Influence of polyvinylpyrrolidone quantity on the solubility, crystallinity and oral bioavailability of fenofibrate in solvent-evaporated microspheres

References

• Dave RH, Patel HH, Donahue E, Patel AD. To evaluate the change in release from solid dispersion using sodium lauryl sulfate and model drug sulfathiazole. Drug Dev Ind Pharm, 2013;39(10):1562–72.
   PubMed Web of Science ®Google Scholar
• Goddeeris C, Coacci J, Vanden Mooter G. Correlation between digestion of the lipid phase of smedds and release of the anti-HIV drug UC 781 and the anti-mycotic drug enilconazole from smedds. Eur J Pharm Biopharm, 2007;66(2):173–81.
   PubMed Web of Science ®Google Scholar
• Gupta P, Kakumanu VK, Bansal AK. Stability and solubility of celecoxib-PVP amorphous dispersions: A molecular perspective. Pharm Res, 2004;21(10):1762–9.
   PubMed Web of Science ®Google Scholar
• Ha ES, Kim JS, Baek I, Hwang SJ, Kim MS. Enhancement of dissolution and bioavailability of ezetimibe by amorphous solid dispersion nanoparticles fabricated using supercritical antisolvent process. J Pharm Invest, 2015;45(7):641–9.
   Google Scholar
• He H, Yang R, Tang X. In vitro and in vivo evaluation of fenofibrate solid dispersion prepared by hot-melt extrusion. Drug Dev Ind Pharm, 2010;36(6):681–7.
   PubMed Web of Science ®Google Scholar
• Hugo M, Kunath K, Dressman J. Selection of excipient, solvent and packaging to optimize the performance of spray-dried formulations: Case example fenofibrate. Drug Dev Ind Pharm, 2013;39(2):402–12.
   PubMed Web of Science ®Google Scholar
• Joe JH, Lee WM, Park YJ, Joe KH, Oh DH, Seo YG, Woo JS, Yong CS, Choi HG. Effect of the solid-dispersion method on the solubility and crystalline property of tacrolimus. Int J Pharm, 2010;395(1-2):161–6.
   PubMed Web of Science ®Google Scholar
• Kim DW, Kwon MS, Yousaf AM, Balakrishnan P, Park JH, Kim DS, Lee BJ, Park YJ, Yong CS, Kim JO. Comparison of a solid SMEDDS and solid dispersion for enhanced stability and bioavailability of clopidogrel napadisilate. Carbohydr Polym, 2014;114:365–74.
   PubMed Web of Science ®Google Scholar
• Kim GG, Poudel BK, Marasini N, Lee DW, Hiep TT, Yang KY, Kim JO, Yong CS, Choi HG. Enhancement of oral bioavailability of fenofibrate by solid self-microemulsifying drug delivery systems. Drug Dev Ind Pharm, 2013;39(9):1431–8.
   PubMed Web of Science ®Google Scholar
• Kim KS, Jin SG, Mustapha O, Yousaf AM, Kim DW, Kim YH, Kim JO, Yong CS, Woo JS, Choi HG. Novel fenofibric acid-loaded controlled release pellet bioequivalent to choline fenofibrate-loaded commercial product in beagle dogs. Int J Pharm, 2015;490:273–80.
   PubMed Web of Science ®Google Scholar
• Konno H, Handa T, Alonzo DE, Taylor LS. Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine. Eur J Pharm Biopharm, 2008;70(2):493–9.
   PubMed Web of Science ®Google Scholar
• Lee DW, Marasini N, Poudel BK, Kim JH, Cho HJ, Moon BK, Choi HG, Yong CS, Kim JO. Application of Box–Behnken design in the preparation and optimization of fenofibrate-loaded self-microemulsifying drug delivery system (SMEDDS). J Microencapsul, 2014;31(1):31–40.
   PubMed Web of Science ®Google Scholar
• Lee SN, Poudel BK, Tran TH, Marasini N, Pradhan R, Im Lee Y, Lee DW, Woo JS, Choi HG, Yong CS. A novel surface-attached carvedilol solid dispersion with enhanced solubility and dissolution. Arch Pharm Res, 2013;36:79–85.
   PubMed Web of Science ®Google Scholar
• Modi A, Tayade P. Enhancement of dissolution profile by solid dispersion (kneading) technique. AAPS Pharm Sci Tech, 2006;7(3):E87–92.
   PubMed Web of Science ®Google Scholar
• Oh DH, Din FU, Kim DW, Kim JO, Yong CS, Choi HG. Flurbiprofen-loaded nanoparticles prepared with polyvinylpyrrolidone using Shirasu porous glass membranes and a spray-drying technique: Nano-sized formation and improved bioavailability. J Microencapsul, 2013;30:674–80.
   PubMed Web of Science ®Google Scholar
• Pradhan R, Lee DW, Choi HG, Yong CS, Kim JO. Fabrication of a uniformly sized fenofibrate microemulsion by membrane emulsification. J Microencapsul, 2013;30(1):42–8.
   PubMed Web of Science ®Google Scholar
• Rashid R, Kim DW, Din FU, Mustapha O, Yousaf AM, Park JH, Kim JO, Yong CS, Choi HG. Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion. Carbohydr Polym, 2015;130:26–31.
   PubMed Web of Science ®Google Scholar
• Tang N, Lai J, Chen Y, Lu Y, Wu W. Fenofibrate solid dispersion pellets prepared by fluid-bed coating: Physical characterization, improved dissolution and oral bioavailability in beagle dogs. J Chin Pharm Sci, 2009;18(2):156–61.
   Google Scholar
• Tanno F, Nishiyama Y, Kokubo H, Obara S. Evaluation of hypromellose acetate succinate (HPMCAS) as a carrier in solid dispersions. Drug Dev Ind Pharm, 2004;30(1):9–17.
   PubMed Web of Science ®Google Scholar
• Tran TH, Ramasamy T, Truong DH, Choi HG, Yong CS, Kim JO. Preparation and characterization of fenofibrate-loaded nanostructured lipid carriers for oral bioavailability enhancement. AAPS PharmSciTech, 2014;15(6):1509–15.
   PubMed Web of Science ®Google Scholar
• Yang KY, Du HH, Yousaf AM, Kim DW, Shin YJ, Bae ON, Kim YI, Kim JO, Yong CS, Choi HG. Silymarin-loaded solid nanoparticles provide excellent hepatic protection: Physicochemical characterization and in vivo evaluation. Int J Nanomedicine, 2013;8:3333–43.
   PubMed Web of Science ®Google Scholar
• Yousaf AM, Kim DW, Choi HG, Oh E. Validation of a highly sensitive RP-HPLC method for quantification of fenofibrate in pure and pharmaceutical dosage forms. Curr Pharm Anal, 2014;10(2):97–104.
   Web of Science ®Google Scholar
• Yousaf AM, Kim DW, Cho KH, Kim JO, Yong CS, Choi HG. Effect of the preparation method on crystallinity, particle size, aqueous solubility and dissolution of different samples of the poorly water-soluble fenofibrate with HP-β-CD. J Incl Phenom Macrocycl Chem, 2015a;81:347–56.
   Web of Science ®Google Scholar
• Yousaf AM, Kim DW, Kim JO, Chang PS, Baek HH, Lim SJ, Cho KH, Yong CS, Choi HG. Characterization of physicochemical properties of spray-dried solid dispersions loaded with unmodified crystalline fenofibrate. Curr Pharm Anal, 2015b;11(2):139–44.
   Web of Science ®Google Scholar
• Yousaf AM, Kim DW, Oh YK, Yong CS, Kim JO, Choi HG. Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: Physicochemical characterization and in vivo investigation. Int J Nanomedicine, 2015c;10:1819–30.
   PubMed Web of Science ®Google Scholar
• Yousaf AM, Mustapha O, Kim DW, Kim DS, Kim KS, Jin SG, Yong CS, Youn YS, Oh YK, Kim JO, Choi HG. Novel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate. Int J Nanomedicine, 2016;11:213–21.
   PubMed Web of Science ®Google Scholar
• Xu W, Lee MK. Development and evaluation of lipid nanoparticles for paclitaxel delivery: A comparison between solid lipid nanoparticles and nanostructured lipid carriers. J Pharm Invest, 2015;45(7):675–80.
   Google Scholar