Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 37, 2002 - Issue 6
Submit an article Journal homepage
65
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Gut Inflammation Modulated by the Enteric Nervous System and Neurotrophic Factors

G. B. T. von Boyen
,
M. Reinshagen
,
M. Steinkamp
,
G. Adler
&
J. Kirsch
Pages 621-625 | Published online: 08 Jul 2009

  • Purness JB, Costa M. The enteric nervous system. New York: Churchill Livingstone; 1987.
  • Gershon MD, Kirchgessner AL, Wade PR. Functional anatomy of the enteric nervous system. In: Johnson LR, editor. Physiology of the gastrointestinal tract. New York: Raven Press; 1994. p. 381-422.
  • Costa M, Brookes SJ. The enteric nervous system. Am J Gastroenterol 1994;89:Suppl:S129-37.
  • Kunze WAA, Fumess JB. The enteric nervous system and regulation of intestinal motility. Annu Rev Physiol 1999;61:117-42.
  • Cooke HJ. Neuroimmune signaling in regulation of intestinal ion transport. Am J Physiol 1994;266:G167-78.
  • Surprenant A. Control of the gastrointestinal tract by enteric neurons. Annu Rev Physiol 1994;56:117-40.
  • Grundy D. The intestinal mucosa as a target and trigger for enteric reflexes. Gut 2000; Suppl IV 47:44-5.
  • Fumess JB, Kunze WA, Clerc N. Nutrient tasting and signaling mechanisms in the gut. II. The intestines as a sensory organ: neural, endocrine, and immune responses. Am J Physiol 1999; 277:G922-8.
  • Downing JE, Mijan JA. Neural immunoregulation: emerging roles for nerves in immune homeostasis and disease. Immunol Today 2000;21:281-9.
  • Davies AM. Role of neurotrophins in the developing nervous system. J Neurobiol 1994;25:1334-48.
  • Gershon MD. Genes and lineages in the formation of the enteric nervous system. Curr Opin Neurobiol 1997;7:101-9.
  • Hoehner JC, Wester T, Pahlman S, Olsen L. Localization of neurotrophins and their high affinity receptor during human enteric nervous system development. Gastroenterology 1996; 110:756-67.
  • Thoenen H. Neurotrophins and neuronal plasticity. Science 1995;270:593-8.
  • Lewin GR, Barde YA. The physiology of neurotrophins. Annu Rev Neurosci 1996;19:289-317.
  • Aloe L, Simone MD, Properzi F. Nerve growth factor: a neurotrophin with activity on cells of the immune system. Microsc Res Tech 1999;45:285-91.
  • Bonini S, Lambiase A, Levi-Schaffer F, Aloe L. Nerve growth factor: an important molecule in allergic inflammation and tissue remodelling. Int Arch Allergy Immunol 1999;118:159-62.
  • Hammarberg H, Lidman O, Lundberg C, Eltayeb SY, Gielen AW, Muhallab S, et al. Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells. J Neurosci 2000;20:5283-91.
  • Reinshagen M, Rohm H, Steinkamp M, Lieb K, Geerling I, Von Herbay A, et al. Protective role of neurotrophins in experimental inflammation of the rat gut. Gastroenterology 2000;119:368-76.
  • Togias A. Unique mechanistic features of allergic rhinitis. J Allergy Clin Immunol 2000;105:599-604.
  • Sanico AM, Stanisz AM, Gleeson TD, Bora S, Proud D, Bienenstock J, et al. Nerve growth factor expression and release in allergic inflammatory disease of the upper airways. Am J Respir Crit Care Med 2000;161:1631-5.
  • Braun A, Quarcoo D, Schulte-Herbrugge n O, Lommatzsch M, Hoyle G, Renz H. Nerve growth factor induces airway hyperresponsivenes s in mice. Int Arch Allergy Immunol 2001; 24:205-7.
  • Watanabe M, Endo Y, Kimoto K, Katoh-Semba R, Arakawa Y. Functional regulation of tactile sense by brain-derived neurotrophic factor in adult rats during acute inflammation. Neuroscience 2000;97:171-5.
  • Jaggar SI, Scott HC, Rice AS. Inflammation of the rat urinary bladder is associated with a referred thermal hyperalgesia, which is nerve growth factor dependent. Br J Anaesth 1999;83:442-8.
  • Soilu-Hanninen M, Epa R, Shipham K, Butzkueven H, Bucci T, Barrett G, et al. Treatment of experimental autoimmune encephalomyelitis with antisense oligonucleotides against the low affinity neurotrophin receptor. J Neurosci Res 2000;59:712-21.
  • Stanisz AM, Stanisz JA. Nerve growth factor and neuroimmune interactions in inflammatory diseases. Ann NY Acad Sci 2000; 917:268-72.
  • Di MoIa FF, Friess H, Zhu ZW, Koliopanos A, Bley T, Di Sebastiano P, et al. Nerve growth factor and Trk high affinity receptor (TrkA) gene expression in inflammatory bowel disease. Gut 2000;46:670-8.
  • Castagliuolo I, LaMont JT, Letoumeau R, Kelly C, O'Keane JC, Jaffer A, et al. Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum. Gastroenterology 1994;107:657-65.
  • Goyal RK, Hirano I. The enteric nervous system. N Engl J Med 1996;334:1106-14.
  • Pascual DW, Kiyono H, McGhee JR. The enteric nervous and immune systems: interactions for mucosal immunity and inflammation. Immunomethods 1994;5:56-72.
  • Holzer P, Wachter C, Heinemann A, Jocic M, Lippe IT, Herbert MK. Sensory nerves, nitric oxide and NANC vasodilatation. Arch Int Pharmacodyn Ther 1995;329:67-79.
  • Lindsay RM, Harmar AJ. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature 1989;337:362-64.
  • Reinshagen M, Flamig G, Ernst S, Geerling I, Wong H, Walsh JH, et al. Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonie injury. J Pharmacol Exp Ther 1998;286:657-61.
  • Reinshagen M, Patel A, Sottili M, Nast C, Davis W, Mueller K, et al. Protective function of extrinsic sensory neurons in acute rabbit experimental colitis. Gastroenterology 1994;106:1208-14.
  • Reinshagen M, Patel A, Sottili M, French S, Sternini C, Eysselein VE. Action of sensory neurons in an experimental rat colitis model of injury and repair. Am J Physiol 1996;270:G79-86.
  • Santambrogio L, Benedetti M, Chao MV, Muzaffar R, Kulig K, Gabellini N, et al. Nerve growth factor production by lymphocytes. J Immunol 1994;153:4488-95.
  • Torcia M, Bracci-Laudiero L, Lucibello M, Nencioni L, Labardi D, Rubartelli A, et al. Nerve growth factor is an autocrine survival factor for memory B lymphocytes. Cell 1996;85:345-56.
  • Leon A, Buriani A, DaI Toso R, Fabris M, Romanello S, Aloe L, et al. Mast cells synthesize, store, and release nerve growth factor. Proc Natl Acad Sci USA 1994;91:3739-43.
  • Levi Montalcini R, Skaper SD, DaI Toso R, Petrelli L, Leon A. Nerve growth factor: from neurotrophin to neurokine. Trends Neurosci 1996;19:514-20.
  • Asakura K, Hunter SF, Rodriguez M. Effects of transforming growth factor-beta and platelet-derived growth factor on oligodendrocyte precursors: insights gained from a neural cell line. J Neurochem 1997;68:2281-90.
  • Tuszynski MH, Weidner N, McCormack M, Miller I, Powell H, Conner J. Grafts of genetically modified Schwann cells to the spinal cord: survival, axon growth and myelination. Cell Transplant 1998;7:187-96.
  • Krobert K, Lopez-Colberg I, Cunningham LA. Astrocytes promote or impair the survival and function of embryonic ventral mesencephalon co-grafts: effects of astrocyte age and expression of recombinant brain-derived neurotrophic factor. Exp Neurol 1997;145:511-23.
  • Kobayashi H, Yamataka A, Fujimoto T, Lane GJ, Miyano T. Mast cells and gut nerve development: implications for Hirschsprung's disease and intestinal neuronal dysplasia. J Pediatr Surg 1999;34:543-8.
  • Getchell ML, Kulkami-Narla A, Takami S, Albers KM, Getchell TV. Age-dependent phenotypic switching of mast cells in NGFtransgenic mice. Neuroreport 1995;6:1261-6.
  • Marshall JS, Stead RH, McSharry C, Nielsen L, Bienenstock J. The role of mast cell degranulatio n products in mast cell hyperplasia. I. Mechanism of action of nerve growth factor. J Immunol 1990;144:1886-92.
  • Knutson L, Ahrenstedt O, Odlind B, Hallgren R. The jejunal secretion of histamine is increased in active Crohn's disease. Gastroenterology 1990;98:849-54.
  • Jiang W, Kreis ME, Eastwood C, Kirkup AJ, Humphrey PPA, Grundy D. 5-HT3 and histamine HI receptors mediate afferent nerve sensitivity to intestinal anaphylaxis in rats. Gastroenterology 2000;119:1267-75.
  • Fox CC, Lazenby AJ, Moore WC, Yardley JH, Bayless TM, Lichtenstein LM. Enhancement of human intestinal mast cell mediator release in active ulcerative colitis. Gastroenterology 1990;99:110-24.
  • Sanovic S, Lamb DP, Bleimerhassett MG. Damage to the enteric nervous system in experimental colitis. Am J Palhol 1999;155: 1051-7.
  • Collins SM, Vallance B, Barbara G, Borgaonkar M. Putative inflammatory and immunological mechanisms in functional bowel disorders. Baillieres Best Pract Res Clin Gastroenterol 1999;13:429-36.
  • Bush TG, Savidge TC, Freeman TC, Cox HJ, Campbell EA, Mucke L, et al. Fulminant jejuno-ileiti s following ablation of enteric glia in adult transgenic mice. Cell 1998;93:189-201.
  • Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205.
  • Brown DR, O'Grady SM. Regulation of ion transport in the porcine intestinal tract by enteric neurotransmitters and hormones. Comp Biochem Physiol A Physiol 1997;118:309-17.
  • Pacha J. Development of intestinal transport function in mammals. Physiol Rev 2000;80:1633-67.
  • Bar KJ, Facer P, Williams NS, Tarn PKH, Anand P. Glial-derived neurotrophic factor in human adult and fetal intestine and in Hirschsprung's disease. Gastroenterology 1997;112:1381-5.
  • Casaccia-Bonnefil P, Carter BD, Dobrowsky RT, Chao MV. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 1996;24:716-9.
  • Salehi AH, Roux PP, Kubu CJ, Zeindler C, Bhakar A, Tannis LL, et al. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factordependent apoptosis. Neuron 2000;27:279-88.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.