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Original

Evaluation of Heterogeneity in Pharmacotherapy Trials for Drug Dependence: A Bayesian Approach

, Ph.D., , M.D., , Ph.D., , Ph.D., , Ph.D., , M.D., , Ph.D. & , Ed.D. show all
Pages 95-102 | Published online: 07 Jul 2009

REFERENCES

  • de Lima M S, de Oliveira Soares B G, Pereira Reisser A A, Farell M. Pharmacological treatment of cocaine dependence: A systematic review. Addiction 2002; 97: 931–949
  • de Lima M S, de Oliveira Soares B G, Pereira Reisser A A, Farell M. Pharmacological treatment of cocaine dependence: a systematic review. Addiction 2002; 97: 931–949
  • Elkashev A, Vocci F. Biological markers of cocaine addiction: Implications for medications development. Addict Biol 2003; 8: 123–139
  • Carroll K M, Nich C, Rounsaville B J. Variability in treatment-seeking cocaine abusers: Implications for clinical pharmacotherapy trials. NIDA Res Monogr 1997; 175: 137–157
  • Nunes E V. Methodologic recommendations for cocaine abuse clinical trials: A clinician-researcher's perspective. NIDA Res Monogr 1997; 175: 73–95
  • Elkashef A, Holmes T H, Bloch D A, Shoptaw S, Kampman K, Reid M S, Somoza E, Ciraulo D, Rotrosen J, Leiderman D, Montgomery A, Vocci F. Retrospective analyses of pooled data from CREST I and CREST II trials for treatment of cocaine dependence. Addiction 2005; 100(Supplement. 1)91–101
  • Hernandez A V, Boersma E, Murray G D, Habbema J DF, Steyerberg E W. Subgroup analyses in therapeutic cardiovascular clinical trials: Are most of them misleading?. Am Heart J 2006; 151: 257–264
  • Counsell C E, Clarke M J, Slattery J, Sandercock P AG. The miracle of DICE therapy for acute stroke: Fact or fictional product of subgroup analysis?. British Med J 1994; 309: 1677–1681
  • ISIS-2 Collaborative Group. Randomized trial of IV streptokinase, oral aspirin, both, or neither among 17187 cases of suspected myocardial infarction. Lancet 1988; 2: 349–360
  • Feinstein A R. The problem of cogent subgroups: A clinicostatistical tragedy. J Clin Epidemiol 1998; 51(4)297–299
  • Brookes S T, Whitely E, Egger M, Smith G D, Mulheran P A, Peters T J. Subgroup analyses in randomized controlled trials: Quantifying the risks of false-positives and false negatives. Executive Summary. Health Technol Assess 2001; 5(33)1–4
  • Assmann S F, Pocock S J, Enos L E, Kasten L E. Subgroup analysis and other (mis)uses of baseline data in clinical trials. Lancet 2000; 355: 1064–1069
  • Pocock S J, Assmann S E, Enos L E, Kasten L E. Subgroup analysis, covariate adjustment and baseline comparisons in clinical trial reporting: Current practice and problems. Stat Med 2002; 21: 2917–2930
  • Rothwell P M. Treating Individuals 2: Subgroup analysis in randomized controlled trials: Importance, indications, and interpretations. Lancet 2005; 365: 176–186
  • Brookes S T, Whitely E, Egger M, Smith G D, Mulheran P A, Peters T J. Subgroup Analyses in randomized trials: Risks of subgroup-specific analyses; power and sample size for interaction tests. J Clin Epidemiol 2004; 57: 229–236
  • Adams K F. Post hoc subgroup analysis and the truth of a clinical trial. Am Heart J 1998; 136(5)753–758
  • Cook D I, Gebski V J, Keech A C. Subgroup analysis in clinical trials. Med J Aust 2004; 180: 289–291
  • Guillemin F. Primer: The fallacy of subgroup analysis. Nat Clin Pract Rheumatology 2007; 3(7)407–413
  • Dixon D O, Simon R. Bayesian Subset Análysis. Biometrics 1991; 47: 871–881
  • Simon R, Freedman L S. Bayesian design and analysis of two X two factorial clinical trials. Biometrics 1997; 53: 456–464
  • Simon R, Dixon D O, Freidlin B. Bayesian subset analysis of a clinical trial for the treatment of HIV infections. Bayesian Biostatistics (Statistics: a Series of Textbooks and Monographs), Donald Berry, Dalene Stangl. Marcel Dekker, New York 1996
  • Simon R. Bayesian subset analysis: Application to studying treatment-by-gender interactions. Stat Med 2002; 21: 2909–2916
  • Goodman S N. Toward Evidence-Based Medical Statistics. 1: The P Value Fallacy. Ann Intern Med 1999; 130: 995–1004
  • Johnstone D J. Tests of significance in theory and practice. Statistician. 1986; 35: 491–504
  • Lucke J F. ‘Fall prevention programs for the elderly: A Bayesian secondary meta-analysis.’. Canadian J Nurs Res 2004; 36(3)48–64
  • Howson C, Urbach P. Scientific reasoning: The Bayesian approach. Open Court, Chicago 2006
  • Firebaugh G. Will Bayesian Inference Help? A Skeptical View. Sociological Methodol 1995; 25: 469–472
  • Spiegelhalter D J, Abrams K R, Myles J P. Bayesian approaches to clinical trials and health-care evaluation. John Wiley & Sons Ltd, West SussexEngland 2004
  • Kadane J B. ‘Prime time for Bayes.’. Control Clin Trials 1995; 16: 313–318
  • Hacking I. An introduction to probability and inductive logic. Cambridge University Press, Cambridge 2001
  • Shimony A. ‘Scientific inference’. Search for a naturalistic world view: Scientific method and epistemology. Cambridge University Press, Cambridge, UK 1993
  • Moeller F G, Schmitz J M, Steinberg J L, Green C M, Reist C, Lai L Y, Swann A C, Grabowski J. Citalopram combined with behavioral therapy reduces cocaine use: A double-blind placebo controlled trial. Am J Drug Alcohol Abuse 2007; 33(3)367–378
  • Bechara A, Damasio H. Decision-making and addiction (part I): Impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. Neuropsychologia 2002; 40: 1675–1689
  • Stout J C, Busemeyer J R, Lin A, Grant S J, Bonson K R. Cognitive modeling analysis of decision-making processes in cocaine abusers. Psychon Bull Rev 2004; 11(4)742–747
  • Moeller F G, Barratt E S, Dougherty D M, Schmitz J M, Swann A C. Psychiatric aspects of impulsivity. Am J Psychiatry 2001; 158: 1783–1793
  • Coffey S F, Gudleski G D, Saladin M E, Brady K T. Impulsivity and rapid discounting of delayed hypothetical rewards in cocaine-dependent individuals. Exp Clin Psychopharmacol 2003; 11: 18–25
  • Patkar A A, Murray H W, Mannelli P, Gottheil E, Weinstein S P, Vergare M J. Pre-treatment measures of impulsivity, aggression and sensation seeking are associated with treatment outcome for African-American cocaine dependent patients. J Addict D/s 2004; 23: 109–122
  • Peroutka S J. Serotonin receptor variants in disease: New therapeutic opportunities?. Ann NY Acad Sci 1998; 861: 16–25
  • Gothert M, Propping P, Bonisch H, Bruss M, Nothen M M. Genetic variation in human 5-HT receptors: potential pathogenetic and pharmacological role. Ann NY Acad Sci 1998; 861: 26–30
  • Cravchik A, Goldman D. Neurochemical individuality: Genetic diversity among human dopamine and serotonin receptors and transporters. Arch Gen Psychiatry 2000; 57: 1105–1114
  • Bjork J M, Moeller F G, Dougherty D M, Swann A C, Machado M A, Hanis C L. Serotonin 2a receptor T102C polymorphism and impaired impulse control. Am J Med Genet 2002; 14: 336–339
  • Glatt C E, Tampilic M, Christie C, DeYoung J, Freimer N B. Re-screening serotonin receptors for genetic variants identifies population and molecular genetic complexity. Am J Med Genet B Neuropsychiatr Genet 2004; 124: 92–100
  • Patkar A A, Mannelli P, Peindl K, Hill K P, Gopalakrishnan R, Berrettini W H. Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients. Psychopharmacology (Be/t) 2006; 1–10
  • Mannelli P, Patkar A A, Peindl K, Tharwani H, Gopalakrishnan R, Hill K P, Berrettini W H. Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls. Psychiatry Res 2006; 144: 99–108
  • Kreek M J, Bart G, Lilly C, LaForge K S, Nielsen D A. Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol Rev 2005; 57: 1–26
  • Kampman K M, Pettinati H, Lynch K G, Dackis C, Sparkman T, Weigley C, O'Brien C P. A pilot trial of topirimate for the treatment of cocaine dependence. Drug Alcohol Depend 2004; 75: 233–240
  • Bechara A, Damasio H, Tranel D, Damasio A R. Deciding advantageously before knowing the advantageous strategy. Science 1997; 275: 1293–1295
  • SAS Institute Inc. Preliminary Capabilities for Bayesian Analysis in SAS/STAT® Software. SAS Institute Inc, Cary, NC 2006
  • Ramsey F P. Truth and Probability. The Foundations of Mathematics and other Logical Essays, F. P. Ramsey, R. B. Braithwaite. Kegan, Paul, Trench, Trubner & Co., London 1926; 156–198, New York: Harcourt, Brace and Company, Ch. VII

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