250
Views
104
CrossRef citations to date
0
Altmetric
SHORT COMMUNICATION

VARIATION IN THE VITAMIN D RECEPTOR GENE IS ASSOCIATED WITH MULTIPLE SCLEROSIS IN AN AUSTRALIAN POPULATION

, , , , , , & show all
Pages 25-38 | Received 03 Nov 2004, Accepted 16 Apr 2005, Published online: 11 Jul 2009

REFERENCES

  • Arndt, V., Strassburg, C.P., & Manns, M.P. (2002). Genetic Association of Vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis. Hepatology 35, 126–131.
  • Bell, N.H., Morrison, N.A., Nguyen, T.V., Eisman, J., & Hollis, B.W. (2001). ApaI polymorphisms of the vitamin D receptor predict bone density of the lumbar spine and not racial difference in bone density in young men. J. Lab. Clin. Med. 137, 133–140. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Bhalla, A.K., Ameneto, E.P., & Krane, S.M. (1986). Dihydroxyvitamin D3 on human lymphocytes and monocytes/macrophages inhibition of IL-2 and augmentation of IL-1 production. Cell. Immunol. 98, 311–322. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Cantorna, M.T., Hayes, C.E., & DeLuca, H.F. (1996). 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc. Nat. Acad. Sci. US 93, 7861–7864. [CSA], [CROSSREF]
  • Cantorna, M.T., Woodward, B., Hayes, C.E., & DeLuca, H.F. (1998). 1,25-dihydroxyvitamin D3 is a positive regulator for the two antiencephalitogenic cytokines TGF-ß1 and IL-4. J Immunol. 160, 5314–5319. [PUBMED], [INFOTRIEVE]
  • Cautain, B., Damoiseaux, J., Bernard, I., vanStraaten, H., van Breda Vriesman, P., Boneu, B., Druet, P., & Saoudi, A. (2001). Essential role of TGF-beta in the natural resistance to experimental allergic encephalomyelitis in rats. Eur. J. Immunol. 31, 1132–1140. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Chabas, D., Baranzini, S.E., Mitchell, D., Bernard, C.C., Rittling, S.R., Denhardt, D.T., Sobel, R.A., Lock, C., Karpuj, M., Pedotti, R., Heller, R., Oksenberg, J.R., & Steinman, L., 2001). The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 294, 1731–1735. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Coraddu, F., Lai, M., Mancosu, C., Cocco, E., Sawcer, S., Setakis, E., Compston, A., & Marrosu, M.G. (2003). A genome-wide screen for linkage disequilibrium in sardinian multiple sclerosis. J. Neuroimmunol. 143, 120–123. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Cosman, F., Nieves, J., Komar, L., Ferrer, G., Herbert, J., Formica, C., Shen, V., & Lindsay, R., 1998). Fracture history and bone loss in patients with MS. Neurology 51, 1161–1165. [PUBMED], [INFOTRIEVE], [CSA]
  • Curran, J.E., Vaughan, T., Lea, R.A., Weinstein, S.R., Morrison, N.A., & Griffiths, L.R (1999). Association of a vitamin D receptor polymorphism with sporadic breast cancer development. Int. J. Cancer 83, 723–726. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Fukazawa, T., Yabe, I., Kikuchi, S., Sasaki, H., Hamada, T., Miyasaka, K., & Tashiro, K.., 1999). Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese. J. Neurol. Sci. 166, 47–52. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Goertsches, R., Villoslada, P., Comabella, M., Montalban, X., Navarro, A., de la Concha, E.G., Arroyo, R., Lopez de Munain, A., Otaegui, D., Palacios, R,. Perez-Tur, J., Jonasdottir, A., Benediktsson, K., Fossdal, R., Sawcer, S., Setakis, E., & Compston, A., 2003). A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease. J. Neuroimmunol. 143, 124–128. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Haschek, W.M., Krook, L., Kallfelz, F.A., & Pond, W.G (1978). Vitamin D toxicity. Initial site and mode of action. Cornell Vet. 68, 324–378.
  • Huang, C.M., Wu, M.C., Wu, J.Y., & Tsai, F.J (2002). Association of vitamin D receptor geneBsmI polymorphisms in Chinese patients with systemic lupus erythematosus. Lupus 11, 31–34. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Kinuta, K., Tanaka, H., Moriwaka, T., Arya, K., Kato, S., & Scino, Y.., 2000). Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. Endocrinology 141, 1317–1324. [PUBMED], [CSA], [CROSSREF]
  • Kurland, L.T (1952). The frequency and geographic distribution of multiple sclerosis as indicated by mortality statistics and morbidity surveys in the United States and Canada. Amer. J. Hygiene 55, 457–476.
  • Manolagas, S.C (1987). Vitamin D and the relevance to cancer. Anticancer Res. 7, 237–245.
  • Mathieu, C., Laureys, J., Sobis, H., Vandeputte, M., Waer, M., & Bouillon, R, (1992), 1,25-Dihydroxyvitamin D3 prevents insulitis in NOD mice. Diabetes 41, 1491–1495. [PUBMED], [INFOTRIEVE]
  • Meehan, T.F. & De Luca, H.F (2002). The vitamin D receptor is necessary for 1alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice. Arch. Biochem. Biophys. 408, 200–204. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Miyamoto, K., Kesterson, R.A., Yamamoto, H., Taketani, Y., Nishiwaki, E., Tatsumi, S., Inoue, Y., Morita, K., Takeda, E., & Pike, J.W (1997). Structural organization of the human vitamin D receptor chromosomal gene and its promoter. Molec. Endocrinol. 11, 1165–1179. [CSA], [CROSSREF]
  • Morrison, N.A., Qi, J.C., Tokita, A., Kelly, P.J., Crofts, L., Nguyen, T.V., Sambrook, P.N., & Eisman, J.A (1994). Prediction of bone density from vitamin D receptor alleles. Nature 367, 284–287. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Muller, K. & Bendtzen, K., 1992). Inhibition of human T lymphocyte proliferation and cytokine production by 1,25-dihydroxyvitamin D3. Different effects on CD45RA+ and CD45RO+ cells. Autoimmunity 14, 37–43.
  • Muller, K. & Bendtzen, K., 1996). 1,25-dihydroxyvitamin D3 as a natural regulator of human immune functions. J. Investig. Dermatol. Symp. Proc. 1, 68–71. [PUBMED], [INFOTRIEVE], [CSA]
  • Nataf, S., Garcion, E., Darcy, F., Chabannes, D., Muller, J.Y., & Brachet, P., 1996). 1,25-dihydroxyvitamin D3 exerts regional effects in the central nervous system during experimental allergic encephalomyelitis. J. Neuro. Exper. Neurol. 55, 904–914. [CSA]
  • Nieves, J., Cosman, F., Herbert, J., Shen, V., & Lindsay, R., 1994). High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis. Neurology 44, 1687–1692. [PUBMED], [INFOTRIEVE], [CSA]
  • Niino, M., Fukazawa, T., Yabe, I., Kikuchi, S., Sasaki, H., & Tashiro K. (2000). Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles. J. Neurol. Sci. 177, 65–71. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Peter, J., Malloy, T., Eccleshall, R., Gross, C., Van Maldergem, L., Bouillon, R., & Feldman D. (1997). Hereditary Vitamin D resistant rickets caused by a novel mutation in the Vitamin D receptor that results in decreased affinity for hormone and cellular hyporesponsiveness. J. Clin. Invest. 99, 297–304. [CSA]
  • Schrijver, H.M., Hooper-Van Veen, T., Van Belzen, M.J., Crusius, J.B., Pena, A.S., Barkhof, F., Polman, C.H., & Uitdehaag, B.M (2004). Polymorphisms in the genes encoding interferon-gamma and interferon-gamma receptors in multiple sclerosis. Eur. J. Immunogenet. 31, 133–140. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Skrabic, V., Zemunik, T., Situm, M., & Terzic, J., 2003). Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in the Dalmatian population. Diabetes. Res. Clin. Pract. 59, 31–35. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Steckley, J.L., Dyment, D.A., Sadovnick, A.D., Risch, N., Hayes, C., & Ebers, G.C (2000). Genetic analysis of vitamin D related genes in Canadian multiple sclerosis. Canadian collaborative study group. Neurology 54, 729–732. [CSA]
  • Tajouri, L., Mellick, A.S., Ashton, K.J., Tannenberg, A.E., Nagra, R.M., Tourtellotte, W.W., & Griffiths, L.R (2003). Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis. Molec. Brain Res. 119, 170–183. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Tsoukas, C.D., Provdini, D.M., & Manolagas, S.C (1984). 1,25-Dihydroxyvitamin D3: a novel immune regulatory hormone. Science 224, 1438–1440. [PUBMED], [INFOTRIEVE]
  • Van Etten, E., Branisteanu, D.D., Overbergh, L., Bouillon, R., Verstuyf, A., & Mathieu, C. (2003). Combination of a 1,25-dihydroxyvitamin D3 analog and a bisphosphonate prevents experimental autoimmune encephalomyelitis and preserves bone. Bone 32, 397–404. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Vidal, M., Ramana, C.V., & Dusso, A.S (2002). Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription. Molec. Cell. Biol. 22, 2777–2287. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Wilkinson, R.J., Llewelyn, M., Toossi, Z., Patel, P., Pasvol, G., Lalvani, A., Wright, D., Latif, M., & Davidson, R.N (2000). Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet 355, 618–621. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Wilson, R.L (1992). Free radical-induced biological damage and the critical roles of vitamin A, vitamin C, vitamin D and vitamin E and of copper, iron, selenium and zinc. J. Nutr. Sci. Vitaminol. 3, 541–544.
  • Zeitz, U., Weber, K., Soegiarto, D.W., Wolf, E., Balling, R., & Erben, R.G (2003). Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor. FASEB J. 17, 509–511. [PUBMED], [INFOTRIEVE]
  • Zhao, J.H (2004). 2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis. Bioinformatics 20, 1325–1326. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.