158
Views
23
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells

, , , , , , , & , MD show all
Pages 1454-1461 | Received 22 Nov 2004, Published online: 08 Jul 2009

References

  • Mehta N, Hordines J, Volpe C, Doerr R, Cohen SA. Cellular effects of hypercholesterolemia in modulation of cancer growth and metastasis: a review of evidence. Surg Oncol 1997; 7: 179–86
  • Rao KN. The significance of the cholesterol biosynthetic pathway in cell growth and carcinogenesis [review]. Anticancer Res 1995; 15: 309–14
  • Coleman PS, Laviets BB. Membrane cholesterol and tumorigenesis. CRC Crit Rev Biochem 1981; 11: 341–93
  • Caruso MG, Osella AR, Notarnicola M, Berloco P, Leo S, Bonfiglio C, et al. Prognostic value of low density lipoprotein receptor expression in colorectal carcinoma. Oncol Rep 1998; 5: 927–30
  • Caruso MG, Notarnicola M, Santillo M, Cavallini A, Di Leo A. Enhanced 3-hydroxy-3-methyl-glutaryl coenzyme A reductase activity in human colorectal cancer not expressing low density lipoprotein receptor. Anticancer Res 1999; 19: 451–4
  • Rao KN, Elm MS, Kelly RH, Chandar N, Brady EP, Rao B, et al. Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth. Gastroenterology 1997; 113: 238–48
  • Fabricant M, Broitman SA. Evidence for deficiency of low density lipoprotein receptor on human colonic carcinoma cell lines. Cancer Res 1990; 50: 632–6
  • Di Croce L, Bruscalupi G, Trentalance A. Independent behavior of rat liver LDL receptor and HMGCoA reductase under estrogen treatment. Biochem Biophys Res Comm 1996; 224: 345–50
  • Di Stefano E, Marino M, Gillette JA, Hanstein B, Pallottini V, Bruning J, et al. Role of tyrosine kinase signaling in estrogen-induced LDL receptor gene expression in HepG2 cells. Biochim Biophys Acta 2002; 1580: 145–9
  • Borradaile NM, De Dreu LE, Wilcox LJ, Edwards JY, Huff MW. Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms. Biochem J 2002; 366: 531–9
  • Di Leo A, Messa C, Cavallini A, Linsalata M. Estrogens and colorectal cancer. Current Drug Targets-Immune. Endocr Metab Dis 2001; 1: 1–12
  • Grondstein F, Newcomb PA, Stampler MJ. Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis. Am J Med 1999; 106: 574–83
  • Al-Azzawi F, Wahab M. Estrogen and colon cancer: current issues. Climateric 2002; 5: 3–14
  • Xu X, Thomas ML. Estrogen receptor-mediated direct stimulation of colon cancer cell growth in vitro. Mol Cell Endocrinol 1994; 105: 197–201
  • Singh S, Paraskeva C, Gallimore PH, Sheppard MC, Langman MJS. Differential growth response to oestrogen of premalignant and malignant colonic cell lines. Anticancer Res 1994; 14: 1037–42
  • Di Domenico M, Castoria G, Bilancio A, Migliaccio A, Auricchio F. Estradiol activation of human colon carcinoma-derived Caco-2 cell growth. Cancer Res 1996; 56: 4516–21
  • Di Leo A, Messa C, Russo F, Misciagna G, Guerra V, Taveri R, et al. Prognostic value of cytosolic estrogen receptors in human colorectal carcinoma and surrounding mucosa. Preliminary results. Dig Dis Sci 1994; 39: 2038–42
  • Russo F, Linsalata M, Messa C, Cavallini A, Notarnicola M, Guerra V, et al. Polyamines and estrogen-receptor concentrations in human colorectal carcinomas. Ital J Gastroenterol 1992; 24: 8–12
  • Messa C, Pricci M, Linsalata M, Russo F, Di Leo A. Inhibitory effect of 17β-estradiol on growth and the polyamine metabolism of a human gastric carcinoma cell line (HGC-27). Scand J Gastroenterol 1999; 34: 79–84
  • Messa C, Russo F, Pricci M, Di Leo A. Epidermal growth factor and 17β-estradiol effects on proliferation of a human gastric cancer cell lines (AGS). Scand J Gastroenterol 2000; 35: 753–8
  • Fiorelli G, Picariello V, Martinetti F, Tonelli F, Brandi ML. Functional estrogen receptor β in colon cancer cells. Biochem Biophys Res Commun 1999; 261: 521–7
  • Bocchetta M, Bruscalupi G, Castellano F, Trentalance A, Komaromy M, Fong LG, et al. Early induction of LDL receptor gene during rat liver regeneration. J Cell Physiol 1993; 156: 601–9
  • Lamon-Fava S, Ordovas JM, Schaefer EJ. Estrogen increases apolipoprotein (Apo) A-I in Hep G2 cells by modulating transcription of the apo A-I gene promoter. Arterioscler Thromb Vasc Biol 1999; 19: 2960–5
  • Lowry OH, Rosembrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • Caruso MG, Notarnicola M, Bifulco M, Laezza C, Guerra V, Altomare DF, et al. Increased farnesyltransferase activity in human colorectal cancer: relationship with clinicopathological features and K-ras mutation. Scand J Gastroenterol 2003; 38: 80–5
  • Siperstein MD. Role of cholesterogenesis and isoprenoid synthesis in DNA replication and cell growth. J Lipid Res 1984; 25: 1462–8
  • Clarke S. Protein isoprenylation and methylation at carboxyl-terminal cystein residue. Annu Rev Biochem 1992; 61: 355–86
  • Crowell PL. Prevention and therapy of cancer by dietary monoterpenes. J Nutr 1999; 129: 775S–8S
  • Crick DC, Andres DA, Danesi R, Macchia M, Waechter CJ. Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. J Neurochem 1998; 70: 2397–405
  • Castellano F, Bruscalupi G, Colomba S, Di Croce L, Trentalance A, Augusti-Tocco G. Characterisation of the response of growth and differentiation to lipoprotein and agents affecting cholesterol metabolism in murine neuroblastoma cells. Int J Dev Neurosci 1994; 12: 77–84
  • Marino M, Distefano E, Pallottini V, Caporali S, Bruscalupi G, Trentalance A. Activation of IP3-protein kinase C-α signal transduction pathway precedes the change of plasma cholesterol, hepatic lipid metabolism and induction of low-density lipoprotein receptor expression in 17-β-oestradiol-treated rats. Exp Physiol 2001; 86: 139–45
  • Gil G, Faust JR, Chin DJ, Goldstein JL, Brown MS. Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme. Cell 1985; 41: 249–58
  • Sever N, Song BL, Yabe D, Goldstein JL, Brown MS, DeBose-Boyd RA. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol. J Biol Chem 2003; 278: 52479–90
  • Notarnicola M, Messa C, Cavallini A, Bifulco M, Tecce MF, Eletto D, et al. Higher farnesyl diphosphate synthase activity in human colorectal cancer: inhibition of cellular apoptosis. Oncology 2004; 67: 351–8
  • Thibault A, Samid D, Tompkins AC, Figg WD, Cooper MR, Hohl RJ, et al. Phase I study of Lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. Clin Cancer Res 1996; 2: 483–91
  • Notarnicola M, Messa C, Pricci M, Guerra V, Altomare DF, Montemurro S, et al. Up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in left-sided human colon cancer. Anticancer Res 2004; 24: 3837–42

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.