1,618
Views
12
CrossRef citations to date
0
Altmetric
Original Article

Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome

, , , , ORCID Icon, , , & show all
Pages 537-542 | Received 04 Jan 2020, Accepted 06 Apr 2020, Published online: 24 Apr 2020

References

  • Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut. 1973;14(2):125–132.
  • Feng B, La JH, Schwartz ES, et al. Irritable bowel syndrome, mechanisms, and pathophysiology. Neural and neuro-immune mechanism of visceral hypersensitivity in irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2012;302(10):G1085–G1098.
  • Ford AC, Talley NJ. Mucosal inflammation as a potential etiological factor in irritable bowel syndrome: a systematic review. J Gastroenterol. 2011;46(4):421–431.
  • Bashashati M, Rezaei N, Andrews CN, et al. Cytokines and irritable bowel syndrome: where do we stand? Cytokine. 2012;57(2):201–209.
  • Hughes PA, Zola H, Penttila IA, et al. Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms? Am J Gastroenterol. 2013;108(7):1066–1074.
  • Vanner S, Greenwood-Van Meerveld G, Mawe GM, et al. Fundamentals of neurogastroenterology: basic science. Gastroenterology. 2016;150(6):1280–1291.
  • Boeckxstaens GE, Wouters MM. Neuroimmune factors in functional gastrointestinal disorders: a focus on irritable bowel syndrome. Neurogastroenterol Motil. 2017;29(6):e13007–e13010.
  • Collins SM. Is the irritable gut an inflamed gut? Scand J Gastroenterol. 1992;27(Suppl. 192):102–105.
  • Thompson JR. Is irritable bowel disease an infectious disease? World J Gastroenterol. 2016;22(4):1331–1334.
  • Spiller RC, Jenkins D, Thornley JP, et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut. 2000;47(6):804–811.
  • Barbara G, Cremon VC, Stanghellini V. Inflammatory bowel disease and irritable bowel syndrome: similarities and differences. Curr Opin Gastroenterol. 2014;30(4):352–358.
  • Spiller RC, Garsed K. Postinfectious irritable bowel syndrome. Gastroenterology. 2009;136(6):1979–1988.
  • Chadwick VS, Chen W, Shu D, et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology. 2002;122(7):1778–1783.
  • Cremon C, Gargano L, Morselli-Labate AM, et al. Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms. Am J Gastroenterol. 2009;104(2):392–400.
  • O’Sullivan MA, O’Morain C. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil. 2000;12:449–457.
  • Krammer L, Sowa AS, Lorentz A. Mast cells in irritable bowel syndrome: a systematic review. J Gastrointestin Liver Dis. 2019;28(4):463–472.
  • Barbara G, Stanghellini V, De Giorgio R, et al. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology. 2004;126(3):693–702.
  • Braak B, Klooker TK, Wouters MM, et al. Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome: is there any relationship? Am J Gastroenterol. 2012;107(5):715–726.
  • Gwee KA, Collins SM, Read NW, et al. Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome. Gut. 2003;52(4):523–526.
  • Bennet SM, Polster A, Tornblom H, et al. Global cytokine profiles and association with clinical characteristics in patients with irritable bowel syndrome. Am J Gastroenterol. 2011;111:1165–1176.
  • Chang L, Adeyemo M, Karagiannidis I, et al. Serum and colonic mucosal immune markers in irritable bowel syndrome. Am J Gastroenterol. 2012;107(2):262–272.
  • Macsharry J, O'Mahony L, Fanning A, et al. Mucosal cytokine imbalance in irritable bowel syndrome. Scand J Gastroenterol. 2008;43(12):1467–1476.
  • Chen J, Zhang Y, Deng Z. Imbalance shift of cytokine expression between T helper 1 and T helper 2 (TH1/TH2) in intestinal mucosa of patients with post-infectious irritable bowel disease. BMC Gastroenterol. 2012;12(1):91.
  • Mearin F, Perello A, Balboa A, et al. Pathogenetic mechanisms of postinfectious functional gastrointestinal disorders: results 3 years after gastroenteritis. Scand J Gastroenterol. 2009;44(10):1173–1185.
  • Wouters MM, Van Wanrooy S, Nguyen A, et al. Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis. Gut. 2016;65(8):1279–1288.
  • Berg LK, Fagerli E, Martinussen M, et al. Effect of fructose-reduced diet in patients with irritable bowel disease and its correlation to a standard fructose breath test. Scand J Gastroenterol. 2013;48(8):936–943.
  • Berg LK, Fagerli E, Myhre AO, et al. Self-reported dietary fructose intolerance in irritable bowel syndrome: proposed diagnostic criteria. World J Gastroenterol. 2015;21(18):5677–5684.
  • Florholmen J, Fries W. Candidate mucosal and surrogate predictive and prognostic biomarkers of inflammatory bowel disease in the era of new technology. Scand J Gastroenterol. 2011;46(12):1407–1417.
  • Soufli I, Toumi R, Rafa H, et al. Overview of cytokines and nitric oxide involvement in immuno-pathogenesis of inflammatory bowel diseases. World J Gastrointest Pharmacol Ther. 2016;7(3):353–360.
  • Dinan TG, Clarke G, Quigley EM, et al. Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors. Am J Gastroenterol. 2008;103(10):2570–2576.
  • Van de Veek PP, van den Berg M, de Kroon YE, et al. Role of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in irritable bowel disease. Am J Gastroenterol. 2005;100(11):2510–2516.
  • Wouters MM, Vicario M, Santos J. The role of mast cells in functional disorders. Gut. 2016;65(1):155–168.
  • Kindt S, Van Oudenhove L, Broekaert D, et al. Immune dysfunction in patients with functional gastrointestinal disorders. Neurogastroenterol Motil. 2009;21(4):389–398.
  • Li M, Zhang L, Lu B, et al. Role of dendritic cell-mediated abnormal immune response in visceral hypersensitivity. Int J Clin Exp Med. 2015;8(8):13243–13250.
  • Miyagawa Y, Murakami A, Ebihara N. The proteolytic effect of mast cell tryptase to eotaxin-1/CCL11·eotaxin-2/CCL24 and eotaxin-3/CCL26 produced by conjunctival fibroblasts. Jpn J Ophthalmol. 2019;63(2):215–220.
  • Sallusto F, Mackay CR. Chemoattractants and their receptors in homeostasis and inflammation. Curr Opin Immunol. 2004;16(6):724–731.
  • Xu XJ, Zhang YL, Liu L, et al. Increased expression of nerve growth factor correlates with visceral hypersensitivity and impaired gut barrier function in diarrhoea-predominant irritable bowel syndrome: a preliminary explorative study. Aliment Pharmacol Ther. 2017;45(1):100–114.
  • Playford RS, Gosh S. What is the role of growth factors in IBD? Inflamm Bowel Dis. 2008;14(2):S119–S120.
  • Rumessen JJ, Gudmand-Hoyer E. Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides. Gut. 1986;27(10):1161–1168.
  • Aarstad HJ, Kolset SO, Seuelid R. The effect of stress in vivo on the function of mouse macrophages in vitro. Scand J Immunol. 1991;33(6):673–681.
  • Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut. Pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol. 2011;62(6):591–599.
  • Enck P, Aziz Q, Barbara G, et al. Irritable bowel disease. Nat Rev Dis Primers. 2016;2(1):16014.
  • Ng QX, Soh AYS, Loke W, et al. The role of inflammation in irritable bowel syndrome (IBS). J Inflamm Res. 2018;11:345–349.
  • Sinagra E, Pompei Tomasello G, Cappello F, et al. Inflammation in irritable bowel syndrome. Myth or new treatment target. World J Gastroenterol. 2016;22(7):2242–2255.
  • Canakis A, Haroon M, Weber HC. Irritable bowel syndrome and gut microbiota. Curr Opin Endocrinol Diabetes Obes. 2020;27(1):28–35.
  • El-Salhy M, Ystad SO, Mazzawi T, et al. Dietary fiber in irritable bowel syndrome. Int J Mol Med. 2017;40(3):607–613.