Sustained delivery of timolol maleate from poly(lactic-co-glycolic acid)/poly(lactic acid) microspheres for over 3 months

References

• Alvarez-Lorenzo C, Hiratani H, Gomez-Amoza JL, Martinez-Pacheco R, Souto C, Concheiro A. Soft contact lenses capable of sustained delivery of timolol. J Pharm Sci 2002; 91: 2182–2192
   PubMed Web of Science ®Google Scholar
• Alward WLM. Medical management of glaucoma. N Engl J Med 1998; 339: 1298–1307
   PubMed Web of Science ®Google Scholar
• Alward WLM. A new angle on ocular development. Science 2003; 299: 1527–1528
   PubMed Web of Science ®Google Scholar
• Alward WL, Feldman F, Cashwell LF, Wilensky J, Geijssen HC, Greeve E, Quigley H, Skuta G, Lichter PR, Blondeau P, Anderson DR, Grajewski A, Balazsi G, Amyot M, Levene RZ, Minckler D, Heuer D, Drance SM, Mikelberg F, Douglas G, Johnstone M, Trope G, Hoskins HD, Pollack IP, Mills R, Kasner OP, Schwartz A, Liebmann L, Ritch R, Cohen J, Tuulonen A, Airaksinen PJ, Collaborat Normal-Tens Glaucoma S. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol 1998; 126: 498–505
   PubMed Web of Science ®Google Scholar
• Ayalasomayajula SP, Kompella UB. Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat mode. Eur J Pharmacol 2005; 511: 191–198
   PubMed Web of Science ®Google Scholar
• Blomdahl S, Calissendorff BM, Tengroth B, Wallin O. Blindness in glaucoma patients. Acta Ophthalmol Scand 1997; 75: 589–591
   PubMedGoogle Scholar
• Cui F, Cun DM, Tao AJ, Yang MS, Shi K, Zhao M, Guan Y. Preparation and characterization of melittin-loaded poly (DL-lactic acid) or poly (DL-lactic-co-glycolic acid) microspheres made by the double emulsion method. J Contr Rel 2005; 107: 310–319
   PubMed Web of Science ®Google Scholar
• Friedman DS, Wolfs RCW, O’Colmain B, Klein BE, Taylor HR, West S, Leske C, Mitchell P, Congdon N, Kempen J, Tielsch J. Prevalence of open-angle glaucoma among adults in the United States. Arch Ophthalmol 2004; 122: 532–538
   PubMed Web of Science ®Google Scholar
• Gilbert JA, Simpson AE, Rudnick DE, Geroski DH, Aaberg TM, Edelhauser HF. Transscleral permeability and intraocular concentrations of cisplatin from a collagen matrix. J Cont Rel 2003; 89: 409–417
   PubMed Web of Science ®Google Scholar
• Gurwitz JH, Glynn RJ, Monane M, Everitt DE, Gilden D, Smith N, Avorn J. Treatment for glaucoma – adherence by the elderly. Am J Public Health 1993; 83: 711–716
   PubMed Web of Science ®Google Scholar
• Hiratani H, Alvarez-Lorenzo C. Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid. J Contr Rel 2002; 83: 223–230
   PubMed Web of Science ®Google Scholar
• Huang SF, Chen JL, Yeh MK, Chiang CH. Physicochemical properties and in vivo assessment of timolol-loaded poly(D,L-lactide-co-glycolide) films for long-term intraocular pressure lowering effects. J Ocular Pharmacol Therapeut 2005; 21: 445–453
   PubMed Web of Science ®Google Scholar
• Leske MC, Nemesure B, He Q, Wu SY, Hejtmancik JF, Hennis A. Patterns of open-angle glaucoma in the Barbados Family Study. Ophthalmology 2001; 108: 1015–1022
   PubMed Web of Science ®Google Scholar
• Li S. Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids. J Biomed Mater Res 1999; 48: 342–353
   PubMed Web of Science ®Google Scholar
• Li SM, Garreau H, Vert M. Structure property relationships in the case of the degradation of massive poly(alpha-hydroxy acids) in aqueous-media. 2. Degradation of lactide-glycolide copolymers – Pla37.5ga25 and Pla75ga25. J Mater Sci-Mater Med 1990; 1: 131–139
   Web of Science ®Google Scholar
• Marquis RE, Whitson JT. Management of glaucoma: Focus on pharmacological therapy. Drugs Aging 2005; 22: 1–21
   PubMed Web of Science ®Google Scholar
• Mazzo DJ, Lopper AE. Timolol maleate. Analytical profiles of drug substances, K Florey. Academic Press, London 1987; 641–692
   Google Scholar
• Migdal C, Gregory W, Hitchings R. Long-term functional outcome after early surgery compared with laser and medicine in open-angle glaucoma. Ophthalmology 1994; 101: 1651–1656
   PubMed Web of Science ®Google Scholar
• Mukesh BN, McCarty CA, Rait JL, Taylor HR. Five-year incidence of open-angle glaucoma – the visual impairment project. Ophthalmology 2002; 109: 1047–1051
   PubMed Web of Science ®Google Scholar
• Munier A, Gunning T, Kenny D, O’Keefe M. Causes of blindness in the adult population of the Republic of Ireland. Br J Ophthalmol 1998; 82: 630–633
   PubMed Web of Science ®Google Scholar
• Nihant N, Schugens C, Grandfils C, Jerome R, Teyssie P. Polylactide microparticles prepared by double emulsion-evaporation. 2. Effect of the poly(lactide-co-glycolide) composition on the stability of the primary and secondary emulsions. J Colloid Interf Sci 1995; 173: 55–65
   Web of Science ®Google Scholar
• Park TG. Degradation of poly(lactic-co-glycolic acid) microspheres – effect of copolymer composition. Biomaterials 1995; 16: 1123–1130
   PubMed Web of Science ®Google Scholar
• Patrick M, Mitra AK. Overview of ocular drug delivery and iatrogenic ocular cytopathologies. Ophthalmic drug delivery systems, AK Mitra. Marcel Dekker, New York 1993; 1–27
   Google Scholar
• Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol 1996; 80: 389–393
   PubMed Web of Science ®Google Scholar
• Rotchford AP, Murphy KM. Compliance with timolol treatment in glaucoma. Eye 1998; 12: 234–236
   PubMed Web of Science ®Google Scholar
• Sah HK, Toddywala R, Chien YW. The influence of biodegradable microcapsule formulations on the controlled-release of a protein. J Contr Rel 1994; 30: 201–211
   Web of Science ®Google Scholar
• Schoff EO, Hattenhauer MG, Ing HH, Hodge DO, Kennedy RH, Herman DC, Johnson DH. Estimated incidence of open-angle glaucoma in Olmsted County. Ophthalmology 2001; 108: 882–886
   PubMed Web of Science ®Google Scholar
• Schuman JS. Antiglaucoma medications: A review of safety and tolerability issues related to their use. Clin Therapeut 2000; 22: 167–208
   PubMed Web of Science ®Google Scholar
• Sezer AD, Akbuga J. Release characteristics of chitosan treated alginate beads: II. Sustained release of a low molecular drug from chitosan treated alginate beads. J Microencapsulation 1999; 16: 687–696
   PubMed Web of Science ®Google Scholar
• Shedden A, Laurence J, Tipping R. Efficacy and tolerability of timolol maleate ophthalmic gel-forming solution versus timolol ophthalmic solution in adults with open-angle glaucoma or ocular hypertension: A six-month. Clin Therapeut 2001; 23: 440–450
   PubMed Web of Science ®Google Scholar
• Uusitalo H, Nino J, Tahvanainen K, Turjanmaa V, Ropo A, Tuominen J, Kahonen M. Efficacy and systemic side-effects of topical 0.5% timolol aqueous solution and 0.1% timolol hydrogel. Acta Ophthalmol Scand 2005; 83: 723–728
   PubMedGoogle Scholar
• Wang N, Qiu JS, Wu XS. Tailored polymeric materials for controlled delivery systems. ACS Symposium Series 709, I McCulloch, SW Shalaby. ACS, Washington, DC 1998; 242–254
   Google Scholar
• Wilson RP, Kanal N, Spaeth GL. Timolol – its effectiveness in different types of glaucoma. Ophthalmology 1979; 86: 43–50
   PubMed Web of Science ®Google Scholar
• Worakul N, Robinson JR. Ocular pharmacokinetics/pharmacodynamics. Eur J Pharm Biopharm 1997; 44: 71–83
   Web of Science ®Google Scholar
• Yan CH, Resau JH, Hewetson J, West M, Rill WL, Kende M. Characterization and morphological analysis of protein-loaded poly(lactide-co-glycolide) microparticles prepared by water-in oil-in-water emulsion technique. J Contr Rel 1994; 32: 231–241
   Web of Science ®Google Scholar
• Zimmerman TJ, Kaufman HE. Beta-adrenergic blocking-agent for treatment of glaucoma. Arch Ophthalmol 1977; 95: 601–604
   PubMed Web of Science ®Google Scholar