Geranylgeranylacetone protects mice from dextran sulfate sodium-induced colitis

References

• Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417–29
   PubMed Web of Science ®Google Scholar
• Sartor, RB. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am J Gastroenterol 1997;92(Suppl 12): 5S–11S.
   Web of Science ®Google Scholar
• Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu Rev Med 2000; 51: 289–98
   PubMed Web of Science ®Google Scholar
• de Jong YP, Abadia-Molina AC, Satoskar AR, Clarke K, Rietdijk ST, Faubion WA, et al. Development of chronic colitis is dependent on the cytokine MIF. Nat Immunol 2001; 2: 1061–6
   PubMed Web of Science ®Google Scholar
• Ohkawara T, Nishihira J, Takeda H, Hige S, Kato M, Sugiyama T, et al. Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology 2002; 123: 256–70
   PubMed Web of Science ®Google Scholar
• van Dullemen HM, van Deventer SJ, Hommes DW, Bijl HA, Jansen J, Tytgat GN, et al. Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 1995; 109: 129–35
   PubMed Web of Science ®Google Scholar
• Targan SR, Hanauer SB, van Deventer SJ, Mayer L, Present DH, Braakman T, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997; 337: 1029–35
   PubMed Web of Science ®Google Scholar
• Bickston SJ, Lichtenstein GR, Arseneau KO, Cohen RB, Cominelli F. The relationship between infliximab treatment and lymphoma in Crohn's disease. Gastroenterology 1999; 117: 1433–7
   PubMed Web of Science ®Google Scholar
• Keane J, Gershon S, Wise RP, Mirabile-Levens E, Kasznica J, Schwieterman WD, et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 2001; 345: 1098–104
   PubMed Web of Science ®Google Scholar
• Pockley AG. Heat shock protein as regulators of the immune response. Lancet 2003; 362: 469–76
   PubMed Web of Science ®Google Scholar
• Nakamura K, Rokutan K, Marui N, Aoike A, Kawai K. Induction of heat shock proteins and their implication in protection against ethanol-induced damage in cultured guinea pig gastric mucosal cells. Gastroenterology 1991; 101: 161–6
   PubMed Web of Science ®Google Scholar
• Mestril R, Chi SH, Sayen MR, O'Reilly K, Dillmann WH. Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against stimulated ischemia-induced injury. J Clin Invest 1994; 93: 759–67
   PubMed Web of Science ®Google Scholar
• Fujimori S, Otaka M, Otani S, Jin M, Okuyama A, Itoh S, et al. Induction of a 72-kDa heat shock protein and cytoprotection against thioacetamide-induced liver injury in rats. Dig Dis Sci 1997; 42: 1987–94
   PubMed Web of Science ®Google Scholar
• Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest 1995; 95: 1446–56
   PubMed Web of Science ®Google Scholar
• Hutter JJ, Mestril R, Tam EK, Sievers RE, Dillmann WH, Wolfe CL. Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo. Circulation 1996; 94: 1408–11
   PubMed Web of Science ®Google Scholar
• Ludwig D, Stahl M, Ibrahim ET, Wenzel BE, Drabicki D, Wecke A, et al. Enhanced intestinal expression of heat shock protein 70 in patients with inflammatory bowel disease. Dig Dis Sci 1999; 44: 1440–7
   PubMed Web of Science ®Google Scholar
• Terano A, Shiga J, Hiraishi H, Ota S, Sugimoto T. Protective action of tetraprenylacetone against ethanol-induced damage in rat gastric mucosa. Digestion 1986; 35: 182–8
   PubMed Web of Science ®Google Scholar
• Pappas TN, Mulvihill SJ, Goto Y, Debas HT. Advances in drug therapy for peptic ulcer disease. Arch Surg 1987; 122: 447–50
   PubMedGoogle Scholar
• Bilski J, Sarosiek J, Murty VL, Aono M, Moriga M, Slomiany A, et al. Enhancement of the lipid content and physical properties of gastric mucus by geranylgeranylacetone. Biochem Pharmacol 1987; 36: 4059–65
   PubMed Web of Science ®Google Scholar
• Fujimoto M, Yamanaka T, Bessho M, Igarashi T. Effects of geranylgeranylacetone on gastrointestinal secretion. Eur J Pharmacol 1982; 77: 113–8
   PubMed Web of Science ®Google Scholar
• Ito M, Tanaka T, Suzuki Y. Increasing action of teprenone, a new antiulcer agent, on high-molecular-weight glycoprotein in gastric mucus during the healing process of acetic acid-induced ulcer in rats. Jpn J Pharmacol 1986; 41: 117–25
   PubMedGoogle Scholar
• Hirakawa T, Rokutan K, Nikawa T, Kishi K. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology 1996; 111: 325–37
   PubMed Web of Science ®Google Scholar
• Yamagami K, Yamamoto Y, Ishikawa Y, Yonezawa K, Toyokuni S, Yamaoka Y. Effects of geranyl-geranyl-acetone administration before heat shock preconditioning for conferring tolerance against ischemia-reperfusion injury in rat livers. J Lab Clin Med 2000; 135: 465–75
   PubMed Web of Science ®Google Scholar
• Ooie T, Takahashi N, Saikawa T, Nawata T, Arikawa M, Yamanaka K, et al. Single oral dose of geranylgeranylacetone induces heat-shock protein 72 and renders protection against ischemia/reperfusion injury in rat heart. Circulation 2001; 104: 1837–43
   PubMed Web of Science ®Google Scholar
• Unoshima M, Iwasaka H, Eto J, Takita-Sonoda Y, Noguchi T, Nishizono A. Antiviral effects of geranylgeranylacetone: enhancement of MxA expression and phosphorylation of PKR during influenza virus infection. Antimicrob Agents Chemother 2003; 47: 2914–21
   PubMed Web of Science ®Google Scholar
• Cooper HS, Murthy SN, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993; 69: 238–49
   PubMed Web of Science ®Google Scholar
• Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344–50
   PubMed Web of Science ®Google Scholar
• Benjamin IJ, McMIllan DR. Stress (heat shock) proteins molecular chaperones. Circ Res ;;83 1998; 27: 117–32
   Web of Science ®Google Scholar
• Baca-Estrada ME, Gupta RS, Stead RH, Croitoru K. Intestinal expression and cellular immune responses to human heat-shock protein 60 in Crohn's disease. Dig Dis Sci 1994; 39: 498–506
   PubMed Web of Science ®Google Scholar
• Stahl M, Ludwig D, Fellermann K, Stange EF. Intestinal expression of human heat shock protein 90 in patients with Crohn's disease and ulcerative colitis. Dig Dis Sci 1998; 43: 1079–87
   PubMed Web of Science ®Google Scholar
• Oda H, Miyake H, Iwata T, Kusumoto K, Rokutan K, Tashiro S. Geranylgeranylacetone suppresses inflammatory responses and improves survival after massive hepatectomy in rats. J Gastrointest Surg 2002; 6: 464–73
   PubMed Web of Science ®Google Scholar
• Tsuruma T, Yagihashi A, Koide S, Araya J, Tarumi K, Watanabe N, et al. Geranylgeranylacetone induces heat shock protein-73 in rat small intestine. Transplant Proc 1999; 31: 572–3
   PubMed Web of Science ®Google Scholar
• Venkatraman A, Ramakrishna BS, Shaji RV, Nanda Kumar NS, Pulimood A, Patra S. Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-κB. Am J Physiol Gastrointest Liver Physiol 2003; 285: G177–84
   Web of Science ®Google Scholar
• Van Molle W, Wielockx B, Mahieu T, Takada M, Taniguchi T, Sekikawa K, et al. HSP70 protects against TNF-induced lethal inflammatory shock. Immunity 2002; 16: 685–95
   PubMed Web of Science ®Google Scholar
• Kojima K, Musch MW, Ren H, Boone DL, Hendrickson BA, Ma A, et al. Enteric flora and lymphocyte-derived cytokines determine expression of heat shock proteins in mouse colonic epithelial cells. Gastroenterology 2003; 124: 1395–407
   PubMed Web of Science ®Google Scholar
• Otani S, Otaka M, Jin M, Okuyama A, Itoh S, Iwabuchi A, et al. Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats. Dig Dis Sci 1997; 42: 833–46
   PubMed Web of Science ®Google Scholar
• Urayama S, Musch MW, Retsky J, Madonna MB, Straus D, Chang EB. Dexamethasone protection of rat IEC against oxidant injury mediated by induction of heat shock protein 72. J Clin Invest 1998; 102: 1860–5
   PubMed Web of Science ®Google Scholar
• Burress GC, Musch MW, Jurivich DA, Welk J, Chang EB. Effects of mesalamine on the hsp72 stress response in rat IEC-18 intestinal epithelial cells. Gastroenterology 1997; 113: 1474–9
   PubMed Web of Science ®Google Scholar