References
- Abdelhamid, A.M., EL Deeb, M., and Zaafan, M.A., 2022. The protective effect of xanthenone against LPS-induced COVID-19 acute respiratory distress syndrome (ARDS) by modulating the ACE2/Ang-1-7 signaling pathway. European review for medical and pharmacological sciences, 26 (14), 5285–5296. doi: 10.26355/eurrev_202207_29320.
- Abdelhamid, A.M., Selim, A., and Zaafan, M.A., 2021. The hepatoprotective effect of piperine against thioacetamide-induced liver fibrosis in mice: the involvement of miR-17 and TGF-β/Smads pathways. Frontiers in molecular biosciences, 8, 754098. doi: 10.3389/fmolb.2021.754098.
- Abdel-Nasser, Z.M., Zaafan, M.A., and Abdelhamid, A.M., 2023. Modulation of the miR-122/Sirt-6/ACE2 axis on experimentally-induced myocardial infarction. Chemico-biological interactions, 369, 110276. doi: 10.1016/j.cbi.2022.110276.
- Ayeldeen, G., et al., 2024. The impact of lncRNA-GAS5/miRNA-200/ACE2 molecular pathway on the severity of COVID-19. Current medicinal chemistry, 31 (9), 1142–1151. doi: 10.2174/0929867330666230515144133.
- Bancroft, J. D., and Gamble, M., 2008. Theory and practice of histological techniques. 6th ed. PA, USA: Elsevier health sciences.
- Bao, R., et al., 2020. Improved oral bioavailability and target delivery of 6-shogaol via vitamin E TPGS-modified liposomes: Preparation, in-vitro and in-vivo characterizations. Journal of drug delivery science and technology, 59, 101842. doi: 10.1016/j.jddst.2020.101842.
- Butt, A.M., et al., 2012. In vitro characterization of pluronic F127 and D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles as nanocarriers for targeted anticancer-drug delivery. Journal of nanomaterials, 2012, 112–112.
- Chao, W., et al., 2017. 3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways. International immunopharmacology, 50, 77–86. doi: 10.1016/j.intimp.2017.06.014.
- Cholkar, K., et al., 2015. Nanomicellar topical aqueous drop formulation of rapamycin for back-of-the-eye delivery. AAPS PharmSciTech, 16 (3), 610–622. doi: 10.1208/s12249-014-0244-2.
- Corrêa, J.C.R., and Salgado, H.R.N., 2011. Review of fluconazole properties and analytical methods for its determination. Critical reviews in analytical chemistry, 41 (2), 124–132. doi: 10.1080/10408347.2011.557980.
- Dalmolin, L.F., Khalil, N.M., and Mainardes, R.M., 2016. Delivery of vanillin by poly(lactic-acid) nanoparticles: development, characterization and in vitro evaluation of antioxidant activity. Materials science & engineering. C, materials for biological applications, 62, 1–8. doi: 10.1016/j.msec.2016.01.031.
- Dawoud, M.H., et al., 2023a. A quality by design paradigm for albumin-based nanoparticles: formulation optimization and enhancement of the antitumor activity. Journal of pharmaceutical innovation, 18 (3), 1395–1414. doi: 10.1007/s12247-022-09698-y.
- Dawoud, M.H.S., et al., 2021. Optimization of nanovesicular carriers of a poorly soluble drug using factorial design methodology and artificial neural network by applying quality by design approach. Pharmaceutical development and technology, 26 (10), 1035–1050. doi: 10.1080/10837450.2021.1980009.
- Dawoud, M.H.S., et al., 2023b. Response surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity potential. Drug delivery and translational research, 13 (9), 2315–2339. doi: 10.1007/s13346-023-01315-w.
- EL-Shafei, N.H., et al., 2023. Simvastatin ameliorates testosterone-induced prostatic hyperplasia in rats via modulating IGF-1/PI3K/AKT/FOXO signaling. European journal of pharmacology, 950, 175762. doi: 10.1016/j.ejphar.2023.175762.
- Fatouh, A.M., Elshafeey, A.H., and Abdelbary, A., 2021. Galactosylated chitosan coated liposomes of ledipasvir for liver targeting: chemical synthesis, statistical optimization, in-vitro and in-vivo evaluation. Journal of pharmaceutical sciences, 110 (3), 1148–1159. doi: 10.1016/j.xphs.2020.10.002.
- Feng, T., et al., 2019. Acacia catechu (L.f.) Willd and Scutellaria baicalensis Georgi extracts suppress LPS-induced pro-inflammatory responses through NF-кB, MAPK, and PI3K-Akt signaling pathways in alveolar epithelial type II cells. Phytotherapy research, 33 (12), 3251–3260. doi: 10.1002/ptr.6499.
- Ghanbarzadeh, S., Khorrami, A., and Arami, S., 2014. Preparation of optimized Naproxen nano liposomes using response surface methodology. Journal of pharmaceutical investigation, 44 (1), 33–39. doi: 10.1007/s40005-013-0098-8.
- Ghosh, I., et al., 2012. Optimization of formulation and process parameters for the production of nanosuspension by wet media milling technique: effect of Vitamin E TPGS and nanocrystal particle size on oral absorption. European journal of pharmaceutical sciences: official journal of the european federation for pharmaceutical sciences, 47 (4), 718–728. doi: 10.1016/j.ejps.2012.08.011.
- Gorain, B., et al., 2018. Paclitaxel loaded vitamin E-TPGS nanoparticles for cancer therapy. Materials science & engineering. C, materials for biological applications, 91, 868–880. doi: 10.1016/j.msec.2018.05.054.
- Guideline, I.H.T., 2003. Stability testing of new drug substances and products. Q1A (R2), current step, 4, (1–24.
- Hao, J., et al., 2012. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. European journal of pharmaceutical sciences: official journal of the European federation for pharmaceutical sciences, 47 (2), 497–505. doi: 10.1016/j.ejps.2012.07.006.
- Hoefel, G., Tay, H., and Foster, P., 2019. MicroRNAs in lung diseases. Chest, 156 (5), 991–1000. doi: 10.1016/j.chest.2019.06.008.
- Huang, X., et al., 2019. Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways. European journal of pharmacology, 859, 172481. doi: 10.1016/j.ejphar.2019.172481.
- Isailović, T., et al., 2016. Biocompatible nanoemulsions for improved aceclofenac skin delivery: formulation approach using combined mixture-process experimental design. Journal of pharmaceutical sciences, 105 (1), 308–323. doi: 10.1002/jps.24706.
- Joseph, J., B N, V.H., and D, R.D., 2018. Experimental optimization of Lornoxicam liposomes for sustained topical delivery. European journal of pharmaceutical sciences: official journal of the european federation for pharmaceutical sciences, 112, 38–51. doi: 10.1016/j.ejps.2017.10.032.
- Kfoury, M., et al., 2016. Solubility, photostability and antifungal activity of phenylpropanoids encapsulated in cyclodextrins. Food chemistry, 196, 518–525. doi: 10.1016/j.foodchem.2015.09.078.
- Khoshnam, S.E., et al., 2017. Vanillic acid attenuates effects of transient bilateral common carotid occlusion and reperfusion in rats. Biomedicine & pharmacotherapy = biomedecine & pharmacotherapie, 165, 115061–115674. doi: 10.1016/j.biopha.2023.115061.
- Khurana, S., Bedi, P., and Jain, N, 2012. Development of nanostructured lipid carriers for controlled delivery of mefenamic acid. International journal of biomedical nanoscience and nanotechnology, 2 (3/4), 232–250. doi: 10.1504/IJBNN.2012.051218.
- Kiokias, S., Proestos, C., and Oreopoulou, V., 2020. Phenolic acids of plant origin—A review on their antioxidant activity in vitro (o/w emulsion systems) along with their in vivo health biochemical properties. Foods, 9 (4), 534. doi: 10.3390/foods9040534.
- Kotta, S., et al., 2021. Lung targeted lipopolymeric microspheres of dexamethasone for the treatment of ARDS. Pharmaceutics, 13 (9), 1347. doi: 10.3390/pharmaceutics13091347.
- Li, J., et al., 2016. Vitamin E TPGS modified liposomes enhance cellular uptake and targeted delivery of luteolin: an in vivo/in vitro evaluation. International journal of pharmaceutics, 512 (1), 262–272. doi: 10.1016/j.ijpharm.2016.08.037.
- Li, Y., et al., 2020b. Inhibition of miR-217 protects against myocardial ischemia-reperfusion injury through Inactivating NF-κB and MAPK Pathways. Cardiovascular engineering and technology, 11 (2), 219–227. doi: 10.1007/s13239-019-00452-z.
- Liu, B., et al., 2020. Emodin improves alveolar hypercoagulation and inhibits pulmonary inflammation in LPS-provoked ARDS in mice via NF-κB inactivation. International immunopharmacology, 88, 107020. doi: 10.1016/j.intimp.2020.107020.
- Liu, H., et al., 2016. The effect of surfactant on paclitaxel nanocrystals: an in vitro and in vivo study. Journal of biomedical nanotechnology, 12 (1), 147–153. doi: 10.1166/jbn.2016.2127.
- Liu, Y., et al., 2019. Preparation and characterization of syringic acid–loaded TPGS liposome with enhanced oral bioavailability and in vivo antioxidant efficiency. AAPS PharmSciTech, 20 (3), 98. doi: 10.1208/s12249-019-1290-6.
- Li, T., et al., 2020a. Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway. Molecular immunology, 120, 13–22. doi: 10.1016/j.molimm.2020.01.014.
- Maritim, S., Boulas, P., and Lin, Y., 2021. Comprehensive analysis of liposome formulation parameters and their influence on encapsulation, stability and drug release in glibenclamide liposomes. International journal of pharmaceutics, 592, 120051. doi: 10.1016/j.ijpharm.2020.120051.
- Mi, Y., Zhao, J., and Feng, S.-S., 2012. Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects. International journal of pharmaceutics, 438 (1–2), 98–106. doi: 10.1016/j.ijpharm.2012.08.038.
- Morsi, N.M., Aboelwafa, A.A., and Dawoud, M.H., 2016. Improved bioavailability of timolol maleate via transdermal transfersomal gel: Statistical optimization, characterization, and pharmacokinetic assessment. Journal of advanced research, 7 (5), 691–701. doi: 10.1016/j.jare.2016.07.003.
- Morsi, N.M., Aboelwafa, A.A., and Dawoud, M.H.S., 2018. Enhancement of the bioavailability of an antihypertensive drug by transdermal protransfersomal system: formulation and in vivo study. Journal of liposome research, 28 (2), 137–148. doi: 10.1080/08982104.2017.1295989.
- Muthu, M.S., et al., 2011. Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells. International journal of pharmaceutics, 421 (2), 332–340. doi: 10.1016/j.ijpharm.2011.09.045.
- Nekkanti, V., Venkatesan, N., and Betageri, G.V., 2015. Proliposomes for oral delivery: progress and challenges. Current pharmaceutical biotechnology, 16 (4), 303–312. doi: 10.2174/1389201016666150118134256.
- Shao, Y., Yang, L., and Han, H.-K., 2015. TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10. European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 89, 339–346. doi: 10.1016/j.ejpb.2014.12.026.
- Sharma, N., Madan, P., and Lin, S., 2016. Effect of process and formulation variables on the preparation of parenteral paclitaxel-loaded biodegradable polymeric nanoparticles: A co-surfactant study. Asian journal of pharmaceutical sciences. 11 (3), 404–416. doi: 10.1016/j.ajps.2015.09.004.
- Singh, A., et al., 2021. Novel vitamin E TPGS based docetaxel nanovesicle formulation for its safe and effective parenteral delivery: toxicological, pharmacokinetic and pharmacodynamic evaluation. Journal of liposome research, 31 (4), 365–380. doi: 10.1080/08982104.2020.1835955.
- Sun, C., et al., 2020. Development of TPGS/F127/F68 mixed polymeric micelles: enhanced oral bioavailability and hepatoprotection of syringic acid against carbon tetrachloride-induced hepatotoxicity. Food and chemical toxicology: an international journal published for the British industrial biological research association, 137, 111126. doi: 10.1016/j.fct.2020.111126.
- Tefas, L.R., et al., 2015. Quercetin-loaded liposomes: formulation optimization through a D-optimal experimental design. Farmacia, 63, 26–33.
- Wang, H.L., et al., 2014. Hydroxycamptothecin stealth liposomes: containing TPGS as a novel PEGylated long-circulating coating material. Advanced materials research, 886, 333–336. doi: 10.4028/www.scientific.net/AMR.886.333.
- Xu, J., et al., 2017. Design and evaluation of novel solid self-nanodispersion delivery system for andrographolide. AAPS PharmSciTech, 18 (5), 1572–1584. doi: 10.1208/s12249-016-0627-7.
- Yan, J., et al., 2021. MicroRNA-217 modulates inflammation, oxidative stress, and lung injury in septic mice via SIRT1. Free radical research, 55 (1), 1–10. doi: 10.1080/10715762.2020.1852234.
- Yu, J.-N., et al., 2010. Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles. Acta pharmacologica Sinica, 31 (6), 759–764. doi: 10.1038/aps.2010.55.
- Zaafan, M.A., and Abdelhamid, A.M., 2021. The cardioprotective effect of microRNA-103 inhibitor against isoprenaline-induced myocardial infarction in mice through targeting FADD/RIPK pathway. European review for medical and pharmacological sciences, 25 (2), 837–844. doi: 10.26355/eurrev_202101_24648.
- Zaafan, M.A., and Abdelhamid, A.M., 2022. Dasatinib ameliorates thioacetamide-induced liver fibrosis: modulation of miR-378 and miR-17 and their linked Wnt/β-catenin and TGF-β/smads pathways. Journal of enzyme inhibition and medicinal chemistry, 37 (1), 118–124. doi: 10.1080/14756366.2021.1995379.
- Zaafan, M.A., Haridy, A.R., and Abdelhamid, A.M., 2019. Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2. Naunyn-Schmiedeberg’s archives of pharmacology, 392 (3), 279–286. doi: 10.1007/s00210-018-1586-1.
- Zaafan, M.A., et al., 2016. Pyrrolidinedithiocarbamate attenuates bleomycin-induced pulmonary fibrosis in rats: modulation of oxidative stress, fibrosis, and inflammatory parameters. Experimental lung research, 42 (8–10), 408–416. doi: 10.1080/01902148.2016.1244578.
- Zhang, Z., Tan, S., and Feng, S.-S., 2012. Vitamin E TPGS as a molecular biomaterial for drug delivery. Biomaterials, 33 (19), 4889–4906. doi: 10.1016/j.biomaterials.2012.03.046.
- Zhao, X., et al., 2012. Optimization on condition of glycyrrhetinic acid liposome by RSM and the research of its immunological activity. International journal of biological macromolecules, 51 (3), 299–304. doi: 10.1016/j.ijbiomac.2012.05.005.
- Zhu, Y., et al., 2015. Improved oral bioavailability of capsaicin via liposomal nanoformulation: preparation, in vitro drug release and pharmacokinetics in rats. Archives of pharmacal research, 38 (4), 512–521. doi: 10.1007/s12272-014-0481-7.