Development, optimization and in vitro evaluation of alginate mucoadhesive microspheres of carvedilol for nasal delivery

References

• Al-Ghananeem AM, Sandefer EP, Doll WJ, Page RC, Chang Y, Digenis GA. Gamma scintigraphy for testing bioequivalence: A case study on two cromolyn sodium nasal spray preparations. Int J Pharm 2008, doi:10.1016/j.ijpharm.2008.01.040
   PubMed Web of Science ®Google Scholar
• Bechgaard E, Gizurarson S, Hjortkjaer RK. Pharmacokinetic and pharmacodynamic response after intranasal administration of diazepam to rabbits. J Pharm Pharmacol 1997; 49: 747–750
   PubMed Web of Science ®Google Scholar
• Bhardwaj SB, Shukla AJ, Collins CC. Effect of varying drug loading on particle size distribution and drug release kinetics of verapamil hydrochloride microspheres prepared with cellulose esters. J Microencapsulation 1995; 12: 71–81
   PubMed Web of Science ®Google Scholar
• Chan LW, Heng PWS. Effects of aldehydes and methods of cross-linking on properties of calcium alginate microspheres prepared by emulsification. Biomaterials 2002; 23: 1319–1326
   PubMed Web of Science ®Google Scholar
• Chan LW, Jin Y, Heng PWS. Cross-linking mechanisms of calcium and zinc in production of alginate microspheres. Int J Pharm 2002; 242: 255–258
   PubMed Web of Science ®Google Scholar
• Chavanpatil MD, Vavia PR. The influence of absorption enhancers on nasal absorption of acyclovir. Eur J Pharm Biopharm 2004; 57: 483–487
   PubMed Web of Science ®Google Scholar
• Cho NH, Seong SY, Chun KH, Kim YH, Chan Kwon I, Ahn BY, et al. Novel mucosal immunization with polysaccharide–protein conjugates entrapped in alginate microspheres. J Contr Rel 1998; 53: 215–224
   PubMed Web of Science ®Google Scholar
• Daley-Yates PT, Baker RC. Systemic bioavailability of fluticasone propionate administered as nasal drops and aqueous nasal spray formulations. Br J Clin Pharmacol 2001; 51: 103–105
   PubMed Web of Science ®Google Scholar
• Dhiman MK, Yedurkar PD, Sawant KK. Buccal bioadhesive delivery system of 5-fluorouracil: Optimization and characterization. Drug Dev Ind Pharm 2008; 34: 761–770
   PubMed Web of Science ®Google Scholar
• Emmerichs N, Wingender J, Flemming HC, Mayer C. Interaction between alginates and manganese cations: Identification of preferred cation binding sites. Int J Biol Macromol 2004; 34: 73–79
   PubMed Web of Science ®Google Scholar
• Fundueanu G, Constantin M, Dalpiaz A, Bortolotti F, Cortesi R, Ascenzi P, et al. Preparation and characterization of starch/cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy®) in allergic rhinitis treatment. Biomaterials 2004; 25: 159–170
   PubMed Web of Science ®Google Scholar
• Fundueanu G, Esposito E, Mihai D, Carpov A, Desbrieres J, Rinaudo M, et al. Preparation and characterization of calcium alginate microspheres by a new emulsification method. Int J Pharm 1998; 170: 11–21
   Web of Science ®Google Scholar
• Gonzalez Ferreiro M, Tillman LG, Hardee G, Bumpier R. Alginate/poly-l-lysine microparticles for the intestinal delivery of antisense oligonucleotides. Pharm Res 2002; 19: 755–764
   PubMed Web of Science ®Google Scholar
• Gonzalez-Rodrıguez ML, Holgado MA, Sanchez-Lafuente C, Rabasco AM, Fini A. Alginate/chitosan particulate systems for sodium diclofenac release. Int J Pharm 2002; 232: 225–234
   PubMed Web of Science ®Google Scholar
• Grant GT, Morris ER, Rees DA, Smith PJC, Thom D. Biological interactions between polysaccharides and divalent cations: The egg-box model. FEBS Lett 1973; 32: 195–198
   Web of Science ®Google Scholar
• Gursoy A, Karakus D, Okar I. Polymers for sustained release formulations of dipyridamole-alginate microspheres and tabletted microspheres. J Microencapsulation 1999; 16: 439–452
   PubMed Web of Science ®Google Scholar
• Harris AS, Ohlin M, Svensson E, Lethagen S, Nilsson IM. Effect of viscosity on the pharmacokinetics and biological response to intranasal desmopressin. J Pharm Sci 2006; 78: 470–471
   Web of Science ®Google Scholar
• Heng PWS, Chan LW, Wong TW. Formation of alginate microspheres using emulsification technique. J Microencapsulation 2003; 20: 401–413
   PubMed Web of Science ®Google Scholar
• Huang YB, Tsai YH, Lee SH, Chang JS, Wu PC. Optimization of pH-independent release of nicardipine hydrochloride extended-release matrix tablets using response surface methodology. Int J Pharm 2005; 289: 87–95
   PubMed Web of Science ®Google Scholar
• Hussain A, Hirai S, Bawarshi R. Nasal absorption of propranolol from different dosage forms by rats and dogs. J Pharm Sci 1980; 69: 1411–1413
   PubMed Web of Science ®Google Scholar
• Hwang JJ, Ko YP, Jen RK, Hsu YW, Cheng CR, Wei TT, et al. The use of intranasal nitroglycerin to prevent pressor responses during intubation in general anesthesia—A comparison of various doses. Acta Anaesthesiol Sin 1995; 33: 205–210
   PubMedGoogle Scholar
• Illum L. Nasal drug delivery: Problems, possibilities and solutions. J Contr Rel 2003; 87: 187–198
   PubMed Web of Science ®Google Scholar
• Illum L, Jorgensen H, Bisgaard H, Krogsgaard O, Rossing N. Bioadhesive microspheres as a potential nasal drug delivery system. Int J Pharm 1987; 39: 189–199
   Web of Science ®Google Scholar
• Kincl M, Turk S, Vrecer F. Application of experimental design methodology in development and optimization of drug release method. Int J Pharm 2005; 291: 39–49
   PubMed Web of Science ®Google Scholar
• Kinoshita R, Ishida K, Sendaya K, Miyagawa A, Oda S, Taniguchi K, et al. Clinical evaluation of isosorbide dinitrate (ISDN) spray: A study on the plasma concentrations of ISDN and on its hemodynamic effects using three administration routes. Masui 1990; 39: 1660–1663
   PubMedGoogle Scholar
• Kubota R, Komiyama T, Shimada H. Evaluation of the method for nifedipine administration for a rapid onset of clinical effect: A clinical study in normal volunteers. Yakugaku Zasshi 2001; 121: 355–364
   PubMed Web of Science ®Google Scholar
• Landau AJ, Eberhardt RT, Frishman WH. Intranasal delivery of cardiovascular agents: An innovative approach to cardiovascular pharmacotherapy. Am Heart J 1994; 127: 1594–1599
   PubMed Web of Science ®Google Scholar
• Lucinda-Silva RM, Evangelista RC. Microspheres of alginate–chitosan containing isoniazid. J Microencapsulation 2003; 20: 145–152
   PubMed Web of Science ®Google Scholar
• Majithiya RJ, Murthy RSR. Chitosan-based mucoadhesive microspheres of clarithromycin as a delivery system for antibiotic to stomach. Curr Drug Del 2005; 2: 235–242
   PubMedGoogle Scholar
• Mao S, Chen J, Wei Z, Liu H, Bi D. Intranasal administration of melatonin starch microspheres. Int J Pharm 2004; 272: 37–43
   PubMed Web of Science ®Google Scholar
• Martınez-Sancho C, Herrero-Vanrell R, Negro S. Optimization of aciclovir poly(D,L-lactide-co-glycolide) microspheres for intravitreal administration using a factorial design study. Int J Pharm 2004; 273: 45–56
   PubMed Web of Science ®Google Scholar
• Martin S, Sarmento B, Souto EB, Ferreira DC. Insulin-loaded alginate microspheres for oral delivery—Effect of polysaccharide reinforcement on physicochemical properties and release profile. Carbohydr Polym 2007; 69: 725–731
   Web of Science ®Google Scholar
• Mehta AK, Yadav KS, Sawant KK. Nimodipine loaded PLGA nanoparticles: Formulation optimization using factorial design, characterization and in vitro evaluation. Curr Drug Del 2007; 4: 185–193
   PubMedGoogle Scholar
• Mladenovska K, Raicki RS, Janevik EI, Ristoki T, Pavlova MJ, Kavrakovski Z, et al. Colon-specific delivery of 5-aminosalicylic acid from chitosan-Ca-alginate microparticles. Int J Pharm 2007; 342: 124–136
   PubMed Web of Science ®Google Scholar
• Muramatsu K, Maitani Y, Takayama K, Nagai T. The relationship between the rigidity of the liposomal membrane and the absorption of insulin after nasal administration of liposomes modified with an enhancer containing insulin in rabbits. Drug Dev Ind Pharm 1999; 25: 1099–1105
   PubMed Web of Science ®Google Scholar
• Narendra C, Srinath MS, Prakash Rao B. Development of three layered buccal compact containing metoprolol tartrate by statistical optimization technique. Int J Pharm 2005; 304: 102–114
   PubMed Web of Science ®Google Scholar
• Packer M, Coats AJS, Fowler MB, Katus HA, Henry Krum MB, Paul M, et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure. Circulation 2002; 106: 2194–2199
   PubMed Web of Science ®Google Scholar
• Patil SB, Murthy RSR. Preparation and in vitro evaluation of mucoadhesive chitosan microspheres of amlodipine besylate for nasal administration. Ind J Pharm Sci 2006; 8: 64–67
   Google Scholar
• Peppas NA, Buri PA. Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues. J Contr Rel 1985; 2: 257–275
   Google Scholar
• Pisal SS, Paradkar AR, Mahadik KR, Kadam SS. Pluronic gels for nasal delivery of vitamin B12. Part I: Preformulation study. Int J Pharm 2004; 270: 37–45
   PubMed Web of Science ®Google Scholar
• Rajanikanth PS, Sankar C, Mishra B. Sodium alginate microspheres of metoprolol tartrate for intranasal systemic delivery: Development and evaluation. Drug Del 2003; 10: 21–28
   PubMed Web of Science ®Google Scholar
• Ranga Rao KV, Buri P. A novel in situ method to test polymer and coated microparticles for bioadhesion. Int J Pharm 1989; 52: 265–270
   Web of Science ®Google Scholar
• Rastogi R, Sultana Y, Aqil M, Ali A, Kumar S, Chuttani K, et al. Alginate microspheres of isoniazid for oral sustained drug delivery. Int J Pharm 2007; 334: 71–77
   PubMed Web of Science ®Google Scholar
• Ritger PL, Peppas NA. A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Contr Rel 1987; 5: 37–42
   Google Scholar
• Serp D, Cantana E, Heinzen C, Stockar UV, Marison IW. Characterization of an encapsulation device for the production of monodisperse alginate beads for cell immobilization. Biotech Bioeng 2000; 70: 41–53
   PubMed Web of Science ®Google Scholar
• Singh B, Ahuja N. Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: Optimization of bioadhesion, dissolution, and diffusion parameters. Drug Dev Ind Pharm 2002; 28: 431–442
   PubMed Web of Science ®Google Scholar
• Thummel KE, Shen DD. Design and optimization of dosage regimens: Pharmacokinetic data. Goodman and Gilman's The pharmacological basis of therapeutics. 10th ed, JG Hardman, LE Limbirel, AG Gilman. McGraw Hill, New York 2001; 1936–1940
   Google Scholar
• Vandenberg GW, Drolet C, Scout SL, de la Noue J. Factors affecting protein release from alginate–chitosan coacervate microcapsules during production and gastric/intestinal simulation. J Contr Rel 2001; 77: 297–307
   PubMed Web of Science ®Google Scholar
• Vandervoort J, Ludwig A. Preparation factors affecting the properties of polylactide nanoparticles: A factorial design study. Pharmazie. 2001; 56: 484–488
   PubMed Web of Science ®Google Scholar
• Varshosaz J, Sadrai H, Heidari A. Nasal delivery of insulin using bioadhesive chitosan gels. Drug Del 2006; 13: 31–38
   PubMed Web of Science ®Google Scholar
• Vyas SP, Goswami SK, Singh R. Liposomes based nasal delivery system of nifedipine: Development and characterization. Int J Pharm 1995; 118: 23–30
   Web of Science ®Google Scholar
• Wan LSC, Heng PWS, Chan LW. Drug encapsulation in alginate microspheres by emulsification. J Microencapsulation 1992; 9: 309–316
   PubMed Web of Science ®Google Scholar
• Wan LSC, Heng PWS, Chan LW. Surfactant effects on alginate microspheres. Int J Pharm 1994; 103: 267–275
   Web of Science ®Google Scholar