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Original Article

Effect of Foeniculum vulgare (fennel) on symptoms of depression and anxiety in postmenopausal women: a double-blind randomised controlled trial

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Pages 121-126 | Received 08 Dec 2016, Accepted 13 May 2017, Published online: 11 Sep 2017

References

  • Atkinson C, Compston JE, Day NE, Dowsett M, Bingham SA. 2004. The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial 1-3. The American Journal of Clinical Nutrition 79:326–333.
  • Avis NE, Crawford S, Stellato R, Longcope C. 2001. Longitudinal study of hormone levels and depression among women transitioning through menopause. Climacteric: The Journal of the International Menopause Society 4:243–249.
  • Balk JL, Whiteside DA, Naus G, DeFerrari E, Roberts JM. 2002. A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. Journal of the Society for Gynecologic Investigation 9:238–242.
  • Bosworth HB, Bastian LA, Kuchibhatla MN, Steffens DC, McBride CM, Skinner CS, et al. 2001. Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. Psychosomatic Medicine 63:603–608.
  • Burger HG, MacLennan AH, Huang KE, Castelo-Branco C. 2012. Evidence-based assessment of the impact of the WHI on women’s health. Climacteric: The Journal of the International Menopause Society 15:281–287.
  • Carmignani LO, Pedro AO, Costa-Paiva LH, Pinto-Neto AM. 2010. The effect of dietary soy supplementation compared to estrogen and placebo on menopausal symptoms: a randomized controlled trial. Maturitas 67:262–269.
  • Castellanos J, Gloria AM, Kim SC, Park YS. 2014. The expression of depressive symptomatology in korean american undergraduates: sex and generational differences. Journal of College Counseling 17:208–221.
  • Chagas MH, Tumas V, Loureiro SR, Hallak JE, Trzesniak C, de Sousa JP, et al. 2010. Validity of a Brazilian version of the Zung self-rating depression scale for screening of depression in patients with Parkinson’s disease. Parkinsonism Related Disorders 16:42–45.
  • Clifton-Bligh PB, Nery ML, Clifton-Bligh RJ, Visvalingam S, Fulcher GR, Byth K, et al. 2015. Red clover isoflavones enriched with formononetin lower serum LDL cholesterol-a randomized, double-blind, placebo-controlled study. European Journal of Clinical Nutrition 69:134–142.
  • Garga C, Khan S, Ansari S, Suman A, Garga M. 2009. Chemical composition, therapeutic potential and perspectives of Foeniculum vulgare. Pharmacognosy Reviews 3:346.
  • Ghazanfarpour M, Sadeghi R, Latifnejad Roudsari R, Khadivzadeh T, Khorsand I, Afiat M, et al. 2016. Effects of flaxseed and Hypericum perforatum on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women: a systematic review and meta-analysis. Avicenna Journal of Phytomedicine 6:273–283.
  • Ghazanfarpour M, Sadeghi R, Roudsari RL, Khorsand I, Khadivzadeh T, Muoio B. 2016. Red clover for treatment of hot flashes and menopausal symptoms: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology: The Journal of the Institute of Obstetrics and Gynaecology 36:301–311.
  • Ghazanfarpour M, Kaviani M, Abdolahian S, Bonakchi H, Najmabadi Khadijeh M, Khadivzadeh T, et al. 2015. The relationship between women’s attitude towards menopause and menopausal symptoms among postmenopausal women. Gynecological Endocrinology 31:860–865.
  • Hanach P, Golkhos. 2008. Assessment of soy phytoestrogens and exercise on lipid profiles and menopause symptoms in menopausal women. Journal of Biological Sciences 8:789–793.
  • Hidalgo LA1, Chedraui PA, Morocho N, Ross S, San Miguel G. 2005. The effect of red clover isoflavones on menopausal symptoms, lipids and vaginal cytology in menopausal women: a randomized, double-blind, placebo-controlled study. Gynecological Endocrinology 21:257–264.
  • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. 2005. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 62:593–602.
  • Kishore RN, Anjaneyulu N, Ganesh MN, Sravya N. 2012. Evaluation of anxiolytic activity of ethanolic extract of Foeniculum vulgare in mice model. Internationbal Journal of Pharmacy and Pharmaceutical Sciences 4:584–586.
  • Kok L, Kreijkamp-Kaspers S, Grobbee DE, Lampe JW, van der Schouw YT. 2005. A randomized, placebo-controlled trial on the effects of soy protein containing isoflavones on quality of life in postmenopausal women. Menopause (New York, NY) 12:56–62.
  • Koppula S, Kumar H. 2013. Foeniculum vulgare Mill (Umbelliferae) attenuates stress and improves memory in wister rats. Tropical Journal of Pharmaceutical Research 12:553–558.
  • Kotsopoulos D, Dalais F, Liang Y-L, McGrath B, Teede H. 2000. The effects of soy protein containing phytoestrogens on menopausal symptoms in postmenopausal women. Climacteric: The Journal of the International Menopause Society 3:161–167.
  • Lipovac M, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M. 2010. Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts. Maturitas 65:258–261.
  • Lisspers J, Nygren A, Söderman E. 1997. Hospital Anxiety and Depression Scale (HAD): some psychometric data for a Swedish sample. Acta Psychiatrica Scandinavica 96:281–286.
  • Luca M, Luca A, Musumeci ML, Fiorentini F, Micali G, Calandra C. 2016. Psychopathological Variables and Sleep Quality in Psoriatic Patients. International Journal of Molecular Sciences 17:1184.
  • Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. 2014. Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women. Health Care for Women International 35:87–99.
  • Mesfin M, Asres K, Shibeshi W. 2014. Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice. BMC Complementary and Alternative Medicine 14:310.
  • Michopoulos I, Douzenis A, Kalkavoura C, Christodoulou C, Michalopoulou P, Kalemi G, et al. 2008. Hospital Anxiety and Depression Scale (HADS): validation in a Greek general hospital sample. Annals of General Psychiatry 7:4.
  • Montazeri A, Vahdaninia M, Ebrahimi M, Jarvandi S. 2003. The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version. Health and Quality of Life Outcomes 1:14.
  • Pahlavanzadeh Navidian A, Yazdani M. 2010. The effect of psycho-education on depression, anxiety and stress in family caregivers of patients with mental disorders. Journal of Kermanshah University of Medical Sciences 14:228–236.
  • Prestwood KM, Kenny AM, Kleppinger A, Kulldorff M. 2003. Ultralow-dose micronized 17beta-estradiol and bone density and bone metabolism in older women: a randomized controlled trial. JAMA 290:1042–1048.
  • Reed SD, Ludman EJ, Newton KM, Grothaus LC, LaCroix AZ, Nekhlyudov L, et al. 2009. Depressive symptoms and menopausal burden in the midlife. Maturitas 62:306–310.
  • Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kopperberg C, Stefanick ML, Writing Group of Women´s Health Initiative Investigators, et al. 2002. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 288:321–333.
  • Sadrefozalayi S, Farokhi F. 2014. Effect of the aqueous extract of Foeniculum vulgare (fennel) on the kidney in experimental PCOS female rats. Avicenna Journal of Phytomedicine 4:110–117.
  • Singh JN, Sunil K, Rana A. 2013. Antidepressant activity of methanolic extract of Foeniculum vulgare (fennel) fruits in experimental animal models. Journal of Applied Pharmaceutical Science 3:65.
  • Tice JA, Ettinger B, Ensrud K, Wallace R, Blackwell T, Cummings SR. 2003. Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial. JAMA 290:207–214.
  • Wei P, Liu M, Chen Y, Chen DC. 2012. Systematic review of soy isoflavone supplements on osteoporosis in women. Asian Pacific Journal of Tropical Medicine 5:243–248.
  • Weissman MM1, Klerman GL. 1992. Depression: current understanding and changing trends. Annual Review of Public Health 13:319–339.
  • Zigmond AS, Snaith RP. 1983. The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica 67:361–370.
  • Zweifel JE, O’Brien WH. 1997. A meta-analysis of the effect of hormone replacement therapy upon depressed mood. Psychoneuroendocrinology 22:189–212.

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