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Original Article

Activity of Erythromycin and Clindamycin in an Experimental Staphylococcus aureus Infection in Normal and Granulocytopenic Mice

A comparative in vivo and in vitro study

, &
Pages 123-132 | Published online: 07 Feb 2010

References

  • Kunst M W, Mattie H. Cefazolin and cephradine: relationship between antibacterial activity in vitro and in mice experimentally infected with Escherichia coli. J Infect Dis 1978; 137: 391–402
  • Kunst M W, Mattie H. Cefazolin and cephradine: Relationship between serum concentration and tissue contents in mice. Infection 1978; 6: 166–170
  • Mattie H, Van der Voet G B. The relative potency of amoxcillin and ampicillin in vitro and in vivo. Scand J Infect Dis 1981; 13: 291–296
  • Mattie H, Van Dokkum A M, Brus-Weijer L, Krul A M, Van Strijen E. Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics. J Infect Dis 1990; 162: 717–722
  • Dette G A. Serum and tissue concentrations of erythromycin: a review. Curr Med Res Opin 6, Suppl. 1980; 8: 23–28
  • Leigh D A. Antibacterial activity and pharmacokinetics of clindamycin. J Antimicrob Chemother 1981; 7(Suppl A)3–9
  • Garrett E R. Drug action and assay by microbial kinetics. Prog Drug Res 1971; 15: 271–352
  • Stille W, Shah P. Kinetik der Bakterizidie von Ampicillin, Penicillin G, Carbenicillin, Cephalothin, Kanamycin, Gentamicin, Polymyxin B und Sulfamethoxazol/Trimethoprim gegenüber E. coli. Arzneimittelforschung 1973; 23: 58–60
  • Garrett E R. Kinetics of antimicrobial action. Scand J Infect Dis, Suppl 1978; 14: 54–85
  • Sheiner L B, Stanski D R, Vozeh S, Miller R D, Ham J. Simultaneous modelling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine. Clin Pharmacol Ther 1979; 24: 358–371
  • Holford N H G, Sheiner L B. Understanding the dose-effect relationship: Clinical application of a pharmacokinetic pharmacodynamic model. Clin Pharmacokinet 1981; 6: 429–453
  • Mattie H, Goslings W R O, Noach E L. Cloxacillin and nafcillin: Serum binding and its relationship to antibacterial effects in mice. J Infect Dis 1973; 128: 170–177
  • Armitage P. Statistical methods in medical research. Blackwell, Oxford 1971; 444
  • Mattie H. Kinetics of antimicrobial action. Rev Infect Dis 1981; 3: 19–27
  • Fitzgerald S P, Rogers M J. Bacteriostatic effect of serum: role on antibody to lipopolysaccharide. Infect Immun 1980; 27: 302–308
  • Mattie H, Hoogeterp J J, Hermans J. The relation between plasma and tissue concentrations of antibiotics. Description of a method. J Pharmacokinet Biopharm 1987; 15: 191–202
  • Benet L Z, Sheiner L B. Design and optimization of dosage regimens; pharmacokinetic data. Goodman and Gilman's The pharmacological basis of therapeutics, A G Gilman, L S Goodman, A Gilman. Macmillan Publishing Co., New York 1980; 1675–1684

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