Polyamine biosynthesis in relation to K‐ras and p‐53 mutations in colorectal carcinoma

References

• Pegg AE. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res 1988;48: 759–74.
   PubMed Web of Science ®Google Scholar
• Milovic V, Turchanowa L. Polyamines and colon cancer. Biochem Soc Trans 2003;31:381–3.
   PubMed Web of Science ®Google Scholar
• Thomas T, Thomas TJ. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 2001;58:244–58.
   PubMed Web of Science ®Google Scholar
• Kubata S, Kiyosawa H, Nomura Y, Yamada T, Seyama Y. Ornithine decarboxylase overexpression in mouse 10t1/2 fibroblast cellular transformation and invasion. J Natl Cancer Inst 1997;89: 567–71.
   Google Scholar
• Srivastava S, Verma M, Henson DE. Biomarkers for early detection of colon cancer. Clin Cancer Res 2001;7:1118–26.
   PubMed Web of Science ®Google Scholar
• Harris C, Hollstein M. Clinical implications of the p53 tumor suppressor gene. N Engl J Med 1993;329:1318–27.
   PubMed Web of Science ®Google Scholar
• Patel AR, Wang JY. Polyamines modulate transcription but not posttranscription of c-myc and c-jun in IEC-6 cells. Am J Physiol 1997;273:C1020–9.
   PubMed Web of Science ®Google Scholar
• Tabib A, Bachrach U. Role of polyamines in mediating malignant transformation and oncogene expression. Int J Biochem Cell Biol 1999;31:1289–95.
   PubMed Web of Science ®Google Scholar
• Smith MK, Trempus CS, Gilmour SK. Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. Carcinogenesis 1998;19:1409–15.
   Google Scholar
• Shantz LM, Pegg AE. Ornithine decarboxylase induction in transformation by H-Ras and RhoA. Cancer Res 1998;58:2748–53.
   PubMed Web of Science ®Google Scholar
• Lan L, Trempus C, Gilmour SK. Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in Odc/Ras transgenic mice. Cancer Res 2000;60:5696–703.
   Google Scholar
• Li L, Li J, Rao JN, Li M, Bass BL, Wang J-Y. Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis. Am J Physiol 1999;276:C946–54.
   Google Scholar
• Nemoto T, Kamei S, Seyama Y, Kubota S. p53 independent G(1) arrest induced by DL-alpha-difluoromethylornithine. Biochem Biophys Res Commun 2001;280:848–54.
   PubMed Web of Science ®Google Scholar
• Lawson KR, Ignatenko NA, Piazza GA, Cui H, Gerner EW. Influence of K-ras activation on the survival response of caco-2 cells to the chemopreventive agents sulindac and difluoromethy- lornithine. Cancer Epidemiol Biomarkers Prev 2000;11: 1155–62.
   Google Scholar
• Singh J, Reddy BS. Molecular markers in chemoprevention of colon cancer. Inhibition of expression of ras-p21 and p53 by sulindac during azoxymethane-induced colon carcinogenesis. Ann NY Acad Sci 1995;768:205–9.
   Google Scholar
• Wallace HM, Fraser AV. Polyamine analogues as anticancer drugs. Biochem Soc Trans 2003;31:393–6.
   PubMed Web of Science ®Google Scholar
• Linsalata M, Caruso MG, Leo S, Guerra V, D’Attoma B, Di Leo A. Prognostic value of tissue polyamine levels in human colorectal carcinoma. Anticancer Res 2002;22:2465–70.
   Google Scholar
• Notarnicola M, Cavallini A, Cardone R, Pezzolla F, Demma I, Di Leo A. K-ras and p53 mutations in DNA extracted from colonic epithelial cells exfoliated in faeces of patients with colorectal cancer. Digest Liver Dis 2000;32: 131–6.
   Google Scholar
• Russo F, Linsalata M, Messa C, Cavallini A, Notarnicola M, Guerra V, et al. Polyamines and estrogen receptor concentrations in human colorectal carcinomas. Ital J Gastroenterol 1992;24:8–12.
   PubMedGoogle Scholar
• Di Leo A, Linsalata M, Cavallini A, Messa C, Russo F. Sex steroid hormone receptors, epidermal growth factor receptor, and polyamines in human colorectal cancer. Dis Colon Rectum 1992; 35:305–9.
   Google Scholar
• Linsalata M, Russo F, Cavallini A, Berloco P, Di Leo A. Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa. Dis Colon Rectum 1993;36:662–7.
   Google Scholar
• Notarnicola M, Linsalata M, Caruso MG, Cavallini A, Di Leo A. Low density lipoprotein receptors and polyamine levels in human colorectal adenocarcinoma. J Gastroenterol 1995; 30: 705–9.
   Google Scholar
• Linsalata M, Cavallini A, Di Leo A. Polyamine oxidase activity and polyamine levels in human colorectal cancer and in normal surrounding mucosa. Anticancer Res 1997;17:3757–60.
   Google Scholar
• Porter CW, Herrera-Ornela L, Pera P, Petrelli NF, Mittelman A. Polyamine biosynthetic activity in normal and neoplastic human colorectal tissue. Cancer 1987;60:1275–81.
   PubMed Web of Science ®Google Scholar
• Wallace HM, Caslake R. Polyamine and colon cancer. Eur J Gastroenterol Hepatol 2001;13:1033–9.
   PubMed Web of Science ®Google Scholar
• Linsalata M, Messa C, Russo F, Cavallini A, Di Leo A. Oestrogen receptors and polyamine levels in human gastric carcinoma. Scand J Gastroenterol 1994;29:67–70.
   Google Scholar
• Russo F, Linsalata M, Giorgio I, Caruso ML, Armentano R, Di Leo A. Polyamine levels and ODC activity in intestinal-type and diffuse-type gastric carcinoma. Dig Dis Sci 1997;42:576–9.
   Google Scholar
• Loser C, Folsch UR, Paprotny C, Creutzfeldt W. Polyamines in human gastric and oesophageal cancer. Scand J Gastroenterol 1989;24:1193–9.
   PubMed Web of Science ®Google Scholar
• Auvinen M, Paasinen A, Andersson LC, Holtta E. Ornithine decarboxylase activity is critical for cell transformation. Nature 1992;360:355–7.
   PubMed Web of Science ®Google Scholar
• Loser C, Folsch UR, Paprotny C, Creutzfeldt W. Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer. Cancer 1990;65: 958–66.
   Google Scholar
• Kingsnorth AN, Lumsden AB, Wallace HM. Polyamines in colorectal cancer. Br J Surg 1984;71:791–4.
   Google Scholar
• Weiss Bernhardt G, Buschauer A, Thasler WE, Dolgner D, Zirngibl I, Jauch KW. Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade. Int J Colorectal Dis 2002;17:381–7.
   PubMed Web of Science ®Google Scholar
• Watanabe T, Muto T. Colorectal carcinogenesis based on molecular biology of early colorectal cancer, with special reference to nonpolypoid (superficial) lesion. World J Surg 2000;24:1091–7.
   PubMed Web of Science ®Google Scholar
• Caruso MG, Notarnicola M, Bifulco M, Laezza C, Guerra V, Altomare DF, et al. Increased farnesyltransferase activity in human colorectal cancer: relationship with clinicopathological features and K-ras mutation. Scand J Gastroenterol 2003; 38: 80–5.
   PubMed Web of Science ®Google Scholar
• Hurta Ra, Lee J, Voskas D. Transformation by H-ras can result in aberrant regulation of ornithine decarboxylase gene expression by transforming growth factor-beta. J Cell Biochem 2001;81:39–55.
   Google Scholar
• Sarfati P, Dubé M, Pradayrol L, Morisset J. Increases in Ki-ras and ornithine decarboxylase gene expression in rat pancreas after caerulein-induced pancreatitis. Digestion 1996;57:453–63.
   PubMed Web of Science ®Google Scholar
• Hölttä E, Sistonen L, Alitalo K. The mechanism of ornithine decarboxylase deregulation in c-Ha-ras oncogene-transformed NIH 3T3 cells. J Biol Chem 1988;263: 4500–7.
   Google Scholar
• Shayovitis A, Bachrach U. Ornithine decarboxylase: an indicator for growth of NIH 3T3 fibroblast and their c-Ha-ras transformants. Biochim Biophys Acta 1995;1267:107–14.
   PubMed Web of Science ®Google Scholar
• Auvinen M. Cell transformation, invasion, and angiogenesis: a regulatory role for ornithine decarboxylase and polyamines? J Natl Cancer Inst 1997;89:533–7.
   PubMedGoogle Scholar
• Li L, Rao JN, Guo X, Liu L, Santora R, Bass BL, et al. Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation. Am J Physiol Cell Physiol 2001;281:C941–53.
   PubMed Web of Science ®Google Scholar
• Ray RM, McCormack SA, Johnson LR. Polyamine depletion arrests growth of IEC-6 and Caco-2 cells by different mechanisms. Am J Physiol Gastrointest Liver Physiol 2001;281:G37–43.
   Google Scholar
• Elitsur Y, Koh SJ, Moshier JA, Dosescu J, Tureaud J, Majumdar AP. Ornithine decarboxylase and tyrosine kinase activity in juvenile polyps of childhood. Pediatr Res 1995;38:574–8.
   PubMed Web of Science ®Google Scholar
• Notarnicola M, Linsalata M, Caruso MG, Caruso ML, Altomare D, Lorusso D, et al. Genetic and biochemical changes in colorectal carcinoma in relation to morphologic characteristics. Oncol Rep 2003;10:1987–91.
   PubMed Web of Science ®Google Scholar
• Hahm HA, Dunn VR, Kimberly AB, Deveraux WL, Woster PM, Casero RA, et al. Combination of standard cytotoxic agents with polyamine analogues in the treatment of breast cancer cell lines. Clin Cancer Res 2001;7:391–9.
   PubMed Web of Science ®Google Scholar