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Original Articles

Lycopene and Chemotherapy Toxicity

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Pages 988-995 | Received 26 Apr 2010, Accepted 16 Jul 2010, Published online: 04 Oct 2010

REFERENCES

  • Conklin , K A . 2000 . Dietary antioxidants during cancer chemotherapy: impact on chemotherapeutic effectiveness and development of side effects . Nutr Cancer , 37 : 1 – 18 .
  • Lawenda , B D , Kelly , K M , Ladas , E J , Sagar , S M Vickers , A . 2008 . Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? . J Natl Cancer Inst , 100 : 773 – 783 .
  • Yilmaz , S , Sahna , E , Karahan , I and Ozer , S . 2006 . Protective effect of lycopene on Adriamycin-induced cardiotoxicity and nephrotoxicity . Toxicology , 218 : 164 – 171 .
  • Dogukan , A , Tuzcu , M , Agca , C A , Gencoglu , H Sahin , N . 2010 . A Tomato lycopene complex protects the kidney from cisplatin-induced injury by affecting oxidative stress, Bax, Bcl-2 and HSPs expression. . Nutr Cancer , Forthcoming
  • Do Amaral , C L , Francescato , H D , Coimbra , T M , Costa , R S Darin , J D . 2008 . Resveratrol attenuates cisplatin-induced nephrotoxicity in rats . Arch Toxicol , 82 : 363 – 370 .
  • Tatlidede , E , Sehirli , O , Velioglu-Ogunc , A , Cetinel , S Yegen , B C . 2009 . Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage . Free Radic Res , 43 : 195 – 205 .
  • Berthiaume , J M , Oliveira , P J , Fariss , M W and Wallace , K B . 2005 . Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction . Cardiovasc Toxicol , 5 : 257 – 267 .
  • Deres , P , Halmosi , R , Toth , A , Kovacs , K Palfi , A . 2005 . Prevention of doxorubicin-induced acute cardiotoxicity by an experimental antioxidant compound . J Cardiovasc Pharmacol , 45 : 36 – 43 .
  • Maliakel , D M , Kagiya , T V and Nair , C K . 2008 . Prevention of cisplatin-induced nephrotoxicity by glucosides of ascorbic acid and alpha-tocopherol . Exp Toxicol Pathol , 60 : 521 – 527 .
  • Shimeda , Y , Hirotani , Y , Akimoto , Y , Shindou , K Ijiri , Y . 2005 . Protective effects of capsaicin against cisplatin-induced nephrotoxicity in rats . Biol Pharm Bull , 28 : 1635 – 1638 .
  • Kuhad , A , Pilkhwal , S , Sharma , S , Tirkey , N and Chopra , K . 2007 . Effect of curcumin on inflammation and oxidative stress in cisplatin-induced experimental nephrotoxicity . J Agric Food Chem , 55 : 10150 – 10155 .
  • Mohamad , R H , El-Bastawesy , A M , Zekry , Z K , Al-Mehdar , H A Al-Said , M G . 2009 . The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats . J Med Food , 12 : 394 – 402 .
  • Razo-Rodríguez , A C , Chirino , Y I , Sánchez-González , D J , Martínez-Martínez , C M Cruz , C . 2008 . Garlic powder ameliorates cisplatin-induced nephrotoxicity and oxidative stress . J Med Food , 11 : 582 – 586 .
  • Psotová , J , Chlopcíková , S , Miketová , P , Hrbác , J and Simánek , V . 2004 . Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes: Part III. Apigenin, baicalelin, kaempherol, luteolin and quercetin . Phytother Res , 18 : 516 – 521 .
  • Sies , H . 1997 . Oxidative stress: oxidants and antioxidants . Exp Physiol , 82 : 291 – 295 .
  • Beckman , K B and Ames , B N . 1998 . The free radical theory of aging matures . Physiol Rev , 78 : 547 – 581 .
  • Block , K I , Koch , A C , Mead , M N , Tothy , P K Newman , R A . 2007 . Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials . Cancer Treat Rev , 33 : 407 – 418 .
  • Block , K I , Koch , A C , Mead , M N , Tothy , P K Newman , R A . 2008 . Gyllenhaal C.Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials . Int J Cancer , 123 : 1227 – 1239 .
  • Chen , Y , Jungsuwadee , P , Vore , M , Butterfield , D A and St Clair , D K . 2007 . Collateral damage in cancer chemotherapy: oxidative stress in nontargeted tissues . Mol Interv , 7 : 147 – 156 .
  • Hug , H , Strand , S , Grambihler , A , Galle , J Hack , V . 1997 . Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells . J Bio Chem , 272 : 28191 – 28193 .
  • Singal , P K , Iliskovic , N , Li , T and Kumar , D . 1997 . Adriamycin cardiomyopathy: Pathophysiology and prevention . FASEB J , 11 : 931 – 936 .
  • Tangpong , J , Cole , M P , Sultana , R , Estus , S Vore , M . 2007 . Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: Insight into the mechanism of chemobrain . J Neurochem , 100 : 191 – 201 .
  • Alberts , D S and Noel , J K . 1995 . Cisplatin-associated neurotoxicity: can it be prevented? . Anticancer Drug , 6 : 369 – 383 .
  • Taguchi , T , Nazneen , A , Abid , M R and Razzaque , M S . 2005 . Cisplatin-associated nephrotoxicity and pathological events . Contrib Nephrol , 148 : 107 – 121 .
  • Hrelia , S , Bordoni , A , Angeloni , C , Leoncini , E and Biagi , P . 2004 . Nutritional interventions to counteract oxidative stress in cardiac cells . Ital J Biochem , 53 : 157 – 163 .
  • Clemens , M R , Waladkhani , A R , Bublitz , K , Ehninger , G and Gey , K F . 1997 . Supplementation with antioxidants prior to bone marrow transplantation . Wien Klin Wochenschr , 109 : 771 – 776 .
  • Agarwal , S and Rao , A V . 2000 . Tomato lycopene and its role in human health and chronic diseases . CMAJ , 163 : 739 – 744 .
  • Nguyen , M L and Schwartz , S J . 1999 . Lycopene: chemical and biological properties . Food Technol , 53 : 38 – 45 .
  • DiMascio , P , Kaiser , S and Sies , H . 1989 . Lycopene as the most effective biological carotenoid singlet oxygen quencher . Arch Biochem Biophys , 274 : 532 – 538 .
  • Heber , D and Lu , Q-Y . 2002 . Overview of mechanisms of action of lycopene . Exp Biol Med , 227 : 920 – 923 .
  • Amin , A R , Kucuk , O , Khuri , F R and Shin , D M . 2009 . Perspectives for cancer prevention with natural compounds . J Clin Oncol , 27 : 2712 – 2725 .
  • Kucuk , O , Sarkar , F H , Sakr , W , Djuric , Z Pollak , M N . 2001 . Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy . Cancer Epidemiol Biomarkers Prev , 10 : 861 – 868 .
  • Seren , S , Lieberman , R , Bayraktar , U D , Heath , E Sahin , K . 2008 . Lycopene in cancer prevention and treatment . Am J Ther , 15 : 66 – 81 .
  • Bertram , J S . 1999 . Carotenoids and gene regulation . Nutrition Rev , 57 : 182 – 191 .
  • Karas , M , Amir , H , Fishman , D , Danilenko , M Segal , S . 2000 . Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells . Nutr Cancer , 36 : 101 – 111 .
  • Giovannucci , E . 2002 . A review of epidemiologic studies of tomatoes, lycopene, and prostate cancer . Exp Biol Med , 227 : 852 – 859 .
  • Bertram , J S and Bortkiewicz , H . 1995 . Dietary carotenoids inhibit neoplastic transformation and modulate gene expression in mouse and human cells . Am J Clin Nutr , 62 : 1327 – 1336 .
  • Zhang , L-X , Cooney , R V and Bertram , J S . 1991 . Carotenoids enhance gap junctional communication and inhibit lipid peroxidation inC3H/10T1/2 cells: relationship to their cancer chemopreventive action . Carcinogenesis , 12 : 2109 – 2114 .
  • Gius , D , Botero , A , Shah , S and Curry , H A . 1999 . Intracellular oxidation/ reduction status in the regulation of transcription factors NFkappaB and AP-1 . Toxicol Lett , 106 : 93 – 106 .
  • Rao , A V , Fleshner , N and Agarwal , S . 1999 . Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case-control study . Nutr Cancer , 33 : 159 – 164 .
  • Siler , U , Barella , L , Spitzer , V , Scnorr , J Lein , M . 2004 . Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model . FASEB J , 18 : 1019 – 1021 .
  • Hazai , E , Bikadi , Z , Zsila , S and Lockwood , S F . 2006 . Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyl, and selected oxidative metabolites with 5-lipoxygenase . Bioorg Med Chem , 14 : 6859 – 6867 .
  • Jewell , C and O’Brien , N M . 1999 . Effect of dietary supplementation with carotenoids on xenobiotic metabolizing enzymes in the liver, lung, kidney and small intestine of the rat . Br J Nutr , 81 : 235 – 242 .
  • Chew , B P and Park , J S . 2004 . Carotenoid action on the immune response . J Nutr , 134 : 257 – 261 .
  • Faber , M , Coudray , C , Hida , H , Mousseau , M and Favier , A . 1995 . Lipid peroxidation products and vitamin and trace element status in patients with cancer before and after chemotherapy including adriamycin. a preliminary study . Biol Trace Elem Res , 47 : 117 – 123 .
  • Sangeetha , P , Das , U N , Koratkar , R and Suryaprabha , P . 1990 . Increase in free radical generation and lipid peroxidation following chemotherapy in patients with cancer . Free Radic Biol Med , 8 : 15 – 19 .
  • Weijl , N I , Hopman , G D , Wipkink-Bakker , A , Lentjes , EGWM Berger , H M . 1998 . Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients . Ann Oncol , 9 : 1331 – 1337 .
  • Erhola , M , Kellokumpu-Lehtinen , P , Metsa-Ketela , T , Alanko , K and Nieminen , M M . 1996 . Effects of anthracyclin-based chemotherapy on total plasma antioxidant capacity in small cell lung cancer patients . Free Radic Biol Med , 21 : 383 – 390 .
  • D’Incalci , M , Steward , W P and Gescher , A J . 2007 . Modulation of response to cancer chemotherapeutic agents by diet constituents: is the available evidence sufficiently robust for rational advice for patients? . Cancer Treat Rev , 33 : 223 – 229 .
  • Salganik , R I . 2001 . The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population . J Am Coll Nutr , 20 ( 73–75 ) : 464 – 472 .
  • Prasad , K N , Kumar , A , Kochupillai , V and Cole , W C . 1999 . High doses of multiple antioxidant vitamins: essential ingredients in improving the efficacy of standard cancer therapy . J Am Coll Nutr , 18 : 13 – 25 .
  • Karimi , G , Ramezani , M and Abdi , A . 2005 . Protective effects of lycopene and tomato extract against doxorubicin-induced cardiotoxicity . Phytother Res , 19 : 912 – 914 .
  • Sendão , M C , Behling , E B , dos Santos , R A , Antunes , L M and de Lourdes Pires Bianchi , M . 2006 . Comparative effects of acute and subacute lycopene administration on chromosomal aberrations induced by cisplatin in male rats . Food Chem Toxicol , 44 : 1334 – 1339 .
  • Zhou , C , Han , W , Zhang , P , Cai , M Wei , D . 2008 . Lycopene from tomatoes partially alleviates the bleomycin-induced experimental pulmonary fibrosis in rats . Nutr Res , 28 : 122 – 130 .
  • Ferreira , A L , Salvadori , D M , Nascimento , M C , Rocha , N S Correa , C R . 2007 . Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats . Mutat Res , 631 : 26 – 35 .
  • Rios , A O , Antunes , L MG and Bianchi , M LP . 2009 . Bixin and lycopene modulation of free radical generation induced by cisplatin–DNA interaction . Food Chemistry , 113 : 1113 – 1118 .
  • Van Breemen , R B and Pajkovic , N . 2008 . Multitargeted therapy of cancer by lycopene . Cancer Lett , 269 : 339 – 351 .
  • Krinsky , N I . 1992 . Mechanism of action of biological antioxidants . Proc Soc Exp Biol Med , 200 : 248 – 254 .
  • Bast , A , Haenen , G R , Van Den Berg , R and Van Den Berg , H . 1998 . Antioxidant effects of carotenoids . Int J Vitam Nutr Res , 68 : 399 – 403 .
  • Park , Y O , Hwang , E S and Moon , T W . 2005 . The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells . Biofactors , 23 : 129 – 139 .
  • Avc , A , Cetin , R , Erguder , I B , Devrim , E Kilicoglu , B . 2008 . Cisplatin causes oxidation in rat liver tissues: possible protective effects of antioxidant food supplementation . Turk J Med Sci , 38 : 117 – 120 .
  • Puri , T , Julka , P K , Goyal , S , Nair , O Sharma , D N . 2005 . Role of natural lycopene and phytonutrients along with radiotherapy and chemotherapy in high-grade gliomas . J Clin Oncol 2005 ASCO Annual Meeting Proc , 23 (16 Suppl) : 1561

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