IN VITRO MODELING OF HUMAN ALVEOLAR MACROPHAGE SMOKE EXPOSURE: ENHANCED INFLAMMATION AND IMPAIRED FUNCTION

REFERENCES

• Lohmann-Matthes M L, Steinmuller C, Franke-Ullmann G. Pulmonary macrophages. Eur Respir J 1994; 7: 1678–1689
   PubMed Web of Science ®Google Scholar
• Geiser M. Morphological aspects of particle uptake by lung phagocytes. Microsc Res Tech 2002; 57: 512–522
   PubMed Web of Science ®Google Scholar
• Barnes P J. Alveolar macrophages as orchestrators of COPD. COPD: J Chron Obstruct Pulmon Dis 2004; 1: 59–70
   Google Scholar
• Russell R E, Thorley A, Culpitt S V, Dodd S, Donnelly L E, Demattos C, Fitzgerald M, Barnes P J. Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases. Am J Physiol Lung Cell Mol Physiol 2002; 283: L867–L873
   PubMed Web of Science ®Google Scholar
• Reynolds H Y. Use of bronchoalveolar lavage in humans-past necessity and future imperative. Lung 2000; 178: 271–293
   PubMed Web of Science ®Google Scholar
• Barnes P J. Alveolar Macrophages as Orchestrators of COPD. COPD: J Chron Obstruct Pulmon Dis 2004; 1: 59–70
   Google Scholar
• Barnes P J. Mediators of chronic obstructive pulmonary disease. Pharmacol Rev 2004; 56: 515–548
   PubMed Web of Science ®Google Scholar
• Ito K, Lim S, Caramori G, Chung K F, Barnes P J, Adcock I M. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB J 2001; 1110–1112
   PubMedGoogle Scholar
• Culpitt S V, Rogers D F, Shah P, De Matos C, Russell R EK, Donnelly L E, Barnes P J. Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003; 167: 24–31
   PubMed Web of Science ®Google Scholar
• Cosio B G, Tsaprouni L, Ito K, Jazrawi E, Adcock I M, Barnes P J. Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J. Exp. Med 2004; 200: 689–695
   Web of Science ®Google Scholar
• Hodge S, Hodge G, Ahern J, Jersmann H, Holmes M, Reynolds P N. Smoking alters alveolar macrophage recognition and phagocytic ability: implications in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2007; 37: 748–755
   PubMed Web of Science ®Google Scholar
• Hodge S, Hodge G, Scicchitano R, Reynolds P N, Holmes M. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol 2003; 81: 289–296
   PubMed Web of Science ®Google Scholar
• Becker S, Warren M, Haskill S. Colony-stimulating factor-nduced monocyte survival and differentiation into macrophages in serum-free cultures. J Immunol 1987; 139: 3703–3709
   PubMed Web of Science ®Google Scholar
• Frendl G. Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. Int J Immunopharmacol 1992; 14: 421–430
   PubMed Web of Science ®Google Scholar
• Young D A, Lowe L D, Clark S C. Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibody-dependent cellular cytotoxicity. J Immunol 1990; 145: 607–615
   PubMed Web of Science ®Google Scholar
• Akagawa K S. Functional heterogeneity of colony-stimulating factor-induced human monocyte-derived macrophages. Int J Hematol 2002; 76: 27–34
   PubMed Web of Science ®Google Scholar
• Metcalf D. The molecular biology and functions of the granulocyte-macrophage colony-timulating factors. Blood 1986; 67: 257–267
   PubMed Web of Science ®Google Scholar
• Geissler K, Harrington M, Srivastava C, Leemhuis T, Tricot G, Broxmeyer H. Effects of recombinant human colony stimulating factors (CSF) (granulocyte-macrophage CSF, granulocyte CSF, and CSF-1) on human monocyte/macrophage differentiation. J Immunol 1989; 143: 140–146
   PubMed Web of Science ®Google Scholar
• Stanley E R, Guilbert L J, Tushinski R J, Bartelmez S H. CSF-1-a mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem 1983; 21: 151–159
   PubMed Web of Science ®Google Scholar
• Tomokiyo R, Jinnouchi K, Honda M, Wada Y, Hanada N, Hiraoka T, Suzuki H, Kodama T, Takahashi K, Takeya M. Production, characterization, and interspecies reactivities of monoclonal antibodies against human class A macrophage scavenger receptors. Atherosclerosis 2002; 161: 123–132
   PubMed Web of Science ®Google Scholar
• Arredouani M S, Palecanda A, Koziel H, Huang Y C, Imrich A, Sulahian T H, Ning Y Y, Yang Z, Pikkarainen T, Sankala M, Vargas S O, Takeya M., Tryggvason K, Kobzik L. MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages. J Immunol 2005; 175: 6058–64
   PubMed Web of Science ®Google Scholar
• Stringer B, Imrich A, Kobzik L. Flow cytometric assay of lung macrophage uptake of environmental particulates. Cytometry 1995; 20: 23–32
   PubMedGoogle Scholar
• Sulahian T H, Imrich A, Deloid G, Winkler A R, Kobzik L. Signaling pathways required for macrophage scavenger receptor-mediated phagocytosis: analysis by scanning cytometry. Respir Res Aug 7, 2008; 9: 59
   PubMed Web of Science ®Google Scholar
• Luppi F, Aarbiou J, van Wetering S, Rahman I, de Boer W I, Rabe K F, Hiemstra P S. Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione. Respir Res 2005; 6: 140
   PubMed Web of Science ®Google Scholar
• Silver R F, Walrath J, Lee H, Jacobson B A, Horton H, Bowman M R, Nocka K, Sypek J P. Human Alveolar Macrophage Gene Responses to Mycobacterium tubercilosis Strains H37Ra and H37Rv. Am J Respir Cell Mol Biol Sep 11, 2008, [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Woodruff P G, Koth L L, Yang Y H, Rodriguez M W, Favoreto S, Dolganov G M, Paquet A C, Erle D J. A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med 2005; 172: 1383–1392
   PubMed Web of Science ®Google Scholar
• Alden T D, Pittman D D, Beres E J, Hankins G R, Kallmes D F, Wisotsky B M, Kerns K M, Helm G A. Percutaneous spinal fusion using bone morphogenetic protein-2 gene therapy. J Neurosurg 1999; 90: 109–114
   PubMed Web of Science ®Google Scholar
• Viksman M Y, Bochner B S, Peebles R S, Schleimer R P, Liu M C. Expression of activation markers on alveolar macrophages in allergic asthmatics after endobronchial or whole–lung allergen challenge. Clin Immunol 2002; 104: 77–85
   PubMed Web of Science ®Google Scholar
• Viksman M Y, Liu M C, Bickel C A, Schleimer R P, Bochner B S. Phenotypic analysis of alveolar macrophages and monocytes in allergic airway inflammation. I. Evidence for activation of alveolar macrophages, but not peripheral blood monocytes, in subjects with allergic rhinitis and asthma. Am J Respir Crit Care Med 1997; 155: 858–863
   PubMed Web of Science ®Google Scholar
• Lofdahl J M, Wahlstrom J, Skold C M. Different inflammatory cell pattern and macrophage phenotype in chronic obstructive pulmonary disease patients, smokers and non-smokers. Clin Exp Immunol 2006; 145: 428–437
   PubMed Web of Science ®Google Scholar
• Haugen T S, Skjonsberg O H, Nakstad B, Lyberg T. Modulation of adhesion molecule profiles on alveolar macrophages and blood leukocytes. Respiration 1999; 66: 528–37
   PubMed Web of Science ®Google Scholar
• Richeldi L, Mariani M, Losi M, Maselli F, Corbetta L, Buonsanti C, Colonna M, Sinigaglia F, Panina-Bordignon P, Fabbri L M. Triggering receptor expressed on myeloid cells: role in the diagnosis of lung infections. Eur Respir J 2004; 24: 247–50
   PubMed Web of Science ®Google Scholar
• Pons A R, Noguera A, Blanquer D, Sauleda J, Pons J, Agusti A G. Phenotypic characterisation of alveolar macrophages and peripheral blood monocytes in COPD. Eur Respir J 2005; 25: 647–652
   PubMed Web of Science ®Google Scholar
• Burke B, Sumner S, Maitland N, Lewis C E. Macrophages in gene therapy: cellular delivery vehicles and in vivo targets. J Leukoc Biol 2002; 72: 417–428
   PubMed Web of Science ®Google Scholar
• Di Nicola M, Carlo-Stella C, Milanesi M, Magni M, Longoni P, Mortarini R, Anichini A, Tomanin R, Scarpa M, Gianni A M. Large-scale feasibility of gene transduction into human CD34+ cell-derived dendritic cells by adenoviral/polycation complex. Br J Haematol 2000; 111: 344–50
   PubMed Web of Science ®Google Scholar
• Shapiro S D. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: 29S–32S
   PubMed Web of Science ®Google Scholar
• Ofulue A F, Ko M. Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema. Am J Physiol Lung Cell Mol Physiol 1999; 277: L97–L105
   PubMed Web of Science ®Google Scholar
• Landsman L, Jung S. Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J Immunol 2007; 179: 3488–3494
   PubMed Web of Science ®Google Scholar
• Nicod L P. Pulmonary defence mechanisms. Respiration 1999; 66: 2–11
   PubMed Web of Science ®Google Scholar
• Tarling J, Lin H, Hsu S. Self-renewal of pulmonary alveolar macrophages: evidence from radiation chimera studies. J Leukoc Biol 1987; 42: 443–446
   PubMed Web of Science ®Google Scholar
• Murphy J, Summer R, Wilson A A, Kotton D N, Fine A. The prolonged life-span of alveolar macrophages. Am J Respir Cell Mol Biol 2008; 38: 380–385
   PubMed Web of Science ®Google Scholar
• Shibata Y, Zsengeller Z, Otake K, Palaniyar N, Trapnell B C. Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema. Blood 2001; 98: 2845–2852
   PubMed Web of Science ®Google Scholar
• Bonfield T L, Raychaudhuri B, Malur A, Abraham S, Trapnell B C, Kavuru M S, Thomassen M J. PU.1 regulation of human alveolar macrophage differentiation requires granulocyte-macrophage colony-stimulating factor. Am J Physiol Lung Cell Mol Physiol 2003; 285: L1132–L1136
   PubMed Web of Science ®Google Scholar
• Reed J A, Ikegami M, Cianciolo E R, Lu W, Cho P S, Hull W, Jobe A H, Whitsett J A. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice. Am J Physiol Lung Cell Mol Physiol 1999; 276: L556–L563
   PubMed Web of Science ®Google Scholar
• Vlahos R, Bozinovski S, Hamilton J A, Anderson G P. Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF). Pharmacol Therapeut 2006; 112: 106–115
   PubMed Web of Science ®Google Scholar
• Ritz S A, Stämpfli M R, Davies D E, Holgate S T, Jordana M. On the generation of allergic airway diseases: from GM–CSF to Kyoto. Trends Immunol 2002; 23: 396–402
   PubMed Web of Science ®Google Scholar
• Wahlstrom J, Berlin M, Skold C M, Wigzell H, Eklund A, Grunewald J. Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis. Thorax 1999; 54: 339–346
   PubMed Web of Science ®Google Scholar
• Nakstad B, Haugen T, Skjonsberg O, Lyberg T. Expression of leukocyte integrins and tissue factor in mononuclear phagocytes. Eur Respir J 1998; 12: 601–606
   PubMed Web of Science ®Google Scholar
• Ward C, Whitford H, Snell G, Bao H, Zheng L, Reid D, Williams T J, Walters E H. Bronchoalveolar lavage macrophage and lymphocyte phenotypes in lung transplant recipients. J Heart Lung Transplant 2001; 20: 1064–1074
   PubMed Web of Science ®Google Scholar
• Skold C M, Lundahl J, Hallden G, Hallgren M, Eklund A. Chronic smoke exposure alters the phenotype pattern and the metabolic response in human alveolar macrophages. Clin Exp Immunol 1996; 106: 108–113
   PubMed Web of Science ®Google Scholar
• Striz I, Wang Y M, Svarcova I, Trnka L, Sorg C, Costabel U. The phenotype of alveolar macrophages and its correlation with immune cells in bronchoalveolar lavage. Eur Respir J 1993; 6: 1287–1294
   PubMed Web of Science ®Google Scholar
• Nicod L P, Joudrier S, Isler P, Spiliopoulos A, Pache J-C. Upregulation of CD40, CD80, CD83 or CD86 on alveolar macrophages after lung transplantation. J Heart Lung Transplant 2005; 24: 1067–1075
   PubMed Web of Science ®Google Scholar
• Van d en, Heuvel M, Tensen C, van As J, Van den Berg T, Fluitsma D, Dijkstra C, Dopp E, Droste A, Van Gaalen F, Sorg C, Hogger P, Beelen R. Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation. J Leukoc Biol 1999; 66: 858–866
   PubMed Web of Science ®Google Scholar
• Porcheray F, Viaud S, Rimaniol A-C, Leone C, Samah B, Dereuddre-Bosquet N, Dormont D, Gras G. Macrophage activation switching: an asset for the resolution of inflammation. Clin Exp Immunol 2005; 142: 481–489
   PubMed Web of Science ®Google Scholar
• Lensmar C, Katchar K, Eklund A, Grunewald J, Wahlström J. Phenotypic analysis of alveolar macrophages and lymphocytes following allergen inhalation by atopic subjects with mild asthma. Respir Med 2006; 100: 918–925
   PubMed Web of Science ®Google Scholar
• Droemann D, Goldmann T, Tiedje T, Zabel P, Dalhoff K, Schaaf B. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients. Respir Res 2005; 6: 68
   PubMed Web of Science ®Google Scholar
• Lin S-M, Frevert C W, Kajikawa O, Wurfel M M, Ballman K, Mongovin S, Wong V A, Selk A, Martin T R. (2004) Differential regulation of membrane CD14 expression and endotoxin-tolerance in alveolar macrophages. Am J Respir Cell Mol Biol 2004; 31: 162–170
   PubMed Web of Science ®Google Scholar
• Colonna M, Facchetti F. TREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses. Journal of Infectious Diseases 2003; 187(Suppl 2)S397–S401
   PubMed Web of Science ®Google Scholar
• Maus U, Herold S, Muth H, Maus R, Ermert L, Ermert M, Weissmann N, Rosseau S, Seeger W, Grimminger F, Lohmeyer J. Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14. Am J Physiol Lung Cell Mol Physiol 2001; 280: L58–L68
   PubMed Web of Science ®Google Scholar
• Mochida-Nishimura K, Surewicz K, Cross J V, Hejal R, Templeton D, Rich E A, Toossi Z. Differential activation of MAP kinase signaling pathways and nuclear factor-kappaB in bronchoalveolar cells of smokers and nonsmokers. Mol Med 2001; 7: 177–85
   PubMed Web of Science ®Google Scholar
• Marwick J A, Kirkham P A, Stevenson C S, Danahay H, Giddings J, Butler K, Donaldson K, MacNee W, Rahman I. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol 2004; 31: 633–642
   PubMed Web of Science ®Google Scholar
• Ferrara F, D'Adda D, Falchi M, Dall'Asta L. The macrophagic activity of patients affected by pneumonia or chronic obstructive pulmonary disease. Int J Tissue React 1996; 18: 109–114
   PubMedGoogle Scholar
• Hodge S, Hodge G, Scicchitano R, Reynolds P N, Holmes M. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol Cell Biol 2003; 81: 289–296
   PubMed Web of Science ®Google Scholar
• Li J, Pritchard D K, Wang X, Park D R, Bumgarner R E, Schwartz S M, Liles W C. cDNA microarray analysis reveals fundamental differences in the expression profiles of primary human monocytes, monocyte-derived macrophages, and alveolar macrophages. J Leukoc Biol 2007; 81: 328–335
   PubMed Web of Science ®Google Scholar