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Scandinavian Journal of Clinical and Laboratory Investigation Volume 37, 1977 - Issue 5
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Original Article

Principles of albumin and IgG analyses in neurological disorders. III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis

H. Link Department of Neurology and Department of Clinical Chemistry, University Hospital, LinkÖping, Sweden
&
G. Tibbling Department of Neurology and Department of Clinical Chemistry, University Hospital, LinkÖping, Sweden
Pages 397-401 | Received 10 Feb 1976, Accepted 05 Apr 1977, Published online: 28 Aug 2009

References

  • Cohen S., Bannister R. Immunoglobulin synthesis within the central nervous system in multiple sclerosis. Lancet 1967; 1: 366
  • Frick E., Scheid-Seydel L. Untersuchungen. mit J131-markiertem γ-Globulin zur Frage der Abstammung der Liquoreiveisskörper. Klin. Wschr. 1958; 36: 857
  • Ganrot K., Laurell C.-B. Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation. Clin. Chem. 1974; 571
  • Kabat E. A., Freedman D. A., Murray J. P., Knaub V. A study of the crystalline albumin, gamma globulin and total protein in the cerebrospinal fluid of one hundred cases of multiple sclerosis and in other diseases. Amer. J. med. Sci. 1950; 219: 55
  • Laterre E. C., Callawaert A., Heremans J. F. Electrophoretic morphology of gamma globulins in cerebrospinal fluid of multiple sclerosis and other diseases of the nervous system. Neurology 1970; 20: 982
  • Link H. Immunoglobulin G and low molecular molecular weight protein in human cerebrospinal fluid. Chemical and immunological characterisation with special reference to multiple sclerosis. Acta neurol. scand. 1967; 43(Suppl. 28)
  • Link H., Müller R. Immunoglobulins in multiple sclerosis and infections of the nervous system. Arch. Neurol. 1971; 25: 326
  • Link H., Tibbling G. Principles of albumin and IgG analyses in neurological disorders. II. Influence of serum concentration on CSF and evaluation of blood-brain barrier damage. Scand. J. clin. Lab. Invest. 1977; 37: 391
  • Müller R. Studies on multiple sclerosis. Acta med. scand. 1949; 133(Suppl. 222)
  • Sandberg-Wollheim M. Immunoglobulin synthesis in vitro by cerebrospinal fluid cells in patients with multiple sclerosis. Scand. J. Immunol. 1974; 3: 717
  • Tibbling G., Link H., Öhman S. Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values. Scand. J. din. Lab. Invest. 1977; 37: 385
  • Tourtellotte W. W. Multiple sclerosis cerebrospinal fluid. Handbook of Clinical Neurology, P. J. Vinken, G. W. Bruyn. North-Holland Publ. Comp., Amsterdam 1970
  • Yahr M. D., Goldensohn S. S., Kabat E. A. Further studies on the gamma globulin content of cerebrospinal fluid in multiple sclerosis and other neurological disorders. Ann. N. Y. Acad. Sci. 1954; 58: 613

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