231
Views
24
CrossRef citations to date
0
Altmetric
Original

Delivery of rSLPI in a liposomal carrier for inhalation provides protection against cathepsin L degradation

, , &
Pages 513-522 | Published online: 21 Aug 2009

References

  • Adcock IM. Steroid resistance in asthma. Molecular mechanisms. Am J Respir Crit Care Med 1996; 154: S58–S61
  • Amselem S, Gabizon A, Barenholz Y. Optimization and upscaling of doxorubicin-containing liposomes for clinical use. J Pharm Sci 1990; 79: 1045–1052
  • Barrios VE, Middleton SC, Kashem MA, Havill AM, Toombs CF, Wright CD. Tryptase mediates hyperresponsiveness in isolated guinea pig bronchi. Life Sci 1998; 63: 2295–2303
  • Bergenfeldt M, Bjork P, Ohlsson K. The elimination of secretory leukocyte protease inhibitor (SLPI) after intravenous injection in dog and man. Scand J Clin Lab Invest 1990; 50: 729–737
  • Bhattacharya S, Haldar S. The effects of cholesterol inclusion on the vesicular membranes of cationic lipids. Biochim Biophys Acta 1996; 1283: 21–30
  • Bhavane R, Karathanasis E, Annapragada AV. Agglomerated vesicle technology: A new class of particles for controlled and modulated pulmonary drug delivery. J Contr Rel 2003; 93: 15–28
  • Bi R, Zhang N. Liposomes as a carrier for pulmonary delivery of peptides and proteins. J Biomed Nanotechnol 2007; 3: 332
  • Bridges P, Taylor KMG. Nebulisers for the generation of liposomal aerosols. Int J Pharm 1998; 173: 117–125
  • Clark JM, Whitney RR, Olsen SJ, George RJ, Swerdel MR, Kunselman L, et al. Amphotericin B lipid complex therapy of experimental fungal infections in mice. Antimicrob Agents Chemother 1991; 35: 615–621
  • Couvreur P, Fattal E, Andremont A. Liposomes and nanoparticles in the treatment of intracellular bacterial infections. Pharm Res 1991; 8: 1079–1086
  • de Haan A, Groen G, Prop J, van Rooijen N, Wilschut J. Mucosal immunoadjuvant activity of liposomes: Role of alveolar macrophages. Immunology 1996; 89: 488–493
  • Elhissi AM, Faizi M, Naji WF, Gill HS, Taylor KM. Physical stability and aerosol properties of liposomes delivered using an air-jet nebulizer and a novel micropump device with large mesh apertures. Int J Pharm 2007; 334: 62–70
  • Fan M, Xu S, Xia S, Zhang X. Effect of different preparation methods on physicochemical properties of salidroside liposomes. J Agric Food Chem 2007; 55: 3089–3095
  • Fogh J, Fogh JM, Orfeo T. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst 1977; 59: 221–226
  • Forteza RM, Ahmed A, Lee T, Abraham WM. Secretory leukocyte protease inhibitor, but not alpha-1 protease inhibitor, blocks tryptase-induced bronchoconstriction. Pulm Pharmacol Ther 2001; 14: 107–110
  • Freise CE, Liu T, Hong K, Osorio RW, Papahadjopoulos D, Ferrell L, et al. The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome. Transplantation 1994; 57: 928–932
  • Fryksmark U, Ohlsson K, Polling A, Tegner H. Distribution of antileukoprotease in upper respiratory mucosa. Ann Otol Rhinol Laryngol 1982; 91: 268–271
  • Garg M, Dutta T, Jain NK. Stability study of stavudine-loaded O-palmitoyl-anchored carbohydrate-coated liposomes. AAPS PharmSciTech 2007; 8: Article 38
  • Gavalda J, Martin MT, Lopez P, Gomis X, Ramirez JL, Rodriguez D, et al. Efficacy of nebulized liposomal amphotericin B in treatment of experimental pulmonary aspergillosis. Antimicrob Agents Chemother 2005; 49: 3028–3030
  • Gavalda J, Martin T, Lopez P, Gomis X, Ramirez JL, Rodriguez D, et al. Efficacy of high loading doses of liposomal amphotericin B in the treatment of experimental invasive pulmonary aspergillosis. Clin Microbiol Infect 2005; 11: 999–1004
  • Gillissen A, Birrer P, McElvaney NG, Buhl R, Vogelmeier C, Hoyt RF, Jr, et al. Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid. J Appl Physiol 1993; 75: 825–832
  • Greene CM, McElvaney NG, O’Neill SJ, Taggart CC. Secretory leucoprotease inhibitor impairs Toll-like receptor 2- and 4-mediated responses in monocytic cells. Infect Immun 2004; 72: 3684–3687
  • Griffiths GD, Phillips GJ, Bailey SC. Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation. Vaccine 1999; 17: 2562–2568
  • Gruber SA, Venkataram S, Canafax DM, Cipolle RJ, Bowers L, Elsberry D, McGuiggan D, Hynes PE, Ritz JA, Gould FH, Matas A, Hrushesky WJM, Rahman YE. Liposomal formulation eliminates acute toxicity and pump incompatibility of parenteral cyclosporine. Pharm Res 1989; 6: 601–607
  • Huang YY, Wang CH. Pulmonary delivery of insulin by liposomal carriers. J Contr Rel 2006; 113: 9–14
  • Jin FY, Nathan C, Radzioch D, Ding A. Secretory leukocyte protease inhibitor: A macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell 1997; 88: 417–426
  • Keatings VM, Jatakanon A, Worsdell YM, Barnes PJ. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997; 155: 542–548
  • Khanna C, Hasz DE, Klausner JS, Anderson PM. Aerosol delivery of interleukin 2 liposomes is nontoxic and biologically effective: Canine studies. Clin Cancer Res 1996; 2: 721–734
  • Kottyan LC, Collier AR, Niese KA, Radu CO, Witte ON, Rothenberg ME, et al. Eosinophils respond to acidic environments with cAMP generation in a TDAG8-dependent manner. J Allergy Clin Immunol 2007; 119: S217
  • Lasic DD. Novel applications of liposomes. Trends Biotechnol 1998; 16: 307–321
  • Lentsch AB, Jordan JA, Czermak BJ, Diehl KM, Younkin EM, Sarma V, et al. Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation. Am J Pathol 1999; 154: 239–247
  • Letsou GV, Safi HJ, Reardon MJ, Ergenoglu M, Li Z, Klonaris CN, et al. Pharmacokinetics of liposomal aerosolized cyclosporine A for pulmonary immunosuppression. Ann Thorac Surg 1999; 68: 2044–2048
  • Lutwyche P, Cordeiro C, Wiseman DJ, St-Louis M, Uh M, Hope MJ, et al. Intracellular delivery and antibacterial activity of gentamicin encapsulated in pH-sensitive liposomes. Antimicrob Agents Chemother 1998; 42: 2511–2520
  • Malvern Instruments Ltd. 2003. HPPS Operators Guide Man0314 Issue 2.0.: Malvern Instruments Ltd. New York: Dover Publications Inc. p A.1.
  • Manosroi A, Podjanasoonthon K, Manosroi J. Stability and release of topical tranexamic acid liposome formulations. J Cosmet Sci 2002; 53: 375–386
  • McCullough HN, Juliano RL. Organ-selective action of an antitumor drug: Pharmacologic studies of liposome-encapsulated beta-cytosine arabinoside administered via the respiratory system of the rat. J Natl Cancer Inst 1979; 63: 727–731
  • McElvaney NG, Doujaiji B, Moan MJ, Burnham MR, Wu MC, Crystal RG. Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis. Am Rev Respir Dis 1993; 148: 1056–1060
  • McElvaney NG, Nakamura H, Birrer P, Hebert CA, Wong WL, Alphonso M, et al. Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor. J Clin Invest 1992; 90: 1296–1301
  • McMullen TP, Lewis RN, McElhaney RN. Differential scanning calorimetric study of the effect of cholesterol on the thermotropic phase behavior of a homologous series of linear saturated phosphatidylcholines. Biochemistry 1993; 32: 516–522
  • McNeely TB, Dealy M, Dripps DJ, Orenstein JM, Eisenberg SP, Wahl SM. Secretory leukocyte protease inhibitor: A human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro. J Clin Invest 1995; 96: 456–464
  • Mehnert W, Mader K. Solid lipid nanoparticles: Production, characterization and applications. Adv Drug Deliv Rev 2001; 47: 165–196
  • Mooren HW, Kramps JA, Franken C, Meijer CJ, Dijkman JA. Localisation of a low-molecular-weight bronchial protease inhibitor in the peripheral human lung. Thorax 1983; 38: 180–183
  • Morimoto Y, Adachi Y. Pulmonary uptake of liposomal phosphatidylcholine upon intratracheal administration to rats. Chem Pharm Bull (Tokyo) 1982; 30: 2248–2251
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55–63
  • Niven RW. Delivery of biotherapeutics by inhalation aerosol. Crit Rev Ther Drug Carrier Syst 1995; 12: 151–231
  • Niven RW, Schreier H. Nebulization of liposomes. I. Effects of lipid composition. Pharm Res 1990; 7: 1127–1133
  • Niven RW, Speer M, Schreier H. Nebulization of liposomes. II. The effects of size and modeling of solute release profiles. Pharm Res 1991; 8: 217–221
  • Saari SM, Vidgren MT, Koskinen MO, Turjanmaa VM, Waldrep JC, Nieminen MM. Regional lung deposition and clearance of 99mTc-labeled beclomethasone-DLPC liposomes in mild and severe asthma. Chest 1998; 113: 1573–1579
  • Stewart JC. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal Biochem 1980; 104: 10–14
  • Stolk J, Camps J, Feitsma HI, Hermans J, Dijkman JH, Pauwels EK. Pulmonary deposition and disappearance of aerosolised secretory leucocyte protease inhibitor. Thorax 1995; 50: 645–650
  • Suarez S, Hickey AJ. Drug properties affecting aerosol behavior. Respir Care 2000; 45: 652–666
  • Sundstrom C, Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 1976; 17: 565–577
  • Swallow CJ, Grinstein S, Rotstein OD. Lipopolysaccharide impairs macrophage cytoplasmic pH regulation under conditions simulating the inflammatory microenvironment. J Leukoc Biol 1992; 52: 395–399
  • Taggart C, Cervantes-Laurean D, Kim G, McElvaney NG, Wehr N, Moss J, et al. Oxidation of either methionine 351 or methionine 358 in alpha 1-antitrypsin causes loss of anti-neutrophil elastase activity. J Biol Chem 2000; 275: 27258–27265
  • Taggart CC, Greene CM, McElvaney NG, O’Neill S. Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination. J Biol Chem 2002; 277: 33648–33653
  • Taggart CC, Lowe GJ, Greene CM, Mulgrew AT, O’Neill SJ, Levine RL, et al. Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor. J Biol Chem 2001; 276: 33345–33352
  • Takahashi H, Ishidoh K, Muno D, Ohwada A, Nukiwa T, Kominami E, et al. Cathepsin L activity is increased in alveolar macrophages and bronchoalveolar lavage fluid of smokers. Am Rev Respir Dis 1993; 147: 1562–1568
  • Takeyabu K, Betsuyaku T, Nishimura M, Yoshioka A, Tanino M, Miyamoto K, et al. Cysteine proteinases and cystatin C in bronchoalveolar lavage fluid from subjects with subclinical emphysema. Eur Respir J 1998; 12: 1033–1039
  • Taylor KM, Taylor G, Kellaway IW, Stevens J. The influence of liposomal encapsulation on sodium cromoglycate pharmacokinetics in man. Pharm Res 1989; 6: 633–636
  • Taylor KMG, Taylor G, Kellaway IW, Stevens J. The stability of liposomes to nebulisation. Int J Pharm 1990; 58: 57–61
  • Vogelmeier C, Buhl R, Hoyt RF, Wilson E, Fells GA, Hubbard RC, et al. Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium. J Appl Physiol 1990; 69: 1843–1848
  • Vogelmeier C, Gillissen A, Buhl R. Use of secretory leukoprotease inhibitor to augment lung antineutrophil elastase activity. Chest 1996; 110(6 Suppl)261S–266S
  • Wagner A, Vorauer-Uhl K, Katinger H. Nebulization of liposomal rh-Cu/Zn-SOD with a novel vibrating membrane nebulizer. J Liposome Res 2006; 16: 113–125
  • Wright CD, Havill AM, Middleton SC, Kashem MA, Lee PA, Dripps DJ, et al. Secretory leukocyte protease inhibitor prevents allergen-induced pulmonary responses in animal models of asthma. J Pharmacol Exp Ther 1999; 289: 1007–1014
  • Wyde PR, Six HR, Wilson SZ, Gilbert BE, Knight V. Activity against rhinoviruses, toxicity, and delivery in aerosol of enviroxime in liposomes. Antimicrob Agents Chemother 1988; 32: 890–895
  • Yang J, Zhu J, Sun D, Ding A. Suppression of macrophage responses to bacterial lipopolysaccharide (LPS) by secretory leukocyte protease inhibitor (SLPI) is independent of its anti-protease function. Biochim Biophys Acta 2005; 1745: 310–317
  • Yohannes G, Pystynen KH, Riekkola ML, Wiedmer SK. Stability of phospholipid vesicles studied by asymmetrical field-flow fractionation and capillary electrophoresis. Anal Chim Acta 2006; 560: 50–56
  • Zhang Y, DeWitt DL, McNeely TB, Wahl SM, Wahl LM. Secretory leukocyte protease inhibitor suppresses the production of monocyte prostaglandin H synthase-2, prostaglandin E2, and matrix metalloproteinases. J Clin Invest 1997; 99: 894–900

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.