:Article 3301. doi:10.3390/su14063301.
  • Shewmaker C, Sheehy JA, Daley M, Colburn S, Ke DY. 1999. Seed specific overexpression of phytoene synthase: increase in carotenoids and other metabolic effects. Plant J. 20:401–412. doi:10.1046/j.1365-313x.1999.00611.x.
  • Shewry PR. 2007. Improving the protein content and composition of cereal grain. J Cereal Sci. 46:239–250. doi:10.1016/j.jcs.2007.06.006.
  • Shi J, Gao H, Wang H, Lafitte HR, Archibald RL, Yang M, Hakimi SM, Mo H, Habben JE. 2017. ARGOS 8 variants generated by CRISPR-Cas9 improve maize grain yield under field drought stress conditions. Plant Biotechnol J. 15:207–216.
  • Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Menget X, et al. 2009. Precise genome modification in the crop species zea mays using zinc-finger nucleases. Nature. 459:437–441.
  • Sidhu RS, Hammond BG, Fuchs RL, Mutz J-N, Holden LR, George B, Olsen T. 2000. Glyphosate-tolerant corn:  the composition and feeding value of grain from glyphosate-tolerant corn is equivalent to that of conventional corn (Zea mays L.). J Agric Food Chem. 48:2305–2312. doi:10.1021/jf000172f.
  • Siegrist M. 2000. The influence of trust and perceptions of risks and benefits on the acceptance of gene technology. Risk Anal. 20:195–204. doi:10.1111/0272-4332.202020.
  • Sieradzki Z, Mazur M, Król B, Kwiatek K. 2021. Prevalence of genetically modified soybean in animal feeding stuffs in Poland. J Vet Res. 65:93–99. doi:10.2478/jvetres-2021-0012.
  • Sim JXF, Doolette CL, Vasileiadis S, Drigo B, Wyrsch ER, Djordjevic SP, Donner E, Karpouzas DG, Lombi E. 2022. Pesticide effects on nitrogen cycle related microbial functions and community composition. Sci Total Environ. 807:Article 150734. doi:10.1016/j.scitotenv.2021.150734.
  • Singh A, Taneja J, Dasgupta I, Mukherjee SK. 2015. Geminivirus resistance by artificial tasiRNA. Molecular Plant Pathol. 16:724–734. doi:10.1111/mpp.12229.
  • Singh HR, Hazarika P, Agarwala N, Bhatacharjee N, Bhagawati P, Gohain B, Bandyopadhyay T, Bharalee R, Gupta S, Deka M, Das S. 2018. Transgenic tea overexpressing Solanum tuberosum endo-1,3-beta-D-glucanase gene conferred resistance against blister blight disease. Plant Mol Biol Rep. 36:107–22. doi:10.1007/s11105-017-1063-x.
  • Singla-Pareek SL, Yadav SK, Pareek A, Reddy MK, Sopory SK. 2008. Enhancing salt tolerance in a crop plant by overexpression of glyoxalase II. Transgenic Res. 17:171–180. doi:10.1007/s11248-007-9082-2.
  • Skevas T, Fevereiro P, Wesseler J. 2010. Coexistence regulations and agriculture production: a case study of five Bt maize producers in Portugal. Ecol Econ. 69:2402–2408. doi:10.1016/j.ecolecon.2010.07.007.
  • Smale M, Zambrano P, Gruère G, Falck-Zepeda J, Matuschke I, Horna JD, Nagarajan L. 2009. Measuring the economic impacts of transgenic crops in developing agriculture during the first decade: approaches, findings, and future directions. Washington, DC: International Food Policy Research Institute. Food Policy Rev. 10. p. 1–107.
  • Smalla K, Borin S, Heuer H, Gebhard F, van Elsas JD, Nielsen K. 2000. Horizontal transfer of antibiotic resistance genes from transgenic plants to bacteria. In: Proceedings of the Sixth International Symposium on the Biosafety of Genetically Modified Organisms. p. 146–154.
  • Smith K, Spangenberg G. 2016. Considerations for managing agricultural co-existence between transgenic and non-transgenic cultivars of outcrossing perennial forage plants in dairy pastures. Agronomy. 6:Article 59. doi:10.3390/agronomy6040059.
  • Smyth S, Gusta M, Belcher K, Phillips P, Castle D. 2011. Changes in herbicide use after adoption of HR Canola in Western Canada. Weed Technol. 25:492–500. doi:10.1614/WT-D-10-00164.1.
  • Smyth SJ. 2017a. Genetically modified crops, regulatory delays, and international trade. Food Energy Secur. 6:78–86. doi:10.1002/fes3.100.
  • Smyth SJ. 2017b. Canadian regulatory perspectives on genome engineered crops. GM Crops Food. 8:35–43.
  • Smyth SJ, McHughen A, Entine J, Kershen D, Ramage C, Parrott W. 2021. Removing politics from innovations that improve food security. Transgenic Res. 30:601–612. doi:10.1007/s11248-021-00261-y.
  • Snell C, Bernheim A, Bergé J-B, Kuntz M, Pascal G, Paris A, Ricroch AE. 2012. Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: a literature review. Food Chem Toxicol. 50:1134–1148. doi:10.1016/j.fct.2011.11.048.
  • Sneller CH. 2003. Impact of transgenic genotypes and subdivision on diversity within elite North American soybean germplasm. Crop Sci. 43:409–414.
  • Snow A. 2002. Transgenic crops – why gene flow matters. Nat Biotechnol. 20:542. doi:10.1038/nbt0602-542.
  • Snow AA, Palma PM. 1997. Commercialization of transgenic plants: potential ecological risks. BioScience. 47:86–96.
  • Soares D, Silva L, Duarte S, Pena A, Pereira A. 2021. Glyphosate use, toxicity and occurrence in food. Foods. 10:Article 2785. doi:10.3390/foods10112785.
  • Sommer A, West KP Jr, editors. 1996. Vitamin A deficiency: health, survival and vision. New York: Oxford University Press; p. 1–438. ISBN 0-19-508824-7.
  • Sood N, Gupta S, Rath R, Saxena R. 2021. Genetically modified crops-need of the hour: an indian perspective. Vantage: J Themat Anal. 2:1–15. https://web.archive.org/web/20220420225134id_/http://journalvantage-maitreyi.com/images/Archive/05.%20GM%20crops.pdf.
  • Stein AJ, Sachdev HPS, Qaim M. 2006. Potential impact and cost effectiveness of Golden Rice. Nat Biotechnol. 24:1200–1201. https://www.nature.com/articles/nbt1006-1200b.pdf.
  • Steinbrecher RA. 2002. The CaMV 35S promoter. Government and corporate scientific incompetence: failure to assess the safety of GM crops. [accessed 2022 June 11]. https://www.econexus.info/publication/camv-35s-promoter.
  • Steinke K, Guertler P, Paul V, Wiedemann S, Ettle T, Albrecht C, Meye HHD, Spiekers H, Schwarz FJ. 2010. Effects of long-term feeding of genetically modified corn (event MON810) on the performance of lactating dairy cows. J Anim Physiol Anim Nutr. 94:e185–e193. doi:10.1111/j.1439-0396.2010.01003.x.
  • Stone GD, Glover D. 2017. Disembedding grain: Golden Rice, the green revolution, and heirloom seeds in the Philippines. Agric Hum Values. 34:87–102. doi:10.1007/s10460-016-9696-1.
  • Storer NP, Thompson GD, Head GP. 2012. Application of pyramided traits against Lepidoptera in insect resistance management for Bt crops. GM Crops Food. 3:154–162. doi:10.4161/gmcr.20945.
  • Stowe E, Dhingra A. 2021. Chapter 8. Development of the Arctic® Apple. In: Goldman I, editor. Plant breeding reviews Vol 44. p. 273–296. doi:10.1002/9781119717003.ch8.
  • Streletskii R, Astaykina A, Krasnov G, Gorbatov V. 2022. Changes in bacterial and fungal community of soil under treatment of pesticides. Agronomy. 12:Article 124. doi:10.3390/agronomy12010124.
  • Subramanian A, Qaim M. 2010. The impact of Bt cotton on poor households in rural India. J Dev Stud.ies. 46:295–311. http://www.tandfonline.com/doi/abs/10.108000220380903002954.
  • Sumangil FR. 2022 May 27. 7 provinces to produce ‘golden rice’. The Manila Times. [accessed 2022 June 2]. https://www.manilatimes.net/2022/05/27/news/regions/7-provinces-to-produce-golden-rice/1845154.
  • Sun Y, Jiao G, Liu Z, Zhang X, Li J, Guo X, Du W, Du J, Francis F, Zhao Y, Xia L. 2017. Generation of high-amylose rice through CRISPR/Cas9-mediated targeted mutagenesis of starch branching enzymes. Front Plant Sci. 8:Article 298. https://www.frontiersin.org/article/10.3389fpls.2017.00298.
  • Sun Y, Zhang X, Wu C, He Y, Ma Y, Hou H, Guo X, Du W, Zhao Y, Xia L. 2016. Engineering herbicide resistant rice plants through CRISPR/Cas9-mediated homologous recombination of acetolactate synthase. Mol Plant. 9:628–631. doi:10.1016/j.molp.2016.01.001.
  • Swiątkiewicz M, Bednarek D, Twardowska M, Markowski J, Mazur M, Sieradzki Z, Hanczakowska E, Kwiatek K. 2013. Genetically modified HT soybean meal and Bt maize in pig feeding. Wiadomości Zootechniczne. 51:31–47.
  • Tabashnik BE, Brevault T, Carriere Y. 2013. Insect resistance to Bt crops: lessons from the first billion acres. Nat Biotechnol. 31:510–521.
  • Tabashnik BE, Carriere Y. 2015. Successes and failures of transgenic Bt crops: global patterns of field-evolved resistance. In: Soberon M, Gao Y, Bravo A, editors. Bt resistance: characterization and strategies for GM crops producing Bacillus thuringiensis toxins. CABI Biotechnol Series 4. p. 1–14. ISBN 978-1-78064-437-0.
  • Tabashnik BE, Carriere Y. 2019. Global patterns of resistance to Bt crops highlighting pink bollworm in the United States, China, and India. J Econc Entomol. 112:2513–2523. doi:10.1093/jee/toz173.
  • Tabashnik BE, Mota-Sanchez D, Whalon ME, Hollingworth RM, Carriere Y. 2014. Defining terms for proactive management of resistance to Bt crops and pesticides. J Econ Entomol. 107:496–507.
  • Taheri EF, Azadi H, D’Haese M. 2017. A world without hunger: organic or GM crops? Sustainability. 9:Article 580. doi:10.3390/su9040580.
  • Tait J, Barker G. 2011. Global food security and the governance of modern biotechnologies: science & society series on food and science. EMBO Rep. 12:763–768.
  • Tallapragada M, Hardy BW, Lybrand E, Hallman WK. 2020. Impact of abstract versus concrete conceptualization of genetic modification (GM) technology on public perceptions. Risk Anal. 41:976–991. doi:10.1111/risa.13591.
  • Tan F, Wang J, Feng Y, Chi G, Kong H, Qiu H, Wei S. 2010. Bt corn plants and their straw have no apparent impact on soil microbial communities. Plant Soil. 329:349–364. doi:10.1007/s11104-009-0163-2.
  • Tang G, Qin J, Dolnikowski GG, Russell RM, Grusak MA. 2009. Golden Rice is an effective source of vitamin A. Am J Clin Nutr. 89:1776–1783. doi:10.3945/ajcn.2008.27119.
  • Tang M, He X, Luo Y, Ma L, Tang X, Huang K. 2013. Nutritional assessment of transgenic lysine-rich maize compared with conventional quality protein maize. J Sci Food Agric. 93:1049–54. doi:10.1002/jsfa.5845.
  • Tang W, Chen H, Xu C, Li X, Lin Y, Zhang Q. 2006. Development of insect-resistant transgenic indica rice with a synthetic cry1C* gene. Mol Breed. 18:1–10. doi:10.1007/s11032-006-9002-9.
  • Taylor M, Bickel A, Mannion R, Bell E, Harrigan GG. 2017. Dicamba-tolerant soybeans (Glycine max L.) MON 87708 and MON 87708 × MON 89788 are compositionally equivalent to conventional soybean. J Agric Food Chem. 65:8037–8045. doi:10.1021/acs.jafc.7b03844.
  • Teshima R, Akiyama H, Okunuki H, Sakushima JI. 2000. Effect of GM and non-GM soybeans on the immune system of BN rats and B10A mice. J. Food Hyg Soc Japan. 41:188–193.
  • The Royal Society. 2016. Is it safe to eat GM crops? [accessed 2022 Mat 28]. https://royalsociety.org/topics-policy/projects/gm-plants/is-it-safe-to-eat-gm-crops/.
  • Thomson J. 2013. Food for Africa: the life and work of a scientist in GM crops. Claremont: University of Cape Town Press. p. 181. ISBN 978 1 9204 9981 5.
  • Thomson JA. 2001. Horizontal transfer of DNA from GM crops to bacteria and to mammalian cells. J Food Sci. 66:188–93.
  • Thomson JG, Yau YY, Blanvillain R, Chiniquy D, Thilmony R, Ow DW. 2009. ParA resolvase catalyzes site-specific excision of DNA from the Arabidopsis genome. Transgenic Res. 18:237–248. doi:10.1007/s11248-008-9213-4.
  • Thuy NTP. 2018. Genetically-modified (GM) crops: sustaining or destructing agriculture-the case of Monsanto. Eur J Econd Manag Sci. 1:67–76.
  • Tilman D, Downing JA. 1994. Biodiversity and stability in grasslands. Nature. 367:363–365.
  • Tilman D, Isbell F, Cowles JM. 2014. Biodiversity and ecosystem functioning. Ann Rev Environ Res. 45:471–493.
  • Tirado R, Johnston P. 2010. Food security: GM crops threaten biodiversity. Science. 328:170–171.
  • Tonukari NJ, Omotor DG. 2010. Biotechnology and food security in developing countries. Biotechnol Mol Biol Rev. 4:13–23.
  • Trabalza-Marinucci M, Brandi G, Rondini C, Avellini L, Giammarini C, Costarelli S, Acuti G, Orlandi C, Filippini G, Chiaradia E, Malatesta M. 2008. A three year longitudinal study on the effects of a diet containing genetically modified Bt176 maize on the health status and performance of sheep. Livestock Sci. 113:178–190. doi:10.1016/j.livsci.2007.03.009.
  • Tricoll DM, Carney KJ, Russell PF, McMaster JR, Groff DW, Hadden KC, Himmel PT, Hubbard JP, Boeshore ML, Quemada HD. 1995. Field evaluation of transgenic squash containing single or multiple virus coat protein gene constructs for resistance to cucumber mosaic virus, watermelon mosaic virus 2, and zucchini yellow mosaic virus. Nat Biotechnol. 13:1458–1465.
  • Trigo EJ, Cap EJ. 2003. The impact of the introduction of transgenic crops in Argentinean agriculture. AgBioForum. 6:87–94.
  • Tripathi JN, Ntui VO, Ron M, Muiruri SK, Britt A, Tripathi L. 2019. CRISPR/Cas9 editing of endogenous banana streak virus in the B genome of Musa spp. overcomes a major challenge in banana breeding. Commun Biol. 2:1–11.
  • Tudisco R, Lombardi P, Bovera F, Cutrignelli MI, Mastellone V, Terzi V, Avallone L, Infascelli F. 2006. Genetically modified soyabean in rabbit feeding: detection of DNA fragments and evaluation of metabolic effects by ezymatic analysis. J Anim Sci. 82:193–99. doi:10.1079/ASC200530.
  • Turnbull C, Lillemo M, Hvoslef-Eide TAK. 2021. Global regulation of genetically modified crops amid the gene edited crop boom – a review. Front Plant Sci. 12:Article 630396. doi:10.3389/fpls.2021.630396.
  • Turrini A, Sbrana C, Giovannetti M. 2015. Belowground environmental effects of transgenic crops: a soil microbial perspective. Res Microbiol. 166:121–131. doi:10.1016/j.resmic.2015.02.006.
  • Tuteja N, Verma S, Sahoo RK, Raveendar S, Reddy IN. 2012. Recent advances in development of marker-free transgenic plants: regulation and biosafety concern. J Biosci. 37:167–197. doi:10.1007/s12038-012-9187-5.
  • Tyczewska A, Woźniak E, Gracz J, Kuczynski J, Twardowski T. 2018. Towards food security: current state and future prospects of agrobiotechnology. Trends Biotechnol. 36:1219–1229.
  • Tyukavina A, Hansen MC, Potapov PV, Stehman SV, Smith-Rodriguez K, Okpa C, Aguilar R. 2017. Types and rates of forest disturbance in Brazilian Legal Amazon, 2000–2013. Sci Adv. 3:Article e1601047. doi:10.1126/sciadv.1601047.
  • Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O, Napier JA. 2015. Field trial evaluation of the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Camelina sativa: making fish oil substitutes in plants. Metab Eng Commun. 9:93–98.
  • van den Belt H. 2003. Debating the precautionary principle: ‘guilty until proven innocent’ or ‘Innocent until proven guilty’? Plant Physiol. 132:1122–1126. doi:10.1104/pp.103.023531.
  • Van den Berg J, Hilbeck A, Bøhn T. 2013. Pest resistance to Cry1Ab Bt maize: field resistance, contributing factors and lessons from South Africa. Crop Protect. 54:154–160. doi:10.1016/j.cropro.2013.08.010.
  • Vandenberg LN, Blumberg B, Antoniou MN, Benbrook CM, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R. 2017. Is it time to reassess current safety standards for glyphosate-based herbicides? J Epidemiol Community Health. 71:613–618. doi:10.1136/jech-2016-208463.
  • van der Voet H, Paoletti C. 2019. Equivalence testing approaches in genetically modified organism risk assessment. J Agric Food Chem. 67:13506–13508. doi:10.1021/acs.jafc.9b05149.
  • van de Wiel CCM, Groot MHM, den Nijs HCM. 2003. Gene flow from crops to wild plants and its population-ecological consequences in the context of GM-crop biosafety, including some recent experiences from lettuce. In: Proceedings of the Frontis Workshop on Environmental Costs and Benefits of Transgenic Crops Wageningen, The Netherlands 1–4 June 2003. No. 7. Springer; p. 97–110.
  • Van Eenennaam AL. 2013. GMOs in animal agriculture: time to consider both costs and benefits in regulatory evaluations. J Anim Sci Biotechnol. 4:Article 37. doi:10.1186/2049-1891-4-37.
  • Van Eenennaam AL, Young AE. 2014. Prevalence and impacts of genetically engineered feedstuffs on livestock populations. J Anim Sci. 92:4255–4278. doi:10.2527/jas.2014-8124.
  • van Elsas JD, Trevors JT, Starodub ME. 1988. Bacterial conjugation between pseudomonads in the rhizosphere of wheat. FEMS Microbiol Ecol. 4:299–306. doi:10.1111/j.1574-6968.1988.tb02676.x-i1.
  • van Elsas JD, Turner S, Bailey MJ. 2003. Horizontal gene transfer in the phytosphere. New Phytol. 157:525–537.
  • Vasavirama K, Kirti PB. 2012. Increased resistance to late leaf spot disease in transgenic peanut using a combination of PR genes. Funct Int Genom. 12:625–634. doi:10.1007/s10142-012-0298-8.
  • Vecchio L, Cisterna B, Malatesta M, Martin TE, Biggiogera M. 2004. Ultrastructural analysis of testes from mice fed on genetically modified soybean. Eur J Histochem. 48:448–454.
  • Vega Rodríguez A, Rodríguez-Oramas C, Sanjuán Velázquez E, Hardisson de la Torre A, Rubio Armendáriz C, Carrascosa Iruzubieta C. 2022. Myths and realities about genetically modified food: a risk-benefit analysis. Appl. Sci. 12:Article 2861. doi:10.3390/app12062861.
  • Velimirov A, Binter C, Zentek J. 2008. Biological effects of transgenic maize NK603xMON810 fed in long term reproduction studies in mice. Familie und Jugend Report, Forschungsberichte der Sektion IV Band 3.
  • Vencill W, Nichols R, Webster T, Soteres J, Mallory-Smith C, Burgos N, Johnson WG, McClelland M. 2012. Herbicide resistance: toward an understanding of resistance development and the impact of herbicide-resistant crops. Weed Sci. 60:2–30. doi:10.1614/WS-D-11-00206.1.
  • Venkatesh TV, Breeze ML, Liu K, Harrigan GG, Culler AH. 2014. Compositional analysis of grain and forage from MON 87427, an inducible male sterile and tissue selective glyphosate-tolerant maize product for hybrid seed production. J Agric Food Chem. 62:1964–1973. doi:10.1021/jf4041589.
  • Venus TJ, Dillen K, Punt MJ, Wesseler JHH. 2017. The costs of coexistence measures for genetically modified maize in Germany. J Agric Econ. 68:407–426. doi:10.1111/1477-9552.12178.
  • Verhoeckx K, Bøgh KL, Dupont D, Egger L, Gadermaier G, Larré C, Mackie A, Menard O, Adel-Patient K, Picariello G, Portmann R. 2019. The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST. Food Chem Toxicol. 129:405–423. doi:10.1016/j.fct.2019.04.052.
  • Verma SR. 2013. Genetically modified plants: public and scientific perceptions. ISRN Biotechnol. 2013:Article 820671. doi:10.5402/2013/820671.
  • Verma V, Negi S, Kumar P, Srivastava DK. 2021. Global status of genetically modified crops. In: Kumar Srivastava D, Kumar Thakur A, Kumar P, editor. Agricultural biotechnology: latest research and trends. Singapore: Springer; p. 305–322. doi:10.1007/978-981-16-2339-4_13.
  • Vicini JL. 2017. GMO crops in animal nutrition. Anim Front. 7:9–14. doi:10.2527/af.2017.0113.
  • Vicini JL, Reeves WR, Swarthout JT, Karberg KA. 2019. Glyphosate in livestock: feed residues and animal health. J Anim Sci. 97:4509–4518. doi:10.1093/jas/skz295.
  • Viswanathan PK, Lalitha N. 2010. GM technology and sustainable agriculture future: empirical evidences from Bt cotton farmers in Maharashtra and Gujarat in India. J Dev Agric Econ. 2:7–17.
  • Vitale J, Vognan G, Ouattarra M. 2014. Chapter 38. Cotton. In: Smyth SJ, Phillips PWB, Castle D, editors. Handbook on agriculture, biotechnology and development. Cheltenham: Edward Elgar Publishing Ltd; p. 604–620.
  • Vogt-Schilb A, Hallegatte S. 2017. Climate policies and nationally determined contributions: reconciling the needed ambition with the political economy. WIREs Energy Environ. 6:Article e256. doi:10.1002/wene.256.
  • von Braun J. 2010. Food insecurity, hunger and malnutrition: necessary policy and technology changes. New Biotechnol. 27:449–452. doi:10.1016/j.nbt.2010.08.006.
  • Vulchi R, Bagavathiannan M, Nolte SA. 2022. History of herbicide-resistant traits in cotton in the U.S. and the importance of integrated weed management for technology stewardship. Plants. 11:Article 1189. doi:10.3390/plants11091189.
  • Wakelin A, Preston C. 2006. A target-site mutation is present in a glyphosate-resistant Lolium rigidum population. Weed Res. 46:432–440. doi:10.1111/j.1365-3180.2006.00527.x.
  • Waltz E. 2015a. Monsanto adds dicamba to its cache to counter weed threat. Nat. Biotechnol. 33:Article 328. doi:10.1038/nbt0415-328.
  • Waltz E. 2015b. Non-browning GM apple cleared for market. Nature Biotechnology. 33:326–328.
  • Wamatsembe IM, Asea G, Haefele SM. 2017. A survey: potential impact of genetically modified maize tolerant to drought or resistant to stem borers in Uganda. Agronomy. 7:Article 24. doi:10.3390/agronomy7010024.
  • Wang M, Guan X. 2020. The effects of phytase transgenic maize on the community components and diversity of arthropods. J Asia-Pacific Entomol. 23:1228–1234. doi:10.1016/j.aspen.2020.09.001.
  • Wang S, Just DR, Pinstrup-Andersen P. 2008. Bt cotton and secondary pests. Int J Biotechnol. 10:113–121.
  • Wang X, He X, Zou S, Xu W, Jia X, Zhao B, Zhao C, Huang K, Liang Z. 2016. A subchronic feeding study of dicamba-tolerant soybean with the dmo gene in Sprague–Dawley rats. Reg Toxicol Pharmacol. 77:134–142. doi:10.1016/j.yrtph.2016.02.001.
  • Wang Y, Cheng X, Shan Q, Zhang Y, Liu J, Gao C, Qiu J-L. 2014. Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nat Biotechnol. 32:947–951. doi:10.1038/nbt.2969.
  • Wang Z, Lawrence R, Hopkins A, Bell J, Scott M. 2004. Pollen-mediated transgene flow in the wind-pollinated grass species tall fescue (Festuca arundinacea Schreb.). Molecular Breeding. 14:47–60. doi:10.1023/B:MOLB.0000037994.26287.17.
  • Wang Z-Y, Brummer EC. 2012. Is genetic engineering ever going to take off in forage, turf and bioenergy crop breeding? Ann Bot. 110:1317–1325. doi:10.1093/aob/mcs027.
  • Warwick SI, Légère A, Simard M-J, James T. 2008. Do escaped transgenes persist in nature? The case of an herbicide resistance transgene in a weedy Brassica rapa population. Mol Ecol. 17:1387–1395. doi:10.1111/j.1365-294X.2007.03567.x.
  • Warwick SI, Simard MJ, Légère A, Beckie HJ, Braun L, Zhu B, Mason P, Seguin-Swartz G, Stewart CN. 2003. Hybridization between transgenic Brassica napus L. and its wild relatives: Brassica rapa L., Raphanus raphanistrum L., Sinapis arvensis L., and Erucastrum gallicum (Willd.) O.E. Schulz. Theor Appl Genet. 107:528–539. doi:10.1007/s00122-003-1278-0.
  • Watkinson AR, Freckleton RP, Robinson RA, Sutherland WJ. 2000. Predictions of biodiversity response to genetically modified herbicide-tolerant crops. Science. 289:1554–1557.
  • Watrud LS, Lee EH, Fairbrother A, Burdick C, Reichman JR, Bollman M, Storm M, King G, Van de Water PK. 2004. Evidence for landscape-level, pollen-mediated gene flow from genetically modified creeping bentgrass with CP4 EPSPS as a marker. Proc Nat Acad Sci. 101:14533–14538. doi:10.1073/pnas.0405154101.
  • Weedscience. 2022. Weeds resistant to inhibition of enolpyruvyl shikimate phosphate synthase HRAC group 9 (Legacy G). [accessed 2022 June 18]. https://www.weedscience.org/Pages/MOA.aspx?MOAID=12.
  • Wei M, Tan F, Zhu H, Cheng K, Wu X, Wang J, Zhao K, Tang X. 2012. Impact of Bt-transgenic rice (SHK601) on soil ecosystems in the rhizosphere during crop development. Plant Soil Environ. 58:217–223.
  • Welk AK, Kleine-kalmer R, Daum D, Enneking U. 2021. Acceptance and market potential of iodine-biofortified fruit and vegetables in Germany. Nutrients. 13:Article 4198. doi:10.3390/nu13124198.
  • Wen S, Liu H, Li X, Chen X, Hong Y, Li H, Lu Q, Liang X. 2018. TALEN-mediated targeted mutagenesis of fatty acid desaturase 2 (FAD2) in peanut (Arachis hypogaea L.) promotes the accumulation of oleic acid. Plant Mol Biol. 97:177–185.
  • Wesseler J. 2022. The EU's farm-to-fork strategy: an assessment from the perspective of agricultural economics. Appl Econ Perspect Policy. 1–18. doi:10.1002/aepp.13239.
  • Wesseler J, Bonanno A, Drabik D, Materia VC, Malaguti L, Meyer M, Venus TJ. 2015. Overview of the agricultural input sector in the EU. Directorate – General for internal policies. Policy Department B: Structural and Cohesion Policies. Agriculture and Rural Development. p. 128. ISBN 978-92-823-7922-6. doi:10.2861/49815.
  • Wesseler J, Scatasta S, Fall EH. 2011. Chapter 7. The environmental benefits and costs of genetically modified (GM) crops. In: Carter CA, Moschini G, Sheldon I, editors. Genetically modified food and global welfare. 10. Bingley: Emerald Group Publishing Limited; p. 173–199. doi:10.1108/S1574-8715(2011)0000010012.
  • Wesseler J, Scatasta S, Nillesen E. 2007. The maximum incremental social tolerable irreversible costs (MISTICs) and other benefits and costs of introducing transgenic maize in the EU-15. Pedobiologia. 51:261–269. doi:10.1016/j.pedobi.2007.04.004.
  • Wesseler J, Zilberman D. 2014. The economic power of the Golden Rice opposition. Environ Dev Econ. 19:724–742. doi:10.1017/S1355770X1300065X.
  • Whitehouse MEA, Wilson LJ, Fitt GP. 2005. A comparison of arthropod communities in transgenic Bt and conventional cotton in Australia. Environ Entomol. 34:1224–1241. doi:10.1093/ee/34.5.1224.
  • Whitty CJM, Jones M, Tollervey A, Wheeler T. 2013. Africa and Asia need a rationale debate on GM crops. Nature. 497:31–33.
  • Wilkinson MJ, Elliott LJ, Allainguillaume J, Shaw MW, Norris C, Welters R, Alexander M, Sweet J, Mason DC. 2003. Hybridization between Brassica napus and B. rapa on a national scale in the United Kingdom. Science. 302:457–459. doi:10.1126/science.1088200.
  • Wilkinson MJ, Ford CS. 2007. Estimating the potential for ecological harm from gene flow to crop wild relatives. Collect Biosaf Rev. 3:42–47.
  • Williams JA, West CJ. 2000. Environmental weeds in Australia and New Zealand: issues and approaches to management. Austral Ecol. 25:425–444. doi:10.1046/j.1442-9993.2000.01081.x.
  • Winichayakul S, Beechey-Gradwell Z, Muetzel S, Molano G, Crowther T, Lewis S, Xue H, Burke J, Bryan G, Roberts NJ. 2020. In vitro gas production and rumen fermentation profile of fresh and ensiled genetically modified high–metabolizable energy ryegrass. J Dairy Sci. 103:2405–2418. doi:10.3168/jds.2019-16781.
  • Wintermantel WM, Schoelz JE. 1996. Isolation of recombinant viruses between cauliflower mosaic virus and a viral gene in transgenic plants under conditions of moderate selection pressure. Virology. 223:156–164. doi:10.1006/viro.1996.0464.
  • Wolfenbarger LL, Phifer PR. 2000. The ecological risks and benefits of genetically engineered plants. Science. 290:2088–2093. https://www.science.org/doi/abs/10.1126science.290.5499.2088.
  • Wolt JD, Peterson RKD, Bystrak P, Meade T. 2003. A screening level approach for nontarget insect risk assessment: transgenic Bt corn pollen and the monarch butterfly (Lepidoptera: danaidae). Environ Entomol. 32:237–246.
  • Woodfield DR, Clifford PTP, Baird IJ, Cousins GR. 1995. Gene flow and estimated isolation requirements for transgenic white clover. In: Jones DD, editor. Proceedings of the 3rd International Symposium on the Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms. Oakland: University of California; p. 509–514.
  • World Perspectives Inc. 2022. Consumer price impacts of Mexican restrictions on GM corn: an economic analysis. Arlington (VA): World Perspectives Inc; p. 51.
  • Wortmann L, Enneking U, Daum D. 2018. German consumers’ attitude towards selenium-biofortified apples and acceptance of related nutrition and health claims. Nutrients. 10:Article 190. doi:10.3390/nu10020190.
  • Wossink A, Denaux ZS. 2006. Environmental and cost efficiency of pesticide use in transgenic and conventional cotton production. Agric Syst. 90:312–328. doi:10.1016/j.agsy.2006.01.004.
  • Wu F. 2006. Mycotoxin reduction in Bt corn: potential economic, health, and regulatory impacts. Transgenic Res. 15:277–289. doi:10.1007/s11248-005-5237-1.
  • Wu F, Wesseler J, Zilberman D, Russell RM, Chen C, Dubock AC. 2021. Allow Golden Rice to save lives. Proc Nat Acad Sci. 118:e2120901118. doi:10.1073/pnas.212090111.
  • Wu KM, Lu YH, Feng HQ, Jiang YY, Zhao J Z. 2008. Suppression of cotton bollworm in multiple crops in China in areas with Bt toxin-containing cotton. Science. 321:1676–1678.
  • Wu W, Lu H, Liu W, Devare M, Theis JE, Chen Y. 2009. Decomposition of Bacillus thuringiensis (Bt) transgenic rice residues (straw and roots) in paddy fields. J Soils Sediments. 9:457–467. doi:10.1007/s11368-009-0106-9.
  • Xu D, Geng L, Li N, Liu X, Lu F, Zhang J. 2015b. The residue detection of cry1Ab/Ac gene and protein in the gut of Rattus norvegicus feeding transgenic rice. Biotechnol Bull. 31:131–137.
  • Xu D, Geng L, Zhang M, Lu F, Zhang J. 2015a. Detection of cry1Ab/Ac gene and protein remained in gut of broiler feeding transgenic rice. Biotechnol Bull. 31:84–90.
  • Xu Z, Hennessy DA, Sardana K, Moschini G. 2013. The realized yield effect of genetically engineered crops: US maize and soybean. Crop Sci. 53:735–745. doi:10.2135/cropsci2012.06.0399.
  • Xu Z, Xu X, Gong QZ, Li Z, Li Y, Wang S, Yang Y, Ma W, Liu L, Zhu B, et al. 2019. Engineering broad-spectrum bacterial blight resistance by simultaneously disrupting variable TALE-binding elements of multiple susceptibility genes in rice. Mol Plant. 12:1434–1446.
  • Yang F, Kerns DL, Head GP, Leonard BR, Levy R, Niu Y, Huang F. 2014. A challenge for the seed mixture refuge strategy in Bt maize: impact of cross-pollination on an ear-feeding pest, corn earworm. PLoS One. 9:Article e112962. doi:10.1371/journal.pone.0112962.
  • Yang SH, Moran DL, Jia HW, Bicar EH, Lee M, Scott MP. 2002. Expression of a synthetic porcine alpha-lactalbumin gene in the kernels of transgenic maize. Transgenic Res. 11:11–20. doi:10.1023/A:1013996129125.
  • Yavari B, Sarami S, Shahgaldi S, Athari SS, Sharma A. 2016. If there is really a notable concern about allergenicity of genetically modified foods? J Food Quality Hazards Control. 10:3–9.
  • Ye X, Al-Bbili S, Kloti A, Zhang J, Lucca P, Beyer P, Potrykus I. 2000. Engineering the Provitamin A (β-Carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science. 287:303–305. https://www.science.org/doi/abs/10.1126science.287.5451.303.
  • Yin JQ, Wang DM, Liang JG, Song XY. 2022. Negligible impact of drought-resistant genetically modified maize on arthropod community structure observed in a 2-year field investigation. Plants. 11:Article 1092. doi:10.3390/plants11081092.
  • Yorobe JM, Smale M. 2012. Impacts of Bt maize on smallholder income in the Philippines. AgBioForum. 15:152–162. http://hdl.handle.net/10355/16006.
  • Yoshida S, Maruyama S, Nozaki H, Shirasu K. 2010. Horizontal gene transfer by the parasitic plant Striga hermonthica. Science. 328:Article 1128.
  • Young J, Cormick G. 2004. Public concerns towards GM foods are not driven solely by concerns about the technology, but more strongly by cultural differences. PCST International Conference p. 1–4. [accessed 2022 July 24]. https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.738.1475&rep=rep1&type=pdf.
  • Yu C, Deng H, Hu R. 2020. Attitude gaps with respect to GM non-food crops and GM food crops and confidence in the government’s management of biotechnology: evidence from Beijing consumers, Chinese farmers, journalists, and government officials. Sustainability. 12:Article 24. doi:10.3390/su12010324.
  • Yu H, Li Y, Li X, Romeis J, Wu K. 2013. Expression of Cry1Ac in transgenic Bt soybean lines and their efficiency in controlling lepidopteran pests. Pest Manag Sci. 69:1326–1333. doi:10.1002/ps.3508.
  • Yum HY, Lee SY, Lee KE, Sohn MH, Kim KE. 2005. Genetically modified and wild soybeans: an immunologic comparison. Allergy Asthma Proc. 26:210216.
  • Zerbe N. 2004. Feeding the famine? American food aid and the GMO debate in Southern Africa. Food Pol. 29:593–608. doi:10.1016/j.foodpol.2004.09.002.
  • Zhang A, Liu Y, Wang F, Li T, Chen Z, Kong D, Bi J, Zhang F, Luo X, Wang J, et al. 2019. Enhanced rice salinity tolerance via CRISPR/Cas9-targeted mutagenesis of the OsRR22 gene. Mol Breed. 39:1–10.
  • Zhang C, Shi G, Shen J, Hu R. 2015. Productivity effect and overuse of pesticide in crop production in China. J Integr Agric. 14:1903–1910.
  • Zhang C, Wohlhueter R, Zhang H. 2016. Genetically modified foods: a critical review of their promise and problems. Food Sci Human Wellness. 5:116–123. doi:10.1016/j.fshw.2016.04.002.
  • Zhang G, Wan F, Guo J, Hou M. 2004. Expression of Bt toxin in transgenic Bt cotton and its transmission through pests (Helicoverpa armigera) and (Aphis gossypii) to natural enemy (Propylaea japonica) in cotton plots Kun Chong xue bao. Acta Entomol Sinica. 47:334–341.
  • Zhang GF, Wan FH, Lovei GL, Liu WX, Guo JY. 2006. Transmission of Bt toxin to the predator Propylaea japonica (Coleoptera: Coccinellidae) through its aphid prey feeding on transgenic Bt cotton. Environ Entomol. 35:143–150. doi:10.1603/0046-225X-35.1.143.
  • Zhang HX, Blumwald E. 2011. Transgenic salt-tolerant tomato plants accumulate salt in foliage but not in fruit. Nat Biotechnol. 19:765–8.
  • Zhang L, Yang X-D, Zhang Y-Y, Yang J, Qi G-X, Guo D-Q, Xing G-J, Yao Y, Xu W-J, Li H-Y, et al. 2014. Changes in oleic acid content of transgenic soybeans by antisense RNA mediated posttranscriptional gene silencing. Int J Genom. 8:Article 921950. doi:10.1155/2014/921950.
  • Zhang Y, Bai Y, Wu G, Zou S, Chen Y, Gao C, Tang D. 2017. Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat. Plant J. 91:714–724. doi:10.1111/tpj.13599.
  • Zhang Z, Guo Y, Marasigan KM, Conner JA, Ozias-Akins P. 2022. Gene activation via Cre/lox-mediated excision in cowpea (Vigna unguiculata). Plant Cell Rep. 41:119–138. doi:10.1007/s00299-021-02789-z.
  • Zhao JH, Ho P, Azadi H. 2011. Benefits of Bt cotton counterbalanced by secondary pests? Perceptions of ecological change in China. Environ Monit Assess. 173:173–994. doi:10.1007/s10661-010-1439-y.
  • Zhao JZ, Li YX, Collins HL, Cao J, Earle ED, Shelton AM. 2001. Different cross resistance patterns in the diamondback moth (Lepidoptera: Plutellidae) resistant to Bacillus thuringiensis toxin Cry1C. J Econ Entomol. 94:1547–1552. doi:10.1603/0022-0493-94.6.1547.
  • Zhong F, Li Y, Xin J, Wang Z, Wang L, Chai J. 2014. A 22 week subchronic feeding study of transgenic BADH alfalfa in rabbits. Res Opin Anim Vet Sci. 4:172–177.
  • Zhou H, Berg JD, Blank SE, Chay CA, Chen G, Eskelsen SR, Fry JE, Hoi S, Hu T, Isakson PJ, et al. 2003. Field efficacy assessment of transgenic roundup ready wheat roundup and roundup ready are trademarks of Monsanto company. Crop Sci. 43:1072–1075. doi:10.2135/cropsci2003.1072.
  • Zhou J, Ma C, Xu H, Yuana K, Lua X, Zhub Z, Wuc Y, Xu G. 2009. Metabolic profiling of transgenic rice with cryIAc and sck genes: an evaluation of unintended effects at metabolic level by using GCFID and GCMS. J Chromatogr B Analyt Technol Biomed Life Sci. 877:725–732. doi:10.1016/j.jchromb.2009.01.040.
  • Zhou Q, Mao P, Luo D, Chai X, Deng H, Fang Q, Fang L, Nan Z, Wen J, Liu Z. 2022. Comparative transcriptome analyses reveal that the MsNST1 gene affects lignin synthesis in alfalfa (Medicago sativa L.). Crop J. doi:10.1016/j.cj.2022.02.002.
  • Zhu C, Naqvi S, Gomez-Galera S, Pelacho AM, Capell T, Christou P. 2007. Transgenic strategies for the nutritional enhancement of plants. Trends Plant Sci. 12:548–555. doi:10.1016/j.tplants.2007.09.007.
  • Zhu S, Duwal A, Su Q, Vossen JH, Visser RGF, Jacobsen E. 2013. Vector integration in triple R gene transformants and the clustered inheritance of resistance against potato late blight. Transgenic Res. 22:315–325. doi:10.1007/s11248-012-9644-9.
  • Zhu Y, Li D, Wang F, Yin J, Jin H. 2004. Nutritional assessment and fate of DNA of soybean meal from Roundup Ready or conventional soybeans using rats. Arch Anim Nutr. 58:295–310.
  • Zilberman D, Kaplan S, Kim E, Hochman G, Graff G. 2013. Continents divided. GM Crops Food. 4:202–208. doi:10.4161/gmcr.26981.
  • Zilberman D, Kaplan S, Wesseler J. 2015. The loss from underutilizing GM technologies. AgBioForum. 18:312–319. https://hdl.handle.net/10355/48146.
  • Zimny T, Eriksson D. 2020. Exclusion or exemption from risk regulation? EMBO Reports. 21:e51061. doi:10.15252/embr.202051061.
  • Zobiole LHS, Oliveira RS Jr, Kremer RJ, Muniz AS, Oliviera A Jr. 2010. Nutrient accumulation and photosynthesis in glyphosate-resistant soybeans is reduced under glyphosate use. J Plant Nutr. 33:1860–1873.
  • Zwahlen C, Andow DA. 2005. Field evidence for the exposure of ground beetles to Cry1Ab from transgenic corn. Environ Biosafe Res. 4:113–117. doi:10.1051/ebr:2005014.
  • Zydenbos S. 2008. Arable farming. Te Ara – the encyclopedia of New Zealand. [accessed 2022 July 10]. http://www.TeAra.govt.nz/en/arable-farming.

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