Postoperative on‐line monitoring with intraperitoneal microdialysis is a sensitive clinical method for measuring increased anaerobic metabolism that correlates to the cytokine response

References

• Landow L, Andersen LW. Splanchnic ischaemia and its role in multiple organ failure. Acta Anaesthesiol Scand 1994;38:626–39.
   PubMed Web of Science ®Google Scholar
• Tamion F, Richard V, Lyoumi S, Daveau M, Bonmarchand G, Leroy J, et al. Gut ischemia and mesenteric synthesis of inflammatory cytokines after hemorrhagic or endotoxic shock. Am J Physiol 1997;273 (2Pt 1):G314–21.
   Google Scholar
• Fiddian-Green RG. Splanchnic ischaemia and multiple organ failure in the critically ill. Ann R Coll Surg Engl 1988;70:128–34.
   PubMed Web of Science ®Google Scholar
• Jansson K, Redler B, Truedsson L, Magnuson A, Matthiessen P, Andersson M, et al. Intraperitoneal cytokine response after major surgery. Am J Surg 2003.
   Google Scholar
• Schein M, Wittmann DH, Holzheimer, Condon RE. Hypothesis: compartmentalization of cytokines in intraabdominal infection. Surgery 1996;119:694–700.
   PubMed Web of Science ®Google Scholar
• Dinarello CA. Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol 1996;216:133–65.
   PubMedGoogle Scholar
• Esmon CT. Possible involvement of cytokines in diffuse intravascular coagulation and thrombosis. Baillieres Best Pract Res Clin Haematol 1999;12:343–59.
   PubMed Web of Science ®Google Scholar
• McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985;312:159–63.
   PubMed Web of Science ®Google Scholar
• Gutierrez G, Palizas F, Doglio G. Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 1992;339 (8787):195–9.
   Google Scholar
• Ungerstedt J, Ericzon BG, Ungerstedt U. Intraperitoneal microdialysis (IPM)-a new technique for monitoring intestinal ischemia studied in a porcine model. Shock 2003;20:91–6.
   Google Scholar
• Jansson K, Jonsson T, Norgren L. Intraperitoneal microdialysis (IPM) a new method to monitor patients after abdominal surgery. Int J Intensive Care 2003;10:8–13.
   Google Scholar
• Jansson K, Ungerstedt J, Redler B, Andersson M, Ungerstedt U, Norgren L. Human intraperitoneal microdialysis—increased lactate/pyruvate ratio suggests early visceral ischemia: a pilot study. Scand J Gastroenterol 2003;38:1007–11.
   PubMed Web of Science ®Google Scholar
• van Berge Henegouwen MI, van der Poll T, van Deventer SJ, Gouma DJ. Peritoneal cytokine release after elective gastrointestinal surgery and postoperative complications. Am J Surg 1998;175:311–6.
   PubMed Web of Science ®Google Scholar
• Scheingraber S, Bauerfeind F, Bohme J, Dralle H. Limits of peritoneal cytokine measurements during abdominal lavage treatment for intraabdominal sepsis. Am J Surg 2001;181:301–8.
   PubMedGoogle Scholar
• Goris RJ, Boekholtz WK, van Bebber IP, Nuytinck JK, Schillings PH. Multiple-organ failure and sepsis without bacteria. An experimental model. Arch Surg 1986;121:897–901.
   Google Scholar
• Swank GM, Deitch EA. Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg 1996;20:411–7.
   PubMed Web of Science ®Google Scholar
• Moore KW, de Waal Malefyt R, Coffman RL, O’Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 2001;19: 683–765.
   Google Scholar
• Rongione AJ, Kusske AM, Kwan K, Ashley SW, Reber HA, McFadden DW. Interleukin-10 protects against lethality of intraabdominal infection and sepsis. J Gastrointest Surg 2000;4:70–6.
   PubMedGoogle Scholar
• Van Laethem JL, Marchant A, Delvaux A. Interleukin 10 prevents necrosis in murine experimental acute pancreatitis. Gastroenterology 1995;108: 1917–22.
   Google Scholar
• Kusske AM, Rongione AJ, Ashley SW, McFadden DW, Reber HA. Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice. Surgery 1996;120:284–8 discussion 289.
   Google Scholar
• Deviere J, Le Moine O, Van Laethem JL. Interleukin 10 reduces the incidence of pancreatitis after therapeutic endoscopic retrograde cholangiopancreatography. Gastroenterology 2001; 120: 498–505.
   PubMed Web of Science ®Google Scholar
• Dumot JA, Conwell DL, Zuccaro G, Jr. A randomized, double blind study of interleukin 10 for the prevention of ERCP-induced pancreatitis. Am J Gastroenterol 2001;96:2098–102.
   PubMedGoogle Scholar
• Remick DG, Garg SJ, Newcomb DE, Wollenberg G, Huie TK, Bolgos GL. Exogenous interleukin-10 fails to decrease the mortality or morbidity of sepsis. Crit Care Med 1998; 26: 895–904.
   PubMed Web of Science ®Google Scholar
• Kato T, Murata A, Ishida H. Interleukin 10 reduces mortality from severe peritonitis in mice. Antimicrob Agents Chemother 1995;39: 1336–40.
   Google Scholar
• Haglund U, Fiddian-Green RG. Assessment of adequate tissue oxygenation in shock and critical illness: oxygen transport in sepsis, Bermuda, April 1 + 2,1989 Intensive Care Med 1989;15: 475–7.
   Google Scholar
• Huckabee WE. Hypoxia and lactate formation. Hoppe Seylers Z Physiol Chem 1970;351:280–1.
   PubMedGoogle Scholar
• Huckabee WE. Hyperlactatemia. Helv Med Acta 1970;35:363–76.
   PubMedGoogle Scholar
• Ungerstedt U. Microdialysis—principles and applications for studies in animals and man. J Intern Med 1991;230:365–73.
   PubMedGoogle Scholar
• Nowak G, Ungerstedt J, Wernerman J, Ungerstedt U, Ericzon BG. Clinical experience in continuous graft monitoring with microdialysis early after liver transplantation. Br J Surg 2002;89: 1169–75.
   Google Scholar
• Mendelowitsch A. Microdialysis: intraoperative posttraumatic applications. Neurosurgery Methods 2001. p. 2373–81.
   Google Scholar
• Reinstrup P, Stahl N, Mellergard P, Uski T, Ungerstedt U, Nordstrom CH. Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia and neurosurgery. Neurosurgery 2000;47:701–9.
   PubMed Web of Science ®Google Scholar