129
Views
6
CrossRef citations to date
0
Altmetric
Original

Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury

, MD, , , , , & show all
Pages 611-615 | Received 08 Feb 2008, Accepted 12 May 2008, Published online: 03 Jul 2009

References

  • Franz G, Beer R, Kampfl A, Engelhardt K, Schmutzhard E, Ulmer H, Deisenhammer F. Amyloid beta 1-42 and tau in cerebrospinal fluid after severe traumatic brain injury. Neurology 2003; 60: 1457–1461
  • Zemlan FP, Rosenberg WS, Puebbe PA, Campbell TA, Dean GE, Weiner NE, Cohen JA, Rudick RA, Woo D. Quarification of axonal damage in traumatic brain injury: affinity purification and characterization of cerebrospinal fluid tau proteins. Journal of Neurochemistry 1999; 72: 741–750
  • Zemlan FP, Jauch EC, Muchahey JJ, Gabbita SP, Rosenberg WS, Speciale SG, Zuccarello M. C-tau biomarker of neuronal damage in severe brain injured patients; association with elevated intracranil pressure and clinical outcome. Brain Research 2002; 947: 131–139
  • Gabbita SP, Scheff SW, Menard RM, Roberts K, Fugaccia I, Zemlan FP. Cleaved-tau: a biomarker of neuronal damage after traumatic brain injury. Journal of Neurotrauma 2005; 22: 83–94
  • Ringger NC, O'Steen BE, Brabjam JG, Silver X, Pineda J, Wang KK, Hayes RL, Papa L. A novel marker for traumatic brain injury: CSF alpha II-spectrin breakdown product levels. Journal of Neurotrauma 2004; 21: 1443–1456
  • Kleindienst A, Hesse F, Bullock MR, Buchfelder M. The neurotrophic protein S100B: value as a marker of brain damage and possible therapeutic implications. Progress in Brain Research 2007; 161: 317–325
  • Hardemark HG, Ericcson N, Kotwica Z, Rundstrom G, Mendel-Hartvig I, Olsson Y, Pahlman S, Persson L. S-100 protein and neuron-specific enolase in CSF after experimental trauma or focal ischemic brain damage. Journal of Neurosurgery 1989; 71: 727–731
  • Berger RP, Adelson PD, Pierce MC, Dulani T, Cassidy LD, Kochanek PM. Serum neuron-specific enolase, S10-0B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children. Journal of Neurosurgery 2005; 103(Suppl 1)61–68
  • Weiss N, Sanchez-Pena P, Roche S, Beaudeux JL, Colonne C, Coriat P, Puybasset L. Prognosis value of plasma S100B protein levels after subarachnoid anueurysmal hemorrhage. Anesthesiology 2006; 104: 658–666
  • Dietschy JM, Turley SD. Cholesterol metabolism in the central nervous system during early development and in the mature animal. Journal of Lipid Research 2004; 45: 1375–1397
  • Björkhem I, Meaney S. Brain cholesterol: long secret life behind a barrier. Arterosclerosis, Thrombosis and Vascular Biology 2004; 24: 806–815
  • Björkhem I, Lütjohann D, Diczfalusy U, Stahle L, Ahlborg G, Wahren J. Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in circulation. Journal of Lipid Research 1998; 39: 1594–1600
  • Lund EG, Guileyardo JM, Russell DW. CDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proceedings of the National Academy of Sciences (USA) 1999; 96: 7238–7243
  • Lütjohann D, Breuer G, Ahlborg I. Siden Å, Diczfalusy U, Björkem I. Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proceedings of the National Academy of Sciences (USA) 1996; 93: 9799–9804
  • Bretillon L, Lütjohann D, Ståhle L, Widhe T, Bindl L, Eggertsen G, Diczfalusy U, Björkhem I. Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface. Journal of Lipid Research 2000; 41: 840–845
  • Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974; 2: 81–84
  • Osler T, Baker SP, Long W. A modification of the Injury Severity Score that both improves accuracy and simplifies scoring. Journal of Trauma 1997; 43: 922–925
  • Vega GL, Weiner MF, Lipton AM, von Bergmann K, Lütjohann D, Moore C, Svetlik D. Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. Archives of Neurology 2003; 60: 510–515
  • Lütjohann D, Björkem I, Beil UF, von Bergmann K. Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment. Journal of Lipid Research 1995; 36: 1763–1773
  • Lütjohann D, Papassotiropoulos A, Björkem I, Locatelli S, Bagli M, Oehring RD, Schlegel U, Jessen F, Rao ML, von Bergmann K, Heun R. Plasma 24S-hydroxycholesterol (cerebrosterol) in increased in Alzheimer and vascular demented patients. Journal of Lipid Research 2000; 41: 195–198
  • Vega GL, Weiner MF, Kölsch H, von Bergmann K, Heun R, Lütjohann D, Nguyen A, Moore C. The effects of gender and CYP 246 and apoE polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins. Current Alzheimers Research 2004; 1: 71–77
  • Holdenreider S, Lütjohann D, Geiger S, von Bergmann K, Stieber P, Hamman GF. Does brain-specific 24S-hydroxycholesterol in plasma indicate disruption of the blood-brain barrier in patients with ischemeic stroke?. Neuroscience Letters 2004; 368: 201–204
  • Dunham CM, Fealk MH, Sever WE, 3rd. Following severe injury, hypocholesterolemia improves with convalescence but persists with organ failure or onset of infection. Critical Care 2003; 7: 413–414
  • Bakalar B, Hyspler R, Pachl J, Zadak Z. Changes in cholesterol and its precursors during the first days after major trauma. Wiener Klinische Wochenschrift 2003; 115: 9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.